Glycosaminoglycans and PDGF signaling in mesenchymal cells

Connective Tissue Research

Volumn 49, Issue 3-4, 2008, Pages 153-156

  Zafiropoulos, Alexandros ^a   Fthenou, Eleni ^a   Chatzinikolaou, Georgia ^a   Tzanakakis, George ^a  

^a UNIVERSITY OF CRETE   (Greece)

Author keywords

Chondroitin Sulphate A; Extracellular Matrix; Fibrosarcoma; Glycosaminoglycans; PDGF

Indexed keywords

COLLAGEN; GLYCOSAMINOGLYCAN; HERMES ANTIGEN; HYALURONIC ACID; ISOPROTEIN; PLATELET DERIVED GROWTH FACTOR; PLATELET DERIVED GROWTH FACTOR BB; PLATELET DERIVED GROWTH FACTOR BETA RECEPTOR;

CARBOHYDRATE ANALYSIS; CELL DIFFERENTIATION; CELL GROWTH; CELL INVASION; CELL MIGRATION; CELL PROLIFERATION; CHEMOTAXIS; COLLAGEN SYNTHESIS; EXTRACELLULAR MATRIX; HUMAN; MESENCHYME CELL; PROTEIN BINDING; PROTEIN CARBOHYDRATE INTERACTION; PROTEIN DETERMINATION; PROTEIN PHOSPHORYLATION; REGULATORY MECHANISM; REVIEW; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; TRANSLATION REGULATION;

ANIMALS; ANTIGENS, CD44; CELL MOVEMENT; CELL PROLIFERATION; GLYCOSAMINOGLYCANS; HUMANS; MESODERM; MODELS, BIOLOGICAL; MYOCYTES, SMOOTH MUSCLE; PHOSPHORYLATION; PLATELET-DERIVED GROWTH FACTOR; RECEPTORS, PLATELET-DERIVED GROWTH FACTOR; SIGNAL TRANSDUCTION;

EID: 48549084341     PISSN: 03008207     EISSN: 16078438     Source Type: Journal    
DOI: 10.1080/03008200802148702     Document Type: Review

References (30)

