Opportunistic infections in immunologically compromised nonhuman primates

ILAR Journal

Volumn 49, Issue 2, 2008, Pages 191-208

  Wachtman, Lynn M ^a   Mansfield, Keith G ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Immune dysfunction; Immunosuppression; Measles; Opportunistic infections; Simian immunodeficiency virus; Simian type D retrovirus

Indexed keywords

ACANTHAMOEBA; ADENOVIRUS; ANIMAL HEALTH; ANTIBODY RESPONSE; ASPERGILLOSIS; BALAMUTHIA MANDRILLARIS; BETAHERPESVIRINAE; CANDIDA ALBICANS; CD4 LYMPHOCYTE COUNT; CRYPTOCOCCUS NEOFORMANS; CRYPTOSPORIDIUM PARVUM; CYTOMEGALOVIRUS; ENTEROCYTOZOON; ENTEROPATHOGENIC ESCHERICHIA COLI; EPSTEIN BARR VIRUS; GERMFREE ANIMAL; GINGIVITIS; HEPATITIS C VIRUS; HERPES SIMPLEX; HERPES VIRUS; HISTOPLASMA CAPSULATUM; HUMAN HERPESVIRUS 8; IMMUNE DEFICIENCY; INFECTION CONTROL; MEASLES VIRUS; MEDICAL RESEARCH; MYCOBACTERIUM AVIUM; MYCOBACTERIUM INTRACELLULARE AVIUM; MYCOBACTERIUM TUBERCULOSIS; NAEGLERIA FOWLERI; NONHUMAN; OPPORTUNISTIC INFECTION; ORGANISM COLONY; PLASMODIUM; PNEUMOCYSTIS CARINII; PNEUMOCYSTIS JIROVECI; PRIMATE; PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY; QUALITY CONTROL; RETROVIRUS; REVIEW; RHODOCOCCUS EQUI; RISK REDUCTION; SIMIAN IMMUNODEFICIENCY VIRUS; SIMIAN VIRUS 40; TOXOPLASMA GONDII; VIRUS LOAD; ZOONOSIS; ANIMAL; ARTICLE; GROWTH, DEVELOPMENT AND AGING; IMMUNOLOGY; VIROLOGY;

ANIMALIA; HUMAN TYPE D RETROVIRUS; PRIMATES; SIMIAE; SIMIAN IMMUNODEFICIENCY VIRUS; TYPE D RETROVIRUSES;

ANIMALS; IMMUNOCOMPROMISED HOST; OPPORTUNISTIC INFECTIONS; PRIMATES; RETROVIRUSES, SIMIAN; SIMIAN IMMUNODEFICIENCY VIRUS;

EID: 48949120109     PISSN: 10842020     EISSN: None     Source Type: Journal    
DOI: 10.1093/ilar.49.2.191     Document Type: Review

References (185)

1. Adams RJ, Bishop JL. 1980. An oral disease resembling noma in six rhesus monkeys (Macaca mulatta). Lab Anim Sci 30:85-91.
2. Aksozek A, McClellan K, Howard K, Niederkorn JY, Alizadeh H. 2002. Resistance of Acanthamoeba castellanii cysts to physical, chemical, and radiological conditions. J Parasitol 88:621-623.
3. Alford CA, Stagno S, Pass RF, Britt WJ. 1990. Congenital and perinatal cytomegalovirus infections. Rev Infect Dis 12 Suppl 7:S745-S753.
4. Andrade MR, Yee J, Barry P, Spinner A, Roberts JA, Cabello PH, Leite JP, Lerche NW. 2003. Prevalence of antibodies to selected viruses in a long-term closed breeding colony of rhesus macaques (Macaca mulatta) in Brazil. Am J Primatol 59:123-128.
5. Auwaerter PG, Rota PA, Elkins WR, Adams RJ, DeLozier T, Shi Y, Bellini WJ, Murphy BR, Griffin DE. 1999. Measles virus infection in rhesus macaques: Altered immune responses and comparison of the virulence of six different virus strains. J Infect Dis 180:950-958.
6. Axthelm MK, Koralnik IJ, Dang X, Wuthrich C, Rohne D, Stillman IE, Letvin NL. 2004. Meningoencephalitis and demyelination are pathologic manifestations of primary polyomavirus infection in immunosuppressed rhesus monkeys. J Neuropath Exp Neur 63:750-758.
7. Barry PA, Lockridge KM, Salamat S, Tinling SP, Yue Y, Zhou SS, Gospe SM, Britt WJ, Tarantal AF. 2006. Nonhuman primate models of intrauterine cytomegalovirus infection. ILAR J 47:49-64.
8. Baskerville A, Ramsay AD, Millward-Sadler GH, Cook RW, Cranage MP, Greenaway PJ. 1991. Chronic pancreatitis and biliary fibrosis associated with cryptosporidiosis in simian AIDS. J Comp Pathol 105:415-421.
9. Baskin GB. 1987. Disseminated cytomegalovirus infection in immunodeficient rhesus monkeys. Am J Pathol 129:345-352.
10. Baskin GB. 1991. Disseminated histoplasmosis in a SIV-infected rhesus monkey. J Med Primatol 20:251-253.
11. Baskin GB. 1996. Cryptosporidiosis of the conjunctiva in SIV-infected rhesus monkeys. J Parasitol 82:630-632.
12. Baskin GB, Soike KF. 1989. Adenovirus enteritis in SIV-infected rhesus monkeys. J Infect Dis 160:905-907.
13. Baskin GB, Roberts ED, Kuebler D, Martin LN, Blauw B, Heeney J, Zurcher C. 1995. Squamous epithelial proliferative lesions associated with rhesus Epstein-Barr virus in simian immunodeficiency virus-infected rhesus monkeys. J Infect Dis 172:535-539.
14. Baskin GB, Cremer KJ, Levy LS. 2001. Comparative pathobiology of HIV- and SIV-associated lymphoma. AIDS Res Hum Retrov 17:745-751.
