-
1
-
-
24944448983
-
Bcl-2 antisense oligonucleotide overcomes resistance to E1A gene therapy in a low HER2-expressing ovarian cancer xenograft model
-
C Bartholomeusz H Itamochi LX Yuan 2005 Bcl-2 antisense oligonucleotide overcomes resistance to E1A gene therapy in a low HER2-expressing ovarian cancer xenograft model Cancer Res 65 8406 8413
-
(2005)
Cancer Res
, vol.65
, pp. 8406-8413
-
-
Bartholomeusz, C.1
Itamochi, H.2
Yuan, L.X.3
-
2
-
-
0142029990
-
The role of Bcl-2 family members in the progression of cutaneous melanoma
-
JA Bush G Li 2003 The role of Bcl-2 family members in the progression of cutaneous melanoma Clin Exp Metastasis 20 531 539
-
(2003)
Clin Exp Metastasis
, vol.20
, pp. 531-539
-
-
Bush, J.A.1
Li, G.2
-
3
-
-
0037832626
-
P-glycoprotein and BCL-2 levels predict outcome in adult acute lymphoblastic leukaemia
-
MI Del Principe G Del Poeta L Maurillo 2003 P-glycoprotein and BCL-2 levels predict outcome in adult acute lymphoblastic leukaemia Br J Haematol 121 730 738
-
(2003)
Br J Haematol
, vol.121
, pp. 730-738
-
-
Del Principe, M.I.1
Del Poeta, G.2
Maurillo, L.3
-
4
-
-
0038748005
-
Bcl-2 as a target for overcoming chemoresistance in small-cell lung cancer
-
DA Fennell 2003 Bcl-2 as a target for overcoming chemoresistance in small-cell lung cancer Clin Lung Cancer 4 307 313
-
(2003)
Clin Lung Cancer
, vol.4
, pp. 307-313
-
-
Fennell, D.A.1
-
5
-
-
0037817461
-
Induction of apoptosis and chemosensitization of mesothelioma cells by Bcl-2 and Bcl-xL antisense treatment
-
S Hopkins-Donaldson R Cathomas AP Simoes-Wust 2003 Induction of apoptosis and chemosensitization of mesothelioma cells by Bcl-2 and Bcl-xL antisense treatment Int J Cancer 106 160 166
-
(2003)
Int J Cancer
, vol.106
, pp. 160-166
-
-
Hopkins-Donaldson, S.1
Cathomas, R.2
Simoes-Wust, A.P.3
-
6
-
-
0037206950
-
Resistance to chemotherapy via Stat3-dependent overexpression of Bcl-2 in metastatic breast cancer cells
-
PJ Real A Sierra A De Juan 2002 Resistance to chemotherapy via Stat3-dependent overexpression of Bcl-2 in metastatic breast cancer cells Oncogene 21 7611 7618
-
(2002)
Oncogene
, vol.21
, pp. 7611-7618
-
-
Real, P.J.1
Sierra, A.2
De Juan, A.3
-
7
-
-
0141869788
-
Expression of antisense bcl-2 cDNA abolishes tumorigenicity and enhances chemosensitivity of human malignant glioma cells
-
CJ Zhu YB Li MC Wong 2003 Expression of antisense bcl-2 cDNA abolishes tumorigenicity and enhances chemosensitivity of human malignant glioma cells J Neurosci Res 74 60 66
-
(2003)
J Neurosci Res
, vol.74
, pp. 60-66
-
-
Zhu, C.J.1
Li, Y.B.2
Wong, M.C.3
-
8
-
-
0029923503
-
Potentiation of enediyne-induced apoptosis and differentiation by Bcl-2
-
M Cortazzo NF Schor 1996 Potentiation of enediyne-induced apoptosis and differentiation by Bcl-2 Cancer Res 56 1199 1203
-
(1996)
Cancer Res
, vol.56
, pp. 1199-1203
-
-
Cortazzo, M.1
Schor, N.F.2
-
9
-
-
33644837259
-
