The relationship between single-channel and whole-cell conductance in the T-type Ca2+ channel Cav3.1

Biophysical Journal

Volumn 95, Issue 2, 2008, Pages 931-941

  Bittner, Katie C ^a   Hanck, Dorothy A ^a  

^a UNIVERSITY OF CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CA(V)3.1 PROTEIN, MOUSE; CALCIUM CHANNEL T TYPE;

ARTICLE; CELL MEMBRANE; CELL MEMBRANE POTENTIAL; CHANNEL GATING; CHEMISTRY; ELECTRIC CONDUCTIVITY; PHYSIOLOGY;

CALCIUM CHANNELS, T-TYPE; CELL MEMBRANE; ELECTRIC CONDUCTIVITY; ION CHANNEL GATING; MEMBRANE POTENTIALS;

EID: 47749138871     PISSN: 00063495     EISSN: 15420086     Source Type: Journal    
DOI: 10.1529/biophysj.107.128124     Document Type: Article

References (36)

1. Carbone, E., and H. D. Lux. 1987. Single low-voltage-activated calcium channels in chick and rat sensory neurones. J. Physiol. 386:571-601.
2. Fox, A. P., M. C. Nowycky, and R. W. Tsien. 1987. Single-channel recordings of three types of calcium channels in chick sensory neurones. J. Physiol. 394:173-200.
3. Perez-Reyes, E. 2003. Molecular physiology of low-voltage-activated t-type calcium channels. Physiol. Rev. 83:117-161.
4. Wolfart, J., and J. Roeper. 2002. Selective coupling of T-type calcium channels to SK potassium channels prevents intrinsic bursting in dopaminergic midbrain neurons. J. Neurosci. 22:3404-3413.
5. Mangoni, M. E., A. Traboulsie, A. L. Leoni, B. Couette, L. Marger, K. Le Quang, E. Kupfer, A. Cohen-Solal, J. Vilar, H. S. Shin, D. Escande, F. Charpentier, J. Nargeot, and P. Lory. 2006. Bradycardia and slowing of the atrioventricular conduction in mice lacking CaV3.1/α1G T-type calcium channels. Circ. Res. 98:1422-1430.
6. 2+ channels. Neuron. 31:35-45.
7. 2+ channel plays a crucial role in stabilizing sleep. Proc. Natl. Acad. Sci. USA. 102:1743-1748.
8. 2+ window current. Circ. Res. 70:456-464.
9. Droogmans, G., and B. Nilius. 1989. Kinetic properties of the cardiac T-type calcium channel in the guinea-pig. J. Physiol. 419:627-650.
10. Barrett, P. Q., H. K. Lu, R. Colbran, A. Czernik, and J. J. Pancrazio. 2000. Stimulation of unitary T-type Ca(2+) channel currents by calmodulin-dependent protein kinase II. Am. J. Physiol. Cell Physiol. 279:C1694-C1703.
11. Shuba, Y. M., V. I. Teslenko, A. N. Savchenko, and N. H. Pogorelaya. 1991. The effect of permeant ions on single calcium channel activation in mouse neuroblastoma cells: ion-channel interaction. J. Physiol. 443:25-44.
12. 2+ selectivity of α1G T-type calcium channels. Biophys. J. 79:3052-3062.
13. 2+ channels. Biochim. Biophys. Acta. 1768:1406-1419.
14. Fukushima, Y., and S. Hagiwara. 1985. Currents carried by monovalent cations through calcium channels in mouse neoplastic B lymphocytes. J. Physiol. 358:255-284.
15. Carbone, E., and H. D. Lux. 1987. Kinetics and selectivity of a low-voltage-activated calcium current in chick and rat sensory neurones. J. Physiol. 386:547-570.
16. McRory, J. E., C. M. Santi, K. S. Hamming, J. Mezeyova, K. G. Sutton, D. L. Baillie, A. Stea, and T. P. Snutch. 2001. Molecular and functional characterization of a family of rat brain T-type calcium channels. J. Biol. Chem. 276:3999-4011.
17. 2+ channels. J. Gen. Physiol. 130:415-425.
18. v3.1 variants from the human T-type calcium channel gene CACNA1G: alternative structures, developmental expression, and biophysical variations. Proteins. 64:320-342.
19. Qin, F., A. Auerbach, and F. Sachs. 1996. Estimating single-channel kinetic parameters from idealized patch-clamp data containing missed events. Biophys. J. 70:264-280.
20. Qin, F. 2004. Restoration of single-channel currents using the segmental k-means method based on hidden Markov modeling. Biophys. J. 86:1488-1501.
21. Monteil, A., J. Chemin, E. Bourinet, G. Mennessier, P. Lory, and J. Nargeot. 2000. Molecular and functional properties of the human α(1G) subunit that forms T-type calcium channels. J. Biol. Chem. 275:6090-6100.
22. 2+ channel α(1G). J. Biol. Chem. 276:45628-45635.
23. Klugbauer, N., E. Marais, L. Lacinova, and F. Hofmann. 1999. A T-type calcium channel from mouse brain. Pflugers Arch. 437:710-715.
24. Lee, J. H., A. N. Daud, L. L. Cribbs, A. E. Lacerda, A. Pereverzev, U. Klockner, T. Schneider, and E. Perez-Reyes. 1999. Cloning and expression of a novel member of the low voltage-activated T-type calcium channel family. J. Neurosci. 19:1912-1921.
25. Perez-Reyes, E., L. L. Cribbs, A. Daud, A. E. Lacerda, J. Barclay, M. P. Williamson, M. Fox, M. Rees, and J. H. Lee. 1998. Molecular characterization of a neuronal low-voltage-activated T-type calcium channel. Nature. 391:896-900.
26. 2+ channel gene family. Circ. Res. 83:103-109.
27. Guia, A., M. D. Stern, E. G. Lakatta, and I. R. Josephson. 2001. Ion concentration-dependence of rat cardiac unitary L-type calcium channel conductance. Biophys. J. 80:2742-2750.
28. Church, P. J., and E. F. Stanley. 1996. Single L-type calcium channel conductance with physiological levels of calcium in chick ciliary ganglion neurons. J. Physiol. 496:59-68.
29. Talley, E. M., L. L. Cribbs, J. H. Lee, A. Daud, E. Perez-Reyes, and D. A. Bayliss. 1999. Differential distribution of three members of a gene family encoding low voltage-activated (T-type) calcium channels. J. Neurosci. 19:1895-1911.
30. Williams, M. E., M. S. Washburn, M. Hans, A. Urrutia, P. F. Brust, P. Prodanovich, M. M. Harpold, and K. A. Stauderman. 1999. Structure and functional characterization of a novel human low-voltage activated calcium channel. J. Neurochem. 72:791-799.
31. 2+. J. Physiol. 430:159-188.
32. Kostyuk, P. G., M. Shuba Ya, and A. N. Savchenko. 1988. Three types of calcium channels in the membrane of mouse sensory neurons. Pflugers Arch. 411:661-669.
33. 2+ channel α1G (CaV3.1). J. Gen. Physiol. 121:511-528.
34. Delisle, B. P., and J. Satin. 2003. Monovalent cations contribute to T-type calcium channel (Cav3.1 and Cav3.2) selectivity. J. Membr. Biol. 193:185-194.
35. v1.2 calcium channel reduce barium currents without affecting calcium currents. Biophys. J. 89:1731-1743.
36. Kostyuk, P. G., S. L. Mironov, and Y. M. Shuba. 1983. Two ion-selecting filters in the calcium channel in mouse neoplastic B lymphocytes. J. Membr. Biol. 76:83-93.