-
1
-
-
33748127203
-
Chemopreventive effects of dietary flaxseed on colon tumor development
-
Bommareddy A, Arasada BL, Mathees DP, Dwivedi C. Chemopreventive effects of dietary flaxseed on colon tumor development. Nutr Cancer 2006; 54: 216-222
-
(2006)
Nutr Cancer
, vol.54
, pp. 216-222
-
-
Bommareddy, A.1
Arasada, B.L.2
Mathees, D.P.3
Dwivedi, C.4
-
2
-
-
34249856354
-
Cyclooxygenase-2 expression after preoperative chemoradiotherapy correlates with more frequent esophageal cancer recurrence
-
Yoshikawa R, Fujiwara Y, Koishi K, Kojima S, Matsumoto T, Yanagi H, Yamamura T, Hashimoto-Tamaoki T, Nishigami T, Tsujimura T. Cyclooxygenase-2 expression after preoperative chemoradiotherapy correlates with more frequent esophageal cancer recurrence. World J Gastroenterol 2007; 13: 2283-2288
-
(2007)
World J Gastroenterol
, vol.13
, pp. 2283-2288
-
-
Yoshikawa, R.1
Fujiwara, Y.2
Koishi, K.3
Kojima, S.4
Matsumoto, T.5
Yanagi, H.6
Yamamura, T.7
Hashimoto-Tamaoki, T.8
Nishigami, T.9
Tsujimura, T.10
-
3
-
-
26444548179
-
Differential effects of COX inhibitors against beta-amyloid-induced neurotoxicity in human neuroblastoma cells
-
Ferrera P, Arias C. Differential effects of COX inhibitors against beta-amyloid-induced neurotoxicity in human neuroblastoma cells. Neurochem Int 2005; 47: 589-596
-
(2005)
Neurochem Int
, vol.47
, pp. 589-596
-
-
Ferrera, P.1
Arias, C.2
-
4
-
-
33845199658
-
Inhibition of 5-lipoxygenase by MK886 augments the antitumor activity of celecoxib in human colon cancer cells
-
Cianchi F, Cortesini C, Magnelli L, Fanti E, Papucci L, Schiavone N, Messerini L, Vannacci A, Capaccioli S, Perna F, Lulli M, Fabbroni V, Perigli G, Bechi P, Masini E. Inhibition of 5-lipoxygenase by MK886 augments the antitumor activity of celecoxib in human colon cancer cells. Mol Cancer Ther 2006; 5: 2716-2726
-
(2006)
Mol Cancer Ther
, vol.5
, pp. 2716-2726
-
-
Cianchi, F.1
Cortesini, C.2
Magnelli, L.3
Fanti, E.4
Papucci, L.5
Schiavone, N.6
Messerini, L.7
Vannacci, A.8
Capaccioli, S.9
Perna, F.10
Lulli, M.11
Fabbroni, V.12
Perigli, G.13
Bechi, P.14
Masini, E.15
-
5
-
-
47849088870
-
Expression of 5-lipoxygenase in pancreatic cancer and its clinical significance
-
Zhang B, Shi XT, Yi LH, Li ZY, Yu JM. Expression of 5-lipoxygenase in pancreatic cancer and its clinical significance. Zhonghua Zhongliu Fangzhi Zazhi 2004; 11: 68-70
-
(2004)
Zhonghua Zhongliu Fangzhi Zazhi
, vol.11
, pp. 68-70
-
-
Zhang, B.1
Shi, X.T.2
Yi, L.H.3
Li, Z.Y.4
Yu, J.M.5
-
6
-
-
22444437119
-
Effects of selective COX-2 and 5-LOX inhibition on prostaglandin and leukotriene synthesis in ductal pancreatic cancer in Syrian hamster
-
Gregor JI, Kilian M, Heukamp I, Kiewert C, Kristiansen G, Schimke I, Walz MK, Jacobi CA, Wenger FA. Effects of selective COX-2 and 5-LOX inhibition on prostaglandin and leukotriene synthesis in ductal pancreatic cancer in Syrian hamster. Prostaglandins Leukot Essent Fatty Acids 2005; 73: 89-97