Bcl-2-mediated potentiation of neocarzinostatin-induced apoptosis: Requirement for caspase-3, sulfhydryl groups, and cleavable Bcl-2
-
Z Mi B Hong ZK Mirnics 2006 Bcl-2-mediated potentiation of neocarzinostatin-induced apoptosis: requirement for caspase-3, sulfhydryl groups, and cleavable Bcl-2 Cancer Chemother Pharmacol 57 357 367
-
(2006)
Cancer Chemother Pharmacol
, vol.57
, pp. 357-367
-
-
Mi, Z.1
Hong, B.2
Mirnics, Z.K.3
-
10
-
-
0033549248
-
Selective oxidation and externalization of membrane phosphatidylserine: Bcl-2-induced potentiation of the final common pathway for apoptosis
-
NF Schor YY Tyurina JP Fabisiak 1999 Selective oxidation and externalization of membrane phosphatidylserine: Bcl-2-induced potentiation of the final common pathway for apoptosis Brain Res 831 125 130
-
(1999)
Brain Res
, vol.831
, pp. 125-130
-
-
Schor, N.F.1
Tyurina, Y.Y.2
Fabisiak, J.P.3
-
11
-
-
0034688306
-
Cell line dependence of Bcl-2-induced alteration of glutathione handling
-
NF Schor CM Rudin AR Hartman 2000 Cell line dependence of Bcl-2-induced alteration of glutathione handling Oncogene 19 472 476
-
(2000)
Oncogene
, vol.19
, pp. 472-476
-
-
Schor, N.F.1
Rudin, C.M.2
Hartman, A.R.3
-
12
-
-
0027717968
-
Bcl-2 inhibition of neural death: Decreased generation of reactive oxygen species
-
DJ Kane TA Sarafian R Anton 1993 Bcl-2 inhibition of neural death: decreased generation of reactive oxygen species Science 262 1274 1277
-
(1993)
Science
, vol.262
, pp. 1274-1277
-
-
Kane, D.J.1
Sarafian, T.A.2
Anton, R.3
-
13
-
-
0036140941
-
Role of caspase 3-dependent Bcl-2 cleavage in potentiation of apoptosis by Bcl-2
-
Y Liang KD Nylander C Yan 2002 Role of caspase 3-dependent Bcl-2 cleavage in potentiation of apoptosis by Bcl-2 Mol Pharmacol 61 142 149
-
(2002)
Mol Pharmacol
, vol.61
, pp. 142-149
-
-
Liang, Y.1
Nylander, K.D.2
Yan, C.3
-
14
-
-
0028863552
-
Induction of apoptosis in murine and human neuroblastoma cell lines by the enediyne natural product neocarzinostatin
-
TL Hartsell JC Yalowich MK Ritke 1995 Induction of apoptosis in murine and human neuroblastoma cell lines by the enediyne natural product neocarzinostatin J Pharmacol Exp Ther 275 479 485
-
(1995)
J Pharmacol Exp Ther
, vol.275
, pp. 479-485
-
-
Hartsell, T.L.1
Yalowich, J.C.2
Ritke, M.K.3
-
15
-
-
0033526785
-
Differential membrane antioxidant effects of immediate and long-term estradiol treatment of MCF-7 breast cancer cells
-
NF Schor YY Tyurina VA Tyurin 1999 Differential membrane antioxidant effects of immediate and long-term estradiol treatment of MCF-7 breast cancer cells Biochem Biophys Res Commun 260 410 415
-
(1999)
Biochem Biophys Res Commun
, vol.260
, pp. 410-415
-
-
Schor, N.F.1
Tyurina, Y.Y.2
Tyurin, V.A.3
-
17
-
-
0035319296
-
Introduction of mutant p53 into a wild-type p53-expressing glioma cell line confers sensitivity to Ad-p53-induced apoptosis
-
JA Cerrato WK Yung TJ Liu 2001 Introduction of mutant p53 into a wild-type p53-expressing glioma cell line confers sensitivity to Ad-p53-induced apoptosis Neuro Oncol 3 113 122
