Lipopolysaccharide up-regulates IL-6Rα expression in cultured leptomeningeal cells via activation of ERK1/2 pathway

Neurochemical Research

Volumn 33, Issue 9, 2008, Pages 1901-1910

  Wang, Ting ^a   Wang, Bai Ren ^a   Zhao, Hua Zhou ^b   Kuang, Fang ^a   Fan, Juan ^a   Duan, Xiao Li ^a   Ju, Gong ^a  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^b FOURTH MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Interleukin 6 receptors; Leptomeningeal cell; LPS; MAPK pathways; Phospho ERK1 2

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; GLYCOPROTEIN GP 130; INTERLEUKIN 6 RECEPTOR ALPHA; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3;

ANIMAL CELL; ARTICLE; ASTROCYTE; CELL CULTURE; CONTROLLED STUDY; CULTURE MEDIUM; CYTOKINE RELEASE; DOSE TIME EFFECT RELATION; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; IMMUNOCYTOCHEMISTRY; IMMUNOSTIMULATION; LEPTOMENINX; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION;

ANIMALS; ANIMALS, NEWBORN; CELLS, CULTURED; CYTOKINE RECEPTOR GP130; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; ENZYME INHIBITORS; FLAVONOIDS; LIPOPOLYSACCHARIDES; MAP KINASE SIGNALING SYSTEM; MENINGES; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; PHOSPHORYLATION; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, INTERLEUKIN-6;

EID: 48349097581     PISSN: 03643190     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11064-008-9667-z     Document Type: Article

References (53)

