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Volumn 27, Issue 14, 2008, Pages 2006-2017

Regulation of the transcription factor Ets-1 by DNA-mediated homo-dimerization

Author keywords

Ets 1; Stromelysin 1 promoter; X ray crystallography

Indexed keywords

DNA; HOMODIMER; MUTANT PROTEIN; STROMELYSIN; TRANSCRIPTION FACTOR ETS 1;

EID: 47949108983     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/emboj.2008.117     Document Type: Article
Times cited : (46)

References (61)
  • 1
    • 19044367561 scopus 로고    scopus 로고
    • Baillat D, Begue A, Stehelin D, Aumercier M (2002) ETS-1 transcription factor binds cooperatively to the palindromic head to head ETS-binding sites of the stromelysin-1 promoter by counteracting autoinhibition. J Biol Chem 277: 29386-29398
    • Baillat D, Begue A, Stehelin D, Aumercier M (2002) ETS-1 transcription factor binds cooperatively to the palindromic head to head ETS-binding sites of the stromelysin-1 promoter by counteracting autoinhibition. J Biol Chem 277: 29386-29398
  • 2
    • 33748941411 scopus 로고    scopus 로고
    • Stromelysin-1 expression is activated in vivo by Ets-1 through palindromic head-to-head Ets binding sites present in the promoter
    • Baillat D, Leprivier G, Regnier D, Vintonenko N, Begue A, Stehelin D, Aumercier M (2006) Stromelysin-1 expression is activated in vivo by Ets-1 through palindromic head-to-head Ets binding sites present in the promoter. Oncogene 25: 5764-5776
    • (2006) Oncogene , vol.25 , pp. 5764-5776
    • Baillat, D.1    Leprivier, G.2    Regnier, D.3    Vintonenko, N.4    Begue, A.5    Stehelin, D.6    Aumercier, M.7
  • 3
    • 0028813664 scopus 로고
    • A direct physical association between ETS and AP-1 transcription factors in normal human T cells
    • Bassuk AG, Leiden JM (1995) A direct physical association between ETS and AP-1 transcription factors in normal human T cells. Immunity 3: 223-237
    • (1995) Immunity , vol.3 , pp. 223-237
    • Bassuk, A.G.1    Leiden, J.M.2
  • 4
    • 0032512459 scopus 로고    scopus 로고
    • The structure of GABPalpha/beta: An ETS domain-ankyrin repeat heterodimer bound to DNA
    • Batchelor AH, Piper DE, de la Brousse FC, McKnight SL, Wolberger C (1998) The structure of GABPalpha/beta: an ETS domain-ankyrin repeat heterodimer bound to DNA. Science 279: 1037-1041
    • (1998) Science , vol.279 , pp. 1037-1041
    • Batchelor, A.H.1    Piper, D.E.2    de la Brousse, F.C.3    McKnight, S.L.4    Wolberger, C.5
  • 6
    • 0348049997 scopus 로고    scopus 로고
    • Ets ternary complex transcription factors
    • Buchwalter G, Gross C, Wasylyk B (2004) Ets ternary complex transcription factors. Gene 324: 1-14
    • (2004) Gene , vol.324 , pp. 1-14
    • Buchwalter, G.1    Gross, C.2    Wasylyk, B.3
  • 7
    • 0030444182 scopus 로고    scopus 로고
    • Erg, an Ets-family member, differentially regulates human collagenase1 (MMP1) and stromelysin1 (MMP3) gene expression by physically interacting with the Fos-Jun complex
    • Buttice G, Duterque-Coquillaud M, Basuyaux JP, Carrere S, Kurkinen M, Stehelin D (1996) Erg, an Ets-family member, differentially regulates human collagenase1 (MMP1) and stromelysin1 (MMP3) gene expression by physically interacting with the Fos-Jun complex. Oncogene 13: 2297-2306
    • (1996) Oncogene , vol.13 , pp. 2297-2306
    • Buttice, G.1    Duterque-Coquillaud, M.2    Basuyaux, J.P.3    Carrere, S.4    Kurkinen, M.5    Stehelin, D.6
  • 8
    • 0027522715 scopus 로고
    • A polyomavirus enhancer A-binding protein-3 site and Ets-2 protein have a major role in the 12-O-tetradecanoylphorbol-13-acetate response of the human stromelysin gene