-
(2001)
Neuro Oncol
, vol.3
, pp. 113-122
-
-
Cerrato, J.A.1
Yung, W.K.2
Liu, T.J.3
-
18
-
-
38049074854
-
Medulloblastomas overexpress the p53-inactivating oncogene WIP1/PPM1D
-
RC Castellino M De Bortoli X Lu 2007 Medulloblastomas overexpress the p53-inactivating oncogene WIP1/PPM1D J Neuro-oncol 86 245 256
-
(2007)
J Neuro-oncol
, vol.86
, pp. 245-256
-
-
Castellino, R.C.1
De Bortoli, M.2
Lu, X.3
-
19
-
-
70349515561
-
Regulation of caspase-3 and Bcl-2 expression in Dalton's lymphoma ascites cells by abrin
-
(e-pub). doi:10.1093/ecam/nem099
-
Ramnath V, Rekha PS, Kuttan G, Kuttan R (2007) Regulation of caspase-3 and Bcl-2 expression in Dalton's lymphoma ascites cells by abrin. Evid-based Complement Alter Med (e-pub). doi:10.1093/ecam/nem099
-
(2007)
Evid-based Complement Alter Med
-
-
Ramnath, V.1
Rekha, P.S.2
Kuttan, G.3
Kuttan, R.4
-
20
-
-
47549107031
-
-
American Cancer Society (2007) What are the key statistics for brain and spinal cord tumors? http://www.cancer.org/docroot/CRI/content/ CRI_2_4_1X_What_are_the_key_statistics_for_brain_and_spinal_cord_tumors_3.asp? sitearea=
-
(2007)
What Are the Key Statistics for Brain and Spinal Cord Tumors?
-
-
-
21
-
-
0028857465
-
Brain tumors in children: Long-term survival after radiation treatment
-
D Jenkin M Greenberg H Hoffman 1995 Brain tumors in children: long-term survival after radiation treatment Int J Radiat Oncol Biol Phys 31 445 451
-
(1995)
Int J Radiat Oncol Biol Phys
, vol.31
, pp. 445-451
-
-
Jenkin, D.1
Greenberg, M.2
Hoffman, H.3
-
22
-
-
0032961066
-
Current aspects of biology, risk assessment, and treatment of neuroblastoma
-
GM Haase C Perez JB Atkinson 1999 Current aspects of biology, risk assessment, and treatment of neuroblastoma Semin Surg Oncol 16 91 104
-
(1999)
Semin Surg Oncol
, vol.16
, pp. 91-104
-
-
Haase, G.M.1
Perez, C.2
Atkinson, J.B.3
-
23
-
-
0034105523
-
Clinical prognostic factors in 1277 patients with neuroblastoma: Results of the European Neuroblastoma Study Group 'Survey' 1982-1992
-
SJ Cotterill AD Pearson J Pritchard 2000 Clinical prognostic factors in 1277 patients with neuroblastoma: results of The European Neuroblastoma Study Group 'Survey' 1982-1992 Eur J Cancer 36 901 908
-
(2000)
Eur J Cancer
, vol.36
, pp. 901-908
-
-
Cotterill, S.J.1
Pearson, A.D.2
Pritchard, J.3
-
24
-
-
0028322065
-
Bcl-2 inhibits chemotherapy-induced apoptosis in neuroblastoma
-
M Dole G Nunez AK Merchant 1994 Bcl-2 inhibits chemotherapy-induced apoptosis in neuroblastoma Cancer Res 54 3253 3259
-
(1994)
Cancer Res
, vol.54
, pp. 3253-3259
-
-
Dole, M.1
Nunez, G.2
Merchant, A.K.3
-
25
-
-
0028979439
-
Bcl-xL is expressed in neuroblastoma cells and modulates chemotherapy-induced apoptosis
-
MG Dole R Jasty MJ Cooper 1995 Bcl-xL is expressed in neuroblastoma cells and modulates chemotherapy-induced apoptosis Cancer Res 55 2576 2582
-
(1995)
Cancer Res
, vol.55
, pp. 2576-2582
-