1. H Super A Martinez E Soriano 1997 Degeneration of Cajal-Retzius cells in the developing cerebral cortex of the mouse after ablation of meningeal cells by 6-hydroxydopamine Brain Res Dev Brain Res 98 15 20
2. D Hartmann MW Ziegenhagen J Sievers 1998 Meningeal cells stimulate neuronal migration and the formation of radial glial fascicles from the cerebellar external granular layer Neurosci Lett 244 129 132
3. V Borrell O Marin 2006 Meninges control tangential migration of hem-derived Cajal-Retzius cells via CXCL12/CXCR4 signaling Nat Neurosci 9 1284 1293
4. S Tamura Y Morikawa E Senba 2003 Localization of oncostatin M receptor beta in adult and developing CNS Neuroscience 119 991 997
5. K Ishikawa K Kabeya M Shinoda 1995 Meninges play a neurotrophic role in the regeneration of vasopressin nerves after hypophysectomy Brain Res 677 20 28
6. K Reiss R Mentlein J Sievers 2002 Stromal cell-derived factor 1 is secreted by meningeal cells and acts as chemotactic factor on neuronal stem cells of the cerebellar external granular layer Neuroscience 115 295 305
7. AY Shih H Erb X Sun 2006 Cystine/glutamate exchange modulates glutathione supply for neuroprotection from oxidative stress and cell proliferation J Neurosci 26 10514 10523
8. VH Perry 2004 The influence of systemic inflammation on inflammation in the brain: implications for chronic neurodegenerative disease Brain Behav Immun 18 407 413
9. BV Garabedian Y Lemaigre-Dubreuil J Mariani 2000 Central origin of IL-1beta produced during peripheral inflammation: role of meninges Brain Res Mol Brain Res 75 259 263
10. Y Xia TL Krukoff 2003 Differential neuronal activation in the hypothalamic paraventricular nucleus and autonomic/neuroendocrine responses to I.C.V. endotoxin Neuroscience 121 219 231
11. Z Wu J Zhang H Nakanishi 2005 Leptomeningeal cells activate microglia and astrocytes to induce IL-10 production by releasing pro-inflammatory cytokines during systemic inflammation J Neuroimmunol 167 90 98
12. M Christodoulides BL Makepeace KA Partridge 2002 Interaction of Neisseria meningitidis with human meningeal cells induces the secretion of a distinct group of chemotactic, proinflammatory, and growth-factor cytokines Infect Immun 70 4035 4044
13. JP Konsman S Vigues L Mackerlova 2004 Rat brain vascular distribution of interleukin-1 type-1 receptor immunoreactivity: relationship to patterns of inducible cyclooxygenase expression by peripheral inflammatory stimuli J Comp Neurol 472 113 129
14. JC Schiltz PE Sawchenko 2002 Distinct brain vascular cell types manifest inducible cyclooxygenase expression as a function of the strength and nature of immune insults J Neurosci 22 5606 5618
15. N Quan M Whiteside L Kim 1997 Induction of inhibitory factor kappaBalpha mRNA in the central nervous system after peripheral lipopolysaccharide administration: an in situ hybridization histochemistry study in the rat Proc Natl Acad Sci USA 94 10985 10990
16. M Hartlage-Rubsamen R Lemke R Schliebs 1999 Interleukin-1beta, inducible nitric oxide synthase, and nuclear factor-kappaB are induced in morphologically distinct microglia after rat hippocampal lipopolysaccharide/interferon-gamma injection J Neurosci Res 57 388 398
17. S Gatti T Bartfai 1993 Induction of tumor necrosis factor-alpha mRNA in the brain after peripheral endotoxin treatment: comparison with interleukin-1 family and interleukin-6 Brain Res 624 291 294
18. Y Xia K Yamagata TL Krukoff 2006 Differential expression of the CD14/TLR4 complex and inflammatory signaling molecules following i.c.v. administration of LPS Brain Res 1095 85 95
19. Z Wu Y Hayashi J Zhang 2007 Involvement of prostaglandin E2 released from leptomeningeal cells in increased expression of transforming growth factor-beta in glial cells and cortical neurons during systemic inflammation J Neurosci Res 85 184 192
20. K Fujimori Y Fujitani K Kadoyama 2003 Regulation of lipocalin-type prostaglandin D synthase gene expression by Hes-1 through E-box and interleukin-1 beta via two NF-kappa B elements in rat leptomeningeal cells J Biol Chem 278 6018 6026
21. HR Wickstrom H Holgert T Hokfelt 1999 Birth-related expression of c-fos, c-jun and substance P mRNAs in the rat brainstem and pia mater: possible relationship to changes in central chemosensitivity Brain Res Dev Brain Res 112 255 266
22. HE Humphries M Triantafilou BL Makepeace 2005 Activation of human meningeal cells is modulated by lipopolysaccharide (LPS) and non-LPS components of Neisseria meningitidis and is independent of Toll-like receptor (TLR)4 and TLR2 signalling Cell Microbiol 7 415 430
23. S Chakravarty M Herkenham 2005 Toll-like receptor 4 on nonhematopoietic cells sustains CNS inflammation during endotoxemia, independent of systemic cytokines J Neurosci 25 1788 1796
24. F Mercier GI Hatton 2000 Immunocytochemical basis for a meningeo-glial network J Comp Neurol 420 445 465
25. JJ Baldassare Y Bi CJ Bellone 1999 The role of p38 mitogen-activated protein kinase in IL-1 beta transcription J Immun 162 5367 5373