-
(2005)
Prostaglandins Leukot Essent Fatty Acids
, vol.73
, pp. 89-97
-
-
Gregor, J.I.1
Kilian, M.2
Heukamp, I.3
Kiewert, C.4
Kristiansen, G.5
Schimke, I.6
Walz, M.K.7
Jacobi, C.A.8
Wenger, F.A.9
-
7
-
-
34249065795
-
Simultaneous inhibition of COX-2 and 5-LOX activities augments growth arrest and death of premalignant and malignant human lung cell lines
-
Schroeder CP, Yang P, Newman RA, Lotan R. Simultaneous inhibition of COX-2 and 5-LOX activities augments growth arrest and death of premalignant and malignant human lung cell lines. J Exp Ther Oncol 2007; 6: 183-192
-
(2007)
J Exp Ther Oncol
, vol.6
, pp. 183-192
-
-
Schroeder, C.P.1
Yang, P.2
Newman, R.A.3
Lotan, R.4
-
8
-
-
34047216368
-
Dynamic simulations on the arachidonic acid metabolic network
-
Yang K, Ma W, Liang H, Ouyang Q, Tang C, Lai L. Dynamic simulations on the arachidonic acid metabolic network. PLoS Comput Biol 2007; 3: e55
-
(2007)
PLoS Comput Biol
, vol.3
-
-
Yang, K.1
Ma, W.2
Liang, H.3
Ouyang, Q.4
Tang, C.5
Lai, L.6
-
9
-
-
33747875667
-
Involvement of the 5-lipoxygenase/leukotriene A4 hydrolase pathway in 7,12-dimethylbenz[a]anthracene (DMBA)-induced oral carcinogenesis in hamster cheek pouch, and inhibition of carcinogenesis by its inhibitors
-
Sun Z, Sood S, Li N, Ramji D, Yang P, Newman RA, Yang CS, Chen X. Involvement of the 5-lipoxygenase/leukotriene A4 hydrolase pathway in 7,12-dimethylbenz[a]anthracene (DMBA)-induced oral carcinogenesis in hamster cheek pouch, and inhibition of carcinogenesis by its inhibitors. Carcinogenesis 2006; 27: 1902-1908
-
(2006)
Carcinogenesis
, vol.27
, pp. 1902-1908
-
-
Sun, Z.1
Sood, S.2
Li, N.3
Ramji, D.4
Yang, P.5
Newman, R.A.6
Yang, C.S.7
Chen, X.8
-
10
-
-
0037378120
-
Leukotriene synthesis by epithelial cells
-
Luo M, Lee S, Brock TG. Leukotriene synthesis by epithelial cells. Histol Histopathol 2003; 18: 587-595
-
(2003)
Histol Histopathol
, vol.18
, pp. 587-595
-
-
Luo, M.1
Lee, S.2
Brock, T.G.3
-
11
-
-
33845874155
-
-
Vidal C, Gomez-Hernandez A, Sanchez-Galan E, Gonzalez A, Ortega L, Gomez-Gerique JA, Tunon J, Egido J. Licofelone, a balanced inhibitor of cyclooxygenase and 5-lipoxygenase, reduces inflammation in a rabbit model of atherosclerosis. J Pharmacol Exp Ther 2007; 320: 108-116
-
Vidal C, Gomez-Hernandez A, Sanchez-Galan E, Gonzalez A, Ortega L, Gomez-Gerique JA, Tunon J, Egido J. Licofelone, a balanced inhibitor of cyclooxygenase and 5-lipoxygenase, reduces inflammation in a rabbit model of atherosclerosis. J Pharmacol Exp Ther 2007; 320: 108-116
-
-
-
-
12
-
-
0038167016
-
The deregulation of arachidonic acid metabolism-related genes in human esophageal squamous cell carcinoma
-
Zhi H, Zhang J, Hu G, Lu J, Wang X, Zhou C, Wu M, Liu Z. The deregulation of arachidonic acid metabolism-related genes in human esophageal squamous cell carcinoma. Int J Cancer 2003; 106: 327-3233
