Expression of transforming growth factor-β1 and connective tissue growth factor in the capsule in a rat immobilized knee model

Upsala Journal of Medical Sciences

Volumn 113, Issue 2, 2008, Pages 221-234

  Hagiwara, Yoshihiro ^a   Chimoto, Eiichi ^a   Ichiro Takahashi, P ^b   Ando, Akira ^a   Sasano, Yasuyuki ^b   Itoi, Eiji ^a  

^a TOHOKU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b TOHOKU UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CONNECTIVE TISSUE GROWTH FACTOR; IMMEDIATE EARLY PROTEIN; MESSENGER RNA; PRIMER DNA; SIGNAL PEPTIDE; TRANSFORMING GROWTH FACTOR BETA1;

ANIMAL; ANIMAL MODEL; ARTICLE; CONTRACTURE; GENETICS; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; JOINT CAPSULE; KNEE; MALE; METABOLISM; NUCLEOTIDE SEQUENCE; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SPRAGUE DAWLEY RAT;

ANIMALS; BASE SEQUENCE; CONTRACTURE; DNA PRIMERS; IMMEDIATE-EARLY PROTEINS; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; JOINT CAPSULE; KNEE JOINT; MALE; MODELS, ANIMAL; RATS; RATS, SPRAGUE-DAWLEY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TRANSFORMING GROWTH FACTOR BETA1;

EID: 48949097324     PISSN: 03009734     EISSN: None     Source Type: Journal    
DOI: 10.3109/2000-1967-223     Document Type: Article

References (58)

