Acute toxicity of βγ-CAT, a naturally existing non-lens βγ-crystallin and trefoil factor complex from frog Bombina maxima skin secretions

Toxicon

Volumn 52, Issue 1, 2008, Pages 22-31

  Qian, Jin Qiao ^a,b,c   Liu, Shu Bai ^a,c   He, Ying Ying ^a,c   Lee, Wen Hui ^a   Zhang, Yun ^a  

^a KUNMING INSTITUTE OF ZOOLOGY   (China)

^b KUNMING MEDICAL UNIVERSITY   (China)

^c UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

Author keywords

CAT; Amphibian; Cardiovascular collapse; Non lens crystallin; Toxicity; Trefoil factor

Indexed keywords

ASPARTATE AMINOTRANSFERASE; BETA CRYSTALLIN; GAMMA CRYSTALLIN; GLUCOSE; LACTATE DEHYDROGENASE; CRYSTALLIN; CYTOKINE; PEPTIDE; TREFOIL FACTOR;

ACUTE TOXICITY; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLEEDING; BODY WEIGHT; CONTROLLED STUDY; ENZYME BLOOD LEVEL; FEMALE; FROG; HEMATOCRIT; HYPEREMIA; HYPOTENSION; LEUKOCYTE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; RABBIT; SHOCK; SKIN SECRETION; THROMBOCYTE; AMINO ACID SEQUENCE; ANIMAL; BLOOD PRESSURE; DRUG EFFECT; FROGS AND TOADS; GENETICS; HEART RATE; LD 50; LEUKOCYTE COUNT; METABOLISM; MOLECULAR GENETICS; SECRETION; SKIN;

AMPHIBIA; ANURA; BOMBINA MAXIMA; LOTUS; MAMMALIA; MUS; ORYCTOLAGUS CUNICULUS; VERTEBRATA;

AMINO ACID SEQUENCE; ANIMALS; ANURA; BLOOD PRESSURE; CRYSTALLINS; CYTOKINES; FEMALE; HEART RATE; LETHAL DOSE 50; LEUKOCYTE COUNT; MALE; MICE; MOLECULAR SEQUENCE DATA; PEPTIDES; RABBITS; SKIN;

EID: 47849086384     PISSN: 00410101     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxicon.2008.05.007     Document Type: Article

References (43)

