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Volumn 20, Issue 4, 2003, Pages 337-345

Tempol, a novel stable nitroxide, reduces brain damage and free radical production, after acute subdural hematoma in the rat

Author keywords

Acute subdural hematoma; Free radical; Ischemic brain damage; Microdialysis; Nitroxide

Indexed keywords

2,3 DIHYDROXYBENZOIC ACID; FREE RADICAL; GENTISIC ACID; NITROXIDE DERIVATIVE; SALICYLIC ACID; SUPEROXIDE DISMUTASE; TEMPOL;

EID: 0037731669     PISSN: 08977151     EISSN: None     Source Type: Journal    
DOI: 10.1089/089771503765172291     Document Type: Article
Times cited : (37)

References (55)
  • 1
    • 0021007930 scopus 로고
    • Head injury in man and experimental animals: Neuropathology
    • ADAMS, J.H., GRAHAM, D.I., and GENNARELLI, T.A. (1983). Head injury in man and experimental animals: neuropathology. Acta Neurochir. Suppl. 32, 15-30.
    • (1983) Acta Neurochir. Suppl. , vol.32 , pp. 15-30
    • Adams, J.H.1    Graham, D.I.2    Gennarelli, T.A.3
  • 2
    • 0023067094 scopus 로고
    • Cytotoxicity of commonly used nitroxide radical spin probes
    • ANKEL, E.G., LAI, C.S., HOPWOOD, L.E., et al. (1987). Cytotoxicity of commonly used nitroxide radical spin probes. Life Sci. 40, 495-498.
    • (1987) Life Sci. , vol.40 , pp. 495-498
    • Ankel, E.G.1    Lai, C.S.2    Hopwood, L.E.3
  • 3
    • 0031754206 scopus 로고    scopus 로고
    • Polynitroxyl albumin reduces infarct size in transient focal ischemia in the rat: Potential mechanisms studied by magnetic resonance imaging
    • BEAULIEU, C., BUSCH, E., ROTHER, J., et al. (1998). Polynitroxyl albumin reduces infarct size in transient focal ischemia in the rat: potential mechanisms studied by magnetic resonance imaging. J. Cereb. Blood Flow Metab. 18, 1022-1031.
    • (1998) J. Cereb. Blood Flow Metab. , vol.18 , pp. 1022-1031
    • Beaulieu, C.1    Busch, E.2    Rother, J.3
  • 4
    • 0029933628 scopus 로고    scopus 로고
    • Cerebroprotective effect of stable nitroxide radicals in closed head injury in the rat
    • BEIT-YANNAI, E., ZHANG, R., TREMBOVLER, V., et al. (1996). Cerebroprotective effect of stable nitroxide radicals in closed head injury in the rat. Brain Res. 717, 22-28.
    • (1996) Brain Res. , vol.717 , pp. 22-28
    • Beit-Yannai, E.1    Zhang, R.2    Trembovler, V.3
  • 5
    • 0024520513 scopus 로고
    • Central nervous system trauma and stroke. I. Biochemical considerations for oxygen radical formation and lipid peroxidation
    • BRAUGHLER, M.J., and HALL, E.D. (1989). Central nervous system trauma and stroke. I. Biochemical considerations for oxygen radical formation and lipid peroxidation. Free Radic. Biol. Med. 6, 289-301.
    • (1989) Free Radic. Biol. Med. , vol.6 , pp. 289-301
    • Braughler, M.J.1    Hall, E.D.2
  • 6
    • 0000679618 scopus 로고
    • Surgical management of traumatic intracranial haematomas
    • R. Braakman (ed), Elsevier Science Publishers: Amsterdam
    • BULLOCK, R., and TEASDALE, G.M. (1991). Surgical management of traumatic intracranial haematomas, in: Vinken and Bryun's Handbook of Clinical Neurology: Vol. 24. Head Injury. R. Braakman (ed), Elsevier Science Publishers: Amsterdam, pps. 249-298.
