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Volumn 7, Issue 13, 2008, Pages 1962-1972

CDK redundancy guarantees cell cycle progression in Rb-negative tumor cells independently of their p16 status

Author keywords

cdk1; cdk2; cdk3; ink4a; p107; p130; p16; Rb

Indexed keywords

CYCLIN D; CYCLIN DEPENDENT KINASE; CYCLIN DEPENDENT KINASE 2; CYCLIN DEPENDENT KINASE 3; CYCLIN DEPENDENT KINASE 4; PROTEIN P16; PROTEIN P27; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR E2F;

EID: 47749151475     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.4161/cc.7.13.6071     Document Type: Article
Times cited : (10)

References (48)
  • 1
    • 0029119740 scopus 로고
    • Cell cycle control in mammalian cells: Role of cyclins, cyclin dependent kinases (CDKs), growth suppressor genes and cyclin-dependent kinase inhibitors (CKIs)
    • Grana X, Reddy EP. Cell cycle control in mammalian cells: role of cyclins, cyclin dependent kinases (CDKs), growth suppressor genes and cyclin-dependent kinase inhibitors (CKIs). Oncogene 1995; 11:211-9.
    • (1995) Oncogene , vol.11 , pp. 211-219
    • Grana, X.1    Reddy, E.P.2
  • 2
    • 0029033861 scopus 로고
    • The retinoblastoma protein and cell cycle control
    • Weinberg RA. The retinoblastoma protein and cell cycle control. Cell 1995; 81:323-30.
    • (1995) Cell , vol.81 , pp. 323-330
    • Weinberg, R.A.1
  • 3
    • 0035095973 scopus 로고    scopus 로고
    • Regulation of the retinoblastoma tumor suppressor protein by cyclin/cdks
    • Adams PD. Regulation of the retinoblastoma tumor suppressor protein by cyclin/cdks. Biochim Biophys Acta 2001; 1471:123-33.
    • (2001) Biochim Biophys Acta , vol.1471 , pp. 123-133
    • Adams, P.D.1
  • 4
    • 0032437776 scopus 로고    scopus 로고
    • Role of the retinoblastoma protein family, pRB, p107 and p130 in the negative control of cell growth
    • Grana X, Garriga J, Mayol X. Role of the retinoblastoma protein family, pRB, p107 and p130 in the negative control of cell growth. Oncogene 1998; 17:3365-83.
    • (1998) Oncogene , vol.17 , pp. 3365-3383
    • Grana, X.1    Garriga, J.2    Mayol, X.3
  • 5
    • 0037184608 scopus 로고    scopus 로고
    • 1 cyclin/cyclin-dependent kinase-coordinated phosphorylation of endogenous pocket proteins differentially regulates their interactions with E2F4 and E2F1 and gene expression
    • 1 cyclin/cyclin-dependent kinase-coordinated phosphorylation of endogenous pocket proteins differentially regulates their interactions with E2F4 and E2F1 and gene expression. J Biol Chem 2002; 277:50263-74.
    • (2002) J Biol Chem , vol.277 , pp. 50263-50274
    • Calbo, J.1    Parreno, M.2    Sotillo, E.3    Yong, T.4    Mazo, A.5    Garriga, J.6    Grana, X.7
  • 8
    • 33749503799 scopus 로고    scopus 로고
    • Combined depletion of cell cycle and transcriptional cyclin-dependent kinase activities induces apoptosis in cancer cells
    • Cai D, Latham VM Jr, Zhang X, Shapiro GI. Combined depletion of cell cycle and transcriptional cyclin-dependent kinase activities induces apoptosis in cancer cells. Cancer Res 2006; 66:9270-80.
    • (2006) Cancer Res , vol.66 , pp. 9270-9280
    • Cai, D.1    Latham Jr, V.M.2    Zhang, X.3    Shapiro, G.I.4
  • 9
    • 0642378446 scopus 로고    scopus 로고
    • Cell cycle deregulation: A common motif in cancer
    • Malumbres M, Carnero A. Cell cycle deregulation: a common motif in cancer. Prog Cell Cycle Res 2003; 5:5-18.