-
Dole, M.G.1
Jasty, R.2
Cooper, M.J.3
-
26
-
-
0027164144
-
High expression of bcl-2 protein in acute myeloid leukemia cells is associated with poor response to chemotherapy
-
L Campos JP Rouault O Sabido 1993 High expression of bcl-2 protein in acute myeloid leukemia cells is associated with poor response to chemotherapy Blood 81 3091 3096
-
(1993)
Blood
, vol.81
, pp. 3091-3096
-
-
Campos, L.1
Rouault, J.P.2
Sabido, O.3
-
27
-
-
0028114913
-
Bcl-2 protein expression in tumors of the central nervous system
-
S Nakasu Y Nakasu H Nioka 1994 Bcl-2 protein expression in tumors of the central nervous system Acta Neuropathol 88 520 526
-
(1994)
Acta Neuropathol
, vol.88
, pp. 520-526
-
-
Nakasu, S.1
Nakasu, Y.2
Nioka, H.3
-
28
-
-
0029157380
-
Estrogen promotes chemotherapeutic drug resistance by a mechanism involving Bcl-2 proto-oncogene expression in human breast cancer cells
-
C Teixeira JC Reed MA Pratt 1995 Estrogen promotes chemotherapeutic drug resistance by a mechanism involving Bcl-2 proto-oncogene expression in human breast cancer cells Cancer Res 55 3902 3907
-
(1995)
Cancer Res
, vol.55
, pp. 3902-3907
-
-
Teixeira, C.1
Reed, J.C.2
Pratt, M.A.3
-
29
-
-
0008920702
-
Bcl-2 expression is associated with resistance to chemotherapy in advanced breast cancer
-
A Bonetti M Zaninelli F Pavanel 1996 Bcl-2 expression is associated with resistance to chemotherapy in advanced breast cancer Proc Am Assoc Cancer Res 37 192
-
(1996)
Proc Am Assoc Cancer Res
, vol.37
, pp. 192
-
-
Bonetti, A.1
Zaninelli, M.2
Pavanel, F.3
-
30
-
-
84996702994
-
Bcl-2 confers resistance to androgen deprivation in prostate carcinoma cells
-
AW TJ Beham McDonnell 1996 Bcl-2 confers resistance to androgen deprivation in prostate carcinoma cells Proc Am Assoc Cancer Res 37 224
-
(1996)
Proc Am Assoc Cancer Res
, vol.37
, pp. 224
-
-
Tj, W.A.1
B.mcdonnell2
-
31
-
-
0031984216
-
BCL-X expression in multiple myeloma: Possible indicator of chemoresistance
-
Y Tu S Renner F Xu 1998 BCL-X expression in multiple myeloma: possible indicator of chemoresistance Cancer Res 58 256 262
-
(1998)
Cancer Res
, vol.58
, pp. 256-262
-
-
Tu, Y.1
Renner, S.2
Xu, F.3
-
32
-
-
2942666279
-
G3139, a Bcl-2 antisense oligodeoxynucleotide, induces clinical responses in VAD refractory myeloma
-
NW van de Donk O de Weerdt G Veth 2004 G3139, a Bcl-2 antisense oligodeoxynucleotide, induces clinical responses in VAD refractory myeloma Leukemia 18 1078 1084
-
(2004)
Leukemia
, vol.18
, pp. 1078-1084
-
-
Van De Donk, N.W.1
De Weerdt, O.2
Veth, G.3
-
33
-
-
12344266609
-
Expression of Bcl-xL in ovarian carcinoma is associated with chemoresistance and recurrent disease
-
J Williams PC Lucas KA Griffith 2005 Expression of Bcl-xL in ovarian carcinoma is associated with chemoresistance and recurrent disease Gynec Oncol 96 287 295
-
(2005)
Gynec Oncol
, vol.96
, pp. 287-295
-
-
Williams, J.1
Lucas, P.C.2
Griffith, K.A.3
-
34
-
-
27744458685
-