    • (1991) Vinken and Bryun's Handbook of Clinical Neurology: Vol. 24. Head Injury , vol.24 , pp. 249-298
    • Bullock, R.1    Teasdale, G.M.2
  • 7
    • 0034055967 scopus 로고    scopus 로고
    • 4-Hydroxy-2,2,6,6-tetramethylpiperidine-1-oxyl (Tempol) inhibits peroxynitrite-mediated phenol nitration
    • CARROLL, R.T., GALATSIS, P., BOROSKY, S., et al. (2000). 4-Hydroxy-2,2,6,6-tetramethylpiperidine-1-oxyl (Tempol) inhibits peroxynitrite-mediated phenol nitration. Chem. Res. Toxicol. 13, 294-300.
    • (2000) Chem. Res. Toxicol. , vol.13 , pp. 294-300
    • Carroll, R.T.1    Galatsis, P.2    Borosky, S.3
  • 8
    • 0034284555 scopus 로고    scopus 로고
    • Effects of tempol, a membrane-permeable radical scavenger, in a gerbil model of brain injury
    • CUZZOCREA, S., MCDONALD, M.C., MAZZON, E., et al. (2000). Effects of tempol, a membrane-permeable radical scavenger, in a gerbil model of brain injury. Brain Res. 875, 96-106.
    • (2000) Brain Res. , vol.875 , pp. 96-106
    • Cuzzocrea, S.1    Mcdonald, M.C.2    Mazzon, E.3
  • 9
    • 0019268092 scopus 로고
    • The free radical pathology and the microcirculation in the major central nervous system disorders
    • DEMOPOULOS, H.B., FLAMM, E.S., PIETRONIGRO, D.D., et al. (1980). The free radical pathology and the microcirculation in the major central nervous system disorders. Acta Physiol. Scand. 492, Suppl, 91-119.
    • (1980) Acta Physiol. Scand. , vol.492 , Issue.SUPPL. , pp. 91-119
    • Demopoulos, H.B.1    Flamm, E.S.2    Pietronigro, D.D.3
  • 10
    • 0030941106 scopus 로고    scopus 로고
    • Clinical neuroprotection trials in severe traumatic head injury: Lessons from previous studies
    • DOPPENBERG, E., and BULLOCK, R. (1997). Clinical neuroprotection trials in severe traumatic head injury: lessons from previous studies. J. Neurotrauma 14, 71-79.
    • (1997) J. Neurotrauma , vol.14 , pp. 71-79
    • Doppenberg, E.1    Bullock, R.2
  • 11
    • 0031968901 scopus 로고    scopus 로고
    • Increased free radical production due to subdural hematoma in the rat: Effect of increased inspired oxygen fraction
    • DOPPENBERG, E.M.R., RICE, M.R., DI, X., et al. (1998). Increased free radical production due to subdural hematoma in the rat: effect of increased inspired oxygen fraction. J. Neurotrauma 15, 337-347.
    • (1998) J. Neurotrauma , vol.15 , pp. 337-347
    • Doppenberg, E.M.R.1    Rice, M.R.2    Di, X.3
  • 12
    • 0019504931 scopus 로고
    • Oxidative metabolic activity of cerebral cortex after fluid-percussion injury in the cat
    • DUCKROW, R.B., LAMANNA, J.C., and ROSENTHAL, M. (1986). Oxidative metabolic activity of cerebral cortex after fluid-percussion injury in the cat. J. Neurosurg. 54, 607-614.
    • (1986) J. Neurosurg. , vol.54 , pp. 607-614
    • Duckrow, R.B.1    Lamanna, J.C.2    Rosenthal, M.3
  • 13
    • 0028864283 scopus 로고
    • Induction of heme oxygenase-1 (HO-1) after traumatic brain injury in the rat
    • FUKUDA, K., PANTER, S.S., SHARP, F.R., et al. (1995). Induction of heme oxygenase-1 (HO-1) after traumatic brain injury in the rat. Neurosci. Lett. 199, 127-130.
