메뉴 건너뛰기




Volumn 38, Issue 6, 2008, Pages 313-319

The protective effect of simvastatin on monocrotaline-induced pulmonary hypertension in rats

Author keywords

Pulmonary circulation; Pulmonary hypertension; Statins

Indexed keywords

AQUAPORIN 1; AQUAPORIN 2; MONOCROTALINE; SIMVASTATIN;

EID: 48349129130     PISSN: 17385520     EISSN: 17385555     Source Type: Journal    
DOI: 10.4070/kcj.2008.38.6.313     Document Type: Article
Times cited : (4)

References (28)
  • 1
    • 2942541475 scopus 로고    scopus 로고
    • Cellular and molecular pathobiology of pulmonary arterial hypertension
    • Humbert M, Morrell NW, Archer SL, et al. Cellular and molecular pathobiology of pulmonary arterial hypertension. J Am Coll Cardiol 2004; 43 (Suppl): 13S-24S.
    • (2004) J Am Coll Cardiol , vol.43 , Issue.SUPPL.
    • Humbert, M.1    Morrell, N.W.2    Archer, S.L.3
  • 2
    • 33645104291 scopus 로고    scopus 로고
    • Pulmonary arterial hypertension: New insights and new hope
    • Martin KB, Klinger JR, Rounds SI. Pulmonary arterial hypertension: new insights and new hope. Respirology 2006; 11: 6-17.
    • (2006) Respirology , vol.11 , pp. 6-17
    • Martin, K.B.1    Klinger, J.R.2    Rounds, S.I.3
  • 3
    • 24144484100 scopus 로고    scopus 로고
    • Current treatment strategies for pulmonary arterial hypertension
    • Lee SH, Rubin LJ. Current treatment strategies for pulmonary arterial hypertension. J Intern Med 2005; 258: 199-215.
    • (2005) J Intern Med , vol.258 , pp. 199-215
    • Lee, S.H.1    Rubin, L.J.2
  • 4
    • 0033160557 scopus 로고    scopus 로고
    • Prognoses of primary pulmonary hypertension and chronic major vessel thromboembolic pulmonary hypertension determined from cumulative survival curves
    • Kunieda T, Nakanishi N, Satoh T, Kyotani S, Okano Y, Nagaya N. Prognoses of primary pulmonary hypertension and chronic major vessel thromboembolic pulmonary hypertension determined from cumulative survival curves. Intern Med 1999; 38: 543-6.
    • (1999) Intern Med , vol.38 , pp. 543-546
    • Kunieda, T.1    Nakanishi, N.2    Satoh, T.3    Kyotani, S.4    Okano, Y.5    Nagaya, N.6
  • 6
    • 19044366349 scopus 로고    scopus 로고
    • Simvastatin treatment of pulmonary hypertension an observational case series
    • Kao PN. Simvastatin treatment of pulmonary hypertension an observational case series. Chest 2005; 127: 1446-52.
    • (2005) Chest , vol.127 , pp. 1446-1452
    • Kao, P.N.1
  • 7
    • 28144440031 scopus 로고    scopus 로고
    • Simvastatin enhances bone mor phogenetic protein receptor type II expression
    • Hu H, Sung A, Zhao G, et al. Simvastatin enhances bone mor phogenetic protein receptor type II expression. Biochem Biophys Res Commun 2006; 339: 59-64.
    • (2006) Biochem Biophys Res Commun , vol.339 , pp. 59-64
    • Hu, H.1    Sung, A.2    Zhao, G.3
  • 8
    • 0041859249 scopus 로고    scopus 로고
    • Attenuation of chronic hypoxic pulmonary hypertension by simvastatin
    • Girgis RE, Li D, Zhan X, et al. Attenuation of chronic hypoxic pulmonary hypertension by simvastatin. Am J Physiol Heart Circ Physiol 2003; 285: H938-45.
    • (2003) Am J Physiol Heart Circ Physiol , vol.285
    • Girgis, R.E.1    Li, D.2    Zhan, X.3
  • 9
    • 0141730236 scopus 로고    scopus 로고
    • Simvastatin rescues rats from fatal pulmonary hypertension by inducing apoptosis of neointimal smooth muscle cells
    • Nishimura T, Vaszar LT, Faul JL, et al. Simvastatin rescues rats from fatal pulmonary hypertension by inducing apoptosis of neointimal smooth muscle cells. Circulation 2003; 108: 1640-5.
    • (2003) Circulation , vol.108 , pp. 1640-1645
    • Nishimura, T.1    Vaszar, L.T.2    Faul, J.L.3
  • 11
    • 0030013048 scopus 로고    scopus 로고
    • Aquaporin-1 water channel protein in lung: Ontogeny, steroid-induced expression, and distribution in rat
