-
2
-
-
0012375774
-
Permeability
-
Avdeef A. (Ed), John Wiley & Sons, Hoboken
-
Avdeef A. Permeability. In: Avdeef A. (Ed). Absorption and Drug Development (2003), John Wiley & Sons, Hoboken 116-246
-
(2003)
Absorption and Drug Development
, pp. 116-246
-
-
Avdeef, A.1
-
3
-
-
0034778663
-
Drug absorption in vitro model: filter-immobilized artificial membranes Studies of the permeability properties of lactones in piper methysticum forst
-
Avdeef A., Strafford M., Block E., Balogh M.P., Chambliss W., and Khan I. Drug absorption in vitro model: filter-immobilized artificial membranes Studies of the permeability properties of lactones in piper methysticum forst. Eur. J. Pharm. Sci. 14 (2001) 271-280
-
(2001)
Eur. J. Pharm. Sci.
, vol.14
, pp. 271-280
-
-
Avdeef, A.1
Strafford, M.2
Block, E.3
Balogh, M.P.4
Chambliss, W.5
Khan, I.6
-
4
-
-
0036692339
-
Theoretical and experimental exploration of the lipophilicity of zwitterionic drugs in the 1.2-dichloroethane/water system
-
Bouchard G., Pagliara A., Carrupt P.A., Testa B., Gobry V., and Girault H.H. Theoretical and experimental exploration of the lipophilicity of zwitterionic drugs in the 1.2-dichloroethane/water system. Pharm. Res. 19 (2002) 1150-1159
-
(2002)
Pharm. Res.
, vol.19
, pp. 1150-1159
-
-
Bouchard, G.1
Pagliara, A.2
Carrupt, P.A.3
Testa, B.4
Gobry, V.5
Girault, H.H.6
-
5
-
-
0033179099
-
Combined molecular lipophilicity descriptors and their role in understanding intramolecular effects
-
Caron G., Reymond F., Carrupt P.A., Girault H.H., and Testa B. Combined molecular lipophilicity descriptors and their role in understanding intramolecular effects. Pharm. Sci. Technol. Today 2 (1999) 327-335
-
(1999)
Pharm. Sci. Technol. Today
, vol.2
, pp. 327-335
-
-
Caron, G.1
Reymond, F.2
Carrupt, P.A.3
Girault, H.H.4
Testa, B.5
-
6
-
-
84962359573
-
High throughput artificial membrane permeability assay for blood-brain barrier
-
Di L., Kerns E.H., Fan K., McConnell O.J., and Carter G.T. High throughput artificial membrane permeability assay for blood-brain barrier. Eur. J. Med. Chem. 38 (2003) 223-232
-
(2003)
Eur. J. Med. Chem.
, vol.38
, pp. 223-232
-
-
Di, L.1
Kerns, E.H.2
Fan, K.3
McConnell, O.J.4
Carter, G.T.5
-
7
-
-
0026064678
-
Percutaneous penetration of drugs: a quantitative structure-permeability relationship study
-
El Tayar N., Tsai R.S., Testa B., Carrupt P.A., Hansch C., and Leo A. Percutaneous penetration of drugs: a quantitative structure-permeability relationship study. J. Pharm. Sci. 80 (1991) 744-749
-
(1991)
J. Pharm. Sci.
, vol.80
, pp. 744-749
-
-
El Tayar, N.1
Tsai, R.S.2
Testa, B.3
Carrupt, P.A.4
Hansch, C.5
Leo, A.6
-
8
-
-
17144428075
-
High-throughput lipophilicity measurement with immobilized artificial membranes
-
Faller B., Grimm H.P., Loeuillet-Ritzler F., Arnold S., and Briand X. High-throughput lipophilicity measurement with immobilized artificial membranes. J. Med. Chem. 48 (2005) 2571-2576
-
(2005)
J. Med. Chem.
, vol.48
, pp. 2571-2576
-
-
Faller, B.1
Grimm, H.P.2
Loeuillet-Ritzler, F.3
Arnold, S.4
Briand, X.5
-
9
-
-
0036846646
-
Quantitative structure-permeation relationships for solute transport across silicone membranes
-
Geinoz S., Rey S., Boss G., Bunge A.L., Guy R.H., Carrupt P.A., Reist M., and Testa B. Quantitative structure-permeation relationships for solute transport across silicone membranes. Pharm. Res. 19 (2002) 1622-1629
-
(2002)
Pharm. Res.
