-
1
-
-
0028589378
-
Regulation of cell number in the mammalian gastrointestinal tract: the importance of apoptosis
-
Hall P.A., Coates P.J., Ansari B., et al. Regulation of cell number in the mammalian gastrointestinal tract: the importance of apoptosis. J Cell Sci 107 (1994) 3569-3577
-
(1994)
J Cell Sci
, vol.107
, pp. 3569-3577
-
-
Hall, P.A.1
Coates, P.J.2
Ansari, B.3
-
2
-
-
17744384002
-
Embryonic lethality and fetal liver apoptosis in mice lacking the c-raf-1 gene
-
Mikula M., Schreiber M., Husak Z., et al. Embryonic lethality and fetal liver apoptosis in mice lacking the c-raf-1 gene. EMBO J 20 (2001) 1952-1962
-
(2001)
EMBO J
, vol.20
, pp. 1952-1962
-
-
Mikula, M.1
Schreiber, M.2
Husak, Z.3
-
3
-
-
33745608974
-
A balance between Raf-1 and Fas expression sets the pace of erythroid differentiation
-
Rubiolo C., Piazzolla D., Meissl K., et al. A balance between Raf-1 and Fas expression sets the pace of erythroid differentiation. Blood 108 (2006) 152-159
-
(2006)
Blood
, vol.108
, pp. 152-159
-
-
Rubiolo, C.1
Piazzolla, D.2
Meissl, K.3
-
4
-
-
0035808788
-
Protective role of Raf-1 in Salmonella-induced macrophage apoptosis
-
Jesenberger V., Procyk K.J., Ruth J., et al. Protective role of Raf-1 in Salmonella-induced macrophage apoptosis. J Exp Med 193 (2001) 353-364
-
(2001)
J Exp Med
, vol.193
, pp. 353-364
-
-
Jesenberger, V.1
Procyk, K.J.2
Ruth, J.3
-
5
-
-
9644295769
-
Cardiac-specific disruption of the c-raf-1 gene induces cardiac dysfunction and apoptosis
-
Yamaguchi O., Watanabe T., Nishida K., et al. Cardiac-specific disruption of the c-raf-1 gene induces cardiac dysfunction and apoptosis. J Clin Invest 114 (2004) 937-943
-
(2004)
J Clin Invest
, vol.114
, pp. 937-943
-
-
Yamaguchi, O.1
Watanabe, T.2
Nishida, K.3
-
6
-
-
0029813545
-
Enterocolitis and colon cancer in interleukin-10-deficient mice are associated with aberrant cytokine production and CD4(+) TH1-like responses
-
Berg D.J., Davidson N., Kuhn R., et al. Enterocolitis and colon cancer in interleukin-10-deficient mice are associated with aberrant cytokine production and CD4(+) TH1-like responses. J Clin Invest 98 (1996) 1010-1020
-
(1996)
J Clin Invest
, vol.98
, pp. 1010-1020
-
-
Berg, D.J.1
Davidson, N.2
Kuhn, R.3
-
7
-
-
15244361961
-
Kinase suppressor of Ras-1 protects intestinal epithelium from cytokine-mediated apoptosis during inflammation
-
Yan F., John S.K., Wilson G., et al. Kinase suppressor of Ras-1 protects intestinal epithelium from cytokine-mediated apoptosis during inflammation. J Clin Invest 114 (2004) 1272-1280
-
(2004)
J Clin Invest
, vol.114
, pp. 1272-1280
-
-
Yan, F.1
John, S.K.2
Wilson, G.3
-
8
-
-
0025181580
-
A novel method in the induction of reliable experimental acute and chronic ulcerative colitis in mice
-
Okayasu I., Hatakeyama S., Yamada M., et al. A novel method in the induction of reliable experimental acute and chronic ulcerative colitis in mice. Gastroenterology 98 (1990) 694-702
-
(1990)
Gastroenterology
, vol.98
, pp. 694-702
-
-
Okayasu, I.1
Hatakeyama, S.2
Yamada, M.3
-
9
-
-
0027224059
-
Clinicopathologic study of dextran sulfate sodium experimental murine colitis
-
Cooper H., Murthy S., Shah R., et al. Clinicopathologic study of dextran sulfate sodium experimental murine colitis. Lab Invest 69 (1993) 238-249
