Neuroscience: Synaptic patterning by morphogen signaling

Science Signaling

Volumn 1, Issue 18, 2008, Pages

  Williamson, W Ryan ^a   Hiesinger, P Robin ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVIN; DROSOPHILA PROTEIN; DYNACTIN; HORMONE; MICROTUBULE ASSOCIATED PROTEIN;

ANIMAL; BIOLOGICAL MODEL; BRAIN; DROSOPHILA MELANOGASTER; METABOLISM; MORPHOGENESIS; MUTATION; PAPIO; PHYSIOLOGY; REVIEW; SIGNAL TRANSDUCTION; SYNAPSE; TRANSPORT AT THE CELLULAR LEVEL;

ACTIVINS; ANIMALS; BIOLOGICAL TRANSPORT; BODY PATTERNING; BRAIN; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; HORMONES; MICROTUBULE-ASSOCIATED PROTEINS; MODELS, BIOLOGICAL; MUTATION; PAPIO; SIGNAL TRANSDUCTION; SYNAPSES;

EID: 48149102007     PISSN: 19450877     EISSN: 19379145     Source Type: Journal    
DOI: 10.1126/stke.118pe20     Document Type: Review

References (31)

1. Y. Shi, J. Massague, Mechanisms of TGF-beta signaling from cell membrane to the nucleus. Cell 113, 685-700 (2003).
2. P. ten Dijke, C. S. Hill, New insights into TGFbeta- Smad signalling. Trends Biochem. Sci. 29, 265-273 (2004).
3. G. Marqués, Morphogens and synaptogenesis in Drosophila. J. Neurobiol. 64, 417-434 (2005).
4. C. Y. Ting, T. Herman, S. Yonekura, S. Gao, J. Wang, M. Serpe, M. B. O'Connor, S. L. Zipursky, C. H. Lee, Tiling of r7 axons in the Drosophila visual system is mediated both by transduction of an activin signal to the nucleus and by mutual repulsion. Neuron 56, 793-806 (2007).
5. B. J. Dickson, Molecular mechanisms of axon guidance. Science 298, 1959-1964 (2002).
6. M. Yamagata, J. R. Sanes, J. A. Weiner, Synaptic adhesion molecules. Curr. Opin. Cell Biol. 15, 621-632 (2003).
7. F. Charron, M. Tessier-Lavigne, Novel brain wiring functions for classical morphogens: A role as graded positional cues in axon guidance. Development 132, 2251-2262 (2005).
8. R. Salie, V. Niederkofler, S. Arber, Patterning molecules: Multitasking in the nervous system. Neuron 45, 189-192 (2005).
9. L. A. Raftery, V. Twombly, K. Wharton, W. M. Gelbart, Genetic screens to identify elements of the decapentaplegic signaling pathway in Drosophila. Genetics 139, 241-254 (1995).
10. S. DiNardo, J. Heemskerk, S. Dougan, P. H. O'- Farrell, The making of a maggot: Patterning the Drosophila embryonic epidermis. Curr. Opin. Genet. Dev. 4, 529-534 (1994).
11. I. A. Meinertzhagen, T. E. Hanson, (1993). The development of the optic lobe. In The Development of Drosophila Melanogaster, M. Bate and A. Martinez-Arias, Eds. (Cold Spring Harbor, Cold Spring Harbor Press), pp. 1363-1491.
12. T. R. Clandinin, S. L. Zipursky, Making connections in the fly visual system. Neuron 35, 827-841 (2002).
13. C.Y. Ting, C. H. Lee, Visual circuit development in Drosophila. Curr. Opin. Neurobiol. 17, 65-72 (2007).
14. P. R. Hiesinger, R. G. Zhai, Y. Zhou, T. W. Koh, S. Q. Mehta, K. L. Schulze, Y. Cao, P. Verstreken, T. R. Clandinin, K. F. Fischbach, I. A. Meinertzhagen, H. J. Bellen, Activity-independent prespecification of synaptic partners in the visual map of Drosophila. Curr. Biol. 16, 1835-1843 (2006).
15. J. D. Mast, S. Prakash, P. L. Chen, T. R. Clandinin, The mechanisms and molecules that connect photoreceptor axons to their targets in Drosophila. Semin. Cell Dev. Biol. 17, 42-49 (2006).