    • (2003) Prog Cell Cycle Res , vol.5 , pp. 5-18
    • Malumbres, M.1    Carnero, A.2
  • 14
    • 0142258073 scopus 로고    scopus 로고
    • The tumor-suppressive functions of the human INK4A locus
    • Voorhoeve PM, Agami R. The tumor-suppressive functions of the human INK4A locus. Cancer Cell 2003; 4:311-9.
    • (2003) Cancer Cell , vol.4 , pp. 311-319
    • Voorhoeve, P.M.1    Agami, R.2
  • 15
    • 0027769876 scopus 로고
    • A new regulatory motif in cell cycle control causing specific inhibition of cyclin D/CDK4
    • Serrano M, Hannon GJ, Beach D. A new regulatory motif in cell cycle control causing specific inhibition of cyclin D/CDK4. Nature 1993; 366:704-7.
    • (1993) Nature , vol.366 , pp. 704-707
    • Serrano, M.1    Hannon, G.J.2    Beach, D.3
  • 16
    • 0031842101 scopus 로고    scopus 로고
    • Requirement of cyclin E-Cdk2 inhibition in p16(INK4a)-mediated growth suppression
    • Jiang H, Chou HS, Zhu L. Requirement of cyclin E-Cdk2 inhibition in p16(INK4a)-mediated growth suppression. Mol Cell Biol 1998; 18:5284-90.
    • (1998) Mol Cell Biol , vol.18 , pp. 5284-5290
    • Jiang, H.1    Chou, H.S.2    Zhu, L.3
  • 17
    • 0346873027 scopus 로고    scopus 로고
    • Loss of retinoblastoma but not p16 function allows bypass of replicative senescence in human fibroblasts
    • Wei W, Herbig U, Wei S, Dutriaux A, Sedivy JM. Loss of retinoblastoma but not p16 function allows bypass of replicative senescence in human fibroblasts. EMBO Rep 2003; 4:1061-6.
    • (2003) EMBO Rep , vol.4 , pp. 1061-1066
    • Wei, W.1    Herbig, U.2    Wei, S.3    Dutriaux, A.4    Sedivy, J.M.5
  • 24
    • 0033575920 scopus 로고    scopus 로고
    • Deregulated cyclin E induces chromosome instability
    • Spruck CH, Won KA, Reed SI. Deregulated cyclin E induces chromosome instability. Nature 1999; 401:297-300.
    • (1999) Nature , vol.401 , pp. 297-300
    • Spruck, C.H.1    Won, K.A.2    Reed, S.I.3
  • 28
    • 0041327168 scopus 로고    scopus 로고
    • Proliferation of cancer cells despite CDK2 inhibition
    • Tetsu O, McCormick F. Proliferation of cancer cells despite CDK2 inhibition. Cancer Cell 2003; 3:233-45.
    • (2003) Cancer Cell , vol.3 , pp. 233-245
    • Tetsu, O.1    McCormick, F.2
  • 29
    • 0027229136 scopus 로고
    • Functional interactions of the retinoblastoma protein with mammalian D- type cyclins
    • Ewen ME, Sluss HK, Sherr CJ, Matsushime H, Kato J, Livingston DM. Functional interactions of the retinoblastoma protein with mammalian D- type cyclins. Cell 1993; 73:487-97.
    • (1993) Cell , vol.73 , pp. 487-497
    • Ewen, M.E.1    Sluss, H.K.2    Sherr, C.J.3    Matsushime, H.4    Kato, J.5    Livingston, D.M.6
  • 30
    • 0030916209 scopus 로고    scopus 로고
    • Inhibition of cyclin D1 phosphorylation on threonine-286 prevents its rapid degradation via the ubiquitin-proteasome pathway
    • Diehl JA, Zindy F, Sherr CJ. Inhibition of cyclin D1 phosphorylation on threonine-286 prevents its rapid degradation via the ubiquitin-proteasome pathway. Genes Dev 1997; 11:957-72.
    • (1997) Genes Dev , vol.11 , pp. 957-972
    • Diehl, J.A.1    Zindy, F.2    Sherr, C.J.3
  • 31
    • 0035852699 scopus 로고    scopus 로고
    • A premature-termination mutation in the Mus musculus cyclin-dependent kinase 3 gene
