HIV-1 Tat-mediated protein transduction of human brain creatine kinase into PC12 cells

Journal of Biochemistry and Molecular Biology

Volumn 41, Issue 7, 2008, Pages 537-541

  Min, Seop Jeong ^a   Dae, Won Kim ^a   Min, Jung Lee ^a   Yeom, Pyo Lee ^a   So, Young Kim ^a   Sun, Hwa Lee ^a   Sang, Ho Jang ^a   Kil, Soo Lee ^a   Park, Jinseu ^a   Kang, Tae Cheon ^a   Cho, Sung Woo ^b   Kwon, Oh Shin ^c   Won, Sik Eum ^a   Soo, Young Choi ^a  

^a Hallym University   (South Korea)

^b University of Ulsan College of Medicine   (South Korea)

^c Kyungpook National University   (South Korea)

Author keywords

Epilepsy; HIV 1; Human creatine kinase (CK); Protein therapy; Protein transduction; Tat peptide

Indexed keywords

CREATINE KINASE BB; HYBRID PROTEIN; TRANSACTIVATOR PROTEIN;

ANIMAL; ARTICLE; CELL STRAIN; EVALUATION; GENETIC TRANSDUCTION; GENETICS; HUMAN; ISOLATION AND PURIFICATION; METHODOLOGY; MOLECULAR CLONING; RAT; SYNTHESIS;

ANIMALS; CLONING, MOLECULAR; CREATINE KINASE, BB FORM; HUMANS; PC12 CELLS; RATS; RECOMBINANT FUSION PROTEINS; TAT GENE PRODUCTS, HUMAN IMMUNODEFICIENCY VIRUS; TRANSDUCTION, GENETIC;

ANIMALIA; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 49149089277     PISSN: 12258687     EISSN: 02191024     Source Type: Journal    
DOI: None     Document Type: Article

References (32)

