Gas chromatography/electron-capture negative ion mass spectrometry for the quantitative determination of 2- and 3-hydroxy fatty acids in bovine milk fat

Journal of Agricultural and Food Chemistry

Volumn 56, Issue 14, 2008, Pages 5500-5505

  Jenske, Ramona ^a   Vetter, Walter ^a  

^a UNIVERSITY OF HOHENHEIM   (Germany)

Author keywords

hydroxy fatty acids; hydroxy fatty acids; GC ECNI MS SIM; Milk fat; Quantification

Indexed keywords

BENZOIC ACID DERIVATIVE; FAT; FATTY ACID; HYDROXYACID; PENTAFLUOROBENZOYL CHLORIDE;

ANIMAL; ARTICLE; CATTLE; CHEMISTRY; MASS FRAGMENTOGRAPHY; METHODOLOGY; MILK; SENSITIVITY AND SPECIFICITY;

ANIMALS; BENZOATES; CATTLE; FATS; FATTY ACIDS; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; HYDROXY ACIDS; MILK; SENSITIVITY AND SPECIFICITY;

BACTERIA (MICROORGANISMS); BOVINAE;

EID: 49049107725     PISSN: 00218561     EISSN: None     Source Type: Journal    
DOI: 10.1021/jf800647w     Document Type: Article

References (26)