15. Benveniste RE, Arthur LO, Tsai C-C, Sowder R, Copeland TD, Henderson LE, Oroszlan S. 1986. Isolation of a lentivirus from a macaque with lymphoma: Comparison with HTLV-III/LAV and other lentiviruses. J Virol 60:483-490.
16. Bergquam EP, Avery NA, Shiigi SM, Axthelm MK, Wong SW. 1999. Rhesus rhadinovirus establishes a latent infection in B lymphocytes in vivo. J Virol 73:7874-7876.
17. Bielefeldt-Ohmann H, Barouch DH, Bakke AM, Bruce AG, Durning M, Grant R, Letvin NL, Ryan JT, Schmidt A, Thouless ME, Rose TM. 2005. Intestinal stromal tumors in a simian immunodeficiency virus-infected, simian retrovirus-2 negative rhesus macaque (Macaca mulatta). Vet Pathol 42:391-396.
18. Board KF, Patil S, Lebedeva I, Capuano S 3rd, Trichel AM, Murphey-Corb M, Rajakumar PA, Flynn JL, Haidaris CG, Norris KA. 2003. Experimental Pneumocystis carinii pneumonia in simian immunodeficiency virus-infected rhesus macaques. J Infect Dis 187:576-588.
19. Boyce JT, Giddens WE Jr, Valerio M. 1978. Simian adenoviral pneumonia. Am J Pathol 91:259-276.
20. Brown KE, Green SW, O'Sullivan MG, Young NS. 1995. Cloning and sequencing of the simian parvovirus genome. Virology 210:314-322.
21. Brown KE, Liu Z, Gallinella G, Wong S, Mills IP, O'Sullivan MG. 2004. Simian parvovirus infection: A potential zoonosis. J Infect Dis 190:1900-1907.
22. Bruce AG, Bakke AM, Thouless ME, Rose TM. 2005. Development of a real-time QPCR assay for the detection of RV2 lineage-specific rhadinoviruses in macaques and baboons. Virology Journal 2:2.
23. Bruce AG, Bakke AM, Bielefeldt-Ohmann H, Ryan JT, Thouless ME, Tsai C-C, Rose TM. 2006. High levels of retroperitoneal fibromatosis (RF)-associated herpesvirus in RF lesions in macaques are associated with ORF73 LANA expression in spindeloid tumor cells. J Gen Virol 87:3529-3538.
24. Buchanan W, Sehgal P, Bronson RT, Rodger RF, Horton JE. 1981. Noma in a nonhuman primate. Oral Surg Oral Med O 52:19-22.
25. Butel JS, Lednicky JA. 1999. Cell and molecular biology of simian virus 40: Implications for human infections and disease. J Natl Cancer Inst 91:119-134.
26. Carter JJ, Madeleine MM, Wipf GC, Garcea RL, Pipkin PA, Minor PD, Galloway DA. 2003. Lack of serologic evidence for prevalent simian virus 40 infection in humans. J Natl Cancer Inst 95:1522-1530.
27. Chalifoux LV, Carville A, Pauley D, Thompson B, Lackner AA, Mansfield KG. 2000. Enterocytozoon bieneusi as a cause of proliferative serositis in simian immunodeficiency virus-infected immunodeficient macaques (Macaca mulatta). Arch Pathol Lab Med 124:1480-1484.
28. Chellman GJ, Lukas VS, Eugui EM, Altera KP, Almquist SJ, Hilliard JK. 1992. Activation of B virus (Herpesvirus simiae) in chronically immunosuppressed cynomolgus monkeys. Lab Anim Sci 42:146-151.
29. Chen PH, Miller GF, Powell DA. 2000. Colitis in a female tamarin (Saguinus mystax). Contemp Top Lab Anim 39:47-49.
30. Chen ZW. 2004. Immunology of AIDS virus and mycobacterial co-infection. Curr HIV Res 2:351-355.
31. Cheung AT, Gardner MB. 1991. Functional deficiency of polymorphonuclear leukocytes in simian acquired immunodeficiency syndrome. Am J Vet Res 52:1523-1526.
32. Cheung TW, Teich SA. 1999. Cytomegalovirus infection in patients with HIV infection. Mt Sinai J Med 66:113-124.
33. Cho Y-G, Ramer J, Rivailler P, Quink C, Garber RL, Beier DR, Wang F. 2001. An Epstein-Barr-related herpesvirus from marmoset lymphomas. Proc Natl Acad Sci U S A 98:1224-1229.
34. Choi YK, Simon MA, Kim DY, Yoon BI, Kwon SW, Lee KW, Seo IB, Kim DY. 1999. Fatal measles virus infection in Japanese macaques (Macaca fuscata). Vet Pathol 36:594-600.
35. Chrétien F, Boche D, Lorin de la Grandmaison G, Ereau T, Mikol J, Hurtrel M, Hurtrel B, Gray F. 2000. Progressive multifocal leukoencephalopathy and oligodendroglioma in a monkey co-infected by simian immunodeficiency virus and simian virus 40. Acta Neuropathol (Berl) 100:332-336.
36. Daniel MD, Letvin NL, King NW, Kannagi M, Seghal PK, Hunt RD, Kanki P, Essex M, Desrosiers RC. 1985. Isolation of a T cell tropic HTLV-III-like retrovirus from macaques. Science 228:1201-1204.
37. Demanche C, Berthelemy M, Petit T, Polack B, Wakefield AE, Dei-Cas E, Guillot J. 2001. Phylogeny of Pneumocystis carinii from 18 primate species confirms host specificity and suggests coevolution. J Clin Microbiol 39:2126-2133.
38. Demanche C, Wanert F, Barthelemy M, Mathieu J, Durand-Joly I, Dei-Cas E, Chermette R, Guillot J. 2005. Molecular and serological evidence of Pneumocystis circulation in a social organization of healthy macaques (Macaca fascicularis). Microbiology 151(Pt 9):3117-3125.
39. Dengjel B, Zahler M, Hermanns W, Heinritzi K, Spillmann T, Thomschke A, Loscher T, Gothe R, Rinder H. 2001. Zoonotic potential of Enterocytozoon bieneusi. J Clin Microbiol 39:4495-4499.
