Cardiovascular effects of Sar-[D-Phe8]des-Arg9-bradykinin, a metabolically protected agonist of B1 receptor for kinins, in the anesthetized rabbit pretreated with a sublethal dose of bacterial lipopolysaccharide

Journal of Pharmacology and Experimental Therapeutics

Volumn 280, Issue 1, 1997, Pages 6-15

  Audet, Ritchie ^a   Rioux, Francis ^a   Drapeau, Guy ^a   Marceau, François ^a  

^a LAVAL UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

3 [3 TERT BUTYLTHIO 1 (4 CHLOROBENZYL) 5 ISOPROPYL 2 INDOLYL] 2,2 DIMETHYLPROPIONIC ACID; 6 (2 CHLOROPHENYL) 9 [(3,4 DIMETHOXYPHENYL)THIOMETHYLTHIOCARBONYL] 4,7,8,10 TETRAHYDRO 1 METHYLPYRIDO[4',3':4,5]THIENO[3,2 F][1,2,4]TRIAZOLO[4,3 A][1,4]DIAZEPINE; ATROPINE; BACTERIUM LIPOPOLYSACCHARIDE; BRADYKININ B1 RECEPTOR AGONIST; BRADYKININ DERIVATIVE; DAZMEGREL; DICLOFENAC; GLIBENCLAMIDE; HEXAMETHONIUM; INDOMETACIN; N(G) NITROARGININE; PROPRANOLOL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIHYPERTENSIVE ACTIVITY; ARTICLE; CARDIOVASCULAR EFFECT; CONTROLLED STUDY; DRUG ANTAGONISM; DRUG CLEARANCE; DRUG EFFECT; DRUG ELIMINATION; DRUG HALF LIFE; DRUG MECHANISM; FEMALE; HEART OUTPUT; HEMODYNAMICS; INTRAARTERIAL DRUG ADMINISTRATION; MALE; NONHUMAN; PRIORITY JOURNAL; RABBIT; VASODILATATION;

ANESTHESIA; ANIMALS; BRADYKININ; FEMALE; HALOTHANE; HEMODYNAMIC PROCESSES; LIPOPOLYSACCHARIDES; MALE; NITRIC OXIDE; RABBITS; RECEPTOR, BRADYKININ B1; RECEPTORS, BRADYKININ;

EID: 0030899954     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (36)

