Exposure to GSM 900 MHz electromagnetic fields affects cerebral cytochrome c oxidase activity

Toxicology

Volumn 250, Issue 1, 2008, Pages 70-74

  Ammari, Mohamed ^a,b   Lecomte, Anthony ^a   Sakly, Mohsen ^b   Abdelmelek, Hafedh ^b   de Seze, René ^a  

^a INSTITUT NATIONAL DE L ENVIRONNEMENT INDUSTRIEL ET DES RISQUES INERIS   (France)

^b University of Carthage   (Tunisia)

Author keywords

Brain; Cytochrome oxidase; GSM 900 MHz; Neuronal activity

Indexed keywords

CYTOCHROME C OXIDASE;

ANIMAL EXPERIMENT; ARTICLE; BRAIN REGION; CONTROLLED STUDY; ELECTROMAGNETIC FIELD; ENVIRONMENTAL EXPOSURE; ENZYME ACTIVITY; MALE; NONHUMAN; PRIORITY JOURNAL; RADIOFREQUENCY RADIATION; RAT;

ANIMALS; BRAIN; CELLULAR PHONE; DOSE-RESPONSE RELATIONSHIP, RADIATION; ELECTROMAGNETIC FIELDS; ELECTRON TRANSPORT COMPLEX IV; MALE; MICROWAVES; NEURONS; RADIATION DOSAGE; RATS; RATS, SPRAGUE-DAWLEY;

RATTUS;

EID: 47849114334     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tox.2008.05.019     Document Type: Article

References (36)

