Peanut allergen Ara h 3: Isolation from peanuts and biochemical characterization

Allergy: European Journal of Allergy and Clinical Immunology

Volumn 58, Issue 11, 2003, Pages 1144-1151

  Koppelman, S J ^a,b   Knol, E F ^b   Vlooswijk, R A A ^a   Wensing, M ^b   Knulst, A C ^b   Hefle, S L ^c   Gruppen, H ^a,d   Piersma, S ^a,e  

^a TNO   (Netherlands)

^b UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^c UNIVERSITY OF NEBRASKA LINCOLN   (United States)

^d WAGENINGEN UNIVERSITY   (Netherlands)

^e FOM INSTITUTE AMOLF   (Netherlands)

Author keywords

Allergens; IgE binding; Peanut; Purification

Indexed keywords

ALLERGEN; ARA H 3 ANTIGEN; COMPLEMENTARY DNA; GLYCININ; IMMUNOGLOBULIN E; PEANUT ANTIGEN; PROTEIN SUBUNIT; UNCLASSIFIED DRUG;

ALLERGENICITY; AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ANTIGEN BINDING; ARTICLE; BIOCHEMISTRY; ENZYME LINKED IMMUNOSORBENT ASSAY; GEL PERMEATION CHROMATOGRAPHY; NONHUMAN; PEANUT; PEANUT ALLERGY; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FOLDING; PROTEIN ISOLATION; PROTEIN PROCESSING; PROTEIN PURIFICATION; PROTEIN STRUCTURE; PROTEIN UNFOLDING; WESTERN BLOTTING;

ALLERGENS; AMINO ACID SEQUENCE; ARACHIS HYPOGAEA; CALORIMETRY, DIFFERENTIAL SCANNING; CHROMATOGRAPHY, ION EXCHANGE; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ENZYME-LINKED IMMUNOSORBENT ASSAY; HUMANS; IMMUNOBLOTTING; IMMUNOGLOBULIN E; PEANUT HYPERSENSITIVITY;

EID: 0242708816     PISSN: 01054538     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1398-9995.2003.00259.x     Document Type: Article

References (28)