1. Almdal T.P., and Vilstrup H. Strict insulin therapy normalises organ nitrogen contents and the capacity of urea nitrogen synthesis in experimental diabetes in rats. Diabetologia 31 (1988) 114-118
2. Audet R., Rioux F., Drapeau G., and Marceau F. Cardiovascular effects of sar-[d-Phe(8)]des-Arg(9)-bradykinin, a metabolically protected agonist of B-1 receptor for kinins, in the anesthetized rabbit pretreated with a sublethal dose of bacterial lipopolysaccharide. J. Pharmacol. Exp. Ther. 280 (1997) 6-15
3. Baus-Loncar M., Kayademir T., Takaishi S., and Wang T. Trefoil factor family 2 deficiency and immune response. Cell. Mol. Life Sci. 62 (2005) 2947-2955
4. Bevins C.L., and Zasloff M. Peptides from frog skin. Annu. Rev. Biochem. 59 (1990) 395-414
5. Bhat S.P. Transparency and non-refractive functions of crystallins - a proposal. Exp. Eye Res. 79 (2004) 809-816
6. Clarke B.T. The natural history of amphibian skin secretions, their normal functioning and potential medical applications. Biol. Rev. Camb. Philos. Soc. 72 (1997) 365-379
7. Correa M.M., Sampaio S.V., Lopes R.A., Mancuso L.C., Cunha O.A.B., Franco J.J., and Giglio J.R. Biochemical and histopathological alterations induced in rats by Tityus serrulatus scorpion venom and its major neurotoxin tityustoxin-I. Toxicon 35 (1997) 1053-1067
8. Daly J.W., Brown G.B., Mensah-Dwumah M., and Myers C.W. Classification of skin alkaloids from neotropical poison-dart frogs (Dendrobatidae). Toxicon 16 (1978) 163-188
9. Daly J.W., Myers C.W., and Whittaker N. Further classification of skin alkaloids from neotropical poison frogs (Dendrobatidae), with a general survey of toxic/noxious substances in the amphibia. Toxicon 25 (1987) 1023-1095
10. Drent M., Cobben N.A.M., Henderson R.F., Wouters E.F.M., and van Dieijen-Visser M. Usefulness of lactate dehydrogenase and its isoenzymes as indicators of lung damage or inflammation. Eur. Respir. J. 9 (1996) 1736-1742
11. Glick Jr. J.H. Serum lactate dehydrogenase isoenzyme and total lactate dehydrogenase values in health and disease, and clinical evaluation of these tests by means of discriminant analysis. Am. J. Clin. Pathol. 52 (1969) 320-328
12. Gomes A., Alam M.I., Auddy B., and Dasgupta S.C. Isolation, purification and partial characterization of a haemolytic protein from Bidder's organ of toad Bufo melanostictus (Schneider). Indian J. Exp. Biol. 32 (1994) 119-123
13. Gomes A., Alam M.I., Muhuri D.C., Auddy B., and Dasgupta S.C. A lethal cardiotoxic protein isolated from Bidder's organ of common Indian toad, Bufo melanostictus Schneider. Indian J. Exp. Biol. 34 (1996) 211-215
14. Hauser F., and Hoffmann W. xP1 and xP4, P-domain peptides expressed in Xenopus laevis stomach mucosa. J. Biol. Chem. 266 (1991) 21306-21309
15. Hauser F., Roeben C., and Hoffmann W. Xp2, a new member of the P-domain peptide family of potential growth-factors, is synthesized in Xenopus laevis skin. J. Biol. Chem. 267 (1992) 14451-14455
16. Hilfiker-Klemer D., Landmesser U., and Drexler H. Molecular mechanisms in heart failure - focus on cardiac hypertrophy, inflammation, angiogenesis, and apoptosis. J. Am. Coll. Cardiol. 48 (2006) A56-A66
17. Hunter S.E.C., Clarke I.N., Kelly D.C., and Titball R.W. Cloning and nucleotide sequencing of the Clostridium perfringens epsilon-toxin gene and its expression in Escherichia coli. Infect. Immun. 60 (1992) 102-110
18. Kelly R.A., and Smith T.W. Cytokines and cardiac contractile function. Circulation 95 (1997) 778-781
19. Lefebvre O., Chenard M.P., Masson R., Linares J., Dierich A., LeMeur M., Wendling C., Tomasetto C., Chambon P., and Rio M.C. Gastric mucosa abnormalities and tumorigenesis in mice lacking the pS2 trefoil protein. Science 274 (1996) 259-262
20. Liu S.B., He Y.Y., Zhang Y., Lee W.H., Qian J.Q., Lai R., and Jin Y. A novel non-lens betagamma-crystallin and trefoil factor complex from amphibian skin and its functional implications. PLoS ONE 3 (2008) e1770