1. Bolanos J.P., Peuchen S., Heales S.J., Land J.M., and Clark J.B. Nitric oxide-mediated inhibition of the mitochondrial respiratory chain in cultured astrocytes. J. Neurochem. 63 (1994) 910-916
2. Borbely A.A., Huber R., Graf T., Fuchs B., Gallmann E., and Achermann P. Pulsed high-frequency electromagnetic field affects human sleep and sleep electroencephalogram. Neurosci. Lett. 275 (1999) 207-210
3. Brillaud E., Morillion D., and de Seze R. Modest environmental enrichment: effect on a radial maze validation and well being of rats. Brain Res. 1054 (2005) 174-182
4. Brillaud E., Piotrowski A., and de Seze R. Effect of an acute 900 MHz GSM exposure on glia in the rat brain: a time-dependent study. Toxicology 238 (2007) 23-33
5. Brorson J.R., Schumacker P.T., and Zhang H. Nitric oxide acutely inhibits neuronal energy production. The Committees on Neurobiology and Cell Physiology. J. Neurosci. 19 (1999) 147-158
6. Bullitt E. Expression of c-fos-like protein as a marker for neuronal activity following noxious stimulation in the rat. J. Comp. Neurol. 296 (1990) 517-530
7. D'Andrea J.A., Chou C.K., Johnston S.A., and Adair E.R. Microwave effects on the nervous system. Bioelectromagnetics suppl. 6 (2003) S107-S147
8. Dasdag S., Zulkuf Akdag M., Aksen F., Yilmaz F., Bashan M., Mutlu Dasdag M., and Salih Celik M. Whole body exposure of rats to microwaves emitted from a cell phone does not affect the testes. Bioelectromagnetics 24 (2003) 182-188
9. Dubreuil D., Jay T., and Edeline J.M. Does head-only exposure to GSM-900 electromagnetic fields affect the performance of rats in spatial learning tasks?. Behav. Brain Res. 129 (2002) 203-210
10. Eulitz C., Ullsperger P., Freude G., and Elbert T. Mobile phones modulate response patterns of human brain activity. Neuroreport 9 (1998) 3229-3232
11. Finnie J.W. Expression of the immediate early gene, c-fos, in mouse brain after acute global system for mobile communication microwave exposure. Pathology 37 (2005) 231-233
12. Gonzalez-Lima F., and Jones D. Quantitative mapping of cytochrome oxidase activity in the central auditory system of the gerbil: a study with calibrated activity standards and metal-intensified histochemistry. Brain Res. 660 (1994) 34-49
13. Hermann D.M., and Hossmann K.A. Neurological effects of microwave exposure related to mobile communication. J. Neurol. Sci. 152 (1997) 1-14
14. Herrera D.G., and Robertson H.A. Activation of c-fos in the brain. Prog. Neurobiol. 50 (1996) 83-107
15. Hinrikus H., Bachmann M., Lass J., Tomson R., and Tuulik V. Effect of 7, 14 and 21 Hz modulated 450 MHz microwave radiation on human electroencephalographic rhythms. Int. J. Radiat. Biol. 84 (2008) 69-79
16. Ilhan A., Gurel A., Armutcu F., Kamisli S., Iraz M., Akyol O., and Ozen S. Ginkgo biloba prevents mobile phone-induced oxidative stress in rat brain. Clin. Chim. Acta 340 (2004) 153-162
17. Inaba R., Shishido K., Okada A., and Moroji T. Effects of whole body microwave exposure on the rat brain contents of biogenic amines. Eur. J. Appl. Physiol. Occup. Physiol. 65 (1992) 124-128
18. Kellenyi L., Thuroczy G., Faludy B., and Lenard L. Effects of mobile GSM radiotelephone exposure on the auditory brainstem response (ABR). Neurobiology (Bp) 7 (1999) 79-81
19. Krause C.M., Haarala C., Sillanmaki L., Koivisto M., Alanko K., Revonsuo A., Laine M., and Hamalainen H. Effects of electromagnetic field emitted by cellular phones on the EEG during an auditory memory task: a double blind replication study. Bioelectromagnetics 25 (2004) 33-40
20. Lai H., Horita A., Chou C.K., and Guy A.W. Low-level microwave irradiations affect central cholinergic activity in the rat. J. Neurochem. 48 (1987) 40-45
21. Lai H., Carino M.A., Horita A., and Guy A.W. Low-level microwave irradiation and central cholinergic systems. Pharmacol. Biochem. Behav. 33 (1989) 131-138
22. Lai H., Carino M.A., Horita A., and Guy A.W. Corticotropin-releasing factor antagonist blocks microwave-induced decreases in high-affinity choline uptake in the rat brain. Brain Res. Bull. 25 (1990) 609-612
23. Maby E., Le Bouquin Jeannes R., Liegeois-Chauvel C., Gourevitch B., and Faucon G. Analysis of auditory evoked potential parameters in the presence of radiofrequency fields using a support vector machines method. Med. Biol. Eng. Comput. 42 (2004) 562-568
24. Mausset A.L., de Seze R., Montpeyroux F., and Privat A. Effects of radiofrequency exposure on the GABAergic system in the rat cerebellum: clues from semi-quantitative immunohistochemistry. Brain Res. 912 (2001) 33-46
25. Mausset-Bonnefont A.L., Hirbec H., Bonnefont X., Privat A., Vignon J., and de Seze R. Acute exposure to GSM 900-MHz electromagnetic fields induces glial reactivity and biochemical modifications in the rat brain. Neurobiol. Dis. 17 (2004) 445-454
26. Merritt J.H., Chamness A.F., Hartzell R.H., and Allen S.J. Orientation effects on microwave-induced hyperthermia and neurochemical correlates. J. Microw. Power 12 (1977) 167-172
27. Millar D.B., Christopher J.P., Hunter J., and Yeandle S.S. The effect of exposure of acetylcholinesterase to 2,450-MHz microwave radiation. Bioelectromagnetics 5 (1984) 165-172
28. Modak A.T., Stavinoha W.B., and Deam A.P. Effect of short electromagnetic pulses on brain acetylcholine content and spontaneous motor activity of mice. Bioelectromagnetics 2 (1981) 89-92
29. Paxinos G., and Watson C. The Rat Brain in Stereotaxic Coordinates. (4th Edition ed.) (1998), Academic Press, London
30. Schonborn F., Burkhardt M., and Kuster N. Differences in energy absorption between heads of adults and children in the near field of sources. Health Phys. 74 (1998) 160-168
31. Schweizer M., and Richter C. Nitric oxide potently and reversibly deenergizes mitochondria at low oxygen tension. Biochem. Biophys. Res. Commun. 204 (1994) 169-175
32. Strazielle C., Kremarik P., Ghersi-Egea J.F., and Lalonde R. Regional brain variations of cytochrome oxidase activity and motor coordination in Lurcher mutant mice. Exp. Brain Res. 121 (1998) 35-45
33. Wong-Riley M. Changes in the visual system of monocularly sutured or enucleated cats demonstrable with cytochrome oxidase histochemistry. Brain Res. 171 (1979) 11-28
34. Wong-Riley M.T. Cytochrome oxidase: an endogenous metabolic marker for neuronal activity. Trends Neurosci. 12 (1989) 94-101
35. Xu S., Ning W., Xu Z., Zhou S., Chiang H., and Luo J. Chronic exposure to GSM 1800-MHz microwaves reduces excitatory synaptic activity in cultured hippocampal neurons. Neurosci. Lett. 398 (2006) 253-257
36. Zhang J., Dawson V.L., Dawson T.M., and Snyder S.H. Nitric oxide activation of poly(ADP-ribose) synthetase in neurotoxicity. Science 263 (1994) 687-689