A Molecular Program for Contralateral Trajectory: Rig-1 Control by LIM Homeodomain Transcription Factors

Neuron

Volumn 59, Issue 3, 2008, Pages 413-424

  Wilson, Sara I ^a   Shafer, Beth ^a   Lee, Kevin J ^a   Dodd, Jane ^a  

^a Och Spine at New York Presbyterian Hospitals   (United States)

Author keywords

DEVBIO; MOLNEURO

Indexed keywords

RETINOIC ACID INDUCIBLE PROTEIN I; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR LHX2; TRANSCRIPTION FACTOR LHX9;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; BRAIN COMMISSURE; MOUSE; NERVE CELL; NERVE FIBER; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; RIG 1 GENE; TRANSCRIPTION REGULATION;

AFFERENT PATHWAYS; ANIMALS; AXONS; DEAD-BOX RNA HELICASES; EMBRYO, MAMMALIAN; FUNCTIONAL LATERALITY; GENE EXPRESSION REGULATION; GREEN FLUORESCENT PROTEINS; HOMEODOMAIN PROTEINS; MICE; MICE, TRANSGENIC; MODELS, NEUROLOGICAL; NERVE TISSUE PROTEINS; NEURONS, AFFERENT; SPINAL CORD; TRANSCRIPTION FACTORS;

EID: 48749088471     PISSN: 08966273     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuron.2008.07.020     Document Type: Article

References (57)