    • Buttice G, Kurkinen M (1993) A polyomavirus enhancer A-binding protein-3 site and Ets-2 protein have a major role in the 12-O-tetradecanoylphorbol-13-acetate response of the human stromelysin gene. J Biol Chem 268: 7196-7204
    • (1993) J Biol Chem , vol.268 , pp. 7196-7204
    • Buttice, G.1    Kurkinen, M.2
  • 9
    • 0032498230 scopus 로고    scopus 로고
    • The enhanceosome and transcriptional synergy
    • Carey M (1998) The enhanceosome and transcriptional synergy. Cell 92: 5-8
    • (1998) Cell , vol.92 , pp. 5-8
    • Carey, M.1
  • 10
    • 0028103275 scopus 로고
    • The CCP4 suite: Programs for protein crystallography
    • Collaborative Computational Project Number 4
    • Collaborative Computational Project Number 4 (1994) The CCP4 suite: programs for protein crystallography. Acta Crystallogr D Biol Crystallogr 50: 760-763
    • (1994) Acta Crystallogr D Biol Crystallogr , vol.50 , pp. 760-763
  • 11
    • 0034141710 scopus 로고    scopus 로고
    • Phosphorylation represses Ets-1 DNA binding by reinforcing autoinhibition
    • Cowley DO, Graves BJ (2000) Phosphorylation represses Ets-1 DNA binding by reinforcing autoinhibition. Genes Dev 14: 366-376
    • (2000) Genes Dev , vol.14 , pp. 366-376
    • Cowley, D.O.1    Graves, B.J.2
  • 12
    • 0033617408 scopus 로고    scopus 로고
    • Inhibition of Ets-1 DNA binding and ternary complex formation between Ets-1, NF-kappaB, and DNA by a designed DNA-binding ligand
    • Dickinson LA, Trauger JW, Baird EE, Dervan PB, Graves BJ, Gottesfeld JM (1999) Inhibition of Ets-1 DNA binding and ternary complex formation between Ets-1, NF-kappaB, and DNA by a designed DNA-binding ligand. J Biol Chem 274: 12765-12773
    • (1999) J Biol Chem , vol.274 , pp. 12765-12773
    • Dickinson, L.A.1    Trauger, J.W.2    Baird, E.E.3    Dervan, P.B.4    Graves, B.J.5    Gottesfeld, J.M.6
  • 13
    • 2942529276 scopus 로고    scopus 로고
    • The biology of the Ets1 proto-oncogene
    • Dittmer J (2003) The biology of the Ets1 proto-oncogene. Mol Cancer 2: 29
    • (2003) Mol Cancer , vol.2 , pp. 29
    • Dittmer, J.1
  • 15
    • 0027910469 scopus 로고
    • Recognition by Max of its cognate DNA through a dimeric b/HLH/Z domain
    • Ferre-D'Amare AR, Prendergast GC, Ziff EB, Burley SK (1993) Recognition by Max of its cognate DNA through a dimeric b/HLH/Z domain. Nature 363: 38-45
    • (1993) Nature , vol.363 , pp. 38-45
    • Ferre-D'Amare, A.R.1    Prendergast, G.C.2    Ziff, E.B.3    Burley, S.K.4
  • 16
    • 0029833870 scopus 로고    scopus 로고
    • Pax-5 (BSAP) recruits Ets proto-oncogene family proteins to form functional ternary complexes on a Bcell specific promoter
    • Fitzsimmons D, Hodson W, Wheat W, Maira S-M, Wassylyk B, Hagman J (1996) Pax-5 (BSAP) recruits Ets proto-oncogene family proteins to form functional ternary complexes on a Bcell specific promoter. Genes Dev 10: 2198-2211
    • (1996) Genes Dev , vol.10 , pp. 2198-2211
    • Fitzsimmons, D.1    Hodson, W.2    Wheat, W.3    Maira, S.-M.4    Wassylyk, B.5    Hagman, J.6
  • 17
    • 0026504563 scopus 로고
    • Identification of a stromelysin cleavage site within the interglobular domain of human aggrecan. Evidence for proteolysis at this site in vivo in human articular cartilage
    • Flannery CR, Lark MW, Sandy JD (1992) Identification of a stromelysin cleavage site within the interglobular domain of human aggrecan. Evidence for proteolysis at this site in vivo in human articular cartilage. J Biol Chem 267: 1008-1014