-
(1993)
Lab Invest
, vol.69
, pp. 238-249
-
-
Cooper, H.1
Murthy, S.2
Shah, R.3
-
10
-
-
0032617059
-
Tissue distribution of dextran sulfate sodium (DSS) in the acute phase of murine DSS-induced colitis
-
Kitajima S., Takuma S., and Morimoto M. Tissue distribution of dextran sulfate sodium (DSS) in the acute phase of murine DSS-induced colitis. J Vet Med Sci 61 (1999) 67-70
-
(1999)
J Vet Med Sci
, vol.61
, pp. 67-70
-
-
Kitajima, S.1
Takuma, S.2
Morimoto, M.3
-
11
-
-
0031736096
-
Chronic experimental colitis induced by dextran sulphate sodium (DSS) is characterized by Th1 and Th2 cytokines
-
Dieleman L.A., Palmen M.J., Akol H., et al. Chronic experimental colitis induced by dextran sulphate sodium (DSS) is characterized by Th1 and Th2 cytokines. Clin Exp Immunol 114 (1998) 385-391
-
(1998)
Clin Exp Immunol
, vol.114
, pp. 385-391
-
-
Dieleman, L.A.1
Palmen, M.J.2
Akol, H.3
-
12
-
-
0033768784
-
Characterisation of acute murine dextran sodium sulphate colitis: cytokine profile and dose dependency
-
Egger B., Bajaj-Elliott M., MacDonald T.T., et al. Characterisation of acute murine dextran sodium sulphate colitis: cytokine profile and dose dependency. Digestion 62 (2000) 240-248
-
(2000)
Digestion
, vol.62
, pp. 240-248
-
-
Egger, B.1
Bajaj-Elliott, M.2
MacDonald, T.T.3
-
13
-
-
34247235029
-
Toll-like receptor 2 controls mucosal inflammation by regulating epithelial barrier function
-
Cario E., Gerken G., and Podolsky D.K. Toll-like receptor 2 controls mucosal inflammation by regulating epithelial barrier function. Gastroenterology 132 (2007) 1359-1374
-
(2007)
Gastroenterology
, vol.132
, pp. 1359-1374
-
-
Cario, E.1
Gerken, G.2
Podolsky, D.K.3
-
14
-
-
20244372724
-
Toll-like receptor-4 is required for intestinal response to epithelial injury and limiting bacterial translocation in a murine model of acute colitis
-
Fukata M., Michelsen K.S., Eri R., et al. Toll-like receptor-4 is required for intestinal response to epithelial injury and limiting bacterial translocation in a murine model of acute colitis. Am J Physiol Gastrointest Liver Physiol 288 (2005) G1055-G1065
-
(2005)
Am J Physiol Gastrointest Liver Physiol
, vol.288
-
-
Fukata, M.1
Michelsen, K.S.2
Eri, R.3
-
15
-
-
33748271299
-
Cox-2 is regulated by Toll-like receptor-4 (TLR4) signaling: role in proliferation and apoptosis in the intestine
-
Fukata M., Chen A., Klepper A., et al. Cox-2 is regulated by Toll-like receptor-4 (TLR4) signaling: role in proliferation and apoptosis in the intestine. Gastroenterology 131 (2006) 862-877
-
(2006)
Gastroenterology
, vol.131
, pp. 862-877
-
-
Fukata, M.1
Chen, A.2
Klepper, A.3
-
16
-
-
4043059169
-
Tissue-specific and inducible Cre-mediated recombination in the gut epithelium
-
el Marjou F., Janssen K.P., Chang B.H., et al. Tissue-specific and inducible Cre-mediated recombination in the gut epithelium. Genesis 39 (2004) 186-193
-
(2004)
Genesis
, vol.39
, pp. 186-193
-
-
el Marjou, F.1
Janssen, K.P.2
Chang, B.H.3
-
17
-
-
0028849048
-
Shc is a substrate of the rat intestinal epidermal growth factor receptor tyrosine kinase
-
Polk D.B. Shc is a substrate of the rat intestinal epidermal growth factor receptor tyrosine kinase. Gastroenterology 109 (1995) 1845-1851