-
(2003)
Int J Cancer
, vol.106
, pp. 327-3233
-
-
Zhi, H.1
Zhang, J.2
Hu, G.3
Lu, J.4
Wang, X.5
Zhou, C.6
Wu, M.7
Liu, Z.8
-
13
-
-
0038399865
-
Prevention of thrombosis and vascular inflammation: Benefits and limitations of selective or combined COX-1, COX-2 and 5-LOX inhibitors
-
de Gaetano G, Donati MB, Cerletti C. Prevention of thrombosis and vascular inflammation: benefits and limitations of selective or combined COX-1, COX-2 and 5-LOX inhibitors. Trends Pharmacol Sci 2003; 24: 245-252
-
(2003)
Trends Pharmacol Sci
, vol.24
, pp. 245-252
-
-
de Gaetano, G.1
Donati, M.B.2
Cerletti, C.3
-
14
-
-
0038147318
-
Therapeutic role of dual inhibitors of 5-LOX and COX, selective and non-selective non-steroidal anti-inflammatory drugs
-
Martel-Pelletier J, Lajeunesse D, Reboul P, Pelletier JP. Therapeutic role of dual inhibitors of 5-LOX and COX, selective and non-selective non-steroidal anti-inflammatory drugs. Ann Rheum Dis 2003; 62: 501-509
-
(2003)
Ann Rheum Dis
, vol.62
, pp. 501-509
-
-
Martel-Pelletier, J.1
Lajeunesse, D.2
Reboul, P.3
Pelletier, J.P.4
-
15
-
-
33846217715
-
5-LOX inhibitor modulates the inflammatory responses provoked by Helicobacter pylori infection
-
Park S, Han SU, Lee KM, Park KH, Cho SW, Hahm KB. 5-LOX inhibitor modulates the inflammatory responses provoked by Helicobacter pylori infection. Helicobacter 2007; 12: 49-58
-
(2007)
Helicobacter
, vol.12
, pp. 49-58
-
-
Park, S.1
Han, S.U.2
Lee, K.M.3
Park, K.H.4
Cho, S.W.5
Hahm, K.B.6
-
16
-
-
0035873134
-
Depth of invasion parallels increased cyclooxygenase-2 levels in patients with gastric carcinoma
-
Ohno R, Yoshinaga K, Fujita T, Hasegawa K, Iseki H, Tsunozaki H, Ichikawa W, Nihei Z, Sugihara K. Depth of invasion parallels increased cyclooxygenase-2 levels in patients with gastric carcinoma. Cancer 2001; 91: 1876-1881
-
(2001)
Cancer
, vol.91
, pp. 1876-1881
-
-
Ohno, R.1
Yoshinaga, K.2
Fujita, T.3
Hasegawa, K.4
Iseki, H.5
Tsunozaki, H.6
Ichikawa, W.7
Nihei, Z.8
Sugihara, K.9
-
17
-
-
34248551185
-
Effect of chronic CB1 cannabinoid receptor antagonism on livers of rats with biliary cirrhosis
-
Yang YY, Lin HC, Huang YT, Lee TY, Hou MC, Wang YW, Lee FY, Lee SD. Effect of chronic CB1 cannabinoid receptor antagonism on livers of rats with biliary cirrhosis. Clin Sci (Lond) 2007; 112: 533-542
-
(2007)
Clin Sci (Lond)
, vol.112
, pp. 533-542
-
-
Yang, Y.Y.1
Lin, H.C.2
Huang, Y.T.3
Lee, T.Y.4
Hou, M.C.5
Wang, Y.W.6
Lee, F.Y.7
Lee, S.D.8
-
18
-
-
33845929842
-
Co-administration of acetyl-11-keto-beta-boswellic acid, a specific 5-lipoxygenase inhibitor, potentiates the protective effect of COX-2 inhibitors in kainic acid-induced neurotoxicity in mice
-
