Genetic basis of familial endometrial cancer: Is there more to learn?

Journal of Clinical Oncology

Volumn 23, Issue 21, 2005, Pages 4570-4573

  Boyd, Jeff ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN MLH1; PROTEIN MSH2; PROTEIN MSH6; CARRIER PROTEIN; DNA BINDING PROTEIN; G T MISMATCH BINDING PROTEIN; G-T MISMATCH-BINDING PROTEIN; MLH1 PROTEIN, HUMAN; MSH2 PROTEIN, HUMAN; NUCLEAR PROTEIN; ONCOPROTEIN; TUMOR PROTEIN;

CANCER RISK; COLORECTAL CANCER; EDITORIAL; ENDOMETRIUM CANCER; FAMILIAL CANCER; GENE MUTATION; GENETIC ANALYSIS; HUMAN; MICROSATELLITE INSTABILITY; PRIORITY JOURNAL; COLORECTAL TUMOR; ENDOMETRIUM TUMOR; FEMALE; GENETICS; NOTE; NUCLEOTIDE SEQUENCE;

CARRIER PROTEINS; COLORECTAL NEOPLASMS, HEREDITARY NONPOLYPOSIS; DNA MUTATIONAL ANALYSIS; DNA-BINDING PROTEINS; ENDOMETRIAL NEOPLASMS; FEMALE; HUMANS; MUTS HOMOLOG 2 PROTEIN; NEOPLASM PROTEINS; NUCLEAR PROTEINS; PROTO-ONCOGENE PROTEINS;

EID: 23044467616     PISSN: 0732183X     EISSN: None     Source Type: Journal    
DOI: 10.1200/JCO.2005.01.902     Document Type: Editorial

References (34)

