Toxoplasma gondii Hsp20 is a stripe-arranged chaperone-like protein associated with the outer leaflet of the inner membrane complex

Biology of the Cell

Volumn 100, Issue 8, 2008, Pages 479-489

  de Miguel, Natalia ^a   Lebrun, Maryse ^b   Heaslip, Aoife ^c   Hu, Ke ^d   Beckers, Con J ^e   Matrajt, Mariana ^c   Dubremetz, Jean F ^b   Angel, Sergio O ^a  

^a INSTITUTO DE INVESTIGACIONES BIOTECNOLÓGICAS   (Argentina)

^b UNIVERSITÉ DE MONTPELLIER   (France)

^c UNIVERSITY OF VERMONT COLLEGE OF MEDICINE   (United States)

^d INDIANA UNIVERSITY   (United States)

^e UNIVERSITY OF NORTH CAROLINA   (United States)

Author keywords

Chaperone; Gliding associated protein; Inner membrane complex; Small heat shock protein (sHsp); Toxoplasma gondii; Transfection

Indexed keywords

CELL PROTEIN; CHAPERONE; GLIDING ASSOCIATED PROTEIN 45; HEAT SHOCK PROTEIN 20; INNER MEMBRANE COMPLEX 1 PROTEIN; INNER MEMBRANE COMPLEX PROTEIN; MEMBRANE PROTEIN; PHOSPHATIDYLINOSITOL 4 PHOSPHATE; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE PHOSPHOLIPID; PHOSPHOLIPID;

ARTICLE; CELL MEMBRANE; CONTROLLED STUDY; ELECTRON MICROSCOPY; FLUORESCENCE MICROSCOPY; MEMBRANE LEAFLET; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; TACHYZOITE; TOXOPLASMA GONDII;

ANIMALS; CELLULAR STRUCTURES; ELECTROPORATION; FLUORESCENT ANTIBODY TECHNIQUE; HSP20 HEAT-SHOCK PROTEINS; MEMBRANES; MOLECULAR CHAPERONES; PHOSPHOLIPIDS; PROTOZOAN PROTEINS; TOXOPLASMA;

TOXOPLASMA GONDII;

EID: 48749099075     PISSN: 02484900     EISSN: None     Source Type: Journal    
DOI: 10.1042/BC20080004     Document Type: Article

References (40)