1. Hagiwara Y, Saijyo Y, Chimoto E, Akita H, Sasano Y, Matsumoto F, Kokubun S (2006) Increased elasticity of capsule after immobilization in a rat knee experimental model assessed by scanning acoustic microscopy. Ups J Med Sci 111:303-313.
2. Trudel G., Desaulniers N, Uhthoff HK, Laneuville O (2001) Different levels of COX-1 and COX-2 enzymes in synoviocytes and chondrocytes during joint contracture formation. J Rheumatol 28:2066-2074.
3. Partridge REH, Duthie JJR (1963) Controlled trial of the effect of complete immobilization of the joints in rheumatoid arthritis. Ann Rheum Dis 22:91-99.
4. Gault SJ, Spyker JM (1969) Beneficial effect of immobilization of joints in rheumatoid and related arthritis: A splint study using sequential analysis. Arthritis Rheum 12:34-44.
5. Trudel GM, Seki M, Uhthoff HK (2000) Synovial adhesions are more important than pannus proliferation in the pathogenesis of knee joint contracture after immobilization: an experimental investigation in the rat. J Rheumatol 27:351-357.
6. Peacock EE (1966) Some biochemical and biophysical aspects of joint stiffness: role of collagen synthesis as opposed to altered molecular bonding. Ann Surg 164:1-12.
7. Damron TA, Greenwald TA, Breed A (1994) Chronologic outcome of surgical tendoachilles lengthening and natural history of gastroc-soleus contracture in cerebral palsy. A two-part study. Clin Orthop Relat Res 301:249-255.
8. Trudel, G., Jabi M, Uhthoff HK (1998) Intraarticular tissue proliferation after immobility: methods of assessment and preliminary results in rat knee joints. J Rheumatol 25:945-950
9. Kottke FJ, Pauley DL, Ptak RA (1966) The rationale for prolonged stretching for correction of shortening of connective tissue. Arch Phys Med Rehabil 47:345-352.
10. Evans BE, Eggers GWN, Butler JK, Blumel J (1960) Experimental immobilization and remobilization of rat knee joints. J Bone Joint Surg Am 42:737-758.
11. Enneking WF, Horowits M (1972) The intra-articular effects of immobilization on the human knee. J Bone Joint Surg Am 54:973-985.
12. Thaxter TH, Mann RA, Anderson CE (1965) Degeneration of immobilized knee joints in rats. J Bone Joint Surg Am 47:567-585.
13. Hall MC (1963) Cartilage changes after experimental immobilization of the knee joint of the young rat. J Bone Joint Surg Am 45:35-44.
14. Langenskiold A, Michelsson JE, Videman T (1979) Osteoarthritis of the knee in the rabbit produced by immobilization. Acta Orthop Scand 50:1-14.
15. Schollmeier G, Uhtoff HK, Sarkar K, Fukuhara K (1994) Effects of immobilization on the capsule of the canine glenohumeral joint. Clin Orthop 304:37-42.
16. Michelsson JE, Hunneyball IM (1984) Inflammatory involvement in rabbit knee following immobilization and resulting in osteoarthritis. Scand J Rhematol 13:273-281.
17. Finsterbush A, Friedman B (1973) Early changes in immobilized rabbits knee joints: a light and electron microscopic study. Clin Orthop 92:305-319.
18. Fiala O, Bartos F (1973) Traumatic pannus. I. Macroscopical and microscopical changes after experimental reconstruction of joint surface. Acta Orthop Scand 44:194-207.
19. Salter RB, Mcnell OR, Carbin R (1965) The pathological changes in articular cartilage associated with persistent joint deformity: An experimental investigation. In: D. Gordon, editor. Studies of rheumatoid disease: Proceedings of the Third Canadian Conference on Rheumatic Disease. Tronto: University of Tronto Press, pp33-47.
20. Akeson WH, Amiel D, Abel MF, Garfin SR, Woo SL (1987) Effects of immobilization on joints. Clin Orthop 219:28-37.
21. Woo SL, Matthews JV, Akeson WH, Amiel D, Convery FR (1975) Connective tissue response to immobility. Correlative study of biomechanical and biochemical measurements of normal and immobilized rabbit knees. Arthritis Rheum 18:257-264.
22. Akeson WH, Woo SL, Amiel D, Doty DH (1977) Rapid recovery from contracture in rabbit hindlimb. A correlative biomechanical and biochemical study. Clin Orthop Relat Res 122:359-365.
23. Sood SC (1971) A study of the effects of experimental immobilization on rabbit articular cartilage. J Anat 108:497-507.
24. Matsumoto F, Trudel G, Uhthoff, HK (2002) High collagen type I and low collagen type III levels in knee joint contracture: an immunohistochemical study with histological correlate. Acta Orthop Scand 73:335-343.
25. Akeson WH, Woo SL, Amiel D, Coutts RD, Daniel D (1973) The connective tissue response to immobility: biochemical changes in periarticular connective tissue of the immobilized rabbit knee. Clin Orthop Relat Res 93:356-362.
26. Roy S (1970) Ultrastructure of articular cartilage in experimental immobilization. Ann Rheum Dis 29:634-642.
27. Trudel G., Uhthoff HK, Brown M (1999) Extent and direction of joint motion limitation after prolonged immobility: an experimental study in the rat. Arch Phys Med Rehabil 80:1542-1547.
28. Trudel G., Uhthoff HK (2000) Contractures secondary to immobility: is the restriction articular or muscular? An experimental longitudinal study in the rat knee. Arch Phys Med Rehabil 81:6-13.
29. Mori T, Kawara S, Shinozaki M, Hayashi N, Kakinuma T, Igarashi A, Takigawa M, Nakanishi T, Takehara K (1999) Role and interaction of connective tissue growth factor with transforming growth factor-beta in persistent fibrosis: A mouse fibrosis model. J Cell Physiol 181:153-159.
30. Daniels JT, Schultz GS, Blalock TD, Garrett Q, Grotendorst GR, Dean NM, Khaw PT (2003) Mediation of Transforming Growth Factor-Stimulated Matrix Contraction Fibroblasts- A Role for Connective Tissue Growth Factor in Contractile Scarring. Am J Pathol 163:2043-2052.
31. Borde WA, Noble NA (1994) Transforming growth factor β in tissue fibrosis. N Engl J Med 331:1286-1292.