    • (1995) Neurosci. Lett. , vol.199 , pp. 127-130
    • Fukuda, K.1    Panter, S.S.2    Sharp, F.R.3
  • 14
    • 0025881720 scopus 로고
    • Cardiac reperfusion damage prevented by a nitroxide free radical
    • GELVAN, D., SALTMAN, P., and POWELL, S.R. (1991). Cardiac reperfusion damage prevented by a nitroxide free radical. Proc. Natl. Acad. Sci. USA 88, 4680-4684.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 4680-4684
    • Gelvan, D.1    Saltman, P.2    Powell, S.R.3
  • 15
    • 0019969679 scopus 로고
    • Influence of the type of intracranial lesion on outcome from severe head injury: A multicenter study using a new classification system
    • GENNARELLI, T.A., SPIELMAN, G.M., LANGFITT, T.W., et al. (1982). Influence of the type of intracranial lesion on outcome from severe head injury: a multicenter study using a new classification system. J. Neurosurg. 56, 26-32.
    • (1982) J. Neurosurg. , vol.56 , pp. 26-32
    • Gennarelli, T.A.1    Spielman, G.M.2    Langfitt, T.W.3
  • 16
    • 0029130550 scopus 로고
    • Glutamate release and free radical production following brain injury: Effects of post-traumatic hypothermia
    • GLOBUS, M.Y., ALONSO, O., DIETRICH, W.D., et al. (1995a). Glutamate release and free radical production following brain injury: effects of post-traumatic hypothermia. J. Neurochem. 65, 1704-1711.
    • (1995) J. Neurochem. , vol.65 , pp. 1704-1711
    • Globus, M.Y.1    Alonso, O.2    Dietrich, W.D.3
  • 17
    • 0029112937 scopus 로고
    • Detection of free radical activity during transient global ischemia and recirculation: Effects of intraischemic brain temperature modulation
    • GLOBUS, M.Y., BUSTO, R., LIN, B., et al. (1995b). Detection of free radical activity during transient global ischemia and recirculation: effects of intraischemic brain temperature modulation. J. Neurochem. 65, 1250-1256.
    • (1995) J. Neurochem. , vol.65 , pp. 1250-1256
    • Globus, M.Y.1    Busto, R.2    Lin, B.3
  • 18
    • 0018129225 scopus 로고
    • Ischemic brain damage in fatal non-missile head injuries
    • GRAHAM, D.I., ADAMS, J.H., and DOYLE, D. (1978). Ischemic brain damage in fatal non-missile head injuries. J. Neurol. Sci. 39, 213-234.
    • (1978) J. Neurol. Sci. , vol.39 , pp. 213-234
    • Graham, D.I.1    Adams, J.H.2    Doyle, D.3
  • 20
    • 0032856649 scopus 로고    scopus 로고
    • Hemodynamic effect of the nitroxide superoxide dismutase mimics
    • HAHN, S.M., SULLIVAN, F.J., DELUCA, A.M., et al. (1999). Hemodynamic effect of the nitroxide superoxide dismutase mimics. Free Radic. Biol. Med. 27, 529-535.
    • (1999) Free Radic. Biol. Med. , vol.27 , pp. 529-535
    • Hahn, S.M.1    Sullivan, F.J.2    Deluca, A.M.3
  • 21
    • 0031112374 scopus 로고    scopus 로고
    • Brain attack. Acute therapeutic interventions: Free radical scavengers and antioxidants
    • HALL, E.D. (1997). Brain attack. Acute therapeutic interventions: free radical scavengers and antioxidants. Neurosurg. Clin. North Am. 8, 195-206.
    • (1997) Neurosurg. Clin. North Am. , vol.8 , pp. 195-206
    • Hall, E.D.1
  • 22
    • 0027301060 scopus 로고
    • Lipid antioxidants in acute central nervous system injury
    • HALL, E.D. (1993a). Lipid antioxidants in acute central nervous system injury. Ann. Emerg. Med. 22, 1022-1027.