40. Denis M. 1994a. Envelope glycoprotein (gp120) from HIV-1 enhances Mycobacterium avium growth in human bronchoalveolar macrophages: An effect mediated by enhanced prostaglandin synthesis. Clin Exp Immunol 98:123-127.
41. Denis M. 1994b. Tat protein from HIV-1 binds to Mycobacterium avium via a bacterial integrin: Effects on extracellular and intracellular growth. J Immunol 153:2072-2081.
42. Desrosiers RC, Sasseville VG, Czajak SC, Zhang X, Mansfield KG, Kaur A, Johnson RP, Lackner AA, Jung JU. 1997. A herpesvirus of rhesus monkeys related to the human Kaposi's sarcoma-associated herpesvirus. J Virol 71:9764-9769.
43. Donovan JC, Stokes WS, Montrey RD, Rozmiarek H. 1983. Hematologic characterization of naturally occurring malaria (Plasmodium inui) in cynomolgus monkeys (Macaca fascicularis). Lab Anim Sci 33:86-89.
44. Drosten C, Laabs J, Kuhn EM, Schottelius J. 2005. Interspecies transmission of Enterozytozoon bieneusi supported by observations in laboratory animals and phylogeny. Med Microbiol Immunol 194:207-209.
45. Duarte AM, Porto MA, Curado I, Malafronte RS, Hoffmann EH, de Oliveira SG, da Silva AM, Kloetzel JK, Gomes Ade C. 2006. Widespread occurrence of antibodies against circumsporozoite protein and against blood forms of Plasmodium vivax, P. falciparum and P. malariae in Brazilian wild monkeys. J Med Primatol 35:87-96.
46. Eizuru Y, Tsuchiya K, Mori R, Minamishima Y. 1989. Immunological and molecular comparison of simian cytomegaloviruses isolated from African green monkey (Cercopithecus aethiops) and Japanese macaque (Macaca fuscata). Arch Virol 107:65-75.
47. Elkington R, Shoukry NH, Walker S, Crough T, Fazou C, Kaur A, Walker CM, Khanna R. 2004. Cross-reactive recognition of human and primate cytomegalovirus sequences by human CD4 cytotoxic T lymphocytes specific for glycoprotein B and H. Eur J Immunol 34:3216-3226.
48. Epiphanio S, Guimaraes MA, Fedullo DL, Correa SH, Catão-Dias JL. 2000. Toxoplasmosis in golden-headed lion tamarins (Leontopithecus chrysomelas) and emperor marmosets (Saguinus imperator) in captivity. J Zoo Wildl Med 31:231-235.
49. Epiphanio S, Sinhorini IL, Catão-Dias JL. 2003. Pathology of toxoplasmosis in captive New World primates. J Comp Pathol 129:196-204.
50. Feuchtinger T, Lucke J, Hamprecht K, Richard C, Handgretinger R, Schumm M, Greil J, Bock T, Niethammer D, Lang P. 2005. Detection of adenovirus-specific T cells in children with adenovirus infection after allogeneic stem cell transplantation. Br J Haematol 128:503-509.
51. Fiorello CV, Heard DJ, Heller HL, Russell K. 2006. Medical management of Toxoplasma meningitis in a white-throated capuchin (Cebus capucinus). J Zoo Wildl Med 37:409-412.
52. Fogg MH, Kaur A, Cho Y-G, Wang F. 2005. The CD8+ T cell response to an Epstein-Barr virus-related Gammaherpesvirus infecting rhesus macaques provides evidence for immune evasion by the EBNA-1 homologue. J Virol 79:12681-12691.
53. Fogg MH, Garry D, Awad A, Wang F, Kaur A. 2006. The BZLF1 homolog of an Epstein-Barr-related γ-Herpesvirus is a frequent target of the CTL response in persistently infected rhesus macaques. J Immunol 176:3391-3401.
54. Foresman L, Narayan O, Pinson D. 1999. Progressive anemia in a pig-tail macaque with AIDS. Contemp Top Lab Anim Sci 38:20-22.
55. Fortgang IS, Srivastav SK, Baskin GB, Schumacher PM, Levy LS. 2004. Retrospective analysis of clinical and laboratory factors associated with lymphoma in simian AIDS. Leuk Lymphoma 45:161-169.
56. Fultz PN, McClure HM, Anderson DC, Swenson RB, Anand R, Srinivasan A. 1986. Isolation of a T lymphotropic retrovirus from naturally infected sooty mangaby monkeys (Cercocebus atys). Proc Natl Acad Sci U S A 83:5286-5290.
57. Furuta T, Fujita M, Mukai R, Sakakibara I, Sata T, Miki K, Hayami M, Kojima S, Yoshikawa Y. 1993. Severe pulmonary pneumocystosis in simian acquired immunodeficiency syndrome induced by simian immunodeficiency virus: Its characterization by the polymerase-chain-reaction method and failure of experimental transmission to immunodeficient animals. Parasitol Res 79:624-628.
58. Gardner SD, Field AM, Coleman DV, Hulme B. 1971. New human papovavirus (B.K.) isolated from urine after renal transplantation. Lancet 1:1253-1257.
59. Ghassemi M, Andersen BR, Reddy VM, Gangadharam PR, Spear GT, Novak RM. 1995. Human immunodeficiency virus and Mycobacterium avium complex coinfection of monocytoid cells results in reciprocal enhancement of multiplication. J Infect Dis 171:68-73.
60. Gigliotti F, Harmsen AG, Haidaris CG, Haidaris PJ. 1993. Pneumocystis carinii is not universally transmissible between mammalian species. Infect Immun 61:2886-2890.
61. Goodwin BT, Jerome CP, Bullock BC. 1988. Unusual lesion morphology and skin test reaction for Mycobacterium avium complex in macaques. Lab Anim Sci 38:20-24.
62. Green SW, Malkovska I, O'Sullivan MG, Brown KE. 2000. Rhesus and pig-tailed macaque parvoviruses: Identification of two new members of the erythrovirus genus in monkeys. Virology 269:105-112.