    • King LS, Nielsen S, Agre P. Aquaporin-1 water channel protein in lung: ontogeny, steroid-induced expression, and distribution in rat. J Clin Invest 1996; 97: 2183-91.
    • (1996) J Clin Invest , vol.97 , pp. 2183-2191
    • King, L.S.1    Nielsen, S.2    Agre, P.3
  • 12
    • 0036781506 scopus 로고    scopus 로고
    • Aquaporins and disease: Lessons from mice to humans
    • King LS, Yasui M. Aquaporins and disease: lessons from mice to humans. Trends Endocrinol Metab 2002; 13: 355-60.
    • (2002) Trends Endocrinol Metab , vol.13 , pp. 355-360
    • King, L.S.1    Yasui, M.2
  • 13
    • 0030922702 scopus 로고    scopus 로고
    • Congestive heart failure in rats is associated with increased expression and targeting of aquaporin-2 water channel in collecting duct
    • Nielsen S, Terris J, Andersen D, et al. Congestive heart failure in rats is associated with increased expression and targeting of aquaporin-2 water channel in collecting duct. Proc Natl Acad Sci U S A 1997; 94: 5450-5.
    • (1997) Proc Natl Acad Sci U S A , vol.94 , pp. 5450-5455
    • Nielsen, S.1    Terris, J.2    Andersen, D.3
  • 14
    • 0025608842 scopus 로고
    • Development of morphologic, hemodynamic, and biochemical changes in lungs of rats given monocrotaline pyrrole
    • Reindel JF, Ganey PE, Wagner JG, Slocombe RF, Roth RA. Development of morphologic, hemodynamic, and biochemical changes in lungs of rats given monocrotaline pyrrole. Toxicol Appl Pharmacol 1990; 106: 179-200.
    • (1990) Toxicol Appl Pharmacol , vol.106 , pp. 179-200
    • Reindel, J.F.1    Ganey, P.E.2    Wagner, J.G.3    Slocombe, R.F.4    Roth, R.A.5
  • 15
    • 0025837793 scopus 로고
    • Survival in patients with primary pulmonary hypertension: Results from a national prospective registry
    • D'Alonzo GE, Barst RJ, Ayres SM, et al. Survival in patients with primary pulmonary hypertension: results from a national prospective registry. Ann Intern Med 1991; 115: 343-9.
    • (1991) Ann Intern Med , vol.115 , pp. 343-349
    • D'Alonzo, G.E.1    Barst, R.J.2    Ayres, S.M.3
  • 16
    • 33845364931 scopus 로고    scopus 로고
    • A clinical review of primary pulmonary hypertension
    • Lee WD, Kim DS, Lee JH, et al. A clinical review of primary pulmonary hypertension. Korean Circ J 2003; 33: 507-12.
    • (2003) Korean Circ J , vol.33 , pp. 507-512
    • Lee, W.D.1    Kim, D.S.2    Lee, J.H.3
  • 17
    • 34447318895 scopus 로고    scopus 로고
    • Clinical characteristics and prognostic factors of patients with severe pulmonary hypertension
    • Lee WS, Kim KH, Jeong DH, et al. Clinical characteristics and prognostic factors of patients with severe pulmonary hypertension. Korean Circ J 2007; 37: 265-70.
    • (2007) Korean Circ J , vol.37 , pp. 265-270
    • Lee, W.S.1    Kim, K.H.2    Jeong, D.H.3
  • 18
    • 10744233302 scopus 로고    scopus 로고
    • Chronic sildenafil treatment inhibits monocrotaline-induced pulmonary hypertension in rats
    • Schermuly RT, Kreisselmeier KP, Ghofrani HA, et al. Chronic sildenafil treatment inhibits monocrotaline-induced pulmonary hypertension in rats. Am J Respir Crit Care Med 2004; 169: 39-45.
    • (2004) Am J Respir Crit Care Med , vol.169 , pp. 39-45
    • Schermuly, R.T.1    Kreisselmeier, K.P.2    Ghofrani, H.A.3
  • 19
    • 3042511852 scopus 로고    scopus 로고
    • Pulmonary arterial hypertension: Future directions: report of a National Heart, Lung and Blood Institute/Office of Rare Diseases workhop
    • Newman JH, Fanburg BL, Archer SL, et al. Pulmonary arterial hypertension: future directions: report of a National Heart, Lung and Blood Institute/Office of Rare Diseases workhop. Circulation 2004; 109: 2947-52.
    • (2004) Circulation , vol.109 , pp. 2947-2952