, vol.19
, pp. 1622-1629
-
-
Geinoz, S.1
Rey, S.2
Boss, G.3
Bunge, A.L.4
Guy, R.H.5
Carrupt, P.A.6
Reist, M.7
Testa, B.8
-
10
-
-
1942534164
-
A comparison of the solvation properties of 2-nitrophenyloctyl ether, nitrobenzene, and n-octanol as assessed by ion transfer experiments
-
Gulaboski R., Galland A., Bouchard G., Caban K., Kretschmer A., Carrupt P.A., Stojek Z., Girault H.H., and Scholz F. A comparison of the solvation properties of 2-nitrophenyloctyl ether, nitrobenzene, and n-octanol as assessed by ion transfer experiments. J. Phys. Chem. B 108 (2004) 4565-4572
-
(2004)
J. Phys. Chem. B
, vol.108
, pp. 4565-4572
-
-
Gulaboski, R.1
Galland, A.2
Bouchard, G.3
Caban, K.4
Kretschmer, A.5
Carrupt, P.A.6
Stojek, Z.7
Girault, H.H.8
Scholz, F.9
-
11
-
-
0032568397
-
Physicochemical high throughput screening: parallel artificial membrane permeation assay in the description of passive absorption processes
-
Kansy M., Senner F., and Gubernator K. Physicochemical high throughput screening: parallel artificial membrane permeation assay in the description of passive absorption processes. J. Med. Chem. 41 (1998) 1007-1010
-
(1998)
J. Med. Chem.
, vol.41
, pp. 1007-1010
-
-
Kansy, M.1
Senner, F.2
Gubernator, K.3
-
12
-
-
33644758293
-
Immobilized pH gradient gel cell to study the pH dependence of drug lipophilicity
-
Lam H.T., Pereira C.M., Roussel C., Carrupt P.A., and Girault H.H. Immobilized pH gradient gel cell to study the pH dependence of drug lipophilicity. Anal. Chem. 78 (2006) 1503-1508
-
(2006)
Anal. Chem.
, vol.78
, pp. 1503-1508
-
-
Lam, H.T.1
Pereira, C.M.2
Roussel, C.3
Carrupt, P.A.4
Girault, H.H.5
-
13
-
-
0346753672
-
Partition coefficients of ionizable compounds in o-nitrophenyl octyl ether/water measured by the potentiometric method
-
Liu X., Bouchard G., Girault H.H., Testa B., and Carrupt P.A. Partition coefficients of ionizable compounds in o-nitrophenyl octyl ether/water measured by the potentiometric method. Anal. Chem. 75 (2003) 7036-7039
-
(2003)
Anal. Chem.
, vol.75
, pp. 7036-7039
-
-
Liu, X.1
Bouchard, G.2
Girault, H.H.3
Testa, B.4
Carrupt, P.A.5
-
14
-
-
0347382366
-
Solvatochromic analysis of partition coefficients in the o-nitrophenyloctylether (o-NPOE)/water system
-
Liu X., Bouchard G., Müller N., Galland A., Girault H.H., Testa B., and Carrupt P.A. Solvatochromic analysis of partition coefficients in the o-nitrophenyloctylether (o-NPOE)/water system. Helv. Chim. Acta 86 (2003) 3533-3547
-
(2003)
Helv. Chim. Acta
, vol.86
, pp. 3533-3547
-
-
Liu, X.1
Bouchard, G.2
Müller, N.3
Galland, A.4
Girault, H.H.5
Testa, B.6
Carrupt, P.A.7
-
15
-
-
33745642435
-
Parallel artificial membrane permeability assay: a new membrane for the fast prediction of passive human skin permeability
-
Ottaviani G., Martel S., and Carrupt P.A. Parallel artificial membrane permeability assay: a new membrane for the fast prediction of passive human skin permeability. J. Med. Chem. 49 (2006) 3948-3954
-
(2006)
J. Med. Chem.
, vol.49
, pp. 3948-3954
-
-
Ottaviani, G.1
Martel, S.2
Carrupt, P.A.3
-
16
-
-
33748658297
-
Intermolecular forces expressed in 1,2-dichloroethane/water partition coefficient: a solvatochromic analysis.