16. T. Brummel, S. Abdollah, T. E. Haerry, M. J. Shimell, J. Merriam, L. Raftery, J. L. Wrana, M. B. O'Connor, The Drosophila activin receptor baboon signals through dSmad2 and controls cell proliferation but not patterning during larval development. Genes Dev. 13, 98-111 (1999).
17. Z. Xiao, R. Latek, H. F. Lodish, An extended bipartite nuclear localization signal in Smad4 is required for its nuclear import and transcriptional activity. Oncogene 22, 1057-1069 (2003).
18. A. Kurisaki, S. Kose, Y. Yoneda, C. H. Heldin, A. Moustakas, Transforming growth factor-beta induces nuclear import of Smad3 in an importinbeta1 and Ran-dependent manner. Mol. Biol. Cell 12, 1079-1091 (2001).
19. Z. Xiao, X. Liu, H. F. Lodish, Importin beta mediates nuclear translocation of Smad 3. J. Biol. Chem. 275, 23425-23428 (2000).
20. H. B. Chen, J. G. Rud, K. Lin, L. Xu, Nuclear targeting of transforming growth factor-beta-activated Smad complexes. J. Biol. Chem. 280, 21329-21336 (2005).
21. L. Xu, C. Alarcon, S. Col, J. Massague, Distinct domain utilization by Smad3 and Smad4 for nucleoporin interaction and nuclear import. J. Biol. Chem. 278, 42569-42577 (2003).
22. L. Xu, X.Yao, X. Chen, P. Lu, B. Zhang, Y. T. Ip, Msk is required for nuclear import of TGF-β/BMPactivated Smads. J. Cell Biol. 178, 981-994 (2007).
23. C. C. Zhu, J. Q. Boone, P. A. Jensen, S. Hanna, L. Podemski, J. Locke, C. Q. Doe, M. B. O'Connor, Drosophila Activin- and the Activin-like product Dawdle function redundantly to regulate proliferation in the larval brain. Development 135, 513-521 (2008).
24. X. Zheng, J. Wang, T. E. Haerry, A. Y. Wu, J. Martin, M. B. O'Connor, C. H. Lee, T. Lee, TGF-beta signaling activates steroid hormone receptor expression during neuronal remodeling in the Drosophila brain. Cell 112, 303-315 (2003).
25. L. Parker, J. E. Ellis, M. Q. Nguyen, K. Arora, The divergent TGF-beta ligand Dawdle utilizes an activin pathway to influence axon guidance in Drosophila. Development 133, 4981-4991 (2006).
26. M. Serpe, M. B. O'Connor, The metalloprotease tolloid-related and its TGF-beta-like substrate Dawdle regulate Drosophila motoneuron axon guidance. Development 133, 4969-4979 (2006).
27. Z. Wen, J. Q. Zheng, Directional guidance of nerve growth cones. Curr. Opin. Neurobiol. 16, 52-58 (2006).
28. T. E. Kennedy, H. Wang, W. Marshall, M. Tessier- Lavigne, Axon guidance by diffusible chemoattractants: A gradient of netrin protein in the developing spinal cord. J. Neurosci. 26, 8866-8874 (2006).
29. J. A. Ashley, F. N. Katz, Competition and positiondependent targeting in the development of the Drosophila R7 visual projections. Development 120, 1537-1547 (1994).
30. P. R. Hiesinger, C. Reiter, H. Schau, K. F. Fischbach, Neuropil pattern formation and regulation of cell adhesion molecules in Drosophila optic lobe development depend on synaptobrevin. J. Neurosci. 19, 7548-7556 (1999).
31. S. Q. Mehta, P. R. Hiesinger, S. Beronja, R. G. Zhai, K. L. Schulze, P. Verstreken, Y. Cao, Y. Zhou, U. Tepass, M. C. Crair, H. J. Bellen, Mutations in Drosophila sec15 reveal a function in neuronal targeting for a subset of exocyst components. Neuron 46, 219-232 (2005).