Voxel-based analysis of11C-PIB scans for diagnosing Alzheimer's disease

Journal of Nuclear Medicine

Volumn 49, Issue 8, 2008, Pages 1262-1269

  Mikhno, Arthur ^a,d   Devanand, Davangere ^a,b   Pelton, Gregory ^a,b   Cuasay, Katrina ^a   Gunn, Roger ^c   Upton, Neil ^c   Lai, Robert Y ^c   Libri, Vincenzo ^c   Mann, J John ^a,b   Parsey, Ramin V ^a,b  

^a NEW YORK STATE PSYCHIATRIC INSTITUTE   (United States)

^b Och Spine at New York Presbyterian Hospitals   (United States)

^c GLAXOSMITHKLINE   (United Kingdom)

^d NONE   (United States)

Author keywords

Alzheimer's; Diagnosis; PET; PIB; Voxel

Indexed keywords

AMYLOID; N METHYL 2 (4 METHYLAMINOPHENYL) 6 HYDROXYBENZOTHIAZOLE C 11; RADIOPHARMACEUTICAL AGENT; UNCLASSIFIED DRUG;

ADULT; AGED; ALZHEIMER DISEASE; ARTICLE; AUTOMATION; BINDING AFFINITY; BRAIN MAPPING; BRAIN SCINTISCANNING; CALCULATION; CLINICAL ARTICLE; COMPARATIVE STUDY; COMPUTER PROGRAM; CONTROLLED STUDY; DRUG UPTAKE; FEMALE; GRAY MATTER; HUMAN; MALE; NUCLEAR MAGNETIC RESONANCE IMAGING; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; STATISTICAL ANALYSIS; STATISTICAL PARAMETERS; VALIDATION PROCESS;

AGED; AGED, 80 AND OVER; ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN; BENZOTHIAZOLES; FEMALE; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; POSITRON-EMISSION TOMOGRAPHY; RADIOPHARMACEUTICALS; SENILE PLAQUES;

EID: 48749132611     PISSN: 01615505     EISSN: None     Source Type: Journal    
DOI: 10.2967/jnumed.107.049932     Document Type: Article

References (38)