Expression of p53, EGFR, pRb and bcl-2 proteins in pediatric glioblastoma multiforme: A study of 54 patients
-
PM Ganigi V Santosh B Anandh 2005 Expression of p53, EGFR, pRb and bcl-2 proteins in pediatric glioblastoma multiforme: a study of 54 patients Pediatr Neurosurg 41 292 299
-
(2005)
Pediatr Neurosurg
, vol.41
, pp. 292-299
-
-
Ganigi, P.M.1
Santosh, V.2
Anandh, B.3
-
35
-
-
0028018106
-
Bcl-2 protects from oxidative damage and apoptotic cell death without interfering with activation of NF-kappa B by TNF
-
H Albrecht J Tschopp CV Jongeneel 1994 Bcl-2 protects from oxidative damage and apoptotic cell death without interfering with activation of NF-kappa B by TNF FEBS Lett 351 45 48
-
(1994)
FEBS Lett
, vol.351
, pp. 45-48
-
-
Albrecht, H.1
Tschopp, J.2
Jongeneel, C.V.3
-
36
-
-
0031571582
-
Direct evidence for antioxidant effect of Bcl-2 in PC12 rat pheochromocytoma cells
-
YY Tyurina VA Tyurin G Carta 1997 Direct evidence for antioxidant effect of Bcl-2 in PC12 rat pheochromocytoma cells Arch Biochem Biophys 344 413 423
-
(1997)
Arch Biochem Biophys
, vol.344
, pp. 413-423
-
-
Tyurina, Y.Y.1
Tyurin, V.A.2
Carta, G.3
-
37
-
-
0042836587
-
Bcl-2 mediates induction of neural differentiation
-
Y Liang ZK Mirnics C Yan 2003 Bcl-2 mediates induction of neural differentiation Oncogene 22 5515 5518
-
(2003)
Oncogene
, vol.22
, pp. 5515-5518
-
-
Liang, Y.1
Mirnics, Z.K.2
Yan, C.3
-
38
-
-
4344625883
-
A critical role of glutathione in determining apoptosis sensitivity and resistance in leukemia cells
-
Suppl 1
-
C Friesen Y Kiess KM Debatin 2004 A critical role of glutathione in determining apoptosis sensitivity and resistance in leukemia cells Cell Death Differ 11 Suppl 1 S73 85
-
(2004)
Cell Death Differ
, vol.11
, pp. 73-85
-
-
Friesen, C.1
Kiess, Y.2
Debatin, K.M.3
-
39
-
-
0038297002
-
The late increase in intracellular free radical oxygen species during apoptosis is associated with cytochrome c release, caspase activation, and mitochondrial dysfunction
-
Q Chen YC Chai S Mazumder 2003 The late increase in intracellular free radical oxygen species during apoptosis is associated with cytochrome c release, caspase activation, and mitochondrial dysfunction Cell Death Differ 10 323 334
-
(2003)
Cell Death Differ
, vol.10
, pp. 323-334
-
-
Chen, Q.1
Chai, Y.C.2
Mazumder, S.3
-
40
-
-
26944498689
-
The intracellular domain of p75NTR as a determinant of cellular reducing potential and response to oxidant stress
-
YY Tyurina KD Nylander ZK Mirnics 2005 The intracellular domain of p75NTR as a determinant of cellular reducing potential and response to oxidant stress Aging Cell 4 187 196
-
(2005)
Aging Cell
, vol.4
, pp. 187-196
-
-
Tyurina, Y.Y.1
Nylander, K.D.2
Mirnics, Z.K.3
-
41
-
-
0031036872
-
Prevention of apoptosis by Bcl-2: Release of cytochrome c from mitochondria blocked
-
J Yang X Liu K Bhalla 1997 Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked Science 275 1129 1132
-
(1997)
Science
, vol.275