26. AB Carter MM Monick GW Hunninghake 1999 Both Erk and p38 kinases are necessary for cytokine gene transcription Am J Respir Cell Mol Biol 20 751 758
27. JG Sheng RA Jones XQ Zhou 2001 Interleukin-1 promotion of MAPK-p38 overexpression in experimental animals and in Alzheimer's disease: potential significance for tau protein phosphorylation Neurochem Int 39 341 348
28. SY Park H Lee J Hur 2002 Hypoxia induces nitric oxide production in mouse microglia via p38 mitogen-activated protein kinase pathway Brain Res Mol Brain Res 107 9 16
29. SH Kim CJ Smith LJ Van Eldik 2004 Importance of MAPK pathways for microglial pro-inflammatory cytokine IL-1 beta production Neurobiol Aging 25 431 439
30. A Nadjar C Combe P Busquet 2005 Signaling pathways of interleukin-1 actions in the brain: anatomical distribution of phospho-ERK1/2 in the brain of rat treated systemically with interleukin-1beta Neuroscience 134 921 932
31. G Struckhoff 1995 Cocultures of meningeal and astrocytic cells-a model for the formation of the glial-limiting membrane Int J Dev Neurosci 13 595 606
32. X Wang BR Wang XJ Zhang 2004 Fos expression in the rat brain after intraperitoneal injection of Staphylococcus enterotoxin B and the effect of vagotomy Neurochem Res 29 1667 1674
33. N Quan EL Stern MB Whiteside 1999 Induction of pro-inflammatory cytokine mRNAs in the brain after peripheral injection of subseptic doses of lipopolysaccharide in the rat J Neuroimmunol 93 72 80
34. JA Colombo MI Napp V Puissant 1994 Leptomeningeal and skin fibroblasts: two different cell types? Int J Dev Neurosci 12 57 61
35. C Cao K Matsumura K Yamagata 1996 Endothelial cells of the rat brain vasculature express cyclooxygenase-2 mRNA in response to systemic interleukin-1 beta: a possible site of prostaglandin synthesis responsible for fever Brain Res 733 263 272
36. HE Day H Akil 1996 Differential pattern of c-fos mRNA in rat brain following central and systemic administration of interleukin-1-beta: implications for mechanism of action Neuroendocrinology 63 207 218
37. M Herkenham HY Lee RA Baker 1998 Temporal and spatial patterns of c-fos mRNA induced by intravenous interleukin-1: a cascade of non-neuronal cellular activation at the blood-brain barrier J Comp Neurol 400 175 196
38. T Muraki K Fujimori M Ishizaka 2004 Effects of interleukin-1beta and prostaglandin E2 on prostaglandin D synthase production in cultivated rat leptomeningeal cells J Cereb Blood Flow Metab 24 409 418
39. MG Proescholdt S Chakravarty JA Foster 2002 Intracerebroventricular but not intravenous interleukin-1beta induces widespread vascular-mediated leukocyte infiltration and immune signal mRNA expression followed by brain-wide glial activation Neuroscience 112 731 749
40. J Wieseler-Frank BM Jekich JH Mahoney 2007 A novel immune-to-CNS communication pathway: cells of the meninges surrounding the spinal cord CSF space produce proinflammatory cytokines in response to an inflammatory stimulus Brain Behav Immun 21 711 718
41. P Ghezzi S Sacco D Agnello 2000 LPS induces IL-6 in the brain and in serum largely through TNF production Cytokine 12 1205 1210
42. M Geisterfer J Gauldie 1996 Regulation of signal transducer, GP13O and the LIF receptor in acute inflammation in vivo Cytokine 8 283 287
43. W Thabard M Collette MP Mellerin 2001 IL-6 upregulates its own receptor on some human myeloma cell lines Cytokine 14 352 356
44. M Geisterfer CD Richards J Gauldie 1995 Cytokines oncostatin M and interleukin 1 regulate the expression of the IL-6 receptor (gp80, gp130) Cytokine 7 503 509
45. T Kato H Yamane H Nariuchi 1997 Differential effects of LPS and CD40 ligand stimulations on the induction of IL-12 production by dendritic cells and macrophages Cell Immunol 181 59 67
46. MU Martin H Wesche 2002 Summary and comparison of the signaling mechanisms of the Toll/interleukin-1 receptor family Biochim Biophys Acta 1592 265 280
47. CC Chio YH Chang YW Hsu 2004 PKA-dependent activation of PKC, p38 MAPK and IKK in macrophage: implication in the induction of inducible nitric oxide synthase and interleukin-6 by dibutyryl cAMP Cell Signal 16 565 575
48. H Halfter C Postert M Friedrich 2000 Activation of the Jak-Stat- and MAPK-pathways by oncostatin M is not sufficient to cause growth inhibition of human glioma cells Brain Res Mol Brain Res 80 198 206
49. T Kishimoto S Akira T Taga 1992 IL-6 receptor and mechanism of signal transduction Int J Immunopharmacol 14 431 438
50. IS Lee Y Liu M Narazaki 1997 Vav is associated with signal transducing molecules gp130, Grb2 and Erk2, and is tyrosine phosphorylated in response to interleukin-6 FEBS Lett 401 133 137
51. S Janssens R Beyaert 2003 Functional diversity and regulation of different interleukin-1 receptor-associated kinase (IRAK) family members Mol Cell 11 293 302
52. S Subramaniam C Stansberg C Cunningham 2004 The interleukin 1 receptor family Dev Comp Immunol 28 415 428
53. N Uekawa A Nishikimi K Isobe 2004 Involvement of IL-1 family proteins in p38 linked cellular senescence of mouse embryonic fibroblasts FEBS Lett 575 30 34