Immunosuppressant calcineurin inhibitors phase shift circadian rhythms and inhibit circadian responses to light

Pharmacology Biochemistry and Behavior

Volumn 90, Issue 4, 2008, Pages 763-768

  Katz, Marcelo E ^a   Simonetta, Sergio H ^a   Ralph, Martin R ^b   Golombek, Diego A ^a  

^a UNIVERSIDAD NACIONAL DE QUILMES   (Argentina)

^b UNIVERSITY OF TORONTO   (Canada)

Author keywords

Calcineurin; Circadian; Cyclosporin A; Entrainment; Tacrolimus

Indexed keywords

CALCINEURIN; CALCINEURIN INHIBITOR; CYCLOSPORIN A; DRUG VEHICLE; IMMUNOSUPPRESSIVE AGENT; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; PHOSPHATASE; TACROLIMUS;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CIRCADIAN RHYTHM; CONTINUOUS INFUSION; CONTROLLED STUDY; DOSE TIME EFFECT RELATION; DRUG DELIVERY SYSTEM; DRUG EFFICACY; DRUG MECHANISM; DRUG SAFETY; ENZYME INHIBITION; HAMSTER; LIGHT; LOCOMOTION; MALE; NEUROTRANSMISSION; NONHUMAN; OSMOTIC MINIPUMP; PHOTOSTIMULATION; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

ANIMALS; BLOTTING, WESTERN; BRAIN CHEMISTRY; CALCINEURIN; CIRCADIAN RHYTHM; CRICETINAE; CYCLOSPORINE; IMMUNOSUPPRESSIVE AGENTS; LIGHT; MESOCRICETUS; MOTOR ACTIVITY; SUPRACHIASMATIC NUCLEUS; TACROLIMUS;

MAMMALIA;

EID: 48749087338     PISSN: 00913057     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pbb.2008.05.017     Document Type: Article

References (40)