    • (1993) Ann. Emerg. Med. , vol.22 , pp. 1022-1027
    • Hall, E.D.1
  • 23
    • 0027389031 scopus 로고
    • The role of oxygen radicals in traumatic injury: Clinical implications
    • HALL, E.D. (1993b). The role of oxygen radicals in traumatic injury: clinical implications. J. Emerg. Med. 11, Suppl 1, 31-36.
    • (1993) J. Emerg. Med. , vol.11 , Issue.SUPPL. 1 , pp. 31-36
    • Hall, E.D.1
  • 24
    • 0027400110 scopus 로고
    • Brain hydroxyl radical generation in acute experimental head injury
    • HALL, E.D., ANDRUS, P.K., and YONKERS, P.A. (1993). Brain hydroxyl radical generation in acute experimental head injury. J. Neurochem. 60, 588-594.
    • (1993) J. Neurochem. , vol.60 , pp. 588-594
    • Hall, E.D.1    Andrus, P.K.2    Yonkers, P.A.3
  • 25
    • 0024589421 scopus 로고
    • Central nervous system trauma and stroke. Physiological and pharmacological evidence for involvement of oxygen radicals and lipid peroxidation
    • HALL, E.D., and BRAUGHLER, J.M. (1989). Central nervous system trauma and stroke. Physiological and pharmacological evidence for involvement of oxygen radicals and lipid peroxidation. Free Radic. Biol. Med. 6, 303-313.
    • (1989) Free Radic. Biol. Med. , vol.6 , pp. 303-313
    • Hall, E.D.1    Braughler, J.M.2
  • 26
    • 0026754574 scopus 로고
    • Reactive oxygen species and the central nervous system
    • HALLIWELL, B. (1992). Reactive oxygen species and the central nervous system. J. Neurochem. 59, 1609-1623.
    • (1992) J. Neurochem. , vol.59 , pp. 1609-1623
    • Halliwell, B.1
  • 27
    • 0015382153 scopus 로고
    • Surgically treated traumatic subdural haematomas
    • JAMIESON, K.G., and YELLAND, J.D.N. (1972). Surgically treated traumatic subdural haematomas. J. Neurosurg. 37, 137-149.
    • (1972) J. Neurosurg. , vol.37 , pp. 137-149
    • Jamieson, K.G.1    Yelland, J.D.N.2
  • 28
  • 29
    • 0022133358 scopus 로고
    • Oxygen radicals in cerebral vascular injury
    • KONTOS, H.A. (1985). Oxygen radicals in cerebral vascular injury. Circ. Res. 57, 508-516.
    • (1985) Circ. Res. , vol.57 , pp. 508-516
    • Kontos, H.A.1
  • 30
    • 0022628380 scopus 로고
    • Superoxide production in experimental brain injury
    • KONTOS, H.A., and WEI, E.P. (1986). Superoxide production in experimental brain injury. J. Neurosurg. 64, 803-807.
    • (1986) J. Neurosurg. , vol.64 , pp. 803-807
    • Kontos, H.A.1    Wei, E.P.2
  • 31
    • 0036403099 scopus 로고    scopus 로고
    • The nitroxide antioxidant tempol is cerebroprotective against focal cerebral ischemia in spontaneously hypertensive rats
    • LEKER, R.R., TEICHNER, A., LAVIE, G., et al. (2002). The nitroxide antioxidant tempol is cerebroprotective against focal cerebral ischemia in spontaneously hypertensive rats. Exp. Neurol. 176, 355-363.
    • (2002) Exp. Neurol. , vol.176 , pp. 355-363
    • Leker, R.R.1    Teichner, A.2    Lavie, G.3
  • 32
    • 0003091190 scopus 로고    scopus 로고
    • Pathology and pathophysiology of head injury
    • J.R. Youmans (ed), W.B. Saunders: Philadelphia
    • LIAU, L.M., BERGSNEIDER, M., and BECKER, D.P. (1996). Pathology and pathophysiology of head injury, in: Neurological Surgery, Vol. 3, 4th ed. J.R. Youmans (ed), W.B. Saunders: Philadelphia, pps. 1576-1585.