63. Guzman RE, Kerlin RL, Zimmerman TE. 1999. Histologic lesions in cynomolgus monkeys (Macaca fascicularis) naturally infected with simian retrovirus type D: Comparison of seropositive, virus-positive, and uninfected animals. Toxicol Pathol 27:672-677.
64. Gyimesi ZS, Lappin MR, Dubey JP. 2006. Application of assays for the diagnosis of toxoplasmosis in a colony of woolly monkeys (Lagothrix lagotricha). J Zoo Wildl Med 37:276-280.
65. Haustein SV, Kolterman AJ, Sundblad JJ, Fechner JH, Knechtle SJ. 2007. Nonhuman primate infections after organ transplantation. ILAR J 49:209-219.
66. Hendricks EE, Lin KC, Boisvert K, Pauley D, Mansfield KG. 2004a. Alterations in expression of monocyte chemotactic protein-1 in the simian immunodeficiency virus model of disseminated Mycobacterium avium complex. J Infect Dis 189:1714-1720.
67. Hendricks EE, Ludlage E, Bussell S, George K, Wegner FH, Mansfield KG. 2004b. Wasting syndrome and disruption of the somatotropic axis in simian immunodeficiency virus-infected macaques with Mycobacterium avium complex infection. J Infect Dis 190:2187-2194.
68. Hendricks Hutto E, Anderson DC, Mansfield KG. 2004. Cytomegalovirus- associated discrete gastrointestinal masses in macaques infected with the simian immunodeficiency virus. Vet Pathol 41:691-695.
69. Henrickson RV, Maul DH, Osborn KG, Sever JL, Madden DL, Ellingsworth LR, Anderson JH, Lowenstine LJ, Gardner MB. 1983. Epidemic of acquired immunodeficiency in rhesus monkeys. Lancet 1:388-390.
70. Hirsch VM, Lifson JD. 2000. Simian immunodeficiency virus infection of monkeys as a model system for the study of AIDS pathogenesis, treatment, and prevention. Adv Pharmacol 49:437-477.
71. Hirsch VM, Dapolito G, Johnson PR, Elkins WR, London WT, Montali RJ, Goldstein S, Brown C. 1995. Induction of AIDS by simian immunodeficiency virus from an African green monkey: Species-specific variation in pathogenicity correlates with extent of in vivo replication. J Virol 69:955-967.
72. Hirsch VM, Santra S, Goldstein S, Plishka R, Buckler-White A, Seth A, Ourmanov I, Brown CR, Engle R, Montefiori D, Glowczwskie J, Kunstman K, Wolinsky S, Letvin NL. 2004. Immune failure in the absence of profound CD4+ T lymphocyte depletion in simian immunodeficiency virus-infected rapid progressor macaques. J Virol 78:275-284.
73. Hoffmann C, Ernst M, Meyer P, Wolf E, Rosenkranz T, Plettenberg A, Stoehr A, Horst HA, Marienfeld K, Lange C. 2007. Evolving characteristics of toxoplasmosis in patients infected with human immunodeficiency virus-1: Clinical course and Toxoplasma gondii-specific immune responses. Clin Microbiol Infect 13:510-515.
74. Holmberg CA, Gribble DH, Takemoto KK, Howley PM, Espana C, Osburn BI. 1977. Isolation of simian virus 40 from rhesus monkeys (Macaca mulatta) with spontaneous progressive multifocal leukoencephalopathy. J Infect Dis 136:593-596.
75. Horvath CJ, Simon MA, Bergsagel DJ, Pauley DR, King NW, Garcea RL, Ringler DJ. 1992. Simian virus 40-induced disease in rhesus monkeys with simian acquired immunodeficiency syndrome. Am J Pathol 140:1431-1440.
76. Huff JL, Eberle R, Capitanio J, Zhou SS, Barry PA. 2003. Differential detection of B virus and rhesus cytomegalovirus in rhesus macaques. J Gen Virol 84(Pt 1):83-92.
77. Ilyinskii PO, Daniel MD, Horvath CJ, Desrosiers RC. 1992. Genetic analysis of simian virus 40 from brains and kidneys of macaque monkeys. J Virol 66:6353-6360.
78. Ishida T, Yamamoto K. 1987. Survey of nonhuman primates for antibodies reactive with Epstein-Barr virus (EBV) antigens and susceptibility of their lymphocytes for immortalization with EBV. J Med Primatol 16:359-371.
79. Johannessen I, Crawford DH. 1999. In vivo models for Epstein-Barr virus (EBV)-associated B cell lymphoproliferative disease. Rev Med Virol 9:263-277.
80. Jonker M, Ringers J, Kuhn EM, 't Hart B, Foulkes R. 2004. Treatment with anti-MHC-class-II antibody postpones kidney allograft rejection in primates but increases the risk of CMV activation. Am J Transplant 4:1756-1761.
81. Kaup FJ, Kuhn EM, Makoschey B, Hunsmann G. 1994. Cryptosporidiosis of liver and pancreas in rhesus monkeys with experimental SIV infection. J Med Primatol 23:304-308.
82. Kaur A, Daniel MD, Hempel D, Lee-Parritz D, Hirsch MS, Johnson RP. 1996. Cytotoxic T lymphocyte responses to cytomegalovirus in normal and simian immunodeficiency virus-infected rhesus macaques. J Virol 70:7725-7733.
83. Kaur A, Hale CL, Noren B, Kassis N, Simon MA, Johnson RP. 2002. Decreased frequency of cytomegalovirus (CMV)-specific CD4+ T lymphocytes in simian immunodeficiency virus-infected rhesus macaques: Inverse relationship with CMV viremia. J Virol 76:3646-3658.
84. Kerdiles YM, Sellin CI, Druelle J, Horvat B. 2006. Immunosuppression caused by measles virus: Role of viral proteins. Rev Med Virol 16:49-63.
85. King JC Jr. 1997. Community respiratory viruses in individuals with human immunodeficiency virus infection. Am J Med 102:19-24; discussion 25-26.
86. King NW, Hunt RD, Letvin NL. 1983. Histopathologic changes in macaques with an acquired immunodeficiency syndrome (AIDS). Am J Pathol 113:382-388.