    • (1992) J Biol Chem , vol.267 , pp. 1008-1014
    • Flannery, C.R.1    Lark, M.W.2    Sandy, J.D.3
  • 18
    • 0035697276 scopus 로고    scopus 로고
    • Structural studies of Ets-1-Pax5 complex formation on DNA
    • Garvie CW, Hagman J, Wolberger C (2001) Structural studies of Ets-1-Pax5 complex formation on DNA. Mol Cell 8: 1267-1276
    • (2001) Mol Cell , vol.8 , pp. 1267-1276
    • Garvie, C.W.1    Hagman, J.2    Wolberger, C.3
  • 19
    • 0347928848 scopus 로고    scopus 로고
    • Structural analysis of the autoinhibition of Ets-1 and its role in protein partnerships
    • Garvie CW, Pufall MA, Graves BJ, Wolberger C (2002) Structural analysis of the autoinhibition of Ets-1 and its role in protein partnerships. J Biol Chem 277: 45529-45536
    • (2002) J Biol Chem , vol.277 , pp. 45529-45536
    • Garvie, C.W.1    Pufall, M.A.2    Graves, B.J.3    Wolberger, C.4
  • 20
    • 0035930331 scopus 로고    scopus 로고
    • Recognition of specific DNA sequences
    • Garvie CW, Wolberger C (2001) Recognition of specific DNA sequences. Mol Cell 8: 937-946
    • (2001) Mol Cell , vol.8 , pp. 937-946
    • Garvie, C.W.1    Wolberger, C.2
  • 21
    • 0028894384 scopus 로고
    • Crystal structure of the heterodimeric bZIP transcription factor c-Fos-c-Jun bound to DNA
    • Glover JN, Harrison SC (1995) Crystal structure of the heterodimeric bZIP transcription factor c-Fos-c-Jun bound to DNA. Nature 373: 257-261
    • (1995) Nature , vol.373 , pp. 257-261
    • Glover, J.N.1    Harrison, S.C.2
  • 22
    • 0033988443 scopus 로고    scopus 로고
    • Auto-inhibition of Ets-1 is counteracted by DNA binding cooperativity with core-binding factor alpha2
    • Goetz TL, Gu TL, Speck NA, Graves BJ (2000) Auto-inhibition of Ets-1 is counteracted by DNA binding cooperativity with core-binding factor alpha2. Mol Cell Biol 20: 81-90
    • (2000) Mol Cell Biol , vol.20 , pp. 81-90
    • Goetz, T.L.1    Gu, T.L.2    Speck, N.A.3    Graves, B.J.4
  • 23
    • 0033988402 scopus 로고    scopus 로고
    • Auto-inhibition and partner proteins, core-binding factor beta (CBFbeta) and Ets-1, modulate DNA binding by CBFalpha2 (AML1)
    • Gu TL, Goetz TL, Graves BJ, Speck NA (2000) Auto-inhibition and partner proteins, core-binding factor beta (CBFbeta) and Ets-1, modulate DNA binding by CBFalpha2 (AML1). Mol Cell Biol 20: 91-103
    • (2000) Mol Cell Biol , vol.20 , pp. 91-103
    • Gu, T.L.1    Goetz, T.L.2    Graves, B.J.3    Speck, N.A.4
  • 24
    • 0035875907 scopus 로고    scopus 로고
    • The B-box dominates SAP-1-SRF interactions in the structure of the ternary complex
    • Hassler M, Richmond TJ (2001) The B-box dominates SAP-1-SRF interactions in the structure of the ternary complex. EMBO J 20: 3018-3028
    • (2001) EMBO J , vol.20 , pp. 3018-3028
    • Hassler, M.1    Richmond, T.J.2
  • 25
    • 0030053907 scopus 로고    scopus 로고
    • Interaction of ETS-1 and ERGB/FLI-1 proteins with DNA is modulated by spacing between multiple binding sites as well as phosphorylation
    • Hodge DR, Robinson L, Watson D, Lautenberger J, Zhang XK, Venanzoni M, Seth A (1996) Interaction of ETS-1 and ERGB/FLI-1 proteins with DNA is modulated by spacing between multiple binding sites as well as phosphorylation. Oncogene 12: 11-18
    • (1996) Oncogene , vol.12 , pp. 11-18
    • Hodge, D.R.1    Robinson, L.2    Watson, D.3    Lautenberger, J.4    Zhang, X.K.5    Venanzoni, M.6    Seth, A.7
  • 26
    • 34547641224 scopus 로고    scopus 로고
    • Genome-wide analyses reveal properties of redundant and specific promoter occupancy within the ETS gene family