1. Affolter M., Slattery M., and Mann R.S. A lexicon for homeodomain-DNA recognition. Cell 133 (2008) 1133-1135
2. Augsburger A., Schuchardt A., Hoskins S., Dodd J., and Butler S. BMPs as mediators of roof plate repulsion of commissural neurons. Neuron 24 (1999) 127-141
3. Berger M.F., Badis G., Gehrke A.R., Talukder S., Philippakis A.A., Pena-Castillo L., Alleyne T.M., Mnaimneh S., Botvinnik O.B., Chan E.T., et al. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133 (2008) 1266-1276
4. Bermingham N.A., Hassan B.A., Wang V.Y., Fernandez M., Banfi S., Bellen H.J., Fritzsch B., and Zoghbi H.Y. Proprioceptor pathway development is dependent on Math1. Neuron 30 (2001) 411-422
5. Birk O.S., Casiano D.E., Wassif C.A., Cogliati T., Zhao L., Zhao Y., Grinberg A., Huang S., Kreidberg J.A., Parker K.L., et al. The LIM homeobox gene Lhx9 is essential for mouse gonad formation. Nature 403 (2000) 909-913
6. Brown A.G. Organization in the Spinal Cord (1981), Spinger- Verlag, Berlin, Heidelberg, New York
7. Bulfone A., Menguzzato E., Broccoli V., Marchitiello A., Gattuso C., Mariani M., Consalez G.G., Martinez S., Ballabio A., and Banfi S. Barhl1, a gene belonging to a new subfamily of mammalian homeobox genes, is expressed in migrating neurons of the CNS. Hum. Mol. Genet. 9 (2000) 1443-1452
8. Butler S.J., and Dodd J. A role for BMP heterodimers in roof plate-mediated repulsion of commissural axons. Neuron 38 (2003) 389-401
9. Butler S.J., and Tear G. Getting axons onto the right path: the role of transcription factors in axon guidance. Development 134 (2007) 439-448
10. Charron F., Stein E., Jeong J., McMahon A.P., and Tessier-Lavigne M. The morphogen sonic hedgehog is an axonal chemoattractant that collaborates with netrin-1 in midline axon guidance. Cell 113 (2003) 11-23
11. Chen Z., Gore B.B., Long H., Ma L., and Tessier-Lavigne M. Alternative splicing of the Robo3 axon guidance receptor governs the midline switch from attraction to repulsion. Neuron 58 (2008) 325-332
12. Cirulli V., and Yebra M. Netrins: beyond the brain. Nat. Rev. Mol. Cell Biol. 8 (2007) 296-306
13. Crowner D., Madden K., Goeke S., and Giniger E. Lola regulates midline crossing of CNS axons in Drosophila. Development 129 (2002) 1317-1325
14. Dasen J.S., Tice B.C., Brenner-Morton S., and Jessell T.M. A Hox regulatory network establishes motor neuron pool identity and target-muscle connectivity. Cell 123 (2005) 477-491
15. Del Barrio M.G., Taveira-Marques R., Muroyama Y., Yuk D.I., Li S., Wines-Samuelson M., Shen J., Smith H.K., Xiang M., Rowitch D., and Richardson W.D. A regulatory network involving Foxn4, Mash1 and delta-like 4/Notch1 generates V2a and V2b spinal interneurons from a common progenitor pool. Development 134 (2007) 3427-3436
16. Dickson B.J., and Gilestro G.F. Regulation of commissural axon pathfinding by slit and its Robo receptors. Annu. Rev. Cell Dev. Biol. 22 (2006) 651-675
17. Fazeli A., Dickinson S.L., Hermiston M.L., Tighe R.V., Steen R.G., Small C.G., Stoeckli E.T., Keino-Masu K., Masu M., Rayburn H., et al. Phenotype of mice lacking functional Deleted in colorectal cancer (Dcc) gene. Nature 386 (1997) 796-804
18. Garcia-Frigola C., Carreres M.I., Vegar C., Mason C., and Herrera E. Zic2 promotes axonal divergence at the optic chiasm midline by EphB1-dependent and -independent mechanisms. Development 135 (2008) 1833-1841
19. Geisen M.J., Meglio T.D., Pasqualetti M., Ducret S., Brunet J.F., Chedotal A., and Rijli F.M. Hox Paralog Group 2 Genes Control the Migration of Mouse Pontine Neurons through Slit-Robo Signaling. PLoS Biol. 6 (2008) e142 10.1371/journal.pbio.0060142
20. German M.S., Moss L.G., Wang J., and Rutter W.J. The insulin and islet amyloid polypeptide genes contain similar cell-specific promoter elements that bind identical beta-cell nuclear complexes. Mol. Cell. Biol. 12 (1992) 1777-1788
21. German M.S., Wang J., Chadwick R.B., and Rutter W.J. Synergistic activation of the insulin gene by a LIM-homeo domain protein and a basic helix-loop-helix protein: building a functional insulin minienhancer complex. Genes Dev. 6 (1992) 2165-2176
22. Goulding M., Lanuza G., Sapir T., and Narayan S. The formation of sensorimotor circuits. Curr. Opin. Neurobiol. 12 (2002) 508-515
23. Gowan K., Helms A.W., Hunsaker T.L., Collisson T., Ebert P.J., Odom R., and Johnson J.E. Crossinhibitory activities of Ngn1 and Math1 allow specification of distinct dorsal interneurons. Neuron 31 (2001) 219-232
24. Gross M.K., Dottori M., and Goulding M. Lbx1 specifies somatosensory association interneurons in the dorsal spinal cord. Neuron 34 (2002) 535-549
25. Helms A.W., and Johnson J.E. Progenitors of dorsal commissural interneurons are defined by MATH1 expression. Development 125 (1998) 919-928
26. Helms A.W., and Johnson J.E. Specification of dorsal spinal cord interneurons. Curr. Opin. Neurobiol. 13 (2003) 42-49
27. Hsiau T.H., Diaconu C., Myers C.A., Lee J., Cepko C.L., and Corbo J.C. The cis-regulatory logic of the mammalian photoreceptor transcriptional network. PLoS ONE 2 (2007) e643 10.1371/journal.pone.0000643
28. Kania A., and Jessell T.M. Topographic motor projections in the limb imposed by LIM homeodomain protein regulation of ephrin-A:EphA interactions. Neuron 38 (2003) 581-596
29. Karlsson O., Thor S., Norberg T., Ohlsson H., and Edlund T. Insulin gene enhancer binding protein Isl-1 is a member of a novel class of proteins containing both a homeo- and a Cys-His domain. Nature 344 (1990) 879-882
30. Keino-Masu K., Masu M., Hinck L., Leonardo E.D., Chan S.S., Culotti J.G., and Tessier-Lavigne M. Deleted in Colorectal Cancer (DCC) encodes a netrin receptor. Cell 87 (1996) 175-185