87. Klotman ME, Henry SC, Greene RC, Brazy PC, Klotman PE, Hamilton JD. 1990. Detection of mouse cytomegalovirus nucleic acid in latently infected mice by in vitro enzymatic amplification. J Infect Dis 161:220-225.
88. Kutok JL, Klumpp S, Simon MA, MacKey JJ, Nguyen V, Middeldorp JM, Aster JC, Wang F. 2004. Molecular evidence for rhesus Lymphocryptovirus infection of epithelial cells in immunosuppressed rhesus macaques. J Virol 78:3455-3461.
89. Lacoste V, Mauclere P, Dubreuil G, Lewis J, Georges-Courbot MC, Gessain A. 2000. KSHV-like herpesviruses in chimps and gorillas. Nature 407:151-152.
90. Lange CG, Lederman MM. 2003. Immune reconstitution with antiretroviral therapies in chronic HIV-1 infection. J Antimicrob Chemoth 51:1-4.
91. Lange CG, Valdez H, Medvik K, Asaad R, Lederman MM. 2002. CD4+ T lymphocyte nadir and the effect of highly active antiretroviral therapy on phenotypic and functional immune restoration in HIV-1 infection. Clin Immunol 102:154-161.
92. Lerche NW, Yee JL, Jennings MB. 1994. Establishing specific retrovirus-free breeding colonies of macaques: An approach to primary screening and surveillance. Lab Anim Sci 44:217-221.
93. Letvin NL, King NW. 1990. Immunologic and pathologic manifestations of the infection of rhesus monkeys with simian immunodeficiency virus of macaques. JAIDS 3:1023-1040.
94. Letvin NL, Daniel MD, Seghal PK, Desrosiers RC, Hunt RD, Waldron LM, MacKey JJ, Schmidt DK, Chalifoux LV, King NW. 1985. Induction of AIDS-like disease in macaque monkeys with T cell tropic retrovirus STLV-III. Science 230:71-73.
95. Levy BM, Mirkovic RR. 1971. An epizootic of measles in a marmoset colony. Lab Anim Sci 21:33-39.
96. Lorenz D, Albrecht P. 1980. Susceptibility of tamarins (Saguinus) to measles virus. Lab Anim Sci 30(4 Pt 1):661-665.
97. Lu Y, Salvato M, Pauza CD, Li J, Sodroski J, Mason K, Wyand M, Letvin NL, Jenkins S, Touzjian N, Chutkowski C, Kushner N, LeFaile M, Payne LG, Roberts B. 1996. Utility of SHIV for testing HIV-1 vaccine candidates in macaques. JAIDS 12:99-106.
98. Mansfield KG. 2005. Development of specific pathogen free nonhuman primate colonies. In: Wolfe-Coote S, ed. The Laboratory Primate. London: Elsevier Academic Press. p 229-239.
99. Mansfield KG, Lackner AA. 1997. Simian immunodeficiency virus-inoculated macaques acquire Mycobacterium avium from potable water during AIDS. J Infect Dis 175:184-187.
100. Mansfield KG, Pauley D, Young HL, Lackner AA. 1995. Mycobacterium avium complex in macaques with AIDS is associated with a specific strain of simian immunodeficiency virus and prolonged survival after primary infection. J Infect Dis 172:1149-1152.
101. Mansfield KG, Carville A, Shvetz D, MacKey J, Tzipori S, Lackner AA. 1997. Identification of an Enterocytozoon bieneusi-like microsporidian parasite in simian-immunodeficiency-virus-inoculated macaques with hepatobiliary disease. Am J Pathol 150:1395-1405.
102. Mansfield KG, Carville A, Hebert D, Chalifoux L, Shvetz D, Lin KC, Tzipori S, Lackner AA. 1998. Localization of persistent Enterocytozoon bieneusi infection in normal rhesus macaques (Macaca mulatta) to the hepatobiliary tree. J Clin Microbiol 36:2336-2338.
103. Mansfield KG, Westmoreland SV, DeBakker CD, Czajak S, Lackner AA, Desrosiers RC. 1999. Experimental infection of rhesus and pig-tailed macaques with macaque rhadinoviruses. J Virol 73:10320-10328.
104. Mansfield KG, Lin KC, Newman J, Schauer D, MacKey J, Lackner AA, Carville A. 2001a. Identification of enteropathogenic Escherichia coli in simian immunodeficiency virus-infected infant and adult rhesus macaques. J Clin Microbiol 39:971-976.
105. Mansfield KG, Lin KC, Xia D, Newman JV, Schauer DB, MacKey J, Lackner AA, Carville A. 2001b. Enteropathogenic Escherichia coli and ulcerative colitis in cotton-top tamarins (Saguinus oedipus). J Infect Dis 184:803-807.
106. Martin BJ, Dysko RC, Chrisp CE. 1991. Pancreatitis associated with simian adenovirus 23 in a rhesus monkey. Lab Anim Sci 41:382-384.
107. Maslow JN, Brar I, Smith G, Newman GW, Mehta R, Thornton C, Didier P. 2003. Latent infection as a source of disseminated disease caused by organisms of the Mycobacterium avium complex in simian immunodeficiency virus-infected rhesus macaques. J Infect Dis 187:1748-1755.
108. Maul DH, Miller CH, Marx PA, Bleviss ML, Madden DL, Henrickson RV, Gardner MB. 1985. Immune defects in simian acquired immunodeficiency syndrome. Vet Immunol Immunop 8:201-214.
109. Maul DH, Lerche NW, Osborn KG, Marx PA, Zaiss C, Spinner A, Kluge JD, MacKenzie MR, Lowenstine LJ, Bryant ML, Blakeslee JR, Henrickson RV, Gardner MB. 1986. Pathogenesis of simian AIDS in rhesus macaques inoculated with the SRV-1 strain of type D retrovirus. Am J Vet Res 47:863-868.
110. Maul DH, Zaiss CP, Mackenzie MR, Shigi SM, Marx PA, Gardner MB. 1988. Simian retrovirus D serogroup 1 has a broad cellular tropism for lymphoid and nonlymphoid cells. J Virol 62:1768-1773.