    • (1996) Neurological Surgery, Vol. 3, 4th Ed. , vol.3 , pp. 1576-1585
    • Liau, L.M.1    Bergsneider, M.2    Becker, D.P.3
  • 33
    • 0023731036 scopus 로고
    • Heme oxygenase: Function, multiplicity, regulatory mechanisms, and clinical applications
    • MAINES, M.D. (1988). Heme oxygenase: function, multiplicity, regulatory mechanisms, and clinical applications. FASEB J. 2, 2557-2568.
    • (1988) FASEB J. , vol.2 , pp. 2557-2568
    • Maines, M.D.1
  • 34
    • 0028805577 scopus 로고
    • Pitfalls and advances from the international tirilazad trial in moderate and severe head injury
    • MARSHALL, L., and MARSHALL, S.B. (1995). Pitfalls and advances from the international tirilazad trial in moderate and severe head injury. J. Neurotrauma 12, 929-932.
    • (1995) J. Neurotrauma , vol.12 , pp. 929-932
    • Marshall, L.1    Marshall, S.B.2
  • 35
    • 0029868298 scopus 로고    scopus 로고
    • Heme-oxygenase-1 induction in glia throughout rat brain following experimental subarachnoid hemorrhage
    • MATZ, P., TURNER, C., WEINSTEIN, P.R., et al. (1996). Heme-oxygenase-1 induction in glia throughout rat brain following experimental subarachnoid hemorrhage. Brain Res. 713, 211-222.
    • (1996) Brain Res. , vol.713 , pp. 211-222
    • Matz, P.1    Turner, C.2    Weinstein, P.R.3
  • 36
    • 0031032288 scopus 로고    scopus 로고
    • Heme oxygenase-1 and heat shock protein 70 induction in glia and neurons throughout rat brain after experimental intracerebral hemorrhage
    • MATZ, P.G., WEINSTEIN, P.R., and SHARP, F.R. (1997). Heme oxygenase-1 and heat shock protein 70 induction in glia and neurons throughout rat brain after experimental intracerebral hemorrhage. Neurosurgery 40, 152-162.
    • (1997) Neurosurgery , vol.40 , pp. 152-162
    • Matz, P.G.1    Weinstein, P.R.2    Sharp, F.R.3
  • 37
    • 0021984681 scopus 로고
    • Oxygen-derived free radicals in postischemic injury
    • MCCORD, J. (1985). Oxygen-derived free radicals in postischemic injury. N. Engl. J. Med. 312, 159-163.
    • (1985) N. Engl. J. Med. , vol.312 , pp. 159-163
    • Mccord, J.1
  • 38
    • 0025130511 scopus 로고
    • Ischemic brain damage in a model of acute subdural hematoma
    • MILLER, J.D., BULLOCK, R., GRAHAM, D.I., et al. (1990). Ischemic brain damage in a model of acute subdural hematoma. Neurosurgery 27, 433-439.
    • (1990) Neurosurgery , vol.27 , pp. 433-439
    • Miller, J.D.1    Bullock, R.2    Graham, D.I.3
  • 39
    • 0019423150 scopus 로고
    • Further experience in the management of severe head injury
    • MILLER, J.D., BUTTERWORTH, J.F., GUDEMAN, S.K., et al. (1981). Further experience in the management of severe head injury. J. Neurosurg. 54, 289-299.
    • (1981) J. Neurosurg. , vol.54 , pp. 289-299
    • Miller, J.D.1    Butterworth, J.F.2    Gudeman, S.K.3
  • 40
    • 0025322028 scopus 로고
    • Biologically active metal independent superoxide dismutase mimics
    • MITCHELL, J.B., SAMUNI, A., KRISHNA, M.C., et al. (1990). Biologically active metal independent superoxide dismutase mimics. Biochemistry 29, 2802-2807.