1. Ellington, W. R. (2001) Evolution and physiological roles of phosphagen system. Annu. Revi. Physiol. 63, 289-325.
2. Hoffman, G. G. and Ellington, W. R. (2005) Over-expression, purification and characterization of the oligomerization dynamics of an invertebrate mitochondrial creatine kinase. Biochim. Biophys. Acta 1751, 184-193.
3. Chen, L. H., White, C. B., Babbitt, P. C., McLeish, M. J. and Kenyon, G. L. (2000) A comparative study of human muscle and brain creatine kianse expressed in Escherichia coli. J. Protein Chem. 19, 59-66.
4. Wayy, M. and Kaddurah-Daouk, R. (2000) Creatine and creatine metabolism. Physiol. Rev. 80, 1107-1213.
5. Choi, H., Park, C. S., Kim, B. G., Cho, J. W., Park, J. B., Bae, Y. S. and Bae, D. S. (2001) Creatine kinase B is a target molecule of reactive oxygen species in cervical cancer. Mol. Cells 12, 412-417.
6. Haas, R. C. and Strauss, A. W. (1990) Separate nuclear genes encode sarcomere-specific and ubiquitous human mitochondrial creatine kinase isoenzymes. J. Biol. Chem. 265, 6921-6927.
7. Mariman, E. C., Schepens, J. T. and Wieringa, B. (1989) Complete nucleotide sequence of the human creatine kinase B gene. Nucleic Acids Res. 17, 6385.
8. Perryman, M. B., Kerner, S. A., Bohlmeyer, T. J. and Roberts, R. (1986) Isolation and sequence analysis of a full-length cDNA for human M creatine kinase. Biochem. Biophys. Res. Commun. 140, 981-989.
9. Villareal-Levy, G., Ma, T. S., Kerner, S. A., Roberts, R. and Perryman, M. B. (1987) Human creatine kinase: isolation and sequence analysis of cDNA clones for the B subunit, development of subunit specific probes and determination of gene copy number. Biochem. Biophys. Res. Commun. 144, 1116-1127.
10. Gruemer, H. D. and Prior, T. (1987) Carrier detection in Duchenne muscular dystrophy: a review of current issues and approaches. Clin. Chim. Acta 162, 1-18.
11. Wu, A. H. (1989) Creatine kinase isoforms in ischemic heart disease. Clin. Chem. 35, 7-13.
12. Tomimoto, H., Yamamoto, K., Homburger, H, A. and Yanagihara, T. (1993) Immunoelectron microscopic investigation of creatine kinase BB-isozyme after cerebral ischemia in gerbils. Acta Neuropathol. 86, 447-455.
13. Aksenov, M., Aksenova, M. V., Butterfield, A. D. and Markesbery, W. R. (2000) Oxidative modification of creatine kinase BB in Alzheimer's disease brain. J. Neurochem. 74, 2520-2527.
14. David, S. S., Shoemaker, M. and Haley, B. E. (1998) Abnormal properties of creatine kinasein Alzheimer's brain disease: correlation of reduced enzyme activity and active site photolabelling with aberrant cytosol-membrane partintioning. Mol. Brain Res. 54, 276-287.
15. Delwing, D., Cornelio, A. R., Wajner, M., Wannmacher C. M. D. and Wyse, A. T. S. (2007) Arginine administration reduces creatine kinase activity in rat cerebellum. Metab. Brain Res. 22, 13-23.
16. Wadia, J. and Dowdy, S. F. (2002) Protein transduction technology. Curr. Opin. Biotechnol. 13, 52-56.
17. Morris, M. C., Depollier, J., Mery, J., Heitz, F. and Divita, G. (2001) A peptide carrier for the delivery of biologically active proteins into mammalian cells. Nat. Biotechnol. 19, 1173-1176.
18. Schwarze, S. R., Ho, A., Vocero-Akbani, A. and Dowdy, S. R. (1999) In vivo protein transduction: delivery of a biologically active protein into the mouse. Science 285, 1569-1572.
19. Prochiantz, A. (2000) Messenger proteins: homeoproteins, TAT and others. Curr. Opin. Cell Biol. 12, 400-406.
20. Kwon, H. Y., Eum, W. S., Jang, H. W., Kang, J. H., Ryu, J. Y., Lee, B. R., Jin, L. H., Park, J. and Choi, S. Y. (2000) Transduction of Cu,Zn-superoxide dismutase mediated by an HIV-1 Tat protein basic domain into mammalian cells. FEBS Lett. 485, 163-167.
21. Eum W. S., Choung, I. S., Li, M. Z., Kang, J. H., Kim, D. W., Park, J., Kwon, H. Y. and Choi, S. Y. (2004) HIV-1 Tat mediated protein transduction of Cu,Zn-superoxide dismutase into pancreatic β cells in vitro and in vivo. Free Radic. Biol. Med. 37, 339-349.
22. Choi, H. S., An, J. J., Kim, S. Y., Lee, S. H., Kim, D. W., Yoo, K. Y., Won, M. H., Kang, T. C., Kwon, H. J., Kang, J. H., Cho, S. W., Kwon, O. S., Park, J., Eum, W. S. and Choi, S. Y. (2006) PEP-1-SOD fusion protein efficiently protects against paraquat-induced dopaminergic neuron damage in a Parkinson disease mouse model. Free Radic. Biol. Med. 41, 1058-1068.
23. Eum, W. S., Kim D. W., Hwang, I. K., Yoo, K. Y., Kang, T. C., Jang, S. H., Choi, H. S., Choi, S. H., Kim, Y. H., Kim, S. Y., Kwon, H. Y., Kang, J. H., Kwon, O. S., Cho, S. W., Lee, K. S., Park, J., Won, M. H. and Choi, S. Y. (2004) In vivo protein transduction: biologically active intact PEP-1-superoxide dismutase fusion protein efficiently protects against ischemic insult. Free Radic. Biol. Med. 37, 1656-1669.
24. De Lanerolle, N. C., Kim, J. H., Robbins, R. J. and Spencer, D. D. (1989) Hippocampal interneuron loss and plasticity in human temporal lobe epilepsy. Brain Res. 495, 387-395.
25. Mathern. G. W., Pretorius J. K. and Babb, T. L. (1995) Quantified patterns of mossy fiber sprouting and neurons densities in hippocampal and lesional seizures. J. Neurosurg. 82, 211-219.
26. Wittner, L., Magloczky, Z., Borhegyi, Z., Halasz, P., Toth, S., Eross, L., Szabo, Z. and Freund, T. F. (2001) Preservation of perisomatic inhibitory input of granule cells in the epileptic human dentate gyrus. Neurosci. 108, 587-600.
27. Towler, E. M., Wilson, L. K., Zhou, Y. C., Ma, T. S. and Fisher, R. J. (2000) A complete system for identifying inhibitors of creatine kinase B. Anal. Biochem. 279, 96-99.
28. Richard, J. P., Melikov, K., Vives, E., Rmos, C., Vereure, B., Gait, M. J., Chernomordik, L. V. and Lebleu, B. (2003) Cell penetrating peptides: A reevaluaation of the mechanism of cellular uptake. J. Biol. Chem. 278, 585-590.
29. Cashman, S. M., Morris, D. J., and Kuman-Singh, R. (2003). Evidence of protein transduction but not intracellular by protein fused to HIV Tat in retinal cell culture and in vivo. Mol. Ther. 8, 130-142.
30. Bradford, M. (1976). A rapid and sensitive method for the quantitation of microgram quantities utilizing the principle of protein-dye binding. Anal. Biochem. 72, 248-254.
31. Alterio, J., Courtois, Y., Robelin, J., Bechet, D. and Martelly, I. (1990) Acidic and basic fibroblast growth factor mRNAs are expressed by skeletal muscle satellite cells. Biochem. Biophysic. Res. Commun. 166, 1205-1212.
32. Kang, H. Y., Shim, D., Kang, S. S., Chang, S, I. and Kim, H. Y. (2006) Protein kinase B inhibits endostatin-induced apoptosis in HUVECs. J. Biochem. Mol. Biol. 39, 97-104.