, pp. 1129-1132
-
-
Yang, J.1
Liu, X.2
Bhalla, K.3
-
42
-
-
0031037897
-
The release of cytochrome c from mitochondria: A primary site for Bcl-2 regulation of apoptosis
-
RM Kluck E Bossy-Wetzel DR Green 1997 The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis Science 275 1132 1136
-
(1997)
Science
, vol.275
, pp. 1132-1136
-
-
Kluck, R.M.1
Bossy-Wetzel, E.2
Green, D.R.3
-
43
-
-
0343340396
-
Redox control of caspase-3 activity by thioredoxin and other reduced proteins
-
A Baker BD Santos G Powis 2000 Redox control of caspase-3 activity by thioredoxin and other reduced proteins Biochem Biophys Res Commun 268 78 81
-
(2000)
Biochem Biophys Res Commun
, vol.268
, pp. 78-81
-
-
Baker, A.1
Santos, B.D.2
Powis, G.3
-
44
-
-
0030435331
-
Determinants of the response of neuroblastoma cells to DNA damage: The roles of pre-treatment cell morphology and chemical nature of the damage
-
TL Hartsell LM Hinman PR Hamann 1996 Determinants of the response of neuroblastoma cells to DNA damage: the roles of pre-treatment cell morphology and chemical nature of the damage J Pharmacol Exp Ther 277 1158 1166
-
(1996)
J Pharmacol Exp Ther
, vol.277
, pp. 1158-1166
-
-
Hartsell, T.L.1
Hinman, L.M.2
Hamann, P.R.3
-
45
-
-
0017364886
-
Single-strand nicking of DNA in vitro by neocarzinostatin and its possible relationship to the mechanism of drug action
-
TA Beerman R Poon IH Goldberg 1977 Single-strand nicking of DNA in vitro by neocarzinostatin and its possible relationship to the mechanism of drug action Biochim Biophys Acta 475 294 306
-
(1977)
Biochim Biophys Acta
, vol.475
, pp. 294-306
-
-
Beerman, T.A.1
Poon, R.2
Goldberg, I.H.3
-
46
-
-
0022387875
-
Glutathione dependence of neocarzinostatin cytotoxicity and mutagenicity in Chinese hamster V-79 cells
-
WG DeGraff JB Mitchell 1985 Glutathione dependence of neocarzinostatin cytotoxicity and mutagenicity in Chinese hamster V-79 cells Cancer Res 45 4760 4762
-
(1985)
Cancer Res
, vol.45
, pp. 4760-4762
-
-
Degraff, W.G.1
Mitchell, J.B.2
-
47
-
-
0026533105
-
Targeted enhancement of the biological activity of the antineoplastic agent, neocarzinostatin. Studies in murine neuroblastoma cells
-
NF Schor 1992 Targeted enhancement of the biological activity of the antineoplastic agent, neocarzinostatin. Studies in murine neuroblastoma cells J Clin Invest 89 774 781
-
(1992)
J Clin Invest
, vol.89
, pp. 774-781
-
-
Schor, N.F.1
-
48
-
-
0032541132
-
Detection of pro-caspase-3 in cytosol and mitochondria of various tissues
-
A Samali B Zhivotovsky DP Jones 1998 Detection of pro-caspase-3 in cytosol and mitochondria of various tissues FEBS Lett 431 167 169
-
(1998)
FEBS Lett
, vol.431
, pp. 167-169
-
-
Samali, A.1
Zhivotovsky, B.2
Jones, D.P.3
-
49
-
-
0035807288
-
Apoptosis in the absence of caspase 3
-
Y Liang C Yan NF Schor 2001 Apoptosis in the absence of caspase 3 Oncogene 20 6570 6578
-
(2001)
Oncogene
, vol.20
, pp. 6570-6578
-
-
Liang, Y.1
Yan, C.2
Schor, N.F.3
|