1. Arrigo, A.P. (2005) In search of the molecular mechanism by which small stress proteins counteract apoptosis during cellular differentiation. J. Cell. Biochem. 94, 241-246
2. Achbarou, A., Mercereau-Puijalon, O., Autheman, J.M., Fortier, B., Camus, D. and Dubremetz, J. F. (1991) Characterization of microneme proteins of Toxoplasma gondii. Mol. Biochem. Parasitol. 47, 223-233
3. Bastin, P., Bagherzadeh, Z., Matthews, K.R. and Gull, K. (1996) A novel epitope tag system to study protein targeting and organelle biogenesis in Trypanosoma brucei. Mol. Biochem. Parasitol. 77, 235-239
4. Cerede, O., Dubremetz, J.F., Soete, M., Deslee, D., Vial, H., Bout, D. and Lebrun, M. (2005) Synergistic role of micronemal proteins in Toxoplasma gondii virulence. J. Exp. Med. 201, 453-463
5. Cobb, B.A. and Petrash, J.M. (2000) Structural and functional changes in the alpha A-crystallin R116C mutant in hereditary cataracts. Biochemistry 39, 15791-15798
6. Coppens, I. (2006) Contribution of host lipids to Toxoplasma pathogenesis. Cell. Microbiol. 8, 1-9
7. Coucheney, F., Gal, L., Beney, L., Lherminier, J., Gervais, P. and Guzzo, J. (2005) A small HSP, Lo18, interacts with the cell membrane and modulates lipid physical state under heat shock conditions in a lactic acid bacterium. Biochim. Biophys. Acta 1720, 92-98
8. De Matteis, M.A. and Godi, A. (2004a) PI-loting membrane traffic. Nat. Cell Biol. 6, 487-492
9. De Matteis, M.A. and Godi, A. (2004b) Protein-lipid interactions in membrane trafficking at the Golgi complex. Biochim. Biophys. Acta 1666, 264-274
10. de Miguel, N., Echeverria, P.C. and Angel, S.O. (2005) Differential subcellular localization of members of the Toxoplasma gondii small heat shock protein family. Eukaryot. Cell 4, 1990-1997
11. Dobrowolski, J.M. and Sibley, L.D. (1996) Toxoplasma invasion of mammalian cells is powered by the actin cytoskeleton of the parasite. Cell 84, 933-939
12. Dobrowolski, J.M., Niesman, I.R. and Sibley, L.D. (1997) Actin in the parasite Toxoplasma gondii is encoded by a single copy gene, ACT1 and exists primarily in a globular form. Cell. Motil. Cytoskeleton 37, 253-262
13. Foussard, F., Leriche, M.A. and Dubremetz, J.F. (1991) Characterization of the lipid content of Toxoplasma gondii rhoptries. Parasitology 102, 367-370
14. Garrido, C., Gurbuxani, S., Ravagnan, L. and Kroemer, G. (2001) Heat shock proteins: endogenous modulators of apoptotic cell death. Biochem. Biophys. Res. Commun. 286, 433-442
15. Gaskins, E., Gilk, S., DeVore, N., Mann, T., Ward, G. and Beckers, C. (2004) Identification of the membrane receptor of a class XIV myosin in Toxoplasma gondii. J. Cell Biol. 165, 383-393
16. 125I]iodonaphthalene-1-azide. Eukaryot. Cell 5, 1622-1634
17. Gubbels, M.J., Wieffer, M. and Striepen, B. (2004) Fluorescent protein tagging in Toxoplasma gondii: identification of a novel inner membrane complex component conserved among Apicomplexa. Mol. Biochem. Parasitol. 137, 99-110
18. Gupta, N., Zahn, M.M., Coppens, I., Joiner, K.A. and Voelker, D.R. (2005) Selective disruption of phosphatidylcholine metabolism of the intracellular parasite Toxoplasma gondii arrests its growth. J. Biol. Chem. 280, 16345-16353
19. Gusev, N.B., Bogatcheva, N.V. and Marston, S.B. (2002) Structure and properties of small heat shock proteins (sHsp) and their interaction with cytoskeleton proteins. Biochemistry (Moscow) 67, 511-519
20. Hanada, K., Kumagai, K., Yasuda, S., Miura, Y., Kawano, M., Fukasawa, M. and Nishijima, M. (2003) Molecular machinery for non-vesicular trafficking of ceramide. Nature 426, 803-809
21. Haslbeck, M., Franzmann, T., Weinfurtner, D. and Buchner, J. (2005) Some like it hot: the structure and function of small heat-shock proteins. Nat. Struct. Mol. Biol. 12, 842-846
22. Hu, K., Mann, T., Striepen, B., Beckers, C.J., Roos, D.S. and Murray, J.M. (2002a) Daughter cell assembly in the protozoan parasite Toxoplasma gondii. Mol. Biol. Cell 13, 593-606
23. Hu, K., Roos, D.S. and Murray, J.M. (2002b) A novel polymer of tubulin forms the conoid of Toxoplasma gondii. J. Cell Biol. 156, 1039-1050
24. Johnson, T.M., Rajfur, Z., Jacobson, K. and Beckers, C.J. (2007) Immobilization of the typeXIV myosin complex in Toxoplasma gondii. Mol. Biol. Cell 18, 3039-3046
25. Mann, T. and Beckers, C. (2001) Characterization of the subpellicular network, a filamentous membrane skeletal component in the parasite Toxoplasma gondii. Mol. Biochem. Parasitol. 115, 257-268
26. Mann, T., Gaskins, E. and Beckers, C. (2002) Proteolytic processing of TgIMC1 during maturation of the membrane skeleton of Toxoplasma gondii. J. Biol. Chem. 277, 41240-41246
27. Meissner, M., Schluter, D. and Soldati, D. (2002) Role of Toxoplasma gondii myosin A in powering parasite gliding and host cell invasion. Science 298, 837-840
28. Michell, R.H., Heath, V.L., Lemmon, M.A. and Dove, S.K. (2006) Phosphatidylinositol 3,5-bisphosphate: metabolism and cellular functions. Trends Biochem. Sci. 31, 52-63
29. Morrissette, N.S., Murray, J.M. and Roos, D.S. (1997) Subpellicular microtubules associate with an intramembranous particle lattice in the protozoan parasite Toxoplasma gondfii. J. Cell Sci. 110, 35-42
30. Nakamoto, H. and Vigh, L. (2007) The small heat shock proteins and their clients. Cell. Mol. Life Sci. 64, 294-306
31. Parcellier, A., Gurbuxani, S., Schmitt, E., Solary, E. and Garrido, C. (2003) Heat shock proteins, cellular chaperones that modulate mitochondrial cell death pathways. Biochem. Biophys. Res. Commun. 304, 505-512
32. Patron, S.A., Mondragon, M., González, S., Ambrosio, J.R., Guerrero, B.A.L. and Mondragon, R. (2005) Identification and purification of actin from the subpellicular network of Toxoplasma gondii tachyzoites. Int. J. Parasitol. 35, 883-894
33. Porchet, E. and Torpier, G. (1977) Freeze fracture study of Toxoplasma and Sarcocystis infective stages. Z. Parasitenkd. 54, 101-124
34. Raiborg, C., Rusten, T.E. and Stenmark, H. (2003) Protein sorting into multivesicular enclosomes. Curr. Opin. Cell Biol. 15, 446-455
35. Roth, M.G. (2004) Phosphoinositides in constitutive membrane traffic. Physiol. Rev. 84, 699-730
36. Torok, Z., Goloubinoff, R, Horvath, I., Tsvetkova, N.M., Glatz, A., Balogh, G., Varvasovszki, V., Los, D.A., Vierling, E., Crowe, J.H. and Vigh, L. (2001) Synechocystis HSP17 is an amphitropic protein that stabilizes heat-stressed membranes and binds denatured proteins for subsequent chaperone-mediated refolding. Proc. Natl. Acad. Sci. U.S.A. 98, 3098-3103
37. Tsvetkova, N.M., Horvath, I., Torok, Z., Wolkers, W.F., Balogi, Z., Shigapova, N., Crowe, L.M., Tablin, F., Vierling, E., Crowe, J.H. and Vigh, L. (2002) Small heat-shock proteins regulate membrane lipid polymorphism. Proc. Natl. Acad. Sci. U.S.A. 99, 13504-13509
38. van der, Z.E. and Piekarski, G. (1967) Endodyogeny in Toxoplasma gondii: a morphological analysis. Z. Parasitenkd. 29, 15-35
39. Vivier, E. and Petitprez, A. (1969) The outer membrane complex and its development at the time of the formation of daughter cells in Toxoplasma gondii. J. Cell Biol. 43, 329-342
40. Yamashita, S., Oku, M., Wasada, Y., Ano, Y. and Sakai, Y. (2006) P14P-signaling pathway for the synthesis of a nascent membrane structure in selective autophagy. J. Cell Biol. 173, 709-717