-
(1995)
Gastroenterology
, vol.109
, pp. 1845-1851
-
-
Polk, D.B.1
-
18
-
-
0031936080
-
Epidermal growth factor receptor-stimulated intestinal epithelial cell migration requires phospholipase C activity
-
Polk D.B. Epidermal growth factor receptor-stimulated intestinal epithelial cell migration requires phospholipase C activity. Gastroenterology 117 (1998) 493-502
-
(1998)
Gastroenterology
, vol.117
, pp. 493-502
-
-
Polk, D.B.1
-
19
-
-
0027498506
-
Establishment of conditionally immortalized epithelial cell lines from both colon and small intestine of adult H-2Kb-tsA58 transgenic mice
-
Whitehead R.H., VanEeden P.E., Noble M.D., et al. Establishment of conditionally immortalized epithelial cell lines from both colon and small intestine of adult H-2Kb-tsA58 transgenic mice. Proc Natl Acad Sci U S A 90 (1993) 587-591
-
(1993)
Proc Natl Acad Sci U S A
, vol.90
, pp. 587-591
-
-
Whitehead, R.H.1
VanEeden, P.E.2
Noble, M.D.3
-
21
-
-
20444411532
-
Second nature: biological functions of the Raf-1 "kinase."
-
Baccarini M. Second nature: biological functions of the Raf-1 "kinase.". FEBS Lett 579 (2005) 3271-3277
-
(2005)
FEBS Lett
, vol.579
, pp. 3271-3277
-
-
Baccarini, M.1
-
22
-
-
23244455992
-
Interleukin-13 is the key effector Th2 cytokine in ulcerative colitis that affects epithelial tight junctions, apoptosis, and cell restitution
-
Heller F., Florian P., Bojarski C., et al. Interleukin-13 is the key effector Th2 cytokine in ulcerative colitis that affects epithelial tight junctions, apoptosis, and cell restitution. Gastroenterology 129 (2005) 550-564
-
(2005)
Gastroenterology
, vol.129
, pp. 550-564
-
-
Heller, F.1
Florian, P.2
Bojarski, C.3
-
23
-
-
0033563648
-
Conversion of TNF-α from antiproliferative to proliferative ligand in mouse intestinal epithelial cells by regulating mitogen-activated protein kinase
-
Kaiser G.C., Yan F., and Polk D.B. Conversion of TNF-α from antiproliferative to proliferative ligand in mouse intestinal epithelial cells by regulating mitogen-activated protein kinase. Exp Cell Res 249 (1999) 349-358
-
(1999)
Exp Cell Res
, vol.249
, pp. 349-358
-
-
Kaiser, G.C.1
Yan, F.2
Polk, D.B.3
-
24
-
-
21744432476
-
AMP-18 protects barrier function of colonic epithelial cells: role of tight junction proteins
-
Walsh-Reitz M.M., Huang E.F., Musch M.W., et al. AMP-18 protects barrier function of colonic epithelial cells: role of tight junction proteins. Am J Physiol Gastrointest Liver Physiol 289 (2005) G163-G171
-
(2005)
Am J Physiol Gastrointest Liver Physiol
, vol.289
-
-
Walsh-Reitz, M.M.1
Huang, E.F.2
Musch, M.W.3
-
25
-
-
38349108166
-
Novel role of the vitamin D receptor in maintaining the integrity of the intestinal mucosal barrier
-
Kong J., Zhang Z., Musch M.W., et al. Novel role of the vitamin D receptor in maintaining the integrity of the intestinal mucosal barrier. Am J Physiol Gastrointest Liver Physiol 294 (2008) G208-G216
-
(2008)
Am J Physiol Gastrointest Liver Physiol
, vol.294
-
-
Kong, J.1
Zhang, Z.2
Musch, M.W.3
-
26
-
-
34447517213
-
Dextran sulfate sodium enhances interleukin-1 β release via activation of p38 MAPK and ERK1/2 pathways in murine peritoneal macrophages
-
