A novel immunoprecipitation strategy identifies a unique functional mimic of the glial cell line-derived neurotrophic factor family ligands in the pathogen Trypanosoma cruzi

Infection and Immunity

Volumn 76, Issue 8, 2008, Pages 3530-3538

  Lu, Bo ^a   PereiraPerrin, Mercio ^a  

^a TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANAZOLENE SODIUM; GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR; IMMUNOGLOBULIN G; LIGAND; POLYPEPTIDE; PROTEIN TYROSINE KINASE; SEPHAROSE; MEMBRANE PROTEIN; PROTOZOAL PROTEIN; PROTOZOON ANTIBODY;

ARTICLE; IMMUNOBLOTTING; IMMUNOPRECIPITATION; NERVOUS TISSUE; NONHUMAN; OUTER MEMBRANE; PARASITE; PERIPHERAL NERVOUS SYSTEM; PHEOCHROMOCYTOMA CELL; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; SCREENING; TRYPANOSOMA CRUZI; ANIMAL; CELL LINE; CELL SURVIVAL; CHEMISTRY; IMMUNOLOGY; METHODOLOGY; MOUSE; NEURITE; PROTEIN BINDING; SENSITIVITY AND SPECIFICITY;

ANIMALS; ANTIBODIES, PROTOZOAN; CELL LINE; CELL SURVIVAL; GLIAL CELL LINE-DERIVED NEUROTROPHIC FACTORS; IMMUNOBLOTTING; IMMUNOPRECIPITATION; MEMBRANE PROTEINS; MICE; NEURITES; PROTEIN BINDING; PROTOZOAN PROTEINS; SENSITIVITY AND SPECIFICITY; TRYPANOSOMA CRUZI;

EID: 48849117935     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.00411-08     Document Type: Article

References (48)

