Aldose reductase regulates hepatic peroxisome proliferator-activated receptor α phosphorylation and activity to impact lipid homeostasis

Journal of Biological Chemistry

Volumn 283, Issue 25, 2008, Pages 17175-17183

  Qiu, Longxin ^a,c   Wu, Xiaochun ^b   Chau, Jenny F L ^b   Szeto, Irene Y Y ^b   Wing, Yip Tam ^b   Guo, Zongsheng ^a   Chung, Sookja K ^b   Oates, Peter J ^d,e   Chung, Stephen S M ^a,b   Yang, James Y ^a,b  

^a XIAMEN UNIVERSITY   (China)

^b UNIVERSITY OF HONG KONG   (Hong Kong)

^c LONGYAN UNIVERSITY   (China)

^d PFIZER GLOBAL RESEARCH AND DEVELOPMENT   (United States)

^e PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOLOGY; FATTY ACIDS; MAMMALS; PHYSIOLOGY;

CARNITINE PALMITOYLTRANSFERASE; DEPHOSPHORYLATIONS; GENETIC DEFICIENCIES; LIPID METABOLISMS; NONESTERIFIED FATTY ACIDS; PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR; PHOSPHOINOSITIDE 3-KINASE; SUBSTANTIAL REDUCTION;

PHOSPHORYLATION;

ACETYL COENZYME A OXIDASE; ALDEHYDE REDUCTASE; APOLIPOPROTEIN C3; CARNITINE PALMITOYLTRANSFERASE I; FATTY ACID; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; OXIDOREDUCTASE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; TRIACYLGLYCEROL; UNCLASSIFIED DRUG; LIPID; MITOGEN ACTIVATED PROTEIN KINASE KINASE 4; MITOGEN ACTIVATED PROTEIN KINASE P38; PHOSPHATIDYLINOSITOL 3 KINASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; FATTY ACID BLOOD LEVEL; HOMEOSTASIS; LIPID METABOLISM; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEPHOSPHORYLATION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; STREPTOZOCIN DIABETES; TRIACYLGLYCEROL BLOOD LEVEL; ANIMAL; CHEMISTRY; GENE EXPRESSION REGULATION; LIVER; METABOLISM; PHOSPHORYLATION; SIGNAL TRANSDUCTION;

MUS;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ALDEHYDE REDUCTASE; ANIMALS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HOMEOSTASIS; LIPIDS; LIVER; MAP KINASE KINASE 4; MICE; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PPAR ALPHA; SIGNAL TRANSDUCTION;

EID: 47749155983     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M801791200     Document Type: Article

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