    • Ye X, Zhu C, Harper J W. A premature-termination mutation in the Mus musculus cyclin-dependent kinase 3 gene. Proc Natl Acad Sci USA 2001; 98:1682-6.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 1682-1686
    • Ye, X.1    Zhu, C.2    Harper, J.W.3
  • 35
    • 0035063183 scopus 로고    scopus 로고
    • The Rb/E2F pathway and cancer
    • Nevins JR. The Rb/E2F pathway and cancer. Hum Mol Genet 2001; 10:699-703.
    • (2001) Hum Mol Genet , vol.10 , pp. 699-703
    • Nevins, J.R.1
  • 37
    • 0038392934 scopus 로고    scopus 로고
    • Increased ezrin expression and activation by CDK5 coincident with acquisition of the senescent phenotype
    • Yang HS, Hinds P W. Increased ezrin expression and activation by CDK5 coincident with acquisition of the senescent phenotype. Mol Cell 2003; 11:1163-76.
    • (2003) Mol Cell , vol.11 , pp. 1163-1176
    • Yang, H.S.1    Hinds, P.W.2
  • 38
    • 29244468847 scopus 로고    scopus 로고
    • Secrets of a double agent: CDK7 in cell cycle control and transcription
    • Fisher R P. Secrets of a double agent: CDK7 in cell cycle control and transcription. J Cell Sci 2005; 118:5171-80.
    • (2005) J Cell Sci , vol.118 , pp. 5171-5180
    • Fisher, R.P.1
  • 39
    • 0037686707 scopus 로고    scopus 로고
    • Reversal of senescence in mouse fibroblasts through lentiviral suppression of p53
    • Dirac AM, Bernards R. Reversal of senescence in mouse fibroblasts through lentiviral suppression of p53. J Biol Chem 2003; 278:11731-4.
    • (2003) J Biol Chem , vol.278 , pp. 11731-11734
    • Dirac, A.M.1    Bernards, R.2
  • 40
    • 0031930466 scopus 로고    scopus 로고
    • Stable binding to E2F is not required for the retinoblastoma protein to activate transcription, promote differentiation, and suppress tumor cell growth
    • Sellers WR, Novitch BG, Miyake S, Heith A, Otterson GA, Kaye FJ, Lassar AB, Kaelin WGJ. Stable binding to E2F is not required for the retinoblastoma protein to activate transcription, promote differentiation, and suppress tumor cell growth. Genes Dev 1998; 12:95-106.
    • (1998) Genes Dev , vol.12 , pp. 95-106
    • Sellers, W.R.1    Novitch, B.G.2    Miyake, S.3    Heith, A.4    Otterson, G.A.5    Kaye, F.J.6    Lassar, A.B.7    Kaelin, W.G.J.8
  • 41
    • 0027742184 scopus 로고
    • Distinct roles for cyclin-dependent kinases in cell cycle control
    • van den HS, Harlow E. Distinct roles for cyclin-dependent kinases in cell cycle control. Science 1993; 262:2050-4.
    • (1993) Science , vol.262 , pp. 2050-2054
    • van den, H.S.1    Harlow, E.2
  • 42
    • 0032984610 scopus 로고    scopus 로고
    • Activation of the murine dihydrofolate reductase promoter by E2F1. A requirement for CBP recruitment
    • Fry CJ, Pearson A, Malinowski E, Bartley SM, Greenblatt J, Farnham PJ. Activation of the murine dihydrofolate reductase promoter by E2F1. A requirement for CBP recruitment. J Biol Chem 1999; 274:15883-91.
    • (1999) J Biol Chem , vol.274 , pp. 15883-15891
    • Fry, C.J.1    Pearson, A.2    Malinowski, E.3    Bartley, S.M.4    Greenblatt, J.5    Farnham, P.J.6
  • 45
    • 33847661809 scopus 로고    scopus 로고
    • Protocol for the fast chromatin immunoprecipitation (ChIP) method
    • Nelson JD, Denisenko O, Bomsztyk K. Protocol for the fast chromatin immunoprecipitation (ChIP) method. Nat Protoc 2006; 1:179-85.
    • (2006) Nat Protoc , vol.1 , pp. 179-185
    • Nelson, J.D.1    Denisenko, O.2    Bomsztyk, K.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.