    • Hollenhorst PC, Shah AA, Hopkins C, Graves BJ (2007) Genome-wide analyses reveal properties of redundant and specific promoter occupancy within the ETS gene family. Genes Dev 21: 1882-1894
    • (2007) Genes Dev , vol.21 , pp. 1882-1894
    • Hollenhorst, P.C.1    Shah, A.A.2    Hopkins, C.3    Graves, B.J.4
  • 28
    • 84889120137 scopus 로고
    • Improved methods for building protein models in electron-density maps and the location of errors in these models
    • Jones TA, Zou JY, Cowan SW, Kjeldgaard M (1991) Improved methods for building protein models in electron-density maps and the location of errors in these models.. Acta Crystallogr A 47: 110-119
    • (1991) Acta Crystallogr A , vol.47 , pp. 110-119
    • Jones, T.A.1    Zou, J.Y.2    Cowan, S.W.3    Kjeldgaard, M.4
  • 29
    • 0029958777 scopus 로고    scopus 로고
    • Characterization of the cooperative function of inhibitory sequences in Ets-1
    • Jonsen MD, Petersen JM, Xu QP, Graves BJ (1996) Characterization of the cooperative function of inhibitory sequences in Ets-1. Mol Cell Biol 16: 2065-2073
    • (1996) Mol Cell Biol , vol.16 , pp. 2065-2073
    • Jonsen, M.D.1    Petersen, J.M.2    Xu, Q.P.3    Graves, B.J.4
  • 30
    • 0025729735 scopus 로고
    • The human ETS1 gene: Genomic structure, promoter characterization and alternative splicing
    • Jorcyk CL, Watson DK, Mavrothalassitis GJ, Papas TS (1991) The human ETS1 gene: genomic structure, promoter characterization and alternative splicing. Oncogene 6: 523-532
    • (1991) Oncogene , vol.6 , pp. 523-532
    • Jorcyk, C.L.1    Watson, D.K.2    Mavrothalassitis, G.J.3    Papas, T.S.4
  • 32
    • 0033559972 scopus 로고    scopus 로고
    • Mutual activation of Ets-1 and AML1 DNA binding by direct interaction of their autoinhibitory domains
    • Kim WY, Sieweke M, Ogawa E, Wee HJ, Englmeier U, Graf T, Ito Y (1999) Mutual activation of Ets-1 and AML1 DNA binding by direct interaction of their autoinhibitory domains. EMBO J 18: 1609-1620
    • (1999) EMBO J , vol.18 , pp. 1609-1620
    • Kim, W.Y.1    Sieweke, M.2    Ogawa, E.3    Wee, H.J.4    Englmeier, U.5    Graf, T.6    Ito, Y.7
  • 33
    • 0025328826 scopus 로고
    • Isoforms of the human ets-1 protein: Generation by alternative splicing and differential phosphorylation
    • Koizumi S, Fisher RJ, Fujiwara S, Jorcyk C, Bhat NK, Seth A, Papas TS (1990) Isoforms of the human ets-1 protein: generation by alternative splicing and differential phosphorylation. Oncogene 5: 675-681
    • (1990) Oncogene , vol.5 , pp. 675-681
    • Koizumi, S.1    Fisher, R.J.2    Fujiwara, S.3    Jorcyk, C.4    Bhat, N.K.5    Seth, A.6    Papas, T.S.7
  • 34
    • 13444307044 scopus 로고    scopus 로고
    • Secondary-structure matching (SSM), a new tool for fast protein structure alignment in three dimensions
    • Krissinel E, Henrick K (2004) Secondary-structure matching (SSM), a new tool for fast protein structure alignment in three dimensions. Acta Crystallogr D Biol Crystallogr 60: 2256-2268
    • (2004) Acta Crystallogr D Biol Crystallogr , vol.60 , pp. 2256-2268
    • Krissinel, E.1    Henrick, K.2
  • 36
    • 0242468991 scopus 로고    scopus 로고
    • Man AK, Young LJ, Tynan JA, Lesperance J, Egeblad M, Werb Z, Hauser CA, Muller WJ, Cardiff RD, Oshima RG (2003) Ets2-dependent stromal regulation of mouse mammary tumors. Mol Cell Biol 23: 8614-8625
    • Man AK, Young LJ, Tynan JA, Lesperance J, Egeblad M, Werb Z, Hauser CA, Muller WJ, Cardiff RD, Oshima RG (2003) Ets2-dependent stromal regulation of mouse mammary tumors. Mol Cell Biol 23: 8614-8625