    • (1990) Biochemistry , vol.29 , pp. 2802-2807
    • Mitchell, J.B.1    Samuni, A.2    Krishna, M.C.3
  • 41
    • 0030028586 scopus 로고    scopus 로고
    • Simultaneous measurement of salicylate hydroxylation and glutamate release in the penumbral cortex following transient middle cerebral artery occlusion in rats
    • MORIMOTO, T., GLOBUS, M.Y., BUSTO, R., et al. (1996). Simultaneous measurement of salicylate hydroxylation and glutamate release in the penumbral cortex following transient middle cerebral artery occlusion in rats. J. Cereb. Blood Flow Metab. 16, 92-99.
    • (1996) J. Cereb. Blood Flow Metab. , vol.16 , pp. 92-99
    • Morimoto, T.1    Globus, M.Y.2    Busto, R.3
  • 42
    • 0027161790 scopus 로고
    • Cerebral ischemia-reperfusion injury after severe head injury and its possible treatment with polyethylene glycol-superoxide dismutase
    • MUIZELAAR, J.P. (1993). Cerebral ischemia-reperfusion injury after severe head injury and its possible treatment with polyethylene glycol-superoxide dismutase. Ann. Emerg. Med. 22, 1014-1021.
    • (1993) Ann. Emerg. Med. , vol.22 , pp. 1014-1021
    • Muizelaar, J.P.1
  • 43
    • 0025260736 scopus 로고
    • Excitatory amino acid release and free radical formation may cooperate in the genesis of ischemia-induced neuronal damage
    • OLIVER, C.N., STARKE-REED, P.E., STADTMAN, E.R., et al. (1990). Excitatory amino acid release and free radical formation may cooperate in the genesis of ischemia-induced neuronal damage. J. Neurosci. 10, 1035-1041.
    • (1990) J. Neurosci. , vol.10 , pp. 1035-1041
    • Oliver, C.N.1    Starke-Reed, P.E.2    Stadtman, E.R.3
  • 44
    • 0023127128 scopus 로고
    • Quantitative assessment of early brain damage in a rat model of focal cerebral ischaemia
    • OSBORNE, K.A., SHIGENO, T., BALARSKY, A.M., et al. (1987). Quantitative assessment of early brain damage in a rat model of focal cerebral ischaemia. J. Neurol. Neurosurg. Psychiatry 50, 402-410.
    • (1987) J. Neurol. Neurosurg. Psychiatry , vol.50 , pp. 402-410
    • Osborne, K.A.1    Shigeno, T.2    Balarsky, A.M.3
  • 45
    • 0034080954 scopus 로고    scopus 로고
    • Neuroprotection by the stable nitroxide Tempol during reperfusion in a rat model of transient focal ischemia
    • RAK, R., CHAO, D.L., PLUTA, R.M., et al. (2000). Neuroprotection by the stable nitroxide Tempol during reperfusion in a rat model of transient focal ischemia. J. Neurosurg. 92, 646-651.
    • (2000) J. Neurosurg. , vol.92 , pp. 646-651
    • Rak, R.1    Chao, D.L.2    Pluta, R.M.3
  • 46
    • 0026032484 scopus 로고
    • Nitroxides block DNA scission and protect cells from oxidative damage
    • SAMUNI, A., GODINGER, D., ARONVITCH, J., et al. (1991). Nitroxides block DNA scission and protect cells from oxidative damage. Biochemistry 30, 555-561.
    • (1991) Biochemistry , vol.30 , pp. 555-561
    • Samuni, A.1    Godinger, D.2    Aronvitch, J.3
  • 47
    • 0031926961 scopus 로고    scopus 로고
    • Normalization of blood pressure and renal vascular resistance in SHR with a membrane-permeable superoxide dismutase mimetic: Role of nitric oxide
    • SCHNACKENBERG, C.G., WELCH, W.J., and WILCOX, C.S. (1998). Normalization of blood pressure and renal vascular resistance in SHR with a membrane-permeable superoxide dismutase mimetic: role of nitric oxide. Hypertension 32, 59-64.