1. Brøbeck O: Heredity in carcinoma uteri [doctoral thesis]. University of Copenhagen, Copenhagen, Denmark, 1949
2. Purdie AW: Carcinoma corporis uteri in 2 sisters aged 34 and 32 years. J Obstet Gynaecol Br Emp 52:575-579, 1945
3. Porter JE: Cancer of corpus uteri in premenopausal siblings. Obstet Gynecoi 28:675-679, 1966
4. Bergsjo P, Kolstad P: The ABO blood groups and cancer of the female genital tract. Acta Obstet Gynecol Scand 41:397-404, 1962
5. Schildkraut JM, Risch N, Thompson WD: Evaluating genetic association among ovarian, breast, and endometrial cancer: Evidence for a breast/ovarian cancer relationship. Am J Hum Genet 45:521-529, 1989
6. Gruber SB, Thompson WD: A population-based study of endometrial cancer and familial risk in younger women. Cancer Epidemiol Biomarkers Prev 5:411-417, 1996
7. Warthin AS: Heredity with reference to carcinoma as shown by the study of the cases examined in the pathological laboratory of the University of Michigan, 1895-1913. Arch Intern Med 12:546-555, 1913
8. Hauser IJ, Weller CV: A further report on the cancer family of Warthin. Am J Cancer 27:434-444, 1936
9. Lynch HT, Krush AJ: Cancer family G revisited: 1895-1970. Cancer 27:1505-1511, 1971
10. Lynch HT, Shaw MW, Magnuson CW, et al: Hereditary factors in cancer: Study of two large midwestern kindreds. Arch Intern Med 117:206-212, 1966
11. Boland CR, Troncale FJ: Familial colonic cancer without antecedent polyposis. Ann Intern Med 100:700-701, 1984
12. Peltomäki P: Role of DNA mismatch repair defects in the pathogenesis of human cancer. J Clin Oncol 21:1174-1179, 2003
13. Lynch HT, de la Chapelle A: Hereditary colorectal cancer. N Engl J Med 348:919-932, 2003
14. Lynch HT, Lynch JF: Lynch syndrome: History and current status. Dis Markers 20:181-198, 2004
15. Steichen-Gersdorf E, Gallion HH, Ford D, et al: Familial site-specific ovarian cancer is linked to BRCA1 on 17q12-21. Am J Hum Genet 55:870-875, 1994
16. Easton DF: How many more breast cancer predisposition genes are there? Breast Cancer Res 1:14-17, 1999
17. Peto J: Breast cancer susceptibility: A new look at an old model. Cancer Cell 1:411-412, 2002
18. Vasen HF, Wijnen JT, Menko FH, et al: Cancer risk in families with hereditary nonpolyposis colorectal cancer diagnosed by mutation analysis. Gastroenterology 110:1020-1027, 1996
19. Dunlop MG, Farrington SM, Carothers AD, et al: Cancer risk associated with germline DNA mismatch repair gene mutations. Hum Mol Genet 6:105-110, 1997
20. Aarnio M, Sankila R, Pukkala E, et al: Cancer risk in mutation carriers of DNA-mismatch-repair genes. Int J Cancer 81:214-218, 1999
21. Vasen HF, Watson P, Mecklin JP, et al: New clinical criteria for hereditary nonpolyposis colorectal cancer (HNPCC, Lynch syndrome) proposed by the International Collaborative Group on HNPCC. Gastroenterology 116:1453-1456, 1999
22. Lynch HT, Krush AJ, Larsen AL, et al: Endometrial carcinoma: Multiple primary malignancies, constitutional factors, and heredity. Am J Med Sci 36:381-390, 1966
23. Boltenberg A, Furgyik S, Kullander S: Familial cancer aggregation in cases of adenocarcinoma corporis uteri. Acta Obstet Gynecol Scand 69:249-258, 1990
24. Sandles LG, Shulman LP, Elias S, et al: Endometrial adenocarcinoma: Genetic analysis suggesting heritable site-specific uterine cancer. Gynecol Oncol 47:167-171, 1992
25. Lynch HT, Lynch J, Conway T, et al: Familial aggregation of carcinoma of the endometrium Am J Obstet Gynecol 171:24-27, 1994
26. Wijnen J, de Leeuw W, Vasen H, et al: Familial endometrial cancer in female carriers of MSH6 germline mutations. Nat Genet 23:142-144, 1999
27. Oliikainen M, Abdel-Rahman WM, Moisio A-L, et al: Molecular analysis of familial endometrial carcinoma: A manifestation of hereditary nonpolyposis colorectal cancer or a separate syndrome? J Clin Oncol 23:4609-4616, 2005
28. Umar A, Boland CR, Terdiman JP, et al: Revised Bethesda Guidelines for hereditary nonpolyposis colorectal cancer (Lynch syndrome) and microsatellite instability. J Natl Cancer Inst 96:261-268, 2004
29. Boland CR, Thibodeau SN, Hamilton SR, et al: A National Cancer Institute Workshop on Microsatellite Instability for Cancer Detection and Familial Predisposition: Development of international criteria for the determination of microsatellite instability in colorectal cancer. Cancer Res 58: 5248-5257, 1998
30. De Vivo I, Huggins GS, Hankinson SE, et al: A functional polymorphism in the promoter of the progesterone receptor gene associated with endometrial cancer risk. Proc Natl Acad Sci U S A 99:12263-12268, 2002
31. Sasaki M, Tanaka Y, Kaneuchi M, et al: CYP1B1 gene polymorphisms have higher risk for endometrial cancer, and positive correlations with estrogen receptor alpha and estrogen receptor beta expressions. Cancer Res 63:3913-3918, 2003
32. Berstein LM, Imyanitov EN, Kovalevskij AJ, et al: CYP17 and CYP19 genetic polymorphisms in endometrial cancer: Association with intratumoral aromatase activity. Cancer Lett 207:191-196, 2004
33. Houlston RS, Peto J: The search for low-penetrance cancer susceptibility alleles. Oncogene 23:6471-6476, 2004
34. de la Chapelle A: Genetic predisposition to colorectal cancer. Nat Rev Cancer 4:769-780, 2004