  • 37
    • 0014432781 scopus 로고
    • Solvent content of protein crystals
    • Matthews BW (1968) Solvent content of protein crystals. J Mol Biol 33: 491-497
    • (1968) J Mol Biol , vol.33 , pp. 491-497
    • Matthews, B.W.1
  • 38
    • 0035976797 scopus 로고    scopus 로고
    • Crystal structure of a ternary SAP-1-SRF-c-fos SRE DNA complex
    • Mo Y, Ho W, Johnston K, Marmorstein R (2001) Crystal structure of a ternary SAP-1-SRF-c-fos SRE DNA complex. J Mol Biol 314: 495-506
    • (2001) J Mol Biol , vol.314 , pp. 495-506
    • Mo, Y.1    Ho, W.2    Johnston, K.3    Marmorstein, R.4
  • 39
    • 0037462459 scopus 로고    scopus 로고
    • X-ray structures of Myc-Max and Mad-Max recognizing DNA. Molecular bases of regulation by protooncogenic transcription factors
    • Nair SK, Burley SK (2003) X-ray structures of Myc-Max and Mad-Max recognizing DNA. Molecular bases of regulation by protooncogenic transcription factors. Cell 112: 193-205
    • (2003) Cell , vol.112 , pp. 193-205
    • Nair, S.K.1    Burley, S.K.2
  • 40
    • 0033672187 scopus 로고    scopus 로고
    • Renal expression of the Ets-1 proto-oncogene during progression of rat crescentic glomerulonephritis
    • Naito T, Razzaque MS, Nazneen A, Liu D, Nihei H, Koji T, Taguchi T (2000) Renal expression of the Ets-1 proto-oncogene during progression of rat crescentic glomerulonephritis. J Am Soc Nephrol 11: 2243-2255
    • (2000) J Am Soc Nephrol , vol.11 , pp. 2243-2255
    • Naito, T.1    Razzaque, M.S.2    Nazneen, A.3    Liu, D.4    Nihei, H.5    Koji, T.6    Taguchi, T.7
  • 41
    • 0024377846 scopus 로고
    • Human and rat malignant-tumor-associated mRNAs encode stromelysin-like metalloproteinases
    • Nicholson R, Murphy G, Breathnach R (1989) Human and rat malignant-tumor-associated mRNAs encode stromelysin-like metalloproteinases. Biochemistry 28: 5195-5203
    • (1989) Biochemistry , vol.28 , pp. 5195-5203
    • Nicholson, R.1    Murphy, G.2    Breathnach, R.3
  • 44
  • 45
    • 0038116629 scopus 로고    scopus 로고
    • Choice of data-collection parameters based on statistic modelling
    • Popov AN, Bourenkov GP (2003) Choice of data-collection parameters based on statistic modelling. Acta Crystallogr D Biol Crystallogr 59: 1145-1153
    • (2003) Acta Crystallogr D Biol Crystallogr , vol.59 , pp. 1145-1153
    • Popov, A.N.1    Bourenkov, G.P.2
  • 46
    • 0036441510 scopus 로고    scopus 로고
    • Autoinhibitory domains: Modular effectors of cellular regulation
    • Pufall MA, Graves BJ (2002) Autoinhibitory domains: modular effectors of cellular regulation. Annu Rev Cell Dev Biol 18: 421-462
    • (2002) Annu Rev Cell Dev Biol , vol.18 , pp. 421-462
    • Pufall, M.A.1    Graves, B.J.2
  • 50
    • 0024380087 scopus 로고
    • Rapid detection of octamer binding proteins with 'mini-extracts', prepared from a small number of cells
    • Schreiber E, Matthias P, Muller MM, Schaffner W (1989) Rapid detection of octamer binding proteins with 'mini-extracts', prepared from a small number of cells. Nucleic Acids Res 17: 6419
    • (1989) Nucleic Acids Res , vol.17 , pp. 6419
    • Schreiber, E.1    Matthias, P.2    Muller, M.M.3    Schaffner, W.4
  • 51
    • 0027202560 scopus 로고
    • Transactivation of GATA-1 promoter with ETS1, ETS2 and ERGB/Hu-FLI-1 proteins: Stabilization of the ETS1 protein binding on GATA-1 promoter sequences by monoclonal antibody
    • Seth A, Robinson L, Thompson DM, Watson DK, Papas TS (1993) Transactivation of GATA-1 promoter with ETS1, ETS2 and ERGB/Hu-FLI-1 proteins: stabilization of the ETS1 protein binding on GATA-1 promoter sequences by monoclonal antibody. Oncogene 8: 1783-1790