1. SAMPSON HA, MCCASKILL CC. Food hypersensitivity and atopic dermatitis: Evaluation of 113 patients. J Pediatr (USA) 1985;107:669-675.
2. TARIQ SM, STEVENS M, MATTHEWS S, RIDOUT S, TWISELTON R, HIDE DW. Cohort study of peanut and tree nut sensitisation by age of 4 years. Br Med J 1996;313:514-517.
3. BARNETT D, HOWDEN ME. Partial characterization of an allergenic glycoprotein from peanut(Arachis hypogaea L.). Biochim Biophys Acta 1986;882:97-105.
4. BURKS AW, WILLIAMS LW, HELM RM, CONNAUGHTON C, COCKRELL G, O'BRIEN TJ. Identification of a major peanut allergen, Ara h I, in patients with atopic dermatitis and positive peanut challenges. J Allergy Clin Immunol 1991;88:172-179.
5. DE JONG EC, VAN ZIJVERDEN M, SPANHAAK S, KOPPELMAN SJ, PELLEGROM H, PENNINKS AH. Identification and partial characterization of multiple major allergens in peanut proteins. Clin Exp Allergy 1998;28:743-751.
6. BURKS AW, COCKRELL G, STANLEY JS, HELM RM, BANNON GA. Recombinant peanut allergen Ara h I expression and IgE binding in patients with peanut hypersensitivity. J Clin Invest 1995;96:1715-1721.
7. SHIN DS, COMPADRE CM, MALEKI SJ et al. Biochemical and structural analysis of the IgE binding sites on Ara h1, an abundant and highly allergenic peanut protein. J Biol Chem 1998;273:13753-13759.
8. KOPPELMAN SJ, BRUIJNZEEL-KOOMEN CAFM, HESSING M, DE JONGH HHJ. Heat-induced conformational changes of Ara h 1, a major peanut allergen, do not affect its allergenic properties. J Biol Chem 1999;274:4770-4777.
9. BURKS AW, WILLIAMS LW, CONNAUGHTON C, COCKRELL G, O'BRIEN TJ, HELM RM. Identification and characterization of a second major peanut allergen. Ara h II, with use of the sera of patients with atopic dermatitis and positive peanut challenge. J Allergy Clin Immunol 1992;90:962-969.
10. KLEBER-JANKE T, CRAMERI R, APPENZELLER U, SCHLAAK M, BECKER WM. Selective cloning of peanut allergens, including profilin and 2S albumins, by phage display technology. Int Arch Allergy Immunol 1999;119:265-274.
11. EIGENMANN PA, BURKS AW, BANNON GA. SAMPSON HA. Identification of unique peanut and soy allergens in sera adsorbed with cross-reacting antibodies. J Allergy Clin Immunol 1996;98:969-978.
12. RABJOHN P, HELM EM, STANLEY JS, et al. Molecular cloning and epitope analysis of the peanut allergen Ara h 3. J Clin Invest 1999;103:535-542.
13. STASWICK PE, HERMODSON MA, NIELSEN NC. Identification of the acidic and basic subunit complexes of glycinin. J Biol Chem 1981;256:8752-8755.
14. GATEHOUSE JA. CROY RRD, BOULTER D, BOYCE J. The synthesis and structure of pea storage proteins [Pisum sativum]. Crit Rev Plant Sci 1984;1:287-314.
15. LAEMMLI UK. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 1970;227:359-365.
16. TOWBIN HK, STAEHELIN TH, GORDON J. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets. Proc Natl Acad Sci USA 1979;76:4350-4354.
17. DESIMONE J, WU C-SC, BOULTER D. Legumin and vicilin,storage proteins of legume seeds. Phytochemistry 1976;15:3-24.
18. STASWICK PE, HERMODSON MA, NIELSEN NC. Identification of the acidic and basic subunit complexes of glycinin. J Biol Chem 1981;256:8752-8755.
19. BURKS W, SAMPSON HA, BANNON G. Peanut allergens. Allergy 1998;53:725-730.
20. BUSCHMANN L, PETERSEN A, SCHLAAK M, BECKER WM. Reinvestigation of the major peanut allergen Ara h 1 on molecular level. Monogr Allergy 1996;32:92-98.
21. KOPPELMAN SJ, VLOOSWIJK RAA, KNIPPELS LMJ, et al. Quantification of major peanut allergens Ara h 1 and Ara h 2 in the peanut varieties Runner. Spanish, Virginia, and Valencia, bred in different parts of the world. Allergy 2001;56:132-137.
22. STASWICK PE, HERMODSON MA, NIELSEN NC. Identification of the cystines which link the acidic and basic components of the glycinin subunits. J Biol Chem 1984;259:13431-13435.
23. IYNGKARAN N, RAYON C. New aspects of sub-unit structure of soybean glycinin. Cereal Chem 1981;58:325-330.
24. PEDERSEN HS, DJURTOFT R. Antigenic and allergenic properties of acidic and basic peptide chains from glycinin. Food Agricultural Immunol 1989;1:101-109.
25. HERIAN AM, TAYLOR SL, BUSH RK. Identification of soybean allergens by immunoblotting with sera from soyallergic adults. Int Arch Allergy Appl Immunol 1990;92:193-198.
26. BEARDSLEE TA, ZEECE MG, SARATH G, MARKWELL JP. Soybean glycinin G1 acidic chain shares IgE epitopes with peanut allergen Ara h 3. Int Arch Allergy Immunol 2000;123:299-307.
27. HELM RM, COCKRELL G, CONNAUGHTON C, et al. A soybean G2 glycinin allergen - 1. Identification and characterization. Int Arch Allergy Immunol 2000;123:205-212.
28. STANLEY JS, KING N, BURKS AW, et al. Identification and mutational analysis of the immunodominant IgE binding epitopes of the major peanut allergen Ara h 2. Arch Biochem Biophys 1997;342:244-253.