1. Bonn, M.; Heinz, E.; Lüthje, S. Lipid composition and fluidity of plasma membranes isolated from corn (Zea mays L.) roots. Arch. Biochem. Biophys. 2001, 387, 35-40.
2. Smith, C. R.; Wolff, I. A. Characterization of naturally occurring a-hydroxylinolenic acid. Lipids 1969, 4, 9-14.
3. 5 reductase in congenital methemoglobinemia with mental retardation. Lipids 1979, 15, 272-275.
4. Niederer, M.; Bollhalder, R. Identification of species specific central nervous tissue by gas chromatography-mass spectrometry (GC-MS) - a possible method for supervision of meat products and cosmetics. Mitt. Lebensmittelunters. Hyg. 2001, 92, 133-144.
5. Biedermann, W.; Lucker, E.; Hensel, A. Detection of tissues of the central nervous system (CNS) as specified risk material (SRM) in meat products by means of gas chromatography-mass spectrometry (GC-MS). Berl. Muench. Tieraerztl. Wochenschr. 2002, 115, 131-133.
6. Szponar, B.; Norin, E.; Midtvedt, T.; Larsson, L. Limitations in the use of 3-hydroxy fatty acid analysis to determine endotoxin in mammalian samples. J. Microbiol. Methods 2002, 50, 283-289.
7. Mielniczuk, Z.; Alugupalli, S.; Mielniczuk, E.; Larsson, L. Gas chromatography-mass spectrometry of lipopolysaccharide 3-hydroxy fatty acids: comparison of pentafluorobenzoyl and trimethylsilyl methyl ester derivatives. J. Chromatogr. 1992, 623, 115-122.
8. Mielniczuk, Z.; Mielniczuk, E.; Larsson, L. Gas chromatography-mass spectrometry methods for analysis of 2- and 3-hydroxylated fatty acids: application for endotoxin measurements. J. Microbiol. Methods 1993, 17, 91-102.
9. Sonesson, A.; Larsson, L.; Schütz, A.; Hagmar, L.; Hallberg, T. Comparison of the Limulus amebocyte lysate test and gas chromatography-mass spectrometry for measuring lipopolysaccharides (endotoxins) in airborne dust from poultry-processing industries. Appl. Environ. Microbiol. 1990, 56, 1271-1278.
10. Lee, A. K. Y.; Chan, C. K.; Fang, M.; Lau, A. P. S. The 3-hydroxy fatty acids as biomarkers for quantification and characterization of endotoxins and gram-negative bacteria in atmospheric aerosols in Hong Kong. Atmos. Environ. 2004, 38, 6307-6317.
11. Keinänen, M. M.; Korhonen, L. K.; Martikainen, P. J.; Vartiainen, T.; Miettinen, I. T.; Lehtola, M. J.; Nenonen, K.; Pajunen, H.; Kontra, M. H. Gas chromatographic-mass spectrometric detection of 2- and 3-hydroxy fatty acids as methyl esters from soil, sediment and biofilm. J. Chromatogr. B 2003, 783, 443-451.
12. Parks, O. W. Isolation and characterization of nonesterified 3-hydroxy acids in milk. J. Diary Sci. 1977, 60, 718-720.
13. Chance, D. L.; Gerhardt, K. O.; Mawhinney, T. P. Gas-liquid chromatography-mass spectrometry of hydroxyl fatty acids as their methyl ester tert-butyldimethylsilyl ethers. J. Chromatogr. A 1998, 793, 91-98.
14. Özen, H. C.; Bashan, M.; Keskin, C.; Toker, Z. Fatty acid and 3-hydroxy fatty acid composition of two Hypericum species from Turkey. Eur. J. Lipid Sci. Technol. 2004, 106, 68-70.
15. Ferrando, R.; Szponar, B.; Sanchez, A.; Larsson, L.; Valero-Guillen, P. L. 3-Hydroxy fatty acids in saliva as diagnostic markers in chronic periodontitis. J. Microbiol. Methods 2005, 62, 285-291.
16. Wakeham, S. G.; Pease, T. K.; Benner, R. Hydroxy fatty acids in marine dissolved organic matter as indicators of bacterial membrane material. Org. Geochem. 2003, 34, 857-868.
17. Lie Ken Jie, M. C. F.; Choi, Y. C. Mass spectral studies of deuterium-labelled picolinyl fatty esters in the determination of double-bond position. J. Am. Oil Chem. Soc. 1992, 69, 1245-1247.
18. Standard Method of the German Society for Fat Science (DGF) 1998;C-VI 11d.
19. Thurnhofer, S.; Vetter, W. A gas chromatography/electron ionization-mass spectrometry-selected ion monitoring method for determining the fatty acid pattern in food after formation of fatty acid methyl ester. J. Agric. Food Chem. 2005, 53, 8896-8903.
20. Weichbrodt, M.; Vetter, W.; Luckas, B. Microwave-assisted extraction and accelerated solvent extraction with the solvent mixture ethyl acetate/cyclohexane (1:1, v:v) in view of quantitative determination of organochlorines in fish tissue. J. AOAC Int. 2000, 83, 1334-1343.
21. Youhnovski, N.; Schulz, D.; Schwarz, C.; Spiteller, G.; Schubert, K. Determination of hydroxyoctadecadienoic acids. Z. Naturforsch. 2002, 58c, 268-276.
22. Moldovan, Z.; Jover, E.; Bayona, J. M. Gas chromatographic and mass spectrometric methods for the characterisation of long-chain fatty acids - application to wool wax extracts. Anal. Chim. Acta 2002, 465, 359-378.
23. Jenske, R. Vetter, W. Highly selective and sensitive gas chromatography-electron-capture negative-ion mass spectrometry method for the indirect enantioselective identification of 2- and 3-hydroxy fatty acids in food and biological samples. J. Chromatogr A 2007, 1146, 225-231.
24. Wyatt, C. J.; Pereira, R. L.; Day, E. A. The lactone precursor in fresh milk fat: identification of the hydroxy fatty acids Lipids 1966, 2, 208-211.
25. Wyatt, C. J.; Pereira, R. L.; Day, E. A. Lactone precursor in fresh milk fat: Isolation and characterization of the precursor. J. Dairy Sci. 1967, 50, 1760-1763.
26. Dimick, D. S.; Patton, S.; Kinsella, J. E.; Walker, N. J. The prevalence of aliphatic delta-lactones or their precursors in animal fats. Lipids 1966, 1, 387-390.