Persistence in alterations in the ontogeny of cerebral and hepatic cytochrome P450s following prenatal exposure to low doses of lindane

Toxicological Sciences

Volumn 101, Issue 2, 2008, Pages 331-340

  Johri, Ashu ^a   Dhawan, Alok ^a   Singh, Ram Lakhan ^b   Parmar, Devendra ^a  

^a CSIR INDIAN INSTITUTE OF TOXICOLOGY RESEARCH   (India)

^b DR RAM MANOHAR LOHIA AVADH UNIVERSITY   (India)

Author keywords

hexachlorocyclohexane (lindane); Cytochrome P450; Expression; Gestation; Rat

Indexed keywords

CYTOCHROME P450; CYTOCHROME P450 1A1; CYTOCHROME P450 1A2; CYTOCHROME P450 2B1; CYTOCHROME P450 2B2; CYTOCHROME P450 2E1; ENVIRONMENTAL CHEMICAL; LINDANE; MESSENGER RNA;

ADULTHOOD; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN TOXICITY; BREAST MILK; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME DEGRADATION; FEMALE; FETUS; GENE EXPRESSION; LIVER TOXICITY; MALE; NERVE CELL DIFFERENTIATION; NEUROTOXICITY; NONHUMAN; PERINATAL PERIOD; PLACENTAL TRANSFER; POSTNATAL DEVELOPMENT; PRENATAL EXPOSURE; PROGENY; RAT; XENOBIOTIC METABOLISM;

AGING; ANIMALS; CEREBRAL CORTEX; CYTOCHROME P-450 ENZYME SYSTEM; DOSE-RESPONSE RELATIONSHIP, DRUG; ENVIRONMENTAL POLLUTANTS; ENZYME INDUCTION; FEMALE; GESTATIONAL AGE; ISOENZYMES; LINDANE; LIVER; MALE; MICROSOMES; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; RATS; RATS, WISTAR; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

RATTUS;

EID: 38149014753     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfm269     Document Type: Article

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