Bishnoi M, Patil CS, Kumar A, Kulkarni SK. Co-administration of acetyl-11-keto-beta-boswellic acid, a specific 5-lipoxygenase inhibitor, potentiates the protective effect of COX-2 inhibitors in kainic acid-induced neurotoxicity in mice. Pharmacology 2007; 79: 34-41
-
(2007)
Pharmacology
, vol.79
, pp. 34-41
-
-
Bishnoi, M.1
Patil, C.S.2
Kumar, A.3
Kulkarni, S.K.4
-
19
-
-
33748337332
-
Chemical constituents of the root of Dystaenia takeshimana and their anti-inflammatory activity
-
Kim JS, Kim JC, Shim SH, Lee EJ, Jin W, Bae K, Son KH, Kim HP, Kang SS, Chang HW. Chemical constituents of the root of Dystaenia takeshimana and their anti-inflammatory activity. Arch Pharm Res 2006; 29: 617-623
-
(2006)
Arch Pharm Res
, vol.29
, pp. 617-623
-
-
Kim, J.S.1
Kim, J.C.2
Shim, S.H.3
Lee, E.J.4
Jin, W.5
Bae, K.6
Son, K.H.7
Kim, H.P.8
Kang, S.S.9
Chang, H.W.10
-
20
-
-
15644368833
-
New cyclooxygenase-2/5-lipoxygenase inhibitors. 3. 7-tert-butyl-2, 3-dihydro-3,3-dimethylbenzofuran derivatives as gastrointestinal safe antiinflammatory and analgesic agents: Variations at the 5 position
-
Janusz JM, Young PA, Ridgeway JM, Scherz MW, Enzweiler K, Wu LI, Gan L, Chen J, Kellstein DE, Green SA, Tulich JL, Rosario-Jansen T, Magrisso IJ, Wehmeyer KR, Kuhlenbeck DL, Eichhold TH, Dobson RL. New cyclooxygenase-2/5-lipoxygenase inhibitors. 3. 7-tert-butyl-2, 3-dihydro-3,3-dimethylbenzofuran derivatives as gastrointestinal safe antiinflammatory and analgesic agents: variations at the 5 position. J Med Chem 1998; 41: 3515-3529
-
(1998)
J Med Chem
, vol.41
, pp. 3515-3529
-
-
Janusz, J.M.1
Young, P.A.2
Ridgeway, J.M.3
Scherz, M.W.4
Enzweiler, K.5
Wu, L.I.6
Gan, L.7
Chen, J.8
Kellstein, D.E.9
Green, S.A.10
Tulich, J.L.11
Rosario-Jansen, T.12
Magrisso, I.J.13
Wehmeyer, K.R.14
Kuhlenbeck, D.L.15
Eichhold, T.H.16
Dobson, R.L.17
-
21
-
-
33646485914
-
Essential structural profile of a dual functional inhibitor against cyclooxygenase-2 (COX-2) and 5-lipoxygenase (5-LOX): Molecular docking and 3D-QSAR analyses on DHDMBF analogues
-
Zheng M, Zhang Z, Zhu W, Liu H, Luo X, Chen K, Jiang H. Essential structural profile of a dual functional inhibitor against cyclooxygenase-2 (COX-2) and 5-lipoxygenase (5-LOX): molecular docking and 3D-QSAR analyses on DHDMBF analogues. Bioorg Med Chem 2006; 14: 3428-3437
-
(2006)
Bioorg Med Chem
, vol.14
, pp. 3428-3437
-
-
Zheng, M.1
Zhang, Z.2
Zhu, W.3
Liu, H.4
Luo, X.5
Chen, K.6
Jiang, H.7
-
22
-
-
0036774774
-
Inhibitory activity of tryptanthrin on prostaglandin and leukotriene synthesis
-
Danz H, Stoyanova S, Thomet OA, Simon HU, Dannhardt G, Ulbrich H, Hamburger M. Inhibitory activity of tryptanthrin on prostaglandin and leukotriene synthesis. Planta Med 2002; 68: 875-880
-
(2002)
Planta Med
, vol.68
, pp. 875-880
-
-
Danz, H.1
Stoyanova, S.2
Thomet, O.A.3
Simon, H.U.4
Dannhardt, G.5
Ulbrich, H.6
Hamburger, M.7
-
23
-
-
33750497844
-
Inflammation and cancer: How hot is the link?