-
Steyaert G., Lisa G., Gaillard P., Boss G., Reymond F., Girault H.H., Carrupt P.A., and Testa B. Intermolecular forces expressed in 1,2-dichloroethane/water partition coefficient: a solvatochromic analysis. J. Chem. Soc., Faraday Trans. 93 (1997) 401-406
-
(1997)
J. Chem. Soc., Faraday Trans.
, vol.93
, pp. 401-406
-
-
Steyaert, G.1
Lisa, G.2
Gaillard, P.3
Boss, G.4
Reymond, F.5
Girault, H.H.6
Carrupt, P.A.7
Testa, B.8
-
17
-
-
0033820354
-
The influence of lipophilicity on the pharmacokinetic behavior of drugs: concepts and examples
-
Testa B., Crivori P., Reist M., and Carrupt P.A. The influence of lipophilicity on the pharmacokinetic behavior of drugs: concepts and examples. Perspect. Drug Discov. Design 19 (2000) 179-211
-
(2000)
Perspect. Drug Discov. Design
, vol.19
, pp. 179-211
-
-
Testa, B.1
Crivori, P.2
Reist, M.3
Carrupt, P.A.4
-
19
-
-
11344253864
-
Numerical simulation of two-phase partition chromatography in microchannels for moderated log P measurements
-
Ulmeanu S.M., Josserand J., Jensen H., Bouchard G., Carrupt P.A., and Girault H.H. Numerical simulation of two-phase partition chromatography in microchannels for moderated log P measurements. J. Chromatogr. 1063 (2005) 89-97
-
(2005)
J. Chromatogr.
, vol.1063
, pp. 89-97
-
-
Ulmeanu, S.M.1
Josserand, J.2
Jensen, H.3
Bouchard, G.4
Carrupt, P.A.5
Girault, H.H.6
-
20
-
-
21144467893
-
Hydrogen-bonding capacity and brain penetration
-
van de Waterbeemd H., and Kansy M. Hydrogen-bonding capacity and brain penetration. Chimia 46 (1992) 299-303
-
(1992)
Chimia
, vol.46
, pp. 299-303
-
-
van de Waterbeemd, H.1
Kansy, M.2
-
21
-
-
85056917458
-
Skin absorption databases and predictive equations
-
Guy R.H., and Hadgraft J. (Eds), Marcel Dekker, New York
-
Vecchia B.E., and Bunge A. Skin absorption databases and predictive equations. In: Guy R.H., and Hadgraft J. (Eds). Transdermal Drug Delivery (2003), Marcel Dekker, New York 57-141
-
(2003)
Transdermal Drug Delivery
, pp. 57-141
-
-
Vecchia, B.E.1
Bunge, A.2
-
22
-
-
0035866672
-
High-throughput permeability pH profile and high-throughput alkane/water log P with artificial membranes
-
Wohnsland F., and Faller B. High-throughput permeability pH profile and high-throughput alkane/water log P with artificial membranes. J. Med. Chem. 44 (2001) 923-930
-
(2001)
J. Med. Chem.
, vol.44
, pp. 923-930
-
-
Wohnsland, F.1
Faller, B.2
-
23
-
-
0027276380
-
An approach to the design of brain-penetrating histaminergic agonists
-
Young R.C., Ganellin C.R., Griffiths R., Mitchell R.C., Parsons M.E., Saunders D., and Sore N.E. An approach to the design of brain-penetrating histaminergic agonists. Eur. J. Med. Chem. 28 (1993) 201-211
-
(1993)
Eur. J. Med. Chem.
, vol.28
, pp. 201-211
-
-
Young, R.C.1
Ganellin, C.R.2
Griffiths, R.3
Mitchell, R.C.4
Parsons, M.E.5
Saunders, D.6
Sore, N.E.7
-
24
-
-
0023902147
-
2 receptor histamine antagonists
-
2 receptor histamine antagonists. J. Med. Chem. 31 (1988) 656-671
-
(1988)
J. Med. Chem.
, vol.31
, pp. 656-671
-
-
Young, R.C.1
Mitchell, R.C.2
Brown, T.H.3
Ganellin, C.R.4
Griffiths, R.5
Jones, M.6
Rana, K.K.7
Saunders, D.8
Smith, I.R.9
Sore, N.E.10
Wilks, T.J.11
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