Co-administration of acetyl-11-keto-β-boswellic acid, a specific 5-lipoxygenase inhibitor, potentiates the protective effect of COX-2 inhibitors in kainic acid-induced neurotoxicity in mice

Pharmacology

Volumn 79, Issue 1, 2007, Pages 34-41

  Bishnoi, Mahendra ^a   Patil, C S ^a   Kumar, Anil ^a   Kulkarni, Shrinivas K ^a  

^a PANJAB UNIVERSITY   (India)

Author keywords

Cyclooxygenase inhibitors; Excitotoxicity, kainic acid; Kainic acid, excitotoxicity; Lipoxygenase inhibitors

Indexed keywords

ACETYL 11 OXO BETA BOSWELLIC ACID; BOSWELLIC ACID; CYCLOOXYGENASE 2 INHIBITOR; INDOMETACIN; KAINIC ACID; NIMESULIDE; ROFECOXIB; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIOXIDANT ACTIVITY; ARTICLE; CLONIC SEIZURE; CONTROLLED STUDY; DRUG POTENTIATION; EXCITOTOXICITY; LATENT PERIOD; MALE; MORTALITY; MOUSE; NEUROTOXICITY; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT;

ADMINISTRATION, ORAL; ANIMALS; ANTINEMATODAL AGENTS; ARACHIDONATE 5-LIPOXYGENASE; BRAIN; CATALASE; CYCLOOXYGENASE 2 INHIBITORS; DRUG SYNERGISM; DRUG THERAPY, COMBINATION; EPILEPSY, TONIC-CLONIC; GLUTATHIONE; INDOMETHACIN; INJECTIONS, INTRAPERITONEAL; KAINIC ACID; LACTONES; LIPID PEROXIDATION; MALE; MICE; MICE, INBRED STRAINS; NITRIC OXIDE; PEROXIDASE; SULFONAMIDES; SULFONES; TRITERPENES;

EID: 33845929842     PISSN: 00317012     EISSN: None     Source Type: Journal    
DOI: 10.1159/000097627     Document Type: Article

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