    • (1993) Oncogene , vol.8 , pp. 1783-1790
    • Seth, A.1    Robinson, L.2    Thompson, D.M.3    Watson, D.K.4    Papas, T.S.5
  • 52
    • 0035515347 scopus 로고    scopus 로고
    • The ETS-domain transcription factor family
    • Sharrocks AD (2001) The ETS-domain transcription factor family. Nat Rev Mol Cell Biol 2: 827-837
    • (2001) Nat Rev Mol Cell Biol , vol.2 , pp. 827-837
    • Sharrocks, A.D.1
  • 54
    • 0032190631 scopus 로고    scopus 로고
    • A transcription factor party during blood cell differentiation
    • Sieweke MH, Graf T (1998) A transcription factor party during blood cell differentiation. Curr Opin Genet Dev 8: 545-551
    • (1998) Curr Opin Genet Dev , vol.8 , pp. 545-551
    • Sieweke, M.H.1    Graf, T.2
  • 55
    • 0029870839 scopus 로고    scopus 로고
    • MafB is an interaction partner and repressor of Ets-1 that inhibits erythroid differentiation
    • Sieweke MH, Tekotte H, Frampton J, Graf T (1996) MafB is an interaction partner and repressor of Ets-1 that inhibits erythroid differentiation. Cell 85: 49-60
    • (1996) Cell , vol.85 , pp. 49-60
    • Sieweke, M.H.1    Tekotte, H.2    Frampton, J.3    Graf, T.4
  • 56
    • 0032536821 scopus 로고    scopus 로고
    • Cooperative interaction of Ets-1 with USF-1 required for HIV-1 enhancer activity in T-cells
    • Sieweke MH, Tekotte H, Jarosch U, Graf T (1998) Cooperative interaction of Ets-1 with USF-1 required for HIV-1 enhancer activity in T-cells. EMBO J 17: 1728-1739
    • (1998) EMBO J , vol.17 , pp. 1728-1739
    • Sieweke, M.H.1    Tekotte, H.2    Jarosch, U.3    Graf, T.4
  • 57
    • 0035119612 scopus 로고    scopus 로고
    • Messenger-RNA expression of matrix metalloproteinases, tissue inhibitors of metalloproteinases, and transcription factors in rheumatic synovial cells under mechanical stimuli
    • Sun HB, Yokota H (2001) Messenger-RNA expression of matrix metalloproteinases, tissue inhibitors of metalloproteinases, and transcription factors in rheumatic synovial cells under mechanical stimuli. Bone 28: 303-309
    • (2001) Bone , vol.28 , pp. 303-309
    • Sun, H.B.1    Yokota, H.2
  • 58
    • 0000560808 scopus 로고    scopus 로고
    • MOLREP: An automated program for molecular replacement
    • Vagin A, Teplyakov A (1997) MOLREP: an automated program for molecular replacement. J Appl Crystallogr 30: 1022-1025
    • (1997) J Appl Crystallogr , vol.30 , pp. 1022-1025
    • Vagin, A.1    Teplyakov, A.2
  • 59
    • 0029883919 scopus 로고    scopus 로고
    • ETS1 and ETS2 in p53 regulation: Spatial separation of ETS binding sites (EBS) modulate protein: DNA interaction
    • Venanzoni MC, Robinson LR, Hodge DR, Kola I, Seth A (1996) ETS1 and ETS2 in p53 regulation: spatial separation of ETS binding sites (EBS) modulate protein: DNA interaction. Oncogene 12: 1199-1204
    • (1996) Oncogene , vol.12 , pp. 1199-1204
    • Venanzoni, M.C.1    Robinson, L.R.2    Hodge, D.R.3    Kola, I.4    Seth, A.5
  • 60
    • 0025809504 scopus 로고
    • The c-Ets oncoprotein activates the stromelysin promoter through the same elements as several non-nuclear oncoproteins
    • Wasylyk C, Gutman A, Nicholson R, Wasylyk B (1991) The c-Ets oncoprotein activates the stromelysin promoter through the same elements as several non-nuclear oncoproteins. EMBO J 10: 1127-1134
    • (1991) EMBO J , vol.10 , pp. 1127-1134
    • Wasylyk, C.1    Gutman, A.2    Nicholson, R.3    Wasylyk, B.4


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