Assessment of three human FcεRI-transfected RBL cell-lines for identifying IgE induced degranulation utilizing peanut-allergic patient sera and peanut protein extract

Regulatory Toxicology and Pharmacology

Volumn 51, Issue 3, 2008, Pages 288-294

  Ladics, G S ^a   van Bilsen, J H M ^b   Brouwer, H M H ^b   Vogel, L ^c   Vieths, S ^c   Knippels, L M J ^b  

^a DUPONT COMPANY   (United States)

^b TNO   (Netherlands)

^c PAUL EHRLICH INSTITUT   (Germany)

Author keywords

Biological activity; Human Fc RI; Humanized rat basophilic leukemia cells; Mediator release; Peanut allergic subjects; Protein cross reactivity

Indexed keywords

BETA N ACETYLHEXOSAMINIDASE; FC RECEPTOR; FOOD ALLERGEN; IMMUNOGLOBULIN E; ALLERGEN; IMMUNOGLOBULIN E RECEPTOR; PLANT EXTRACT;

ANIMAL CELL; ANTIGEN BINDING; ARTICLE; BASOPHIL DEGRANULATION; CONTROLLED STUDY; CROSS REACTION; FOOD SAFETY; HUMAN; NONHUMAN; PEANUT ALLERGY; PRIORITY JOURNAL; RAT; REPRODUCIBILITY; SERUM; ANIMAL; BLOOD; CHEMISTRY; CYTOLOGY; DEGRANULATION; DOSE RESPONSE; DRUG EFFECT; GENETIC TRANSFECTION; GENETICS; IMMUNOLOGY; MAST CELL; METABOLISM; METHODOLOGY; PEANUT; TUMOR CELL LINE;

ARACHIS HYPOGAEA; RATTUS;

ALLERGENS; ANIMALS; ARACHIS HYPOGAEA; BETA-N-ACETYLHEXOSAMINIDASES; CELL DEGRANULATION; CELL LINE, TUMOR; DOSE-RESPONSE RELATIONSHIP, IMMUNOLOGIC; HUMANS; IMMUNOGLOBULIN E; MAST CELLS; PEANUT HYPERSENSITIVITY; PLANT EXTRACTS; RATS; RECEPTORS, IGE; TRANSFECTION;

EID: 47749109064     PISSN: 02732300     EISSN: 10960295     Source Type: Journal    
DOI: 10.1016/j.yrtph.2008.04.012     Document Type: Article

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