32. Shah M, Foreman DM, Ferguson MW (1995). Neutralization of TGF-β1 and TGF-β2 or exogenous addition of TGF-β3 to cutaneous rat wounds reduces scarring. J Cell Sci 108:985-1002.
33. Rodeo SA, Hannafin JA, Tom J, Warren RF, Wickiewicz TL (1997) Immunolocalization of cytokines and their receptors in adhesive capsulitis of the shoulder. J Orthop Res 15:427-436.
34. Okazaki R, Sakai A, Uezono Y, Ootsuyama A, Kunugita N, Nakamura T, Norimura T (2001) Sequential changes in transforming growth factor (TGF)-β1 concentration in synovial fluid and mRNA expression of TGFβ1 receptors in chondrocytes after immobilization of rabbit knees; J Bone Miner Metab 19:228-235.
35. Allen JB, Manthey CL, Hand AR, Ohura K, Ellingsworth L, Wahl SM (1990) Rapid onset of synovial inflammation and hyperplasia induced by transforming growth factor beta. J Exp Med 171:231-247.
36. Fava RA, Olsen NJ, Postlethwaite AE, Broadley KN, Dabidson JM, Nanney LB, Lucas C, Townes AS (1991) Transforming growth factor β1 (TGF-β) induced neutrophil recruitment to synovial tissues: implications for TGF-β-driven synovial inflammation and hyperplasia. J Exp Med 173:205-210.
37. Roberts AB, Sporn MB, Assoian RK, Smith JM, Roche NS Wakefield LM, Heine UI, Liotta LA, Falanga V, Kehrl JH, Fauci AS (1986) Transforming growth factor- β: rapid induction of fibrosis and angiogenesis in vivo and stimulation of collagen formation in vitro. Proc Natl Acad Sci US 83:4167-4171
38. Sasano Y, Zhi JX, Tsubota M, Takahashi I, Onodera K, Mizoguchi I, Kagayama M (2002) Gene expression of MMP8 and MMP13 during embryonic development of bone and cartilage in the rat mandible and hind limb. J Histochem Cytochem 50:325-332.
39. Hagiwara Y, Chimoto E, Ando A, Sasano Y, Hatori K, Itoi E (2007) Expression of type I collagen in the capsule of a contracture knee in a rat model. Ups J Med Sci.112: 356-365.
40. Trudel G.. Differentiating the myogenic and arthrogenic components of joint contractures. An experimental study on the rat knee joint (1997) Int J Rehabil Res 20:397-404.
41. Chimoto E, Hagiwara Y, Ando A, Itoi E (2007) Progression of an arthrogenic motion restriction after immobilization in a rat experimental knee model. Ups J Med Sci.112: 347-355.
42. Sporn MB, Roberts AM, Wakefield LM, Crombrugghe B (1987) Some recent advances in the chemistry and biology of transforming growth factor-beta. J Cell Biol 105:1039-1045.
43. Tsuji T, Okada F, Yamaguchi K, Nakamura T (1990) Molecular cloning of the large subunit of transforming growth factor type β masking protein and expression of the mRNA in various rat tissues. Proc Natl Acad Sci USA 87:8835-8839.
44. Varge J, Rosenbloom J, Jimenez SA (1987) Transforming growth factor-β causes a persistent increase in steady-state amounts of type I and type III collagen and fibronectin mRNAs in normal human dermal fibroblasts. Biochemistry 297:597-604.
45. Roberts AB, Sporn MB (1993) Physiological actions and clinical applications of transforming growth factor-β. Growth Factors 8:1-9.
46. Fukui N, Tashiro T, Hiraoka H, Oda H, Nakamura K (2000) Adhesion formation can be reduced by the suppression of transforming growth factor-β1 Activity. J Orthop Res 18:212-219.
47. Wahl SM, Allen JB, Costa GL, Wong HL, Dasch JR (1993) Reversal of acute and chronic synovial inflammation by anti-transforming growth factor beta. J Exp Med 117:225-230.
48. Inkinen K, Wolff H, Lindroos P, Ahonen J (2003) Connective tissue growth factor and its correlation to other growth factor in experimental granulation tissue. Connect Tissue Res 44:19-29.
49. Grotendorst GR, Okochi H, Hayashi N (1996) A novel TGF-β response element controls the expression of the connective tissue growth factor (CTGF) gene. Cell Growth Differ 7:469-480.
50. Grotendorst GR (1997) Connective tissue growth factor: A mediator of TGF-beta action on fibroblasts. Cytokine Growth Factor Rev 8:171-179.
51. Igarashi A, Nashiro K, Kikuchi K, Sato S, Ihn H, Grotendorst GR (1995) Significant correlation between connective tissue growth factor gene expression and skin sclerosis in tissue sections from patients with systemic sclerosis. J Invest Dermatol 105:280-284.
52. Igarashi A, Nashiro K, Kikuchi K, Sato S, Ihn H, Fujimoto M, Grotendorst GR, Takehara K (1996) Connective tissue growth factor gene expression in tissue sections from localized scleroderma, keloid and other fibrotic skin disorders. J Invest Dermatol 106:729-733.
53. Ito Y, Aten J, Bende RJ, Oemar BS, Rabelink TJ, Weening JJ, Goldschmeding R (1998) Expression of connective tissue growth factor in human renal fibrosis. Kidney Int 53:853-861.
54. Dammeier J, Brauchle M, Falk W, Grotendorst GR, Werner S (1998) Connective tissue growth factor. A novel regulator of mucosal repair and fibrosis in inflammatory bowel disease? Int J Biochem Cell Biol 30:909-922.
55. di Mola FF, Friess H, Martignoni ME, Di Sebastiano P, Zimmermann A, Innocenti P, Graber H, Gold LI, Korc M, Buchler MW (1999) Connective tissue growth factor is a regulator for fibrosis in human chronic pancreatitis. Ann Surg 230:63-71.
56. Lasky JA, Ortiz LA, Tonthat B, Hoyle GW, Corti M, Athas G, Lungarella G, Brody A, Friedmann M (1998) Connective tissue mRNA expression is upregulated in bleomycin-induced lung fibrosis. Am J Physiol 275:365-371.
57. Paradis V, Dargere D, Vidaud M, De Gouville AC, Huet S, Martinez V, Gauthier JM, Ba N, Sobesky R, Ratziu V, Bedossa P (1999) Expression of connective tissue growth factor in experimental rat and human liver fibrosis. Hepatology 30:968-976.
58. Takehara K (2003) Hypothesis: pathogenesis of systemic sclerosis. J Rheumatol 30:755-759.