Peritoneal Implantation of Cryopreserved Encapsulated Porcine Hepatocytes in Rats Without Immunosuppression: Viability and Function

Transplantation Proceedings

Volumn 40, Issue 6, 2008, Pages 2049-2052

  Baldini, E ^a,b   Cursio, R ^a,b   De Sousa, G ^d   Margara, A ^a,b   Honiger, J ^e   Saint Paul, M C ^c   Bayer, P ^a   Raimondi, V ^a   Rahmani, R ^d   Mouiel, J ^a,b   Gugenheim, J ^a,b  

^a UNIVERSITÉ CÔTE D'AZUR   (France)

^b CENTRE HOSPITALIER UNIVERSITAIRE DE NICE   (France)

^c PASTEUR HOSPITAL   (France)

^d CEMAGREF   (France)

^e INSERM   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ALBUMIN; UREA;

ANIMAL CELL; ARTICLE; BIOLOGICAL ACTIVITY; CELL CULTURE; CELL ENCAPSULATION; CELL FUNCTION; CELL ISOLATION; CELL VIABILITY; CONTROLLED STUDY; CRYOPRESERVATION; FEMALE; HEPATOCYTE TRANSPLANTATION; IMMUNOSUPPRESSIVE TREATMENT; LIVER CELL; MALE; MORPHOLOGY; NONHUMAN; PERITONEUM; PRIORITY JOURNAL; SWINE; ULTRASTRUCTURE; UREA CYCLE;

ANIMALS; CAPSULES; CELL SURVIVAL; CRYOPRESERVATION; FEMALE; GRAFT SURVIVAL; HEPATOCYTES; IMMUNOSUPPRESSION; LIVER, ARTIFICIAL; MALE; PERITONEAL CAVITY; RATS; RATS, INBRED LEW; SWINE; TRANSPLANTATION, HETEROLOGOUS;

EID: 48049096861     PISSN: 00411345     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.transproceed.2008.05.038     Document Type: Article

References (17)

1. Strom S.C., Fisher R.A., Thompson M.T., et al. Hepatocyte transplantation as a bridge to orthotopic liver transplantation in terminal liver failure. Transplantation 63 (1997) 559
2. Strom S.C., Bruzzone P., Cai H., et al. Hepatocyte transplantation: clinical experience and potential for future use. Cell Transplant 5 (2006) S105
3. Fox I.J., and Roy-Chowdhury J. Hepatocyte transplantation. J Hepatol 40 (2004) 878
4. Ebeta H., Oikawa I., and Mito M. Rejection of allogeneic hepatocytes and fetal hepatic tissue transplanted into the spleen. Transplantation 39 (1985) 221
5. Bumgardner G.L., Li J., Heininger M.B., et al. In vivo immune response to allogeneic hepatocytes. Transplant Proc 29 (1997) 2059
6. Darby H., Selden C., and Hodgson H.J. Prolonged survival of cyclosporine-treated allogeneic hepatocellular implants. Transplantation 42 (1986) 325
7. Sarkis R., Benoist S., Honiger J., et al. Transplanted cryopreserved encapsulated porcine hepatocytes are as effective as fresh hepatocytes in preventing death from acute liver failure in rats. Transplantation 70 (2000) 58
8. Guyomard C., Rialland L., Fremond B., et al. Influence of alginate gel entrapment and cryopreservation on survival and xenobiotic metabolism capacity of rat hepatocytes. Toxicol Appl Pharmacol 141 (1996) 349
9. Digit V., Darvasi R., Arthur M., et al. Cryopreserved microencapsulated hepatocytes-transplantation studies in Gunn rats. Transplantation 55 (1993) 616
10. Canaple L., Nurdin N., Angelova N., et al. Maintenance of primary murine hepatocyte functions in multicomponent polymer capsules-in vitro cryopreservation studies. J Hepatol 34 (2001) 11
11. Yuan J., Liu L., Shimada M., et al. Induction, expression and maintenance of cytochrome P450 isoforms in long-term cultures of primary human hepatocytes. ALTEX 21 suppl 3 (2004) 3
12. Guillozo A., Rialland L., Fautrel A., et al. Survival and function of isolated hepatocytes after cryopreservation. Chem Biol Interact 121 (1999) 7
13. Berry M.N., and Friend D.S. High-yield preparation of isolated rat liver parenchymal cells: a biochemical and fine structural study. J Cell Biol 43 (1969) 506
14. Seglen P.O. Preparation of isolated rat liver cells. Method Cell Biol 13 (1976) 23
15. Dou M., De Sousa G., Lacarelle B., et al. Thawed human hepatocytes in primary culture. Cryobiology 29 (1992) 454
16. Honiger J., Balladur P., Mariani P., et al. Permeability and biocompatibility of a new hydrogel used for encapsulation of hepatocytes. Biomaterials 16 (1995) 753
17. Lloyd T.D.R., Orr S., Skett P., et al. Cryopreservation of hepatocytes: a review of current methods for banking. Cell Tissue Bank 4 (2003) 3