Kwon K.H., Ohigashi H., and Murakami A. Dextran sulfate sodium enhances interleukin-1 β release via activation of p38 MAPK and ERK1/2 pathways in murine peritoneal macrophages. Life Sci 81 (2007) 362-371
-
(2007)
Life Sci
, vol.81
, pp. 362-371
-
-
Kwon, K.H.1
Ohigashi, H.2
Murakami, A.3
-
27
-
-
24744454380
-
Protein phosphatase 2A regulates apoptosis in intestinal epithelial cells
-
Ray R.M., Bhattacharya S., and Johnson L.R. Protein phosphatase 2A regulates apoptosis in intestinal epithelial cells. J Biol Chem 280 (2005) 31091-31100
-
(2005)
J Biol Chem
, vol.280
, pp. 31091-31100
-
-
Ray, R.M.1
Bhattacharya, S.2
Johnson, L.R.3
-
28
-
-
33846187694
-
ERK promotes hydrogen peroxide-induced apoptosis through caspase-3 activation and inhibition of Akt in renal epithelial cells
-
Zhuang S., Yan Y., Daubert R.A., et al. ERK promotes hydrogen peroxide-induced apoptosis through caspase-3 activation and inhibition of Akt in renal epithelial cells. Am J Physiol Renal Physiol 292 (2007) F440-F447
-
(2007)
Am J Physiol Renal Physiol
, vol.292
-
-
Zhuang, S.1
Yan, Y.2
Daubert, R.A.3
-
29
-
-
0037044748
-
Protein kinase C-α and ERK1/2 mediate mitochondrial dysfunction, decreases in active Na+ transport, and cisplatin-induced apoptosis in renal cells
-
Nowak G. Protein kinase C-α and ERK1/2 mediate mitochondrial dysfunction, decreases in active Na+ transport, and cisplatin-induced apoptosis in renal cells. J Biol Chem 277 (2002) 43377-43388
-
(2002)
J Biol Chem
, vol.277
, pp. 43377-43388
-
-
Nowak, G.1
-
30
-
-
0038814026
-
Uropathogenic Escherichia coli toxins induce caspase-independent apoptosis in renal proximal tubular cells via ERK signaling
-
Chen M., Jahnukainen T., Bao W., et al. Uropathogenic Escherichia coli toxins induce caspase-independent apoptosis in renal proximal tubular cells via ERK signaling. Am J Nephrol 23 (2003) 140-151
-
(2003)
Am J Nephrol
, vol.23
, pp. 140-151
-
-
Chen, M.1
Jahnukainen, T.2
Bao, W.3
-
31
-
-
12344324705
-
MEK inhibitor, U0126, attenuates cisplatin-induced renal injury by decreasing inflammation and apoptosis
-
Jo S.K., Cho W.Y., Sung S.A., et al. MEK inhibitor, U0126, attenuates cisplatin-induced renal injury by decreasing inflammation and apoptosis. Kidney Int 67 (2005) 458-466
-
(2005)
Kidney Int
, vol.67
, pp. 458-466
-
-
Jo, S.K.1
Cho, W.Y.2
Sung, S.A.3
-
32
-
-
0029836444
-
Local administration of antisense phosphorothioate oligonucleotides to the p65 subunit of NF-κB abrogates established experimental colitis in mice
-
Neurath M.F., Pettersson S., Meyer zum Buschenfelde K.H., et al. Local administration of antisense phosphorothioate oligonucleotides to the p65 subunit of NF-κB abrogates established experimental colitis in mice. Nat Med 2 (1996) 998-1004
-
(1996)
Nat Med
, vol.2
, pp. 998-1004
-
-
Neurath, M.F.1
Pettersson, S.2
Meyer zum Buschenfelde, K.H.3
-
33
-
-
4043088499
-
IKKβ links inflammation and tumorigenesis in a mouse model of colitis-associated cancer
-
Greten F.R., Eckmann L., Greten T.F., et al. IKKβ links inflammation and tumorigenesis in a mouse model of colitis-associated cancer. Cell 118 (2004) 285-296
-
(2004)
Cell
, vol.118
, pp. 285-296
-
-
Greten, F.R.1
Eckmann, L.2
Greten, T.F.3
-
34
-
-
42149171210
-
Loss of epithelial RelA results in deregulated intestinal proliferative/apoptotic homeostasis and susceptibility to inflammation