1. 9-bradykinin in vitro in vivo. Br. J. Pharmacol. 92: 257-264, 1987.
2. 1 receptors. Eur. J. Pharmacol. 130: 11-18, 1986.
3. 1 receptors in vivo in a model of persistent inflammatory mechanical hyperalgesia in the rat. Neuropharmacology 33: 127-133, 1994a.
4. 2 receptor mechanisms in cytokine-induced mechanical hyperalgesia in the rat, Br. J. Pharmacol. 113: 63-68, 1994b.
5. 9-bradykinin to relax rabbit isolated mesenteric arteries is acquired during in vitro incubation. Eur. J. Pharmacol. 142: 141-144, 1987.
6. 9-bradykinin: Possible roles of interleukin-1. Br. J. Pharmacol. 103: 1057-1066, 1991.
7. 1 receptor-mediated responses in the pulmonary vascular bed. Circ. Res. 75: 1064-1072, 1994.
8. DRAPEAU, G. AND REGOLI, D.: Synthesis of bradykinin analogs. Methods Enzymol. 163: 263-272, 1988.
9. 1 receptors for kinins. J. Pharmacol. Exp. Ther. 259: 997-1003, 1991.
10. 1 receptors for kinins. J. Pharmacol. Exp. Ther. 266: 192-199, 1993.
11. + channels. Annu. Rev. Pharmacol. Toxicol. 33: 597-637, 1993.
12. 2 production. Br. J. Pharmacol. 113: 389-394, 1994.
13. GILLARD, J., FORD-HUTCHINSON, A. W., CHAN, C., CHARLESON, S., DENIS, D., FOSTER, A., FORTIN, R., LEGER, S., MCFARLANE, C. S., MORTON, H., PIECHUTA, H., RIENDEAU, D., ROUZER, C. A., ROKACH, J., YOUNG, R., MACINTYRE, D. E., PETERSON, L., BACH, T., EIERMANN, G., HOPPLE, S., HUMES, J., HUPE, L., LUELL, S., METZGER, J., MEURER, R., MILLER, D. K., OPAS, E. AND PACHOLOK, S.: L-663,536 (MK-886) (3-[1-(4-chlorobenzyl)-3-t-butyl-thio-5-isopropylindol-2-yl]-2,2 dimethylpropanoic acid), a novel, orally active leukotriene biosynthesis inhibitor. Can. J. Physiol. Phurmacol. 67: 456-464, 1989.
14. 1 receptors and development of a cellular model for the investigation of these receptors, Br. J. Pharmacol. 109: 1254-1262, 1993.
15. 1 receptors for kinins. Immunopharmacology 29: 141-147, 1994.
16. 2-kinin receptors in the renal tubular and hemodynamic response to bradykinin. Am. J. Physiol. 262: R72-R76, 1992.
17. LUNDBERG, C., MARCEAU, F. AND HUGLI, T. E.: C5a-induced hemodynamic and hematologic changes in the rabbit. Role of cyclooxygenase products and polymorphonuclear leucocytes. Am. J. Pathol. 128: 471-483, 1987.
18. 1 receptors: A review. Immunopharmacology 30: 1-26, 1995.
19. 1 bradykinin receptor. J. Biol. Chem. 269: 21583-21586, 1994.
20. G-nitro-arginine (L-NOARG) a novel, L-arginine-reversible inhibitor of endothelium-dependent vasodilatation in vitro. Br. J. Pharmacol. 99: 408-412, 1990.
21. 2 receptors of vasodepressor responses to intravenously administered kinins in anaesthetized dogs. Br. J. Pharmacol. 110: 71-76, 1993.
22. PARRY, M. J., RANDALL, M. J., HAWKESWOOD, E., CROSS, P. E. AND DICKINSON, R. P.: Enhanced production of prostacyclin in blood after treatment with selective thromboxane synthetase inhibitor, UK-38,485. Br. J. Pharmacol. 77: 547P, 1982.
23. 1 receptor-mediated relaxation in the isolated rabbit carotid artery. Eur. J. Pharmacol. 239: 63-67, 1993.
24. 9-bradykinin using a chemiluminoscence enzyme immunoassay: application to its kinietic profile during plasma activation. J. Immunol. Methods 180: 247-257, 1995.
25. REES, D. D., PALMER, R. M. J. AND MONCADA, S.: Role of endothelium-derived nitric oxide in the regulation of blood pressure. Proc. Natl. Acad. Sci. U.S.A. 86: 3375-3378, 1989.
26. REES, D. D., PALMER, R. M. J., SCHULTZ, R., HODSON, H. F. AND MONCADA, S.: Characterization of three inhibitors of endothelial nitric oxide synthase in vitro and in vivo. Br. J. Pharmacol. 101: 746-752, 1990.
27. 1-receptors for kinins in the rabbit by a bacterial lipopolysaccharide. Eur. J. Pharmacol. 71: 105-115, 1981.
28. RITTER, J. M., DOKTOR, H. S. AND CRAGOE JR, E. J.: Actions of bradykinin and related peptides on rabbit coeliac artery rings. Br. J. Pharmacol. 96: 23-28, 1989.
29. ROWLAND, M. AND TOZER, T. N.: Clinical Pharmacokinotics: Concept and Applications, 2nd ed., pp. 17-32, Lea and Febiger, Philadelphia, 1989.
30. RUSHMER, R. F.: Systemic arterial pressure. In Structure and Function of the Cardiovascular System, 2nd ed., pp. 176-216, W. B. Saundors, Philadelphia, 1976.
31. 1 receptors in rabbit aorta smooth muscle cells in culture. Eur. J. Pharmacol. 266: 277-282, 1994.
32. 9-bradykinin increases during E. coli septicemia in the pig. Adv. Exp. Med. Biol. 247B: 389-393, 1989.
33. 9-bradykinin in young Brown Norway rats pretrcated with endotoxin. Eur. J. Pharmacol. 274: 225-228, 1995.
34. 1 receptorinduced plasma extravasation following persistent local inflammation in rat: An examination of neurogenic and sympathetic components: Br. J. Pharmacol. 113: 27P, 1994.
35. WHITTLE, B. J. R., LOPEZ-DELMONTE, J. AND REES, D. D.: Modulation of the vasode-pressor actions of acetylcholine, bradykinin, substance P and endothelin in the rat by a specific inhibitor of nitric oxide formation. Br. J. Pharmacol, 98: 646-652, 1989.
36. YUE, T. L., RABINOVICI, R., FARHAT, M. AND FEUERSTEIN, G.: Pharmacologic profile of BN50739, a new PAF antagonist in vitro and in vivo. Prostaglandins 39: 469-480, 1990.