Development of a quantitative real-time TaqMan PCR assay for testing the susceptibility of feline herpesvirus-1 to antiviral compounds

Journal of Virological Methods

Volumn 152, Issue 1-2, 2008, Pages 85-90

  Hussein, Islam T M ^a   Field, Hugh J ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

Antiviral drugs; Feline herpesvirus 1; Real time PCR

Indexed keywords

ACICLOVIR; CIDOFOVIR; PENCICLOVIR; VIRUS DNA;

ANIMAL CELL; ANTIVIRAL SUSCEPTIBILITY; ARTICLE; CAT; FELINE HERPESVIRUS 1; HERPES VIRUS; IC 50; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; VIRUS STRAIN; VIRUS TITRATION;

ACYCLOVIR; ANIMALS; ANTIVIRAL AGENTS; CATS; CELL LINE; INHIBITORY CONCENTRATION 50; KINETICS; MICROBIAL SENSITIVITY TESTS; POLYMERASE CHAIN REACTION; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; VARICELLOVIRUS; VIRUS REPLICATION;

FELID HERPESVIRUS 1; FELIS CATUS;

EID: 47949091165     PISSN: 01660934     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jviromet.2008.05.018     Document Type: Article

References (49)

1. Altschul S.F., Madden T.L., Schaffer A.A., Zhang J., Zhang Z., Miller W., and Lipman D.J. Gapped BLAST and PSI-BLAST: a new generation of protein database search programs. Nucl. Acids Res. 25 (1997) 3389-3402
2. Andrew S.E. Ocular manifestations of feline herpesvirus. J. Feline Med. Surg. 3 (2001) 9-16
3. Arya M., Shergill I.S., Williamson M., Gommersall L., Arya N., and Patel H.R. Basic principles of real-time quantitative PCR. Expert Rev. Mol. Diagn. 5 (2005) 209-219
4. Bacon T.H., Levin M.J., Leary J.J., Sarisky R.T., and Sutton D. Herpes simplex virus resistance to acyclovir and penciclovir after two decades of antiviral therapy. Clin. Microbiol. Rev. 16 (2003) 114-128
5. Block A., and Schwarz G. Validation of different genomic and cloned DNA calibration standards for construct-specific quantification of LibertyLink in rapeseed by real-time PCR. Eur. Food Res. Technol. 216 (2003) 421-427
6. Bustin S.A., and Nolan T. Chemistries. In: Bustin S.A. (Ed). A-Z of Quantitative PCR (2004), International University Line, La Jolla, CA 217-278 (Chapter 6)
7. Bustin S.A., and Nolan T. Data analysis and interpretation. In: Bustin S.A. (Ed). A-Z of Quantitative PCR (2004), International University Line, La Jolla, CA 441-492 (Chapter 11)
8. Coen D.M., and Schaffer P.A. Antiherpesvirus drugs: a promising spectrum of new drugs and drug targets. Nat. Rev. Drug Discov. 2 (2003) 278-288
9. Collins P. The spectrum of antiviral activities of acyclovir in vitro and in vivo. J. Antimicrob. Chemother. 12 Suppl B (1983) 19-27
10. Crandell R.A., and Despeaux E.W. Cytopathology of feline viral rhinotracheitis virus in tissue cultures of feline renal cells. Proc. Soc. Exp. Biol. Med. 101 (1959) 494-497
11. De Clercq E., and Holy A. Acyclic nucleoside phosphonates: a key class of antiviral drugs. Nat. Rev. Drug Discov. 4 (2005) 928-940
12. Elion G.B. Acyclovir: discovery, mechanism of action, and selectivity. J. Med. Virol. Suppl 1 (1993) 2-6
13. Field H.J., and Whitley R.J. Antiviral chemotherapy. In: Mahy B.W.J., and Meulen V. (Eds). Topley & Wilson's Microbiology and Microbial Infections. 10th ed. vol. Virology Volume 2 (2005), Hodder Arnold, London 1605-1645
14. Freeman W.M., Walker S.J., and Vrana K.E. Quantitative RT-PCR: pitfalls and potential. Biotechniques 26 (1999) 112-122 124-5
15. Friedrichs C., Neyts J., Gaspar G., De Clercq E., and Wutzler P. Evaluation of antiviral activity against human herpesvirus 8 (HHV-8) and Epstein-Barr virus (EBV) by a quantitative real-time PCR assay. Antiviral Res. 62 (2004) 121-123
16. Gaskell R. Studies on Feline Viral Rhinotracheitis with Particular Reference to the Carrier State (1975), University of Bristol, Bristol
17. Gaskell R., Dawson S., Radford A., and Thiry E. Feline herpesvirus. Vet. Res. 38 (2007) 337-354
18. Gaskell R., and Willoughby K. Herpesviruses of carnivores. Vet. Microbiol. 69 (1999) 73-88
19. Gunson R., Gillespie G., and Carmen F.W.F. Optimisation of PCR reactions using primer chessboarding. J. Clin. Virol. 26 (2003) 369-373
20. Gunson R.N., Collins T.C., and Carman W.F. Practical experience of high throughput real time PCR in the routine diagnostic virology setting. J. Clin. Virol. 35 (2006) 355-367
21. Helps C., Reeves N., Egan K., Howard P., and Harbour D. Detection of Chlamydophila felis and feline herpesvirus by multiplex real-time PCR analysis. J. Clin. Microbiol. 41 (2003) 2734-2736
22. Hodinka R.L. What clinicians need to know about antiviral drugs and viral resistance. Infect Dis. Clin. North Am. 11 (1997) 945-967
