Molecular determinant for specific Ca/Ba selectivity profiles of low and high threshold Ca2+ channels

Journal of General Physiology

Volumn 130, Issue 4, 2007, Pages 415-425

  Cens, Thierry ^a,b   Rousset, Matthieu ^a,b   Kajava, Andrey ^a,b   Charnet, Pierre ^a,b  

^a CNRS   (France)

^b UNIV MONTPELLIER   (France)

Author keywords

[No Author keywords available]

Indexed keywords

BARIUM ION; CALCIUM CHANNEL; CALCIUM ION; CATION; VOLTAGE GATED CALCIUM CHANNEL;

ANIMAL CELL; ARTICLE; BINDING SITE; BRAIN; CALCIUM TRANSPORT; CHANNEL GATING; GENE MUTATION; ION TRANSPORT; MATHEMATICAL MODEL; MOLECULAR MODEL; NONHUMAN; NUCLEOTIDE SEQUENCE; OOCYTE; POLYMERASE CHAIN REACTION; XENOPUS LAEVIS;

ANIMALS; BARIUM; BINDING SITES; CALCIUM; CALCIUM CHANNEL BLOCKERS; CALCIUM CHANNELS; CATIONS, DIVALENT; COMPUTER SIMULATION; ION CHANNEL GATING; ION TRANSPORT; KINETICS; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; OOCYTES; PATCH-CLAMP TECHNIQUES; RATS;

EID: 34748887977     PISSN: 00221295     EISSN: 00221295     Source Type: Journal    
DOI: 10.1085/jgp.200709771     Document Type: Article

References (46)