31. Kennedy T.E., Serafini T., de la Torre J.R., and Tessier-Lavigne M. Netrins are diffusible chemotropic factors for commissural axons in the embryonic spinal cord. Cell 78 (1994) 425-435
32. Kobayashi Y. Distribution and morphology of spinothalamic tract neurons in the rat. Anat. Embryol. (Berl.) 197 (1998) 51-67
33. Labrador J.P., O'Keefe D., Yoshikawa S., McKinnon R.D., Thomas J.B., and Bashaw G.J. The homeobox transcription factor even-skipped regulates netrin-receptor expression to control dorsal motor-axon projections in Drosophila. Curr. Biol. 15 (2005) 1413-1419
34. Lee K.J., Mendelsohn M., and Jessell T.M. Neuronal patterning by BMPs: a requirement for GDF7 in the generation of a discrete class of commissural interneurons in the mouse spinal cord. Genes Dev. 12 (1998) 3394-3407
35. Lee R., Petros T.J., and Mason C.A. Zic2 regulates retinal ganglion cell axon avoidance of ephrinB2 through inducing expression of the guidance receptor EphB1. J. Neurosci. 28 (2008) 5910-5919
36. Light A.R. Normal anatomy and physiology of the spinal cord dorsal horn. Appl. Neurophysiol. 51 (1988) 78-88
37. Logan C., Wizenmann A., Drescher U., Monschau B., Bonhoeffer F., and Lumsden A. Rostral optic tectum acquires caudal characteristics following ectopic engrailed expression. Curr. Biol. 6 (1996) 1006-1014
38. Lumpkin E.A., Collisson T., Parab P., Omer-Abdalla A., Haeberle H., Chen P., Doetzlhofer A., White P., Groves A., Segil N., and Johnson J.E. Math1-driven GFP expression in the developing nervous system of transgenic mice. Gene Expr. Patterns 3 (2003) 389-395
39. Lyuksyutova A.I., Lu C.C., Milanesio N., King L.A., Guo N., Wang Y., Nathans J., Tessier-Lavigne M., and Zou Y. Anterior-posterior guidance of commissural axons by Wnt-frizzled signaling. Science 302 (2003) 1984-1988
40. Muller T., Brohmann H., Pierani A., Heppenstall P.A., Lewin G.R., Jessell T.M., and Birchmeier C. The homeodomain factor lbx1 distinguishes two major programs of neuronal differentiation in the dorsal spinal cord. Neuron 34 (2002) 551-562
41. Noyes M.B., Christensen R.G., Wakabayashi A., Stormo G.D., Brodsky M.H., and Wolfe S.A. Analysis of homeodomain specificities allows the family-wide prediction of preferred recognition sites. Cell 133 (2008) 1277-1289
42. Peng C.Y., Yajima H., Burns C.E., Zon L.I., Sisodia S.S., Pfaff S.L., and Sharma K. Notch and MAML signaling drives Scl-dependent interneuron diversity in the spinal cord. Neuron 53 (2007) 813-827
43. Polleux F., Ince-Dunn G., and Ghosh A. Transcriptional regulation of vertebrate axon guidance and synapse formation. Nat. Rev. Neurosci. 8 (2007) 331-340
44. Porter F.D., Drago J., Xu Y., Cheema S.S., Wassif C., Huang S.P., Lee E., Grinberg A., Massalas J.S., Bodine D., et al. Lhx2, a LIM homeobox gene, is required for eye, forebrain, and definitive erythrocyte development. Development 124 (1997) 2935-2944
45. Rincon-Limas D.E., Lu C.H., Canal I., and Botas J. The level of DLDB/CHIP controls the activity of the LIM homeodomain protein apterous: evidence for a functional tetramer complex in vivo. EMBO J. 19 (2000) 2602-2614
46. Roberson M.S., Schoderbek W.E., Tremml G., and Maurer R.A. Activation of the glycoprotein hormone alpha-subunit promoter by a LIM-homeodomain transcription factor. Mol. Cell. Biol. 14 (1994) 2985-2993
47. Rohr C., Prestel J., Heidet L., Hosser H., Kriz W., Johnson R.L., Antignac C., and Witzgall R. The LIM-homeodomain transcription factor Lmx1b plays a crucial role in podocytes. J. Clin. Invest. 109 (2002) 1073-1082
48. Saba R., Nakatsuji N., and Saito T. Mammalian BarH1 confers commissural neuron identity on dorsal cells in the spinal cord. J. Neurosci. 23 (2003) 1987-1991
49. Saba R., Johnson J.E., and Saito T. Commissural neuron identity is specified by a homeodomain protein, Mbh1, that is directly downstream of Math1. Development 132 (2005) 2147-2155
50. Sabatier C., Plump A.S., Le M., Brose K., Tamada A., Murakami F., Lee E.Y., and Tessier-Lavigne M. The divergent Robo family protein rig-1/Robo3 is a negative regulator of slit responsiveness required for midline crossing by commissural axons. Cell 117 (2004) 157-169
51. Saha B., Hari P., Huilgol D., and Tole S. Dual role for LIM-homeodomain gene Lhx2 in the formation of the lateral olfactory tract. J. Neurosci. 27 (2007) 2290-2297
52. Saito T., Sawamoto K., Okano H., Anderson D.J., and Mikoshiba K. Mammalian BarH homologue is a potential regulator of neural bHLH genes. Dev. Biol. 199 (1998) 216-225
53. Serafini T., Colamarino S.A., Leonardo E.D., Wang H., Beddington R., Skarnes W.C., and Tessier-Lavigne M. Netrin-1 is required for commissural axon guidance in the developing vertebrate nervous system. Cell 87 (1996) 1001-1014
54. Seth A., Culverwell J., Walkowicz M., Toro S., Rick J.M., Neuhauss S.C., Varga Z.M., and Karlstrom R.O. belladonna/(Ihx2) is required for neural patterning and midline axon guidance in the zebrafish forebrain. Development 133 (2006) 725-735
55. Silos-Santiago I., and Snider W.D. Development of commissural neurons in the embryonic rat spinal cord. J. Comp. Neurol. 325 (1992) 514-526
56. Wang W., Mullikin-Kilpatrick D., Crandall J.E., Gronostajski R.M., Litwack E.D., and Kilpatrick D.L. Nuclear factor I coordinates multiple phases of cerebellar granule cell development via regulation of cell adhesion molecules. J. Neurosci. 27 (2007) 6115-6127
57. Wong K., Park H.T., Wu J.Y., and Rao Y. Slit proteins: molecular guidance cues for cells ranging from neurons to leukocytes. Curr. Opin. Genet. Dev. 12 (2002) 583-591