111. McChesney MB, Fujinami RS, Lerche NW, Marx PA, Oldstone MB. 1989. Virus-induced immunosuppression: Infection of peripheral blood mononuclear cells and suppression of immunoglobulin synthesis during natural measles virus infection of rhesus monkeys. J Infect Dis 159:757-760.
112. McCune JM. 2001. The dynamics of CD4+ T cell depletion in HIV disease. Nature 410:974-979.
113. Miller RA, Bronsdon MA, Kuller L, Morton WR. 1990a. Clinical and parasitologic aspects of cryptosporidiosis in nonhuman primates. Lab Anim Sci 40:42-46.
114. Miller RA, Bronsdon MA, Morton WR. 1990b. Experimental cryptosporidiosis in a primate model. J Infect Dis 161:312-315.
115. Minor P, Pipkin PA, Cutler K, Dunn G. 2003. Natural infection and transmission of SV40. Virology 314:403-409.
116. Mitsunga F, Nakamura S, Hayashi T, Eberle R. 2007. Changes in the titer of anti-B virus antibody in captive macaques (Macaca fuscata, M. mulatta, M. fascicularis). Comp Med 57:120-124.
117. Moghaddam A, Rosenzweig M, Lee-Parritz D, Annis B, Johnson RP, Wang F. 1997. An animal model for acute and persistent Epstein-Barr virus infection. Science 276:2030-2033.
118. Morton WR, Agy MB, Capuano SV, Grant RF. 2007. Specific pathogen-free macaques: Definition, history, and current production. ILAR J 49:137-144.
119. Mueller NJ, Barth RN, Yamamoto S, Kitamura H, Patience C, Yamada K, Cooper DK, Sachs DH, Kaur A, Fishman JA. 2002. Activation of cytomegalovirus in pig-to-primate organ xenotransplantation. J Virol 76:4734-4740.
120. Murphey-Corb M, Martin LN, Rangan SRS, Baskin GB, Gormus BJ, Wolf RH, Andes WA, West M, Montelaro RC. 1986. Isolation of an STLV-III-related retrovirus from macaques with simian AIDS and its possible origin in asymptomatic mangabys. Nature 321:435-437.
121. Norris KA, Wildschutte H, Franko J, Board KF. 2003. Genetic variation at the mitochondrial large-subunit rRNA locus of Pneumocystis isolates from simian immunodeficiency virus-infected rhesus macaques. Clin Diagn Lab Immunol 10:1037-1042.
122. Ochs HD, Morton WR, Tsai CC, Thouless ME, Zhu Q, Kuller LD, Wu YP, Benveniste RE. 1991. Maternal-fetal transmission of SIV in macaques: Disseminated adenovirus infection in an offspring with congenital SIV infection. J Med Primatol 20:193-200.
123. Okada H, Kobune F, Sato TA, Kohama T, Takeuchi Y, Abe T, Takayama N, Tsuchiya T, Tashiro M. 2000. Extensive lymphopenia due to apoptosis of uninfected lymphocytes in acute measles patients. Arch Virol 145:905-920.
124. Osborn KG, Prahalada S, Lowenstine LJ, Gardner MB, Maul DH, Henrickson RV. 1984. The pathology of an epizootic of acquired immunodeficiency in rhesus macaques. Am J Pathol 114:94-103.
125. O'Sullivan MG, Anderson DC, Fikes JD, Bain FT, Carlson CS, Green SW, Young NS, Brown KE. 1994. Identification of a novel simian parvovirus in cynomolgus monkeys with severe anemia: A paradigm of human B19 parvovirus infection. J Clin Invest 93:1571-1576.
126. Pal M, Dube GD, Mehrotra BS. 1984. Pulmonary cryptococcosis in a rhesus monkey (Macaca mulatta). Mykosen 27:309-312.
127. Pereyra F, Rubin RH. 2004. Prevention and treatment of cytomegalovirus infection in solid organ transplant recipients. Curr Opin Infect Dis 17:357-361.
128. Picker LJ. 2006. Immunopathogenesis of acute AIDS virus infection. Curr Opin Immunol 18:399-405.
129. Rangan SRS, Chaiban J. 1980. Isolation and characterization of a cytomegalovirus from the salivary gland of a squirrel monkey (Saimiri sciureus). Lab Anim Sci 30:532-540.
130. Rivailler P, Jiang H, Cho Y-G, Quink C, Wang F. 2002. Complete nucleotide sequence of the rhesus lymphocryptovirus: Genetic validation for an Epstein-Barr virus animal model. J Virol 76:421-426.
131. Rivailler P, Carville A, Kaur A, Rao P, Quink C, Kutok JL, Westmoreland SV, Klumpp S, Simon MA, Aster JC, Wang F. 2004. Experimental rhesus lymphocryptovirus infection in immunosuppressed macaques: An animal model for Epstein-Barr virus pathogenesis in the immunosuppressed host. Blood 104:1482-1489.
132. Roberts JA, Andrews K. 2008. Nonhuman primate quarantine: Its evolution and practice. ILAR J 49:145-156.
133. Robertson LJ, Campbell AT, Smith HV. 1992. Survival of Cryptosporidium parvum oocysts under various environmental pressures. Appl Environ Microbiol 58:3494-3500.
134. Rooney CM, Smith CA, Ng CY, Loftin SK, Sixbey JW, Gan Y, Srivastava DK, Bowman LC, Krance RA, Brenner MK, Heslop HE. 1998. Infusion of cytotoxic T cells for the prevention and treatment of Epstein-Barr virus-induced lymphoma in allogeneic transplant recipients. Blood 92:1549-1555.
135. Rose JB, Huffman DE, Gennaccaro A. 2002. Risk and control of waterborne cryptosporidiosis. FEMS Microbiol Rev 26:113-123.
136. Rose TM, Strand KB, Schultz ER, Schaeffer G, Rankin GW, Thouless ME, Tsai C-C, Bosch ML. 1997. Identification of two homologs of the Kaposi's sarcoma-associated herpesvirus (human herpesvirus 8) in retroperitoneal fibromatosis of different macaque species. J Virol 71:4138-4144.