1. Airaksinen, M. S., and M. Saarma. 2002. The GDNF family: signalling, biological functions and therapeutic value. Nat. Rev. Neurosci. 3:383-394.
2. Baloh, R. H., H. Enomoto, E. M. Johnson, Jr., and J. Milbrandt. 2000. The GDNF family ligands and receptors-implications for neural development Curr. Opin. Neurobiol. 10:103-110.
3. Baloh, R. H., M. G. Tansey, P. A. Lampe, T. J. Fahrner, H. Enomoto, K. S. Simburger, M. L. Leitner, T. Araki, E. M. Johnson, Jr., and J. Milbrandt. 1998. Artemin, a novel member of the GDNF ligand family, supports peripheral and central neurons and signals through the GFRalpha3-RET receptor complex. Neuron 21:1291-1302.
4. Birchmeier, C., W. Birchmeier, E. Gherardi, and G. F. Vande Woude. 2003. Met, metastasis, motility and more. Nat. Rev. Mol. Cell Biol. 4:915-925.
5. Braun, L., S. Dramsi, P. Dehoux, H. Bierne, G. Lindahl, and P. Cossart. 1997. InlB: an invasion protein of Listeria monocytogenes with a novel type of surface association. Mol. Microbiol. 25:285-294.
6. Chuenkova, M., and M. E. Pereira. 1995. Trypanosoma cruzi trans-sialidase: enhancement of virulence in a murine model of Chagas' disease. J. Exp. Med. 181:1693-1703.
7. Chuenkova, M. V., F. B. Furnari, W. K. Cavenee, and M. A. Pereira. 2001. Trypanosoma cruzi trans-sialidase: a potent and specific survival factor for human Schwann cells by means of phosphatidylinositol 3-kinase/Akt signaling. Proc. Natl. Acad. Sci. USA 98:9936-9941.
8. Chuenkova, M. V., and M. A. Pereira. 2003. PDNF, a human parasite-derived mimic of neurotrophic factors, prevents caspase activation, free radical formation, and death of dopaminergic cells exposed to the Parkinsonism-inducing neurotoxin MPP+. Brain Res. Mol. Brain Res. 119:50-61.
9. Chuenkova, M. V., and M. A. Pereira. 2000. A trypanosomal protein synergizes with the cytokines ciliary neurotrophic factor and leukemia inhibitory factor to prevent apoptosis of neuronal cells. Mol. Biol. Cell 11:1487-1498.
10. Chuenkova, M. V., and M. PereiraPerrin. 2004. Chagas' disease parasite promotes neuron survival and differentiation through TrkA nerve growth factor receptor. J. Neurochem. 91:385-394.
11. Chuenkova, M. V., and M. PereiraPerrin. 2006. Enhancement of tyrosine hydroxylase expression and activity by Trypanosoma cruzi parasite-derived neurotrophic factor. Brain Res. 1099:167-175.
12. Chuenkova, M. V., and M. PereiraPerrin. 2005. A synthetic peptide modeled on PDNF, Chagas' disease parasite neurotrophic factor, promotes survival and differentiation of neuronal cells through TrkA receptor. Biochemistry 44:15685-15694.
13. Cossart, P., and P. J. Sansonetti. 2004. Bacterial invasion: the paradigms of enteroinvasive pathogens. Science 304:242-248.
14. de Melo-Jorge, M., and M. PereiraPerrin. 2007. The Chagas' disease parasite Trypanosoma cruzi exploits nerve growth factor receptor TrkA to infect mammalian hosts. Cell Host Microbe 1:251-261.
15. Gao, W., and M. A. Pereira. 2001. Trypanosoma cruzi trans-sialidase potentiates T cell activation through antigen-presenting cells: role of IL-6 and Bruton's tyrosine kinase. Eur. J. Immunol. 31:1503-1512.
16. Gardell, L. R., R. Wang, C. Ehrenfels, M. H. Ossipov, A. J. Rossomando, S. Miller, C. Buckley, A. K. Cai, A. Tse, S. F. Foley, B. Gong, L. Walus, P. Carmillo, D. Worley, C. Huang, T. Engber, B. Pepinsky, R. L. Cate, T. W. Vanderah, J. Lai, D. W. Sah, and F. Porreca. 2003. Multiple actions of systemic artemin in experimental neuropathy. Nat. Med. 9:1383-1389.
17. Gellin, B. G., and C. V. Broome. 1989. Listeriosis. JAMA 261:1313-1320.
18. Hishiki, T., Y. Nimura, E. Isogai, K. Kondo, S. Ichimiya, Y. Nakamura, T. Ozaki, S. Sakiyama, M. Hirose, N. Seki, H. Takahashi, N. Ohnuma, M. Tanabe, and A. Nakagawara. 1998. Glial cell line-derived neurotrophic factor/neurturin-induced differentiation and its enhancement by retinoic acid in primary human neuroblastomas expressing c-Ret, GFR alpha-1, and GFR alpha-2. Cancer Res. 58:2158-2165.
19. Hoff, R., R. S. Teixeira, J. S. Carvalho, and K. E. Mott. 1978. Trypanosoma cruzi in the cerebrospinal fluid during the acute stage of Chagas' disease. N. Engl. J. Med. 298:604-606.
20. Huang, E. J., and L. F. Reichardt. 2001. Neurotrophins: roles in neuronal development and function. Annu. Rev. Neurosci. 24:677-736.
21. Huang, E. J., and L. F. Reichardt. 2003. Trk receptors: roles in neuronal signal transduction. Annu. Rev. Biochem. 72:609-642.
22. Jullien, J., V. Guili, L. F. Reichardt, and B. B. Rudkin. 2002. Molecular kinetics of nerve growth factor receptor trafficking and activation. J. Biol. Chem. 277:38700-38708.