1. Kelly, J. D., Raines, E. W., Ross, R. and Murray, M. J. (1985) The B chain of PDGF alone is sufficient for mitogenesis. 4, pp. 3399-3405.
2. Heldin, C. H. (1992) Structural and functional studies on platelet-derived growth factor. 11, pp. 4251-4259.
3. Li, X. and Eriksson, U. (2003) Novel PDGF family members: PDGF-C and PDGF-D. 14, pp. 91-98.
4. Pollock, R. A. and Richardson, W. D. (1992) The alternative-splice isoforms of the PDGF A-chain differ in their ability to associate with the extracellular matrix and to bind heparin in vitro. 7, pp. 267-277.
5. Andersson, M., Ostman, A., Westermark, B. and Heldin, C. H. (1994) Characterization of the retention motif in the C-terminal part of the long splice form of platelet-derived growth factor A-chain. 269, pp. 926-930.
6. Tallquist, M. and Kazlauskas, A. (2004) PDGF signaling in cells and mice. 15, pp. 205-213.
7. Board, R. and Jayson, G. C. (2005) Platelet-derived growth factor receptor (PDGFR): A target for anticancer therapeutics. 8, pp. 75-83.
8. Ostman, A. (2004) PDGF receptors-mediators of autocrine tumor growth and regulators of tumor vasculature and stroma. 15, pp. 275-286.
9. Shimizu, A., O'Brien, K. P., Sjoblom, T., Pietras, K., Buchdunger, E., Collins, V. P., Heldin, C. H., Dumanski, J. P. and Ostman, A. (1999) The dermatofibrosarcoma protuberans-associated collagen type Ialpha1/ platelet-derived growth factor (PDGF) B-chain fusion gene generates a transforming protein that is processed to functional PDGF-BB. 59, pp. 3719-3723.
10. Kikuchi, K., Soma, Y., Fujimoto, M., Kadono, T., Sato, S., Abe, M., Ohhara, K. and Takehara, K. (1993) Dermatofibrosarcoma protuberans: increased growth response to platelet-derived growth factor BB in cell culture. 196, pp. 409-415.
11. Pietras, K., Sjoblom, T., Rubin, K., Heldin, C. H. and Ostman, A. (2003) PDGF receptors as cancer drug targets. 3, pp. 439-443.
12. O'Brien, K. P., Seroussi, E., Dal Cin, P., Sciot, R., Mandahl, N., Fletcher, J. A., Turc-Carel, C. and Dumanski, J. P. (1998) Various regions within the alpha-helical domain of the COL1A1 gene are fused to the second exon of the PDGFB gene in dermatofibrosarcomas and giant-cell fibroblastomas. 23, pp. 187-193.
13. Simon, M. P., Pedeutour, F., Sirvent, N., Grosgeorge, J., Minoletti, F., Coindre, J. M., Terrier-Lacombe, M. J., Mandahl, N., Craver, R. D., Blin, N., Sozzi, G., Turc-Carel, C., O'Brien, K. P., Kedra, D., Fransson, I., Guilbaud, C. and Dumanski, J. P. (1997) Deregulation of the platelet-derived growth factor B-chain gene via fusion with collagen gene COL1A1 in dermatofibrosarcoma protuberans and giant-cell fibroblastoma. Deregulation of the platelet-derived growth factor B-chain gene via fusion with collagen gene COL1A1 in dermatofibrosarcoma protuberans and giant-cell fibroblastoma. 15, pp. 95-98.
14. Badache, A. and De Vries, G. H. (1998) Neurofibrosarcoma-derived Schwann cells overexpress platelet-derived growth factor (PDGF) receptors and are induced to proliferate by PDGF BB. 177, pp. 334-342.
15. Rapraeger, A., Krufka, A. and Olwin, B. B. (1991) Requirement of heparan sulfate for bFGF-mediated fibroblast growth and myoblast differentiation. 252, pp. 1705-1708.
16. Fager, G., Camejo, G., Olsson, U., Ostergren-Lunden, G., Lustig, F. and Bondjers, G. (1995) Binding of platelet-derived growth factor and low density lipoproteins to glycosaminoglycan species produced by human arterial smooth muscle cells. 163, pp. 380-392.
17. Lustig, F., Hoebeke, J., Simonson, C., Ostergren-Lunden, G., Bondjers, G., Ruetchi, U. and Fager, G. (1999) Processing of PDGF gene products determines interactions with glycosaminoglycans. 12, pp. 112-120.
18. Garcia-Olivas, R., Hoebeke, J., Castel, S., Reina, M., Fager, G., Lustig, F. and Vilaro, S. (2003) Differential binding of platelet-derived growth factor isoforms to glycosaminoglycans. 120, 371-382.
19. Lustig, F., Hoebeke, J., Ostergren-Lunden, G., Velge-Roussel, F., Bondjers, G., Olsson, U., Ruetschi, U. and Fager, G. (1996) Alternative splicing determines the binding of platelet-derived growth factor (PDGF-AA) to glycosaminoglycans. 35, pp. 12077-12085.
20. Lugemwa, F. N. and Esko, J. D. (1991) Estradiol beta-D-xyloside, an efficient primer for heparan sulfate biosynthesis. 266, pp. 6674-6677.
21. Fthenou, E., Zafiropoulos, A., Tsatsakis, A., Stathopoulos, A., Karamanos, N. K. and Tzanakakis, G. N. (2006) Chondroitin sulfate A chains enhance platelet derived growth factor-mediated signalling in fibrosarcoma cells. 38, pp. 2141-2150.
22. Nikitovic, D., Zafiropoulos, A., Tzanakakis, G. N., Karamanos, N. K. and Tsatsakis, A. M. (2005) Effects of glycosaminoglycans on cell proliferation of normal osteoblasts and human osteosarcoma cells depend on their type and fine chemical compositions. 25, pp. 2851-2856.
23. Schneller, M., Vuori, K. and Ruoslahti, E. (1997) Alphavbeta3 integrin associates with activated insulin and PDGFbeta receptors and potentiates the biological activity of PDGF. 16, pp. 5600-5607.
24. Woodard, A. S., Garcia-Cardena, G., Leong, M., Madri, J. A., Sessa, W. C. and Languino, L. R. (1998) The synergistic activity of alphavbeta3 integrin and PDGF receptor increases cell migration. 111, pp. 469-478.
25. Ronnstrand, L. and Heldin, C. H. (2001) Mechanisms of platelet-derived growth factor-induced chemotaxis. 91, pp. 757-762.
26. Selbi, W., de la Motte, C. A., Hascall, V. C., Day, A. J., Bowen, T. and Phillips, A. O. (2006) Characterization of hyaluronan cable structure and function in renal proximal tubular epithelial cells. 70, pp. 1287-1295.
27. Nili, N., Cheema, A. N., Giordano, F. J., Barolet, A. W., Babaei, S., Hickey, R., Eskandarian, M. R., Smeets, M., Butany, J., Pasterkamp, G. and Strauss, B. H. (2003) Decorin inhibition of PDGF-stimulated vascular smooth muscle cell function: Potential mechanism for inhibition of intimal hyperplasia after balloon angioplasty. 163, pp. 869-878.
28. Li, L., Heldin, C. H. and Heldin, P. (2006) Inhibition of platelet-derived growth factor-BB-induced receptor activation and fibroblast migration by hyaluronan activation of CD44. 281, pp. 26512-26519.
29. Lesley, J., Hascall, V. C., Tammi, M. and Hyman, R. (2000) Hyaluronan binding by cell surface CD44. 275, pp. 26967-26975.
30. de La Motte, C. A., Hascall, V. C., Calabro, A., Yen-Lieberman, B. and Strong, S. A. (1999) Mononuclear leukocytes preferentially bind via CD44 to hyaluronan on human intestinal mucosal smooth muscle cells after virus infection or treatment with poly(I.C).274, pp. 30747-30755.