-
Aggarwal BB, Shishodia S, Sandur SK, Pandey MK, Sethi G. Inflammation and cancer: how hot is the link? Biochem Pharmacol 2006; 72: 1605-1621
-
(2006)
Biochem Pharmacol
, vol.72
, pp. 1605-1621
-
-
Aggarwal, B.B.1
Shishodia, S.2
Sandur, S.K.3
Pandey, M.K.4
Sethi, G.5
-
24
-
-
33745591142
-
Effect of arachidonic and eicosapentaenoic acid metabolism on RAW 264.7 macrophage proliferation
-
Nieves D, Moreno JJ. Effect of arachidonic and eicosapentaenoic acid metabolism on RAW 264.7 macrophage proliferation. J Cell Physiol 2006; 208: 428-434
-
(2006)
J Cell Physiol
, vol.208
, pp. 428-434
-
-
Nieves, D.1
Moreno, J.J.2
-
25
-
-
33847051340
-
Risk of upper gastrointestinal complications among users of traditional NSAIDs and COXIBs in the general population
-
Garcia Rodriguez LA, Barreales Tolosa L. Risk of upper gastrointestinal complications among users of traditional NSAIDs and COXIBs in the general population. Gastroenterology 2007; 132: 498-506
-
(2007)
Gastroenterology
, vol.132
, pp. 498-506
-
-
Garcia Rodriguez, L.A.1
Barreales Tolosa, L.2
-
27
-
-
33750975081
-
Identification of specific genes and pathways involved in NSAIDs-induced apoptosis of human colon cancer cells
-
Huang RH, Chai J, Tarnawski AS. Identification of specific genes and pathways involved in NSAIDs-induced apoptosis of human colon cancer cells. World J Gastroenterol 2006; 12: 6446-6452
-
(2006)
World J Gastroenterol
, vol.12
, pp. 6446-6452
-
-
Huang, R.H.1
Chai, J.2
Tarnawski, A.S.3
-
28
-
-
0038718727
-
Relative contribution of acetylated cyclo-oxygenase (COX)-2 and 5-lipooxygenase (LOX) in regulating gastric mucosal integrity and adaptation to aspirin
-
Fiorucci S, Distrutti E, de Lima OM, Romano M, Mencarelli A, Barbanti M, Palazzini E, Morelli A, Wallace JL. Relative contribution of acetylated cyclo-oxygenase (COX)-2 and 5-lipooxygenase (LOX) in regulating gastric mucosal integrity and adaptation to aspirin. FASEB J 2003; 17: 1171-1173
-
(2003)
FASEB J
, vol.17
, pp. 1171-1173
-
-
Fiorucci, S.1
Distrutti, E.2
de Lima, O.M.3
Romano, M.4
Mencarelli, A.5
Barbanti, M.6
Palazzini, E.7
Morelli, A.8
Wallace, J.L.9
-
29
-
-
0035554401
-
Cyclooxygenases and lipoxygenases as potential targets for treatment of pancreatic cancer
-
Ding XZ, Tong WG, Adrian TE. Cyclooxygenases and lipoxygenases as potential targets for treatment of pancreatic cancer. Pancreatology 2001; 1: 291-299
-
(2001)
Pancreatology
, vol.1
, pp. 291-299
-
-
Ding, X.Z.1
Tong, W.G.2
Adrian, T.E.3
-
30
-
-
0035584272
-
Dual inhibitors of cyclooxygenase and 5-lipoxygenase. A new avenue in antiinflammatory therapy?
-
Fiorucci S, Meli R, Bucci M, Cirino G. Dual inhibitors of cyclooxygenase and 5-lipoxygenase. A new avenue in antiinflammatory therapy? Biochem Pharmacol 2001; 62: 1433-1438
-
(2001)
Biochem Pharmacol
, vol.62
, pp. 1433-1438
-
-
Fiorucci, S.1
Meli, R.2
Bucci, M.3
Cirino, G.4
|