23. Kedzierski, L., J. Montgomery, D. Bullen, J. Curtis, E. Gardiner, A. Jimenez-Ruiz, and E. Handman. 2004. A leucine-rich repeat motif of Leishmania parasite surface antigen 2 binds to macrophages through the complement receptor 3. J. Immunol. 172:4902-4906.
24. Kim, S. K., and J. C. Boothroyd. 2005. Stage-specific expression of surface antigens by Toxoplasma gondii as a mechanism to facilitate parasite persistence. J. Immunol. 174:8038-8048.
25. Koberle, F. 1968. Chagas' disease and Chagas' syndromes: the pathology of American trypanosomiasis. Adv. Parasitol. 6:63-116.
26. Levi-Montalcini, R. 1987. The nerve growth factor 35 years later. Science 237:1154-1162.
27. Ley, V., N. W. Andrews, E. S. Robbins, and V. Nussenzweig. 1988. Amastigotes of Trypanosoma cruzi sustain an infective cycle in mammalian cells. J. Exp. Med. 168:649-659.
28. Lin, L. F., D. Mismer, J. D. Lile, L. G. Armes, E. T. Butler III, J. L. Vannice, and F. Collins. 1989. Purification, cloning, and expression of ciliary neurotrophic factor (CNTF). Science 246:1023-1025.
29. Lui, V. C., E. T. Samy, M. H. Sham, L. M. Mulligan, and P. K. Tam. 2002. Glial cell line-derived neurotrophic factor family receptors are abnormally expressed in aganglionic bowel of a subpopulation of patients with Hirschsprung's disease. Lab. Investig. 82:703-712.
30. Massague, J., and Y. G. Chen. 2000. Controlling TGF-beta signaling. Genes Dev. 14:627-644.
31. Montgomery, J., T. Ilg, J. K. Thompson, B. Kobe, and E. Handman. 2000. Identification and predicted structure of a leucine-rich repeat motif shared by Leishmania major proteophosphoglycan and parasite surface antigen 2. Mol. Biochem. Parasitol. 107:289-295.
32. Newgreen, D., and H. M. Young. 2002. Enteric nervous system: development and developmental disturbances - part 2. Pediatr. Dev. Pathol. 5:329-349.
33. Niemann, H. H., V. Jager, P. J. Butler, J. van den Heuvel, S. Schmidt, D. Ferraris, E. Gherardi, and D. W. Heinz. 2007. Structure of the human receptor tyrosine kinase met in complex with the Listeria invasion protein InlB. Cell 130:235-246.
34. Pereira, M. E. 1983. A rapid and sensitive assay for neuraminidase using peanut lectin hemagglutination: application to Vibrio cholera and Trypanosoma cruzi. J. Immunol. Methods 63:25-34.
35. Powers, J. F., M. J. Evinger, P. Tsokas, S. Bedri, J. Alroy, M. Shahsavari, and A. S. Tischler. 2000. Pheochromocytoma cell lines from heterozygous neurofibromatosis knockout mice. Cell Tissue Res. 302:309-320.
36. Prioli, R. P., J. S. Mejia, and M. E. Pereira. 1990. Monoclonal antibodies against Trypanosoma cruzi neuraminidase reveal enzyme polymorphism, recognize a subset of trypomastigotes, and enhance infection in vitro. J. Immunol. 144:4384-4391.
37. Rock, R. B., and P. K. Peterson. 2006. Microglia as a pharmacological target in infectious and inflammatory diseases of the brain. J. Neuroimmune Pharmacol. 1:117-126.
38. Sanicola, M., C. Hession, D. Worley, P. Carmillo, C. Ehrenfels, L. Walus, S. Robinson, G. Jaworski, H. Wei, R. Tizard, A. Whitty, R. B. Pepinsky, and R. L. Cate. 1997. Glial cell line-derived neurotrophic factor-dependent RET activation can be mediated by two different cell-surface accessory proteins. Proc. Natl. Acad. Sci. USA 94:6238-6243.
39. Sariola, H., and M. Saarma. 2003. Novel functions and signalling pathways for GDNF. J. Cell Sci. 116:3855-3862.
40. Schenkman, S., D. Eichinger, M. E. Pereira, and V. Nussenzweig. 1994. Structural and functional properties of Trypanosoma trans-sialidase. Annu. Rev. Microbiol. 48:499-523.
41. Shen, Y., M. Naujokas, M. Park, and K. Ireton. 2000. InlB-dependent internalization of Listeria is mediated by the Met receptor tyrosine kinase. Cell 103:501-510.
42. Sibley, L. D. 2004. Intracellular parasite invasion strategies. Science 304:248-253.
43. Slevin, J. T., G. A. Gerhardt, C. D. Smith, D. M. Gash, R. Kryscio, and B. Young. 2005. Improvement of bilateral motor functions in patients with Parkinson disease through the unilateral intraputaminal infusion of glial cell line-derived neurotrophic factor. J. Neurosurg. 102:216-222.
44. Takeda, K., and S. Akira. 2003. Toll receptors and pathogen resistance. Cell. Microbiol. 5:143-153.
45. Tanowitz, H. B., L. V. Kirchhof, D. Simon, S. A. Morris, L. M. Weiss, and M. Wittner. 1992. Chagas' disease. Clin. Microbiol. Rev. 5:400-419.
46. Townsend, G. C., and W. M. Scheid. 1998. Infections of the central nervous system. Adv. Intern. Med. 43:403-447.
47. Wang, X., R. H. Baloh, J. Milbrandt, and K. C. Garcia. 2006. Structure of artemin complexed with its receptor GFRa3: convergent recognition of glial cell line-derived neurotrophic factors. Structure 14:1083-1092.
48. Yefenof, E. 2000. Complement receptor 3 (CR3): a public transducer of innate immunity signals in macrophages. Adv. Exp. Med. Biol. 479:15-25.