21. Mar A., and Michl H. A study of the high molecular weight hemolysin from the skin secretion of the amphibian Bombina variegata. Toxicon 14 (1976) 191-195
22. 50 determinations of snake venoms using eight to ten experimental animals. Toxicon 24 (1986) 395-401
23. Nelson D.R., and Zusman D.R. Transport and localization of protein S, a spore coat protein, during fruiting body formation by Myxococcus xanthus. J. Bacteriol. 154 (1983) 547-553
24. Ogawa M., Takabatake T., Takahashi T.C., and Takeshima K. Metamorphic change in EP37 expression: members of the betagamma-crystallin superfamily in newt. Dev. Genes Evol. 206 (1997) 417-424
25. Ogawa M., Takahashi T.C., Takabatake T., and Takeshima K. Isolation and characterization of a gene expressed mainly in the gastric epithelium, a novel member of the ep37 family that belongs to the beta gamma-crystallin superfamily. Dev. Growth Differ 40 (1998) 465-473
26. Ownby C.L., Bjarnason J., and Tu A.T. Hemorrhagic toxins from rattlesnake (Crotalus atrox) venom. Pathogenesis of hemorrhage induced by three purified toxins. Am. J. Pathol. 93 (1978) 201-218
27. Pratt D.S., and Kaplan M.M. Primary care: evaluation of abnormal liver-enzyme results in asymptomatic patients. N. Engl. J. Med. 342 (2000) 1266-1271
28. Ray M.E., Wistow G., Su Y.A., Meltzer P.S., and Trent J.M. AIM1, a novel non-lens member of the beta gamma-crystallin superfamily, is associated with the control of tumorigenicity in human malignant melanoma. Proc. Natl. Acad. Sci. U.S.A. 94 (1997) 3229-3234
29. Rio M.C., Bellocq J.P., Daniel J.Y., Tomasetto C., Lathe R., Chenard M.P., Batzenschlager A., and Chambon P. Breast cancer-associated pS2 protein: synthesis and secretion by normal stomach mucosa. Science 241 (1988) 705-708
30. 2+-loaded spherulin 3a from Physarum polycephalum adopts the prototype gamma-crystallin fold in aqueous solution. J. Mol. Biol. 271 (1997) 645-655
31. Sands B.E., and Podolsky D.K. The trefoil peptide family. Annu. Rev. Physiol. 58 (1996) 253-273
32. Sandvig K., and van Deurs B. Entry of ricin and Shiga toxin into cells: molecular mechanisms and medical perspectives. EMBO J. 19 (2000) 5943-5950
33. Sandvig K., and van Deurs B. Delivery into cells: lessons learned from plant and bacterial toxins. Gene Ther. 12 (2005) 865-872
34. Schiavo G., and van der Goot F.G. The bacterial toxin toolkit. Nat. Rev. Mol. Cell Biol. 2 (2001) 530-537
35. Sherman K.E. Alanine aminotransferase in clinical-practice, a review. Arch. Intern. Med 151 (1991) 260-265
36. Takabatake T., Takahashi T.C., and Takeshima K. Cloning of an epidermis-specific Cynops cDNA from neurula library. Dev. Growth Differ. 34 (1992) 277-283
37. Taupin D., and Podolsky D.K. Trefoil factors: initiators of mucosal healing. Nat. Rev. Mol. Cell. Biol. 4 (2003) 721-734
38. Teichmann U., Ray M.E., Ellison J., Graham C., Wistow G., Meltzer P.S., Trent J.M., and Pavan W.J. Cloning and tissue expression of the mouse ortholog of AIM1, a beta gamma-crystallin superfamily member. Mamm. Genome 9 (1998) 715-720
39. Thim L. Trefoil peptides: from structure to function. Cell. Mol. Life Sci. 53 (1997) 888-903
40. Thim L., and May F.E.B. Structure of mammalian trefoil factors and functional insights. Cell. Mol. Life Sci. 62 (2005) 2956-2973
41. Wistow G., Jaworski C., and Rao P.V. A non-lens member of the beta gamma-crystallin superfamily in a vertebrate, the amphibian Cynops. Exp. Eye Res. 61 (1995) 637-639
42. Wistow G.J., and Piatigorsky J. Lens crystallins: the evolution and expression of proteins for a highly specialized tissue. Annu. Rev. Biochem. 57 (1988) 479-504
43. Zhang J., Zhang Y., Wan S.G., Wei S.S., Lee W.H., and Zhang Y. Bm-TFF2, a trefoil factor protein with platelet activation activity from frog Bombina maxima skin secretions. Biochem. Biophys. Res. Commun. 330 (2005) 1027-1033