Effect of curcumin on antioxidant and detoxification mechanisms in the livers of aging rats;Wpływ kurkuminy na detoksykacyjne i antyoksydacyjne mechanizmy w wa̧trobie szczurów podczas starzenia

Medycyna Weterynaryjna

Volumn 64, Issue 7, 2008, Pages 955-957

  Gutowicz, Marzena ^a   Chołojczyk, Małgorzata ^a   Pyrzanowska, Justyna ^b   Widy Tyszkiewicz, Ewa ^b   Barańczyk Kuźma, Anna ^a,c  

^a INSTITUTE OF PSYCHIATRY AND NEUROLOGY   (Poland)

^b MEDICAL UNIVERSITY OF WARSAW   (Poland)

^c NONE   (Poland)

Author keywords

Aging; Curcumin; Detoxification; Liver; Oxidative stress

Indexed keywords

ANIMALIA; CURCUMA LONGA; RATTUS;

EID: 49049107333     PISSN: 00258628     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (16)

1. Bala K., Tripathy B. C., Sharma D.: Neuroprotective and anti-ageing effects of curcumin in aged rat brain regions. Biogerontology 2006, 7, 81-89.
2. Bradford M. M.: A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 1976, 72, 248-254.
3. Chinard F. P.: Photometric estimation of prolin and ornithine. J. Biol. Chem. 1952, 199, 91-95.
4. Devasena T., Rajasekaran K. N., Menon V. P.: Bis-1,7-(2- hydroxyphenyl)-hepta-1,6-diene-3,5-dione (a curcumin analog) ameliorates DMH-induced hepatic oxidative stress during colon carcinogenesis. Pharmacol. Res. 2002, 46, 39-45.
5. Frank N., Knauft J., Amelung F., Nair J., Wesch H., Bartsch H.: No prevention of liver and kidney tumors in Long-Evans Cinnamon rats by dietary curcumin, but inhibition at other sites and of metastases. Mutation Res. 2003, 523-524, 127-135.
6. Goel A., Boland C. R., Chauhan D. P.: Specific inhibition of cyclooxygenase-2 (COX-2) expression by dietary curcumin in HT-29 human colon cancer cells. Cancer Lett. 2001, 172, 111-118.
7. Góth L.: A simple method for determination of serum catalase activity and revision of reference range. Clin. Chim. Acta. 1991, 196, 143-152.
8. Gutowicz M., Sadurska B., Chołojczyk M., Pokorska-Lis M., Siwinska-Ziółkowska A., Barańczyk-Kuźma A.: Antioxidant status in different regions of heroin addicts' brain. Environ. Toxicol. Pharmacol. 2006, 21, 80-85.
9. Habig W. H., Pabst M. J., Jakoby W. B.: Glutathione S-transferases; the first enzymatic step in mercapturic acid formation. J. Biol. Chem. 1974, 249, 7130-7139.
10. Jaruga E., Bielak-Żmijewska A., Sikora E., Skierski J., Radziszewska E., Piwocka K., Bartosz G.: Glutathione-independent Mechanism of Apoptosis Inhibition by Curcumin in Rat Thymocytes. Biochem. Pharmacol. 1998, 56, 961-965.
11. . Kelloff G. J., Crowell J. A., Hawk E. T., Steele V. E., Lubert R. A., Boone C. W., Covey J. M.: Strategy and planning for chemopreventive drug development: Clinical development plans II. J. Cell Biochem. 1996, 26, 54-71.
12. Narayan S.: Curcumin, a multi-functional chemopreventive agent, blocks growth of colon cancer cell by targeting β-catenin-mediated transactivation and cell-cell adhesion pathways. J. Mol. Histol. 2004, 35, 301-307.
13. Okhawa H., Ohishi N., Yagi K.: Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal. Biochem. 1979, 95, 351-358.
14. Piper J. T., Singhal S. S., Salameh M. S., Torman R. T., Awasthi Y. C., Awasthi S.: Mechanisms of anticarcinogenic properties of curcumin on glutathione linked detoxification enzymes in rat liver S. Int. J. Biochem. Cell Biol. 1998, 30, 445-456.
15. Sedlak J., Lindsay R. H.: Estimation of total, protein-bound, and nonprotein sulfhydryl groups in tissue with Ellman's Reagent. Anal. Biochem. 1968, 25, 192-205.
16. Sreepriya M., Bali G.: Effects of administration of Embelin and Curcumin on lipid peroxidation, hepatic glutathione antioxidant defense and hematopoietic system during N-nitrosodiethylamine/Phenobarbital-induced hepatocarcinogenesis in Wistar rats. Mol. Cell. Biochem. 2006, 284, 49-55.