137. Sasseville VG, Pauley DR, MacKey JJ, Simon MA. 1995. Concurrent central nervous system toxoplasmosis and simian immunodeficiency virus-induced AIDS encephalomyelitis in a Barbary macaque (Macaca sylvana). Vet Pathol 32:81-83.
138. Schiodt M, Lackner A, Armitage G, Lerche N, Greenspan JS, Lowenstine L. 1988. Oral lesions in rhesus monkeys associated with infection by simian AIDS retrovirus, serotype-I (SRV-1). Oral Surg Oral Med O 65:50-55.
139. Schofield LD, Bennett BT, Collins WE, Beluhan FZ. 1985. An outbreak of Plasmodium inui malaria in a colony of diabetic rhesus monkeys. Lab Anim Sci 35:167-168.
140. Schroder C, Pfeiffer S, Wu G, Azimzadeh AM, Aber A, Pierson RN 3rd, O'Sullivan MG. 2006. Simian parvovirus infection in cynomolgus monkey heart transplant recipients causes death related to severe anemia. Transplantation 81:1165-1170.
141. Schultz ER, Rankin GW, Blanc M-P, Raden BW, Tsai C-C, Rose TM. 2000. Characterization of two divergent lineages of macaque rhadinoviruses related to Kaposi's sarcoma-associated herpesvirus. J Virol 74:4919-4928.
142. Schuster FL, Visvesvara GS. 2004. Free-living amoebae as opportunistic and nonopportunistic pathogens of humans and animals. Int J Parasitol 34:1001-1027.
143. Seibold HR, Wolf RH. 1971. Toxoplasmosis in Aotus trivirgatus and Callicebus moloch. Lab Anim Sci 21:118-120.
144. Sequar G, Britt WJ, Lakeman FD, Lockridge KM, Tarara RP, Canfield DR, Zhou SS, Gardner MB, Barry PA. 2002. Experimental coinfection of rhesus macaques with rhesus cytomegalovirus and simian immunodeficiency virus: Pathogenesis. J Virol 76:7661-7671.
145. Sestak K, Aye PP, Buckholt M, Mansfield KG, Lackner AA, Tzipori S. 2003. Quantitative evaluation of Enterocytozoon bieneusi infection in simian immunodeficiency virus-infected rhesus monkeys. J Med Primatol 32:74-81.
146. Sheffield WD, Strandberg JD, Braun L, Shah K, Kalter SS. 1980. Simian virus 40-associated fatal interstitial pneumonia and renal tubular necrosis in a rhesus monkey. J Infect Dis 142:618-622.
147. Shen Y, Zhou D, Chalifoux L, Shen L, Simon M, Zeng X, Lai X, Li Y, Sehgal P, Letvin NL, Chen ZW. 2002. Induction of an AIDS virus-related tuberculosis-like disease in macaques: A model of simian immunodeficiency virus-mycobacterium coinfection. Infect Immun 70:869-877.
148. Shiratsuchi H, Johnson JL, Toossi Z, Ellner JJ. 1994. Modulation of the effector function of human monocytes for Mycobacterium avium by human immunodeficiency virus-1 envelope glycoprotein gp120. J Clin Invest 93:885-891.
149. Simon MA, Chalifoux LV, Ringler DJ. 1992. Pathologic features of SIV-induced disease and the association of macrophage infection with disease evolution. AIDS Res Hum Retrov 8:327-337.
150. Simon MA, Daniel MD, Lee-Parritz D, King NW, Ringler DJ. 1993. Disseminated B virus infection in a cynomolgus monkey. Lab Anim Sci 43:545-550.
151. Simon MA, Ilyinskii PO, Baskin GB, Knight HY, Pauley DR, Lackner AA. 1999. Association of simian virus 40 with a central nervous system lesion distinct from progressive multifocal leukoencephalopathy in macaques with AIDS. Am J Pathol 154:437-446.
152. Sinclair J, Sissons P. 2006. Latency and reactivation of human cytomegalovirus. J Gen Virol 87:1763-1779.
153. Singh B, Kim Sung L, Matusop A, Radhakrishnan A, Shamsul SS, Cox-Singh J, Thomas A, Conway DJ. 2004. A large focus of naturally acquired Plasmodium knowlesi infections in human beings. Lancet 363:1017-1024.
154. Singh I, Sheoran AS, Zhang Q, Carville A, Tzipori S. 2005. Sensitivity and specificity of a monoclonal antibody-based fluorescence assay for detecting Enterocytozoon bieneusi spores in feces of simian immunodeficiency virus-infected macaques. Clin Diagn Lab Immunol 12:1141-1144.
155. Singh I, Li W, Woods M, Carville A, Tzipori S. 2006. Factors contributing to spontaneous Enterocytozoon bieneusi infection in simian immunodeficiency virus-infected macaques. J Med Primatol 35:352-360.
156. Staley EC, Southers JL, Thoen CO, Easley SP. 1995. Evaluation of tuberculin testing and measles prophylaxis procedures used in rhesus macaque quarantine/conditioning protocols. Lab Anim Sci 45:125-130.
157. Stokes WS, Donovan JC, Montrey RD, Thompson WL, Wannemacher RW Jr, Rozmiarek H. 1983. Acute clinical malaria (Plasmodium inui) in a cynomolgus monkey (Macaca fascicularis). Lab Anim Sci 33:81-85.
158. Strayer DS, Pomerantz RJ, Yu M, Rosenzweig M, BouHamdan M, Yurasov S, Johnson RP, Goldstein H. 2000. Efficient gene transfer to hematopoietic progenitor cells using SV40-derived vectors. Gene Ther 7:886-895.
159. Strickler HD, Rosenberg PS, Devesa SS, Hertel J, Fraumeni JF Jr, Goedert JJ. 1998. Contamination of poliovirus vaccines with simian virus 40 (1955-1963) and subsequent cancer rates. JAMA 279:292-295.
160. Stringer JR, Beard CB, Miller RF, Wakefield AE. 2002. A new name (Pneumocystis jiroveci) for Pneumocystis from humans. Emerg Infect Dis 8:891-896.