-
Steinbrecher K.A., Harmel-Laws E., Sitcheran R., et al. Loss of epithelial RelA results in deregulated intestinal proliferative/apoptotic homeostasis and susceptibility to inflammation. J Immunol 180 (2008) 2588-2599
-
(2008)
J Immunol
, vol.180
, pp. 2588-2599
-
-
Steinbrecher, K.A.1
Harmel-Laws, E.2
Sitcheran, R.3
-
35
-
-
0034528937
-
Uncoupling Raf1 from MEK1/2 impairs only a subset of cellular responses to Raf activation
-
Pearson G., Bumeister R., Henry D.O., et al. Uncoupling Raf1 from MEK1/2 impairs only a subset of cellular responses to Raf activation. J Biol Chem 275 (2000) 37303-37306
-
(2000)
J Biol Chem
, vol.275
, pp. 37303-37306
-
-
Pearson, G.1
Bumeister, R.2
Henry, D.O.3
-
36
-
-
12944305960
-
Raf induces NF-κB by membrane shuttle kinase MEKK1, a signaling pathway critical for transformation
-
Baumann B., Weber C.K., Troppmair J., et al. Raf induces NF-κB by membrane shuttle kinase MEKK1, a signaling pathway critical for transformation. Proc Natl Acad Sci U S A 97 (2000) 4615-4620
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 4615-4620
-
-
Baumann, B.1
Weber, C.K.2
Troppmair, J.3
-
37
-
-
11844279745
-
Activated macrophages are an adaptive element of the colonic epithelial progenitor niche necessary for regenerative responses to injury
-
Pull S.L., Doherty J.M., Mills J.C., et al. Activated macrophages are an adaptive element of the colonic epithelial progenitor niche necessary for regenerative responses to injury. Proc Natl Acad Sci U S A 102 (2005) 99-104
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 99-104
-
-
Pull, S.L.1
Doherty, J.M.2
Mills, J.C.3
-
38
-
-
0028872649
-
Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation
-
Marshall C.J. Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation. Cell 80 (1995) 179-185
-
(1995)
Cell
, vol.80
, pp. 179-185
-
-
Marshall, C.J.1
-
39
-
-
0036709020
-
Fidelity and spatio-temporal control in MAP kinase (ERKs) signalling
-
Pouyssegur J., Volmat V., and Lenormand P. Fidelity and spatio-temporal control in MAP kinase (ERKs) signalling. Biochem Pharmacol 64 (2002) 755-763
-
(2002)
Biochem Pharmacol
, vol.64
, pp. 755-763
-
-
Pouyssegur, J.1
Volmat, V.2
Lenormand, P.3
-
40
-
-
34047129136
-
Mek1/2 MAPK kinases are essential for mammalian development, homeostasis, and Raf-induced hyperplasia
-
Scholl F.A., Dumesic P.A., Barragan D.I., et al. Mek1/2 MAPK kinases are essential for mammalian development, homeostasis, and Raf-induced hyperplasia. Dev Cell 12 (2007) 615-629
-
(2007)
Dev Cell
, vol.12
, pp. 615-629
-
-
Scholl, F.A.1
Dumesic, P.A.2
Barragan, D.I.3
-
41
-
-
34248591612
-
Targeting the Raf-MEK-ERK mitogen-activated protein kinase cascade for the treatment of cancer
-
Roberts P.J., and Der C.J. Targeting the Raf-MEK-ERK mitogen-activated protein kinase cascade for the treatment of cancer. Oncogene 26 (2007) 3291-3310
-
(2007)
Oncogene
, vol.26
, pp. 3291-3310
-
-
Roberts, P.J.1
Der, C.J.2
-
42
-
-
14644429135
-
Colorectal cancer in patients with inflammatory bowel disease
-
Vagefi P.A., and Longo W.E. Colorectal cancer in patients with inflammatory bowel disease. Clin Colorectal Cancer 4 (2005) 313-319
-
(2005)
Clin Colorectal Cancer
, vol.4
, pp. 313-319
-
-
Vagefi, P.A.1
Longo, W.E.2
|