1. Agostino P.V., Ferreyra G.A., Murad A.D., Watanabe Y., and Golombek D.A. Diurnal, circadian and photic regulation of calcium/calmodulin-dependent kinase II and neuronal nitric oxide synthase in the hamster suprachiasmatic nuclei. Neurochem Int. 44 (2000) 617-625
2. Alagarsamy S., Saugstad J., Warren L., Mansuy I.M., Gereau IV R.W., and Conn P.J. NMDA-induced potentiation of mGluR5 is mediated by activation of protein phosphatase 2B/calcineurin. Neuropharmacology 49 Suppl 1 (2005) 135-145
3. Baraldo M., and Furlanut M. Chronopharmacokinetics of ciclosporin and tacrolimus. Clin Pharmacokinet. 45 (2006) 775-788
4. Cegielska A., Gietzen K.F., Rivers A., and Virshup D.M. Autoinhibition of casein kinase I epsilon (CKI epsilon) is relieved by protein phosphatases and limited proteolysis. J Biol Chem 273 (1998) 1357-1364
5. Cipolle R.J., Canafax D.M., Rabatin J., Bowers L.D., Sutherland D.E., and Hrushesky W.J. Time-dependent disposition of cyclosporine after pancreas transplantation, and application of chronopharmacokinetics to improve immunosuppression. Pharmacotherapy 8 (1998) 47-51
6. Curtis J.J. Hypertensinogenic mechanism of the calcineurin inhibitors. Curr. Hypertens Rep. 4 (2002) 377-380
7. Ding J.M., Buchanan G.F., Tischkau S.A., Chen D., Kuriashkina L., Faiman L.E., Alster J.M., McPherson P.S., Campbell K.P., and Gillette M.U. A neuronal ryanodine receptor mediates light-induced phase delays of the circadian clock. Nature 394 (1998) 381-384
8. Dunlap J.C. Molecular bases for circadian clocks. Cell 96 (1999) 271-290
9. Eide E.J., and Virshup D.M. Casein kinase I: another cog in the circadian clockworks. Chronobiol. Int. 18 (2001) 389-398
10. Eide E.J., Woolf M.F., Kang H., Woolf P., Hurst W., Camacho F., Vielhaber E.L., Giovanni A., and Virshup D.M. Control of mammalian circadian rhythm by CKIepsilon-regulated proteasome-mediated PER2 degradation. Mol. Cell Biol. 25 (2005) 2795-2807
11. 2+-calcineurin-NFAT cascade in cardiac myocytes. Cardiovasc. Res. 63 (2004) 450-457
12. 2+/calmodulin-dependent protein kinase II-dependent long-term potentiation in the rat suprachiasmatic nucleus and its inhibition by melatonin. J. Neurosci. Res. 70 (2002) 799-807
13. Galiatsou E., Morris S.T., Jardine A.G., Rodger R.S., Watson M.A., and Elliott H.L. Cardiac and vascular abnormalities in renal transplant patients: differential effects of cyclosporin and azathioprine. J. Nephrol. 13 (2000) 185-192
14. Golombek D.A., and Ralph M.R. Circadian responses to light: the calmodulin connection. Neurosci. Lett. 192 (1995) 101-104
15. Golombek D.A., Ferreyra G.A., Agostino P.V., Murad A.D., Rubio M.F., Pizzio G.A., Katz M.E., Marpegan L., and Bekinschtein T.A. From light to genes: moving the hands of the circadian clock. Front Biosci. 8 (2003) s285-s293
16. Iitaka C., Miyazaki K., Akaike T., and Ishida N. A role for glycogen synthase kinase-3beta in the mammalian circadian clock. J. Biol. Chem. 280 (2005) 29397-29402
17. Kemper M.J., Sparta G., Laube G.F., Miozzari M., and Neuhaus T.J. Neuropsychologic side-effects of tacrolimus in pediatric renal transplantation. Clin Transplant 17 (2003) 130-134
18. Klee C.B., Crouch T.H., and Krinks M.H. Calcineurin: a calcium- and calmodulin-binding protein of the nervous system. Proc. Natl. Acad. Sci. U. S. A. 76 (1979) 6270-6273
19. Klisch C., Mahr S., and Meissl H. Circadian activity rhythms and phase-shifting of cultured neurons of the rat suprachiasmatic nucleus. Chronobiol. Int. 23 (2006) 181-190
20. Koefoed-Nielsen P.B., Karamperis N., and Jørgensen K.A. 24-h monitoring of calcineurin phosphatase activity in healthy subjects. Scand. J. Immunol. 62 (2005) 309-311
21. Kooman J.P., Christiaans M.H., Boots J.M., van Der Sande F.M., Leunissen K.M., and van Hooff J.P. A comparison between office and ambulatory blood pressure measurements in renal transplant patients with chronic transplant nephropathy. Am. J. Kidney Dis. 37 (2001) 1170-1176
22. Lipkin G.W., Tucker B., Giles M., and Raine A.E. Ambulatory blood pressure and left ventricular mass in cyclosporin- and non-cyclosporin-treated renal transplant recipients. J. Hypertens. 11 (1993) 439-442
23. Liu J., Farmer Jr. J.D., Lane W.S., Friedman J., Weissman I., and Schreiber S.L. Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes. Cell 66 (1991) 807-815
24. Liu F., Virshup D.M., Nairn A.C., and Greengard P. Mechanism of regulation of casein kinase I activity by group I metabotropic glutamate receptors. J. Biol. Chem. 277 (2002) 45393-45399
25. Lowrey P.L., Shimomura K., Antoch M.P., Yamazaki S., Zemenides P.D., Ralph M.R., Menaker M., and Takahashi J.S. Positional syntenic cloning and functional characterization of the mammalian circadian mutation tau. Science 288 (2000) 483-492
26. Malmary M.F., Kabbaj K., Labat C., Batalla A., Houti I., Moussamih S., and Oustrin J. Chronopharmacokinetics of cyclosporine A in the Wistar rat following oral administration. Eur. J. Drug Metab. Pharmacokinet. 17 (1992) 135-144
27. Mrosovsky N. Locomotor activity and non-photic influences on circadian clocks. Biol. Rev. Camb. Philos. Soc. 71 (1996) 343-372
28. Neuhaus P., McMaster P., Calne R., Pichlmayr R., Otto G., Williams R., Bismuth H., and Groth C. Neurological complications in the European multicentre study of FK 506 and cyclosporin in primary liver transplantation. Transpl. Int. 7 Suppl 1 (1994) S27-S31
29. Ohlman S., Lindholm A., Hagglund H., Sawe J., and Kahan B.D. On the intraindividual variability and chronobiology of cyclosporine pharmacokinetics in renal transplantation. Eur. J. Clin. Pharmacol. 44 (1993) 265-269
30. Panda S., Antoch M.P., Miller B.H., Su A.I., Schook A.B., Straume M., Schultz P.G., Kay S.A., Takahashi J.S., and Hogenesch J.B. Coordinated transcription of key pathways in the mouse by the circadian clock. Cell 109 (2002) 307-320
31. Reppert S.M., and Weaver D.R. Coordination of circadian timing in mammals. Nature 418 (2002) 935-941
32. Rusnak F., and Mertz P. Calcineurin: form and function. Physiol. Rev. 80 (2000) 1483-1521
33. Schreiber S.L., and Crabtree G.R. The mechanism of action of cyclosporin A and FK506. Immunol. Today 13 (1992) 136-142
34. Taler S.J., Textor S.C., Canzanello V.J., Wilson D.J., Wiesner R.H., and Krom R.A. Loss of nocturnal blood pressure fall after liver transplantation during immunosuppressive therapy. Am. J. Hypertens. 8 (1995) 598-605
35. van de Borne P., Gelin M., Van de Stadt J., and Degaute J.P. Circadian rhythms of blood pressure after liver transplantation. Hypertension 21 (1993) 398-405
36. van den Dorpel M.A., van den Meiracker A.H., Lameris T.W., Boomsma F., Levi M., Man in 't Veld A.J., Weimar W., and Schalekamp M.A. Cyclosporin A impairs the nocturnal blood pressure fall in renal transplant recipients. Hypertension 28 (1996) 304-307
37. Vielhaber E., Eide E., Rivers A., Gao Z.H., and Virshup D.M. Nuclear entry of the circadian regulator mPER1 is controlled by mammalian casein kinase I epsilon. Mol. Cell Biol. 20 (2000) 4888-4899
38. Welsh D.K., Logothetis D.E., Meister M., and Reppert S.M. Individual neurons dissociated from rat suprachiasmatic nucleus express independently phased circadian firing rhythms. Neuron 14 (1995) 697-706
39. Yannielli P.C., and Harrington M.E. Let there be "more" light: enhancement of light actions on the circadian system through non-photic pathways. Prog. Neurobiol. 74 (2004) 59-76
40. Yin L., Wang J., Klein P.S., and Lazar M.A. Nuclear receptor Rev-erbalpha is a critical lithium-sensitive component of the circadian clock. Science 311 (2006) 1002-1005