161. Stuker G, Oshiro LS, Schmidt NJ, Holmberg CA, Anderson JH, Glaser CA, Henrickson RV. 1979. Virus detection in monkeys with diarrhea: The association of adenoviruses with diarrhea and the possible role of rotaviruses. Lab Anim Sci 29:610-616.
162. Stump DS, VandeWoude S. 2007. Animal models for HIV AIDS: A comparative review. Comp Med 57:33-43.
163. van Kuyk RW, Acevedo RA, Torres JV, Levy NB, Planelles V, Munn RJ, Unger RE, Gardner MB, Luciw PA. 1991. Characterization of rhesus macaque B-lymphoblastoid cell lines infected with simian type D retrovirus. AIDS Res Hum Retrov 7:899-909.
164. Vilchez RA, Butel JS. 2004. Emergent human pathogen simian virus 40 and its role in cancer. Clin Microbiol Rev 17:495-508.
165. Visvesvara GS, Moura H, Schuster FL. 2007. Pathogenic and opportunistic free-living amoebae: Acanthamoeba spp., Balamuthia mandrillaris, Naegleria fowleri, and Sappinia diploidea. FEMS Immunol Med Microbiol 50:1-26.
166. Vogel P, Miller CJ, Lowenstine LL, Lackner AA. 1993. Evidence of horizontal transmission of Pneumocystis carinii pneumonia in simian immunodeficiency virus-infected rhesus macaques. J Infect Dis 168:836-843.
167. Vogel P, Weigler BJ, Kerr H, Hendrickx AG, Barry PA. 1994. Seroepidemiologic studies of cytomegalovirus infection in a breeding population of rhesus macaques. Lab Anim Sci 44:25-30.
168. Volney B, Pouliquen JF, de Thoisy B, Fandeur T. 2002. A seroepidemiological study of malaria in human and monkey populations in French Guiana. Acta Trop 82:11-23.
169. von Reyn CF, Maslow JN, Barber TW, Falkinham JO 3rd, Arbeit RD. 1994. Persistent colonisation of potable water as a source of Mycobacterium avium infection in AIDS. Lancet 343:1137-1141.
170. Walls T, Shankar AG, Shingadia D. 2003. Adenovirus: An increasingly important pathogen in paediatric bone marrow transplant patients. Lancet Infect Dis 3:79-86.
171. Weber DJ, Rutala WA. 2001. The emerging nosocomial pathogens Cryptosporidium, Escherichia coli O157:H7, Helicobacter pylori, and hepatitis C: Epidemiology, environmental survival, efficacy of disinfection, and control measures. Infect Cont Hosp Ep 22:306-315.
172. Weigler BJ, Hird DW, Hilliard JK, Lerche NW, Roberts JA, Scott LM. 1993. Epidemiology of cercopithecine herpesvirus 1 (B virus) infection and shedding in a large breeding cohort of rhesus macaques. J Infect Dis 167:257-263.
173. Weiss LM, Edlind TD, Vossbrinck CR, Hashimoto T. 1999. Microsporidian molecular phylogeny: The fungal connection. J Eukaryot Microbiol 46:17S-18S.
174. Westmoreland SV, Rosen J, MacKey J, Romsey C, Xia DL, Visvesvara GS, Mansfield KG. 2004. Necrotizing meningoencephalitis and pneumonitis in a simian immunodeficiency virus-infected rhesus macaque due to Acanthamoeba. Vet Pathol 41:398-404.
175. Willy ME, Woodward RA, Thornton VB, Wolff AV, Flynn BM, Heath JL, Villamarzo YS, Smith S, Bellini WJ, Rota PA. 1999. Management of a measles outbreak among Old World nonhuman primates. Lab Anim Sci 49:42-48.
176. Wilson DW, Day PA, Brummer ME. 1984. Diarrhea associated with Cryptosporidium spp. in juvenile macaques. Vet Pathol 21:447-450.
177. Wong MM, Kozek WJ. 1974. Spontaneous toxoplasmosis in macaques: A report of four cases. Lab Anim Sci 24:273-278.
178. Wong MM, Karr SL Jr, Balamuth WB. 1975a. Experimental infections with pathogenic free-living amebae in laboratory primate hosts: I (A) A study on susceptibility to Naegleria fowleri. J Parasitol 61:199-208.
179. Wong MM, Karr SL Jr, Balamuth WB. 1975b. Experimental infections with pathogenic free-living amebae in laboratory primate hosts: I (B) A study on susceptibility to Acanthamoeba culbertsoni. J Parasitol 61:682-690.
180. Wong SW, Bergquam EP, Swanson RM, Lee FW, Shiigi SM, Avery NA, Fanton JW, Axthelm MK. 1999. Induction of B cell hyperplasia in simian immunodeficiency virus-infected rhesus macaques with the simian homologue of Kaposi's sarcoma-associated herpesvirus. J Exp Med 190:827-840.
181. Xiang Z, Li Y, Cun A, Yang W, Ellenberg S, Switzer WM, Kalish ML, Ertl HC. 2006. Chimpanzee adenovirus antibodies in humans, sub-Saharan Africa. Emerg Infect Dis 12:1596-1599.
182. Yanai T, Chalifoux LV, Mansfield KG, Lackner AA, Simon MA. 2000. Pulmonary cryptosporidiosis in simian immunodeficiency virus-infected rhesus macaques. Vet Pathol 37:472-475.
183. Yanai T, Simon MA, Doddy FD, Mansfield KG, Pauley D, Lackner AA. 1999. Nodular Pneumocystis carinii pneumonia in SIV-infected macaques. Vet Pathol 36:471-474.
184. Zhou D, Shen Y, Chalifoux L, Lee-Parritz D, Simon M, Sehgal PK, Zheng L, Halloran M, Chen ZW. 1999. Mycobacterium bovis bacille Calmette-Guerin enhances pathogenicity of simian immunodeficiency virus infection and accelerates progression to AIDS in macaques: A role of persistent T cell activation in AIDS pathogenesis. J Immunol 162:2204-2216.
185. Zwartouw HT, Boulter EA. 1984. Excretion of B virus in monkeys and evidence of genital infection. Lab Anim 18:65-70.