The extracolonic cancer spectrum in females with the common 'South African' hMLH1 c.C1528T mutation

Familial Cancer

Volumn 7, Issue 3, 2008, Pages 191-198

  Blokhuis, Maria M ^a,b   Goldberg, Paul A ^c   Pietersen, G Elize ^a   Algar, Ursula ^c   Vorster, A Alvera ^a   Govender, Dhiren ^a   Ramesar, Raj S ^a  

^a UNIVERSITY OF CAPE TOWN   (South Africa)

^b VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^c UNIVERSITY OF CAPE TOWN   (South Africa)

Author keywords

Breast cancer; Colon cancer; Extracolonic cancer; hMLH1; HNPCC

Indexed keywords

GENE PRODUCT;

ADULT; ALLELE; ARTICLE; BREAST CANCER; CANCER INCIDENCE; COLORECTAL CANCER; DISEASE PREDISPOSITION; ENDOMETRIUM CANCER; FAMILIAL CANCER; FEMALE; GENE EXPRESSION; GENE MUTATION; HUMAN; IMMUNOHISTOCHEMISTRY; KIDNEY CARCINOMA; MAJOR CLINICAL STUDY; MICROSATELLITE INSTABILITY; OVARY CANCER; PHENOTYPE; PRIMARY TUMOR; PRIORITY JOURNAL; STATISTICAL SIGNIFICANCE; WILD TYPE;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ADULT; ALLELES; CASE-CONTROL STUDIES; COHORT STUDIES; COLORECTAL NEOPLASMS, HEREDITARY NONPOLYPOSIS; CYSTEINE; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HUMANS; INCIDENCE; MICROSATELLITE INSTABILITY; MIDDLE AGED; MUTATION; NEOPLASMS; NEOPLASMS, MULTIPLE PRIMARY; NUCLEAR PROTEINS; PHENOTYPE; POPULATION SURVEILLANCE; RISK FACTORS; SEX FACTORS; SIBLINGS; SOUTH AFRICA; THREONINE;

EID: 48349126284     PISSN: 13899600     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10689-007-9174-4     Document Type: Article

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