Synthesis and antiproliferative evaluation of amide-containing flavone and isoflavone derivatives

Bioorganic and Medicinal Chemistry

Volumn 16, Issue 16, 2008, Pages 7639-7645

  Chen, I Li ^a   Chen, Jhy Yih ^a   Shieh, Po Chuen ^a   Chen, Jih Jung ^a   Lee, Choa Hsun ^b   Juang, Shin Hun ^b,c   Wang, Tai Chi ^a  

^a TAJEN UNIVERSITY   (Taiwan)

^b CHINA MEDICAL UNIVERSITY   (Taiwan)

^c CHINA MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

Antiproliferative activity; Apoptosis; Cytotoxicity; Flavone; Isoflavone

Indexed keywords

2 (4 OXO 2 PHENYL 4H CHROMEN 3 YLOXY) N PHENYLACETAMIDE; 2 (4 OXO 2 PHENYL 4H CHROMEN 6 YLOXY) N PHENYLACETAMIDE; 2 (4 OXO 2 PHENYL 4H CHROMEN 7 YLOXY) N PHENYLACETAMIDE; 2 (4 OXO 3 PHENYL 4H CHROMEN 7 YLOXY) N PHENYLACETAMIDE; 3 [2 (NAPHTHALEN 2 YL) 2 OXOETHOXY] 2 PHENYL 4H CHROMEN 4 ONE; 6 [2 HYDROXYIMINO 2 (4 FLUOROPHENYL)ETHOXY] 2 PHENYL 4H 1 BENZOPYRAN 4 ONE; 6 [2 HYDROXYIMINO 2 (4 METHOXYPHENYL)ETHOXY] 2 PHENYL 4H 1 BENZOPYRAN 4 ONE; ANTINEOPLASTIC AGENT; APIGENIN; CASTICIN; FLAVONE; GENISTEIN; ISOFLAVONE DERIVATIVE; LUTEOLIN; N (4 FLUOROPHENYL) 2 (4 OXO 2 PHENYL 4H CHROMEN 3 YLOXY)ACETAMIDE; N (4 FLUOROPHENYL) 2 (4 OXO 2 PHENYL 4H CHROMEN 6 YLOXY)ACETAMIDE; N (4 FLUOROPHENYL) 2 (4 OXO 2 PHENYL 4H CHROMEN 7 YLOXY)ACETAMIDE; N (4 FLUOROPHENYL) 2 (4 OXO 3 PHENYL 4H CHROMEN 7 YLOXY)ACETAMIDE; N (4 METHOXYPHENYL) 2 (4 OXO 2 PHENYL 4H CHROMEN 3 YLOXY)ACETAMIDE; N (4 METHOXYPHENYL) 2 (4 OXO 2 PHENYL 4H CHROMEN 6 YLOXY)ACETAMIDE; N (4 METHOXYPHENYL) 2 (4 OXO 2 PHENYL 4H CHROMEN 7 YLOXY)ACETAMIDE; N (BIPHENYL 4 YL) 2 (4 OXO 2 PHENYL 4H CHROMEN 3 YLOXY)ACETAMIDE; N (BIPHENYL 4 YL) 2 (4 OXO 2 PHENYL 4H CHROMEN 6 YLOXY)ACETAMIDE; N (BIPHENYL 4 YL) 2 (4 OXO 2 PHENYL 4H CHROMEN 7 YLOXY)ACETAMIDE; N (NAPHTHALEN 2 YL) 2 (4 OXO 2 PHENYL 4H CHROMEN 3 YLOXY)ACETAMIDE; N (NAPHTHALEN 2 YL) 2 (4 OXO 2 PHENYL 4H CHROMEN 6 YLOXY)ACETAMIDE; N (NAPHTHALEN 2 YL) 2 (4 OXO 2 PHENYL 4H CHROMEN 7 YLOXY)ACETAMIDE; N (NAPHTHALEN 2 YL) 2 (4 OXO 3 PHENYL 4H CHROMEN 7 YLOXY)ACETAMIDE; QUERCETIN; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ALKYLATION; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CELL CYCLE ARREST; CELL CYCLE G0 PHASE; CELL CYCLE G1 PHASE; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CHROMATOPHORE; CONTROLLED STUDY; CYTOTOXICITY; DRUG ACTIVITY; DRUG INHIBITION; DRUG SYNTHESIS; HUMAN; HUMAN CELL; ISOMER; LUNG CARCINOMA; NASOPHARYNX CARCINOMA; STRUCTURE ACTIVITY RELATION;

AMIDES; ANTINEOPLASTIC AGENTS; CELL CYCLE; CELL GROWTH PROCESSES; CELL LINE, TUMOR; HUMANS; ISOFLAVONES; MAGNETIC RESONANCE SPECTROSCOPY; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 49149118126     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2008.07.013     Document Type: Article

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