    • Newman, J.H.1    Fanburg, B.L.2    Archer, S.L.3
  • 20
    • 0035572718 scopus 로고    scopus 로고
    • Pleiotropic effects of 3-hydroxy-3-methyl- glutaryl coenzyme a reductase inhibitors
    • Takemoto M, Liao JK. Pleiotropic effects of 3-hydroxy-3-methyl- glutaryl coenzyme a reductase inhibitors. Arterioscler Thromb Vasc Biol 2001; 21: 1712-9.
    • (2001) Arterioscler Thromb Vasc Biol , vol.21 , pp. 1712-1719
    • Takemoto, M.1    Liao, J.K.2
  • 21
    • 0031451344 scopus 로고    scopus 로고
    • Inhibition of 3-hydroxy-3-methyl-glutaryl (HMG)-CoA reductase blocks hypoxia-mediated down-regulation of endothelial nitric oxide synthase
    • Laufs U, Fata VL, Liao JK. Inhibition of 3-hydroxy-3-methyl-glutaryl (HMG)-CoA reductase blocks hypoxia-mediated down-regulation of endothelial nitric oxide synthase. J Biol Chem 1997; 272: 31725-9.
    • (1997) J Biol Chem , vol.272 , pp. 31725-31729
    • Laufs, U.1    Fata, V.L.2    Liao, J.K.3
  • 22
    • 33748778726 scopus 로고    scopus 로고
    • Effects of simvastatin alone or combined with ramipril on nitric oxide bioactivity and inflammation markers in hypercholesterolemic patients
    • Son JW, Koh KK, You SM, et al. Effects of simvastatin alone or combined with ramipril on nitric oxide bioactivity and inflammation markers in hypercholesterolemic patients. Korean Circ J 2003; 33: 1053-9
    • (2003) Korean Circ J , vol.33 , pp. 1053-1059
    • Son, J.W.1    Koh, K.K.2    You, S.M.3
  • 24
    • 0035160217 scopus 로고    scopus 로고
    • Aquaporin channels may modulate ventilator-induced lung injury
    • Hales CA, Du HK, Volokhov A, Mourfarrej R, Quinn DA. Aquaporin channels may modulate ventilator-induced lung injury. Respir Physiol 2001; 124: 159-66.
    • (2001) Respir Physiol , vol.124 , pp. 159-166
    • Hales1    CA, D.H.2    Volokhov, A.3    Mourfarrej, R.4    Quinn, D.A.5
  • 25
    • 4444293085 scopus 로고    scopus 로고
    • The role of aquaporin-1 (AQP1) expression in a murine model of lipopolysaccharide-induced acute lung injury
    • Su X, Song Y, Jiang J, Bai C. The role of aquaporin-1 (AQP1) expression in a murine model of lipopolysaccharide-induced acute lung injury. Respir Physiol Neurobiol 2004; 142: 1-11.
    • (2004) Respir Physiol Neurobiol , vol.142 , pp. 1-11
    • Su, X.1    Song, Y.2    Jiang, J.3    Bai, C.4
  • 26
    • 0036661083 scopus 로고    scopus 로고
    • Aquaporin water channels-from atomic structure to clinical medicine
    • Agre P, King LS, Yasui M, et al. Aquaporin water channels-from atomic structure to clinical medicine. J Physiol 2002; 542: 3-16.
    • (2002) J Physiol , vol.542 , pp. 3-16
    • Agre, P.1    King, L.S.2    Yasui, M.3
  • 27
    • 0036081001 scopus 로고    scopus 로고
    • Losartan treatment normalizes renal sodium and water handling in rats with mild congestive heart failure
    • Staahltoft D, Nielsen S, Janjua NR, et al. Losartan treatment normalizes renal sodium and water handling in rats with mild congestive heart failure. Am J Physiol Renal Physiol 2002; 282: F307-15.
    • (2002) Am J Physiol Renal Physiol , vol.282
    • Staahltoft, D.1    Nielsen, S.2    Janjua, N.R.3
  • 28
    • 1542358797 scopus 로고    scopus 로고
    • Normalization of renal aquaporin-2 water channel expression by fosinopril, valsartan, and combination therapy in congestive heart failure: A new mechanism of action
    • Yu CM, Wing-Hon Lai K, Li PS, Lam KY, Leung JC, Lai KN. Normalization of renal aquaporin-2 water channel expression by fosinopril, valsartan, and combination therapy in congestive heart failure: a new mechanism of action. J Mol Cell Cardiol 2004; 36: 445-53.
    • (2004) J Mol Cell Cardiol , vol.36 , pp. 445-453
    • Yu, C.M.1    Wing-Hon Lai, K.2    Li, P.S.3    Lam, K.Y.4    Leung, J.C.5    Lai, K.N.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.