1. Almers, W., E.W. McCleskey, and P.T. Palade. 1984. A non-selective cation conductance in frog muscle membrane blocked by micromolar external calcium ions. J. Physiol. 353:565-583.
2. Begenisich, T.B., and M.D. Cahalan. 1980. Sodium channel permeation in squid axons. I: Reversal potential experiments. J. Physiol. 307:217-242.
3. Bourinet, E., Zamponi, G.W., Stea, A., Soong, T.W., Lewis, B.A., Jones, L.P., Yue, D.T., and Snutch, T.P. 1996. The α1E calcium channel exhibits permeation properties similar to low-voltage-activated calcium channels. J. Neurosci. 16:4983-4993.
4. Campbell, D.L., R.L. Rasmusson, and H.C. Strauss. 1988. Theoretical study of the voltage and concentration dependence of the anomalous mole fraction effect in single calcium channels. New insights into the characterization of multi-ion channels. Biophys. J. 54:945-954.
5. 2+ channels. Annu. Rev. Cell Dev. Biol. 16:521-555.
6. 2+ entering from the intracellular pore entrance. J. Gen. Physiol. 116:349-362.
7. 2+ channels by the concerted action of S5-6 regions. Biophys. J. 84:1709-1719.
8. 2+ channel. J. Gen. Physiol. 116:569-586.
9. 2+ channel gene family. Circ. Res. 83:103-109.
10. + channels by TEA: results from molecular dynamics simulations of the KcsA channel. J. Gen. Physiol. 118:207-218.
11. Dang, T.X., and E.W. McCleskey. 1998. Ion channel selectivity through stepwise changes in binding affinity. J. Gen. Physiol. 111:185-193.
12. Dayring, H.E., A. Tramonato, S.R. Sprang, and R.J. Fletterick. 1986. Interactive program for visualization and modeling of proteins, nucleic acids and small molecules. J. Mol. Graph. 4:82-87.
13. + conduction and selectivity. Science. 280:69-77.
14. Efimov, A.V. 1993. Standard structures in proteins. Prog. Biophys. Mol. Biol. 60:201-239.
15. 2+ interactions. Neuron. 15:1121-1132.
16. Feng, Z.P., J. Hamid, C. Doering, S.E. Jarvis, G.M. Bosey, E. Bourinet, T.P. Snutch, and G.W. Zamponi. 2001. Amino acid residues outside of the pore region contribute to N-type calcium channel permeation. J. Biol. Chem. 276:5726-5730.
17. Heinemann, S.H., H. Terlau, W. Stuhmer, K. Imoto, and S. Numa. 1992. Calcium channel characteristics conferred on the sodium channel by single mutations. Nature. 356:441-443.
18. Hess, P., and R.W. Tsien. 1984. Mechanism of ion permeation through calcium channels. Nature. 309:453-456.
19. Higgins, D.G., J.D. Thompson, and T.J. Gibson. 1996. Using CLUSTAL for multiple sequence alignments. Methods Enzymol. 266:383-402.
20. Hille, B. 2001. Ion channels of Excitable Membranes. Third edition. Sinauer Associates Inc., Sunderland, MA. 814 pp.
21. Isom, L.L., K.S. De Jongh, and W.A. Catterall. 1994. Auxiliary subunits of voltage-gated ion channels. Neuron. 12:1183-1194.
22. + channel. Nature. 423:33-41.
23. Kim, M.S., T. Morii, L.X. Sun, K. Imoto, and Y. Mori. 1993. Structural determinants of ion selectivity in brain calcium channel. FEBS Lett. 318:145-148.
24. 2+ channel pore in rat phaeochromocytoma cells. J. Physiol. 466:657-682.
25. 2+ channel in rat phaeochromocytoma cells: two sets of ion binding sites in the pore. J. Physiol. 466:629-655.
26. Kurata, Y., R. Sato, I. Hisatome, and S. Imanishi. 1999. Mechanisms of cation permeation in cardiac sodium channel: description by dynamic pore model. Biophys. J. 77:1885-1904.
27. Lee, J.H., A.N. Daud, L.L. Cribbs, A.E. Lacerda, A. Pereverzev, U. Klockner, T. Schneider, and E. Perez-Reyes. 1999. Cloning and expression of a novel member of the low voltage-activated T- type calcium channel family. J. Neurosci. 19:1912-1921.
28. 2+ channel. Biochemistry. 40:6786-6794.
29. + channels. Science. 250:276-279.
30. 2+ currents recorded with ancillary β1-4 subunits. Receptors Channels. 5:1-14.
31. 2+ channel pore. FEBS Lett. 335:265-269.
32. Miller, C. 1999. Ionic hopping defended. J. Gen. Physiol. 113:783-787.
33. 2+ channel. Biophys. J. 69:1801-1813.
34. Perez Reyes, E., L.L. Cribbs, A. Daud, A.E. Lacerda, J. Barclay, M.P. Williamson, M. Fox, M. Rees, and J.H. Lee. 1998. Molecular characterization of a neuronal low-voltage-activated T-type calcium channel. Nature. 391:896-900.
35. Rosenberg, R.L., and X.H. Chen. 1991. Characterization and localization of two ion-binding sites within the pore of cardiac L-type calcium channels. J. Gen. Physiol. 97:1207-1225.
36. Roux, B. 1999. Theories of ion permeation: a chaser. J. Gen. Physiol. 114:605-608.
37. Sather, W.A., and E.W. McCleskey. 2003. Permeation and selectivity in calcium channels. Annu. Rev. Physiol. 65:133-159.
38. Sather, W.A., J. Yang, and R.W. Tsien. 1994. Structural basis of ion channel permeation and selectivity. Curr. Opin. Neurobiol. 4:313-323.
39. 2+ selectivity of α1G T-type calcium channels. Biophys. J. 79:3052-3062.
40. 1G. J. Biol. Chem. 276:45628-45635.
41. 2+ channel α1G. J. Gen. Physiol. 121:529-540.
42. Tang, S., G. Mikala, A. Bahinski, A. Yatani, G. Varadi, and A. Schwartz. 1993. Molecular localization of ion selectivity sites within the pore of a human L-type cardiac calcium channel. J. Biol. Chem. 268:13026-13029.
43. Varadi, G., M. Strobeck, S. Koch, L. Caglioti, C. Zucchi, and G. Palyi. 1999. Molecular elements of ion permeation and selectivity within calcium channels. Crit. Rev. Biochem. Mol. Biol. 34:181-214.
44. 2+ channels. Biophys. J. 77:2575-2589.
45. 2+ channel. J. Biol. Chem. 275:31778-31785.
46. 2+ channels. Nature. 366:158-161.