1. Minino AM, Heron MP, Murphy SL, Kochanek KD, Centers for Disease Control and Prevention National Center for Health Statistics National Vital Statistics System. Deaths: final data for 2004. Natl Vital Stat Rep. 2007;55:1-119.
2. Zamrini E, De Santi S, Tolar M. Imaging is superior to cognitive testing for early diagnosis of Alzheimer's disease. Neurobiol Aging. 2004;25:685-691.
3. Thal DR, Rub U, Orantes M, Braak H. Phases of Aβ-deposition in the human brain and its relevance for the development of AD. Neurology. 2002;58:1791-1800.
4. Klunk WE, Engler H, Nordberg A, et al. Imaging brain amyloid in Alzheimer's disease with Pittsburgh Compound-B. Ann Neurol. 2004;55:306-319.
5. Rowe CC, Ng S, Ackermann U, et al. Imaging beta-amyloid burden in aging and dementia. Neurology. 2007;68:1718-1725.
6. 11C]PIB in a nondemented population: potential antecedent marker of Alzheimer disease. Neurology. 2006;67:446-452.
7. 11C]PIB uptake in Alzheimer disease. Neurology. 2006;67:1575-1580.
8. 11C]Pittsburgh compound B PET for early diagnosis of Alzheimer's disease. Neuroimage. 2007;36:298-312.
9. Kanetaka H, Matsuda H, Asada T, et al. Effects of partial volume correction on discrimination between very early Alzheimer's dementia and controls using brain perfusion SPECT. Eur J Nucl Med Mol Imaging. 2004;31:975-980.
10. Rousset OG, Ma Y, Evans AC. Correction for partial volume effects in PET: principle and validation. J Nucl Med. 1998;39:904-911.
11. Lopresti BJ, Klunk WE, Mathis CA, et al. Simplified quantification of Pittsburgh Compound B amyloid imaging PET studies: a comparative analysis. J Nucl Med. 2005;46:1959-1972.
12. 18F-FDG PET for detection of Alzheimer's disease. J Nucl Med. 2007;48:547-552.
13. McKhann G, Drachman D, Folstein M, Katzman R, Price D, Stadlan EM. Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology. 1984;34:939-944.
14. Parsey RV, Sokol LO, Belanger MJ, et al. Amyloid plaque imaging agent [C-11]-6-OH-BTA-1: biodistribution and radiation dosimetry in baboon. Nucl Med Commun. 2005;26:875-880.
15. Watson CC, Newport D, Casey ME. A single scatter simulation technique for scatter correction in 3D PET. In: Grangeat P, Amans J-L, eds. Three Dimensional Image Reconstruction in Radiology and Nuclear Medicine. Dordrecht, The Netherlands: Kluwer Academic; 1996:255-268.
16. 2 receptor parameter measurements in ventral striatum. J Cereb Blood Flow Metab. 2001;21:1034-1057.
17. Jenkinson M, Smith S. A global optimisation method for robust affine registration of brain images. Med Image Anal. 2001;5:143-156.
18. Smith SM. Fast robust automated brain extraction. Hum Brain Mapp. 2002;17:143-155.
19. Ashburner J, Friston KJ. Nonlinear spatial normalization using basis functions. Hum Brain Mapp. 1999;7:254-266.
20. Ashburner J, Friston KJ. Unified segmentation. Neuroimage. 2005;26:839-851.
21. Logan J, Fowler JS, Volkow ND, Wang GJ, Ding YS, Alexoff DL. Distribution volume ratios without blood sampling from graphical analysis of PET data. J Cereb Blood Flow Metab. 1996;16:834-840.
22. Joachim CL, Morris JH, Selkoe DJ. Diffuse senile plaques occur commonly in the cerebellum in Alzheimer's disease. Am J Pathol. 1989;135:309-319.
23. Price JC, Klunk WE, Lopresti BJ, et al. Kinetic modeling of amyloid binding in humans using PET imaging and Pittsburgh Compound-B. J Cereb Blood Flow Metab. 2005;25:1528-1547.
24. Ziolko SK, Weissfeld LA, Klunk WE, et al. Evaluation of voxel-based methods for the statistical analysis of PIB PET amyloid imaging studies in Alzheimer's disease. Neuroimage. 2006;33:94-102.
25. Logan J, Fowler JS, Volkow ND, Ding YS, Wang GJ, Alexoff DL. A strategy for removing the bias in the graphical analysis method. J Cereb Blood Flow Metab. 2001;21:307-320.
26. Kimura Y, Naganawa M, Shidahara M, Ikoma Y, Watabe H. PET kinetic analysis: pitfalls and a solution for the Logan plot. Ann Nucl Med. 2007;21:1-8.
27. Hoffman EJ, Huang SC, Phelps ME. Quantitation in positron emission computed tomography: 1. Effect of object size. J Comput Assist Tomogr. 1979;3:299-308.
28. Chetelat G, Landeau B, Eustache F, et al. Using voxel-based morphometry to map the structural changes associated with rapid conversion in MCI: a longitudinal MRI study. Neuroimage. 2005;27:934-946.
29. Meltzer CC, Zubieta JK, Brandt J, Tune LE, Mayberg HS, Frost JJ. Regional hypometabolism in Alzheimer's disease as measured by positron emission tomography after correction for effects of partial volume averaging. Neurology. 1996;47:454-461.
30. Muller-Gartner HW, Links JM, Prince JL, et al. Measurement of radiotracer concentration in brain gray matter using positron emission tomography: MRI-based correction for partial volume effects. J Cereb Blood Flow Metab. 1992;12:571-583.
31. Meltzer CC, Kinahan PE, Greer PJ, et al. Comparative evaluation of MR-based partial-volume correction schemes for PET. J Nucl Med. 1999;40:2053-2065.
32. Mazziotta JC, Toga AW, Evans A, Fox P, Lancaster J. A probabilistic atlas of the human brain: theory and rationale for its development. The International Consortium for Brain Mapping (ICBM). Neuroimage. 1995;2:89-101.
33. Mazziotta J, Toga A, Evans A, et al. A probabilistic atlas and reference system for the human brain. International Consortium for Brain Mapping (ICBM). Philos Trans R Soc Lond B Biol Sci. 2001;356:1293-1322.
34. Royall DR, Gao JH, Kellogg DL Jr. Insular Alzheimer's disease pathology as a cause of "age-related" autonomic dysfunction and mortality in the nondemented elderly. Med Hypotheses. 2006;67:747-758.
35. Foundas AL, Eure KF, Seltzer B. Conventional MRI volumetric measures of parietal and insular cortex in Alzheimer's disease. Prog Neuropsychopharmacol Biol Psychiatry. 1996;20:1131-1144.
36. Mosconi L, Tsui WH, De Santi S, et al. Reduced hippocampal metabolism in MCI and AD: automated FDG-PET image analysis. Neurology. 2005;64:1860-1867.
37. Rusjan P, Mamo D, Ginovart N, et al. An automated method for the extraction of regional data from PET images. Psychiatry Res. 2006;147:79-89.
38. 11C]PIB uptake is increased in mild cognitive impairment. Neurology. 2007;68:1603-1606.