    • (1998) Hypertension , vol.32 , pp. 59-64
    • Schnackenberg, C.G.1    Welch, W.J.2    Wilcox, C.S.3
  • 48
    • 0019480307 scopus 로고
    • Tramatic acute subdural hematoma. Major mortality reduction in comatose patients treated within four hours
    • SEELIG, J.M., BECKER, D.P., MILLER, J.D., et al. (1981). Traumatic acute subdural hematoma. Major mortality reduction in comatose patients treated within four hours. N. Engl. J. Med. 304, 1511-1518.
    • (1981) N. Engl. J. Med. , vol.304 , pp. 1511-1518
    • Seelig, J.M.1    Becker, D.P.2    Miller, J.D.3
  • 49
    • 0027440127 scopus 로고
    • Oxypurinol inhibits free radical release from the cerebral cortex of closed head injured rats
    • SEN, S., GOLDMAN, H., MOREHEAD, M., et al. (1993). Oxypurinol inhibits free radical release from the cerebral cortex of closed head injured rats. Neurosci. Lett. 162, 117-120.
    • (1993) Neurosci. Lett. , vol.162 , pp. 117-120
    • Sen, S.1    Goldman, H.2    Morehead, M.3
  • 50
    • 0027198869 scopus 로고
    • Basic mechanism of traumatic brain damage
    • SIESJO, B.K. (1993). Basic mechanism of traumatic brain damage. Ann. Emerg. Med. 22, 959-969.
    • (1993) Ann. Emerg. Med. , vol.22 , pp. 959-969
    • Siesjo, B.K.1
  • 52
    • 0020698030 scopus 로고
    • Subdural hematomas. I. Acute subdural hematoma: Progress in definition, clinical pathology and therapy
    • STONE, J.L., RIFAI, M.H.S., SUGAR, O., et al. (1983). Subdural hematomas. I. Acute subdural hematoma: progress in definition, clinical pathology and therapy. Surg. Neurol. 19, 216-231.
    • (1983) Surg. Neurol. , vol.19 , pp. 216-231
    • Stone, J.L.1    Rifai, M.H.S.2    Sugar, O.3
  • 53
    • 0025364999 scopus 로고
    • Acute subdural hematoma: Morbidity and mortality related to timing of operative intervention
    • WILBERGER, J.E., HARRIS, M., and DIAMOND, D.L. (1990). Acute subdural hematoma: morbidity and mortality related to timing of operative intervention. J. Trauma 30, 733-736.
    • (1990) J. Trauma , vol.30 , pp. 733-736
    • Wilberger, J.E.1    Harris, M.2    Diamond, D.L.3
  • 54
    • 0029761661 scopus 로고    scopus 로고
    • Effects of pegorgotein in neurologic outcome of patients with severe head injury: A multicenter, randomized controlled trial
    • YOUNG, B., RUNGE, S.W., and WAXMAN, K.S. (1996). Effects of pegorgotein in neurologic outcome of patients with severe head injury: a multicenter, randomized controlled trial. J.A.M.A. 276, 538-543.
    • (1996) J.A.M.A. , vol.276 , pp. 538-543
    • Young, B.1    Runge, S.W.2    Waxman, K.S.3
  • 55
    • 0031963829 scopus 로고    scopus 로고
    • Mechanism of brain protection by nitroxide radicals in experimental model of closed-head injury
    • ZHANG, R., SHOHAMI, E., BEIT-YANNAI, E., et al. (1998). Mechanism of brain protection by nitroxide radicals in experimental model of closed-head injury. Free Radic. Biol. Med. 24, 332-340.
    • (1998) Free Radic. Biol. Med. , vol.24 , pp. 332-340
    • Zhang, R.1    Shohami, E.2    Beit-Yannai, E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.