23. Holland P.M., Abramson R.D., Watson R., and Gelfand D.H. Detection of specific polymerase chain reaction product by utilizing the 5′-3′ exonuclease activity of Thermus aquaticus DNA polymerase. Proc. Natl. Acad. Sci. U.S.A. 88 (1991) 7276-7280
24. Hussein I.T.M., Menashy R.V., and Field H.J. Penciclovir is a potent inhibitor of feline herpesvirus-1 with susceptibility determined at the level of virus-encoded thymidine kinase. Antiviral Res. 78 (2008) 268-274
25. Hussein I.T.M., Miguel R.N., Tiley L.S., and Field H.J. Substrate specificity and molecular modelling of the feline herpesvirus-1 thymidine kinase. Arch. Virol. 153 (2008) 495-505
26. Mace M., Manichanh C., Bonnafous P., Precigout S., Boutolleau D., Gautheret-Dejean A., and Agut H. Real-time PCR as a versatile tool for investigating the susceptibility of human herpesvirus 6 to antiviral agents. Antimicrob. Agents Chemother. 47 (2003) 3021-3024
27. Mackay I.M. Real-time PCR in the microbiology laboratory. Clin. Microbiol. Infect. 10 (2004) 190-212
28. Mackay I.M., Arden K.E., and Nitsche A. Real-time PCR in virology. Nucl. Acids Res. 30 (2002) 1292-1305
29. Maeda K., Horimoto T., and Mikami T. Properties and functions of feline herpesvirus type 1 glycoproteins. J. Vet. Med. Sci. 60 (1998) 881-888
30. Maggs D.J. Update on pathogenesis, diagnosis, and treatment of feline herpesvirus type 1. Clin. Tech. Small Anim. Pract. 20 (2005) 94-101
31. Maggs D.J., and Clarke H.E. In vitro efficacy of ganciclovir, cidofovir, penciclovir, foscarnet, idoxuridine, and acyclovir against feline herpesvirus type-1. Am. J. Vet. Res. 65 (2004) 399-403
32. Nasisse M.P., Dorman D.C., Jamison K.C., Weigler B.J., Hawkins E.C., and Stevens J.B. Effects of valacyclovir in cats infected with feline herpesvirus 1. Am. J. Vet. Res. 58 (1997) 1141-1144
33. Nasisse M.P., Guy J.S., Davidson M.G., Sussman W., and De Clercq E. In vitro susceptibility of feline herpesvirus-1 to vidarabine, idoxuridine, trifluridine, acyclovir, or bromovinyldeoxyuridine. Am. J. Vet. Res. 50 (1989) 158-160
34. Niesters H.G. Quantitation of viral load using real-time amplification techniques. Methods 25 (2001) 419-429
35. Owens J.G., Nasisse M.P., Tadepalli S.M., and Dorman D.C. Pharmacokinetics of acyclovir in the cat. J. Vet. Pharmacol. Ther. 19 (1996) 488-490
36. Pillay D. Emergence and control of resistance to antiviral drugs in resistance in herpes viruses, hepatitis B virus, and HIV. Commun. Dis. Public Health 1 (1998) 5-13
37. Ririe K.M., Rasmussen R.P., and Wittwer C.T. Product differentiation by analysis of DNA melting curves during the polymerase chain reaction. Anal. Biochem. 245 (1997) 154-160
38. Roizman B., and Pellett P.E. Herpesviridae. In: Knipe D.M., and Howley P.M. (Eds). Fields Virology (2001), Lippincott Williams & Wilkins, Philadelphia 2381-2397
39. Rozen S., and Skaletsky H. Primer3 on the WWW for general users and for biologist programmers. Methods Mol. Biol. 132 (2000) 365-386
40. Sambrook J., and Russell D.W. Molecular Cloning: A Laboratory Manual (2001), Cold Spring Harbor Laboratory Press, New York
41. Sergerie Y., and Boivin G. Evaluation of susceptibility of human herpesvirus 8 to antiviral drugs by quantitative real-time PCR. J. Clin. Microbiol. 41 (2003) 3897-3900
42. Stiles J. Feline herpesvirus. Clin. Tech. Small Anim. Pract. 18 (2003) 178-185
43. Stranska R., van Loon A.M., Polman M., and Schuurman R. Application of real-time PCR for determination of antiviral drug susceptibility of herpes simplex virus. Antimicrob. Agents Chemother. 46 (2002) 2943-2947
44. Thi T.N., Deback C., Malet I., Bonnafous P., Ait-Arkoub Z., and Agut H. Rapid determination of antiviral drug susceptibility of herpes simplex virus types 1 and 2 by real-time PCR. Antiviral Res. 69 (2006) 152-157
45. Vaerman J.L., Saussoy P., and Ingargiola I. Evaluation of real-time PCR data. J. Biol. Regul. Homeost. Agents 18 (2004) 212-214
46. Vogtlin A., Fraefel C., Albini S., Leutenegger C.M., Schraner E., Spiess B., Lutz H., and Ackermann M. Quantification of feline herpesvirus 1 DNA in ocular fluid samples of clinically diseased cats by real-time TaqMan PCR. J. Clin. Microbiol. 40 (2002) 519-523
47. Watzinger F., Ebner K., and Lion T. Detection and monitoring of virus infections by real-time PCR. Mol. Aspects Med. 27 (2006) 254-298
48. Williams D.L., Fitzmaurice T., Lay L., Forster K., Hefford J., Budge C., Blackmore K., Robinson J.C., and Field H.J. Efficacy of antiviral agents in feline herpetic keratitis: results of an in vitro study. Curr. Eye Res. 29 (2004) 215-218
49. Zuker M. Mfold web server for nucleic acid folding and hybridization prediction. Nucl. Acids Res. 31 (2003) 3406-3415