Expression of Stra13 during mouse endochondral bone development

Gene Expression Patterns

Volumn 4, Issue 6, 2004, Pages 633-636

  MacLean, Helen E ^a,b   Kronenberg, Henry M ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

bHLH; Cartilage; Chondrocyte; DEC1; Endochondral bone; HIF1 ; Hypoxia; Stra13; VEGF

Indexed keywords

COLLAGEN TYPE 10; HELIX LOOP HELIX PROTEIN; MESSENGER RNA; PROTEIN STRA13; UNCLASSIFIED DRUG; VASCULOTROPIN;

ARTICLE; BONE DEVELOPMENT; CARTILAGE CELL; CELL PROLIFERATION; CONTROLLED STUDY; EMBRYO; EMBRYO DEVELOPMENT; ENCHONDRAL OSSIFICATION; GENE TARGETING; GROWTH PLATE; HYPOXIA; IN SITU HYBRIDIZATION; MITOSIS; MOUSE; NONHUMAN; POSTNATAL DEVELOPMENT; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; TIBIA;

ANIMALS; ANOXIA; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; BONE AND BONES; BONE DEVELOPMENT; CARTILAGE; CHONDROCYTES; COLLAGEN TYPE X; DNA-BINDING PROTEINS; EMBRYONIC DEVELOPMENT; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HOMEODOMAIN PROTEINS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; IN SITU HYBRIDIZATION; MICE; MICE, INBRED C57BL; RNA, MESSENGER; TIME FACTORS; TRANSCRIPTION FACTORS; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 4744339322     PISSN: 1567133X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.modgep.2004.04.011     Document Type: Article

References (14)

1. Boudjelal M. Taneja R. Matsubara S. Bouillet P. Dolle P. Chambon P. Overexpression of Stra13, a novel retinoic acid-inducible gene of the basic helix-loop-helix family, inhibits mesodermal and promotes neuronal differentiation of P19 cells Genes Dev. 11 1997 2052-2065
2. Gerber H.P. Vu T.H. Ryan A.M. Kowalski J. Werb Z. Ferrara N. VEGF couples hypertrophic cartilage remodeling, ossification and angiogenesis during endochondral bone formation Nat. Med. 5 1999 623-628
3. Ivanova A.V. Ivanov S.V. Danilkovitch-Miagkova A. Lerman M.I. Regulation of STRA13 by the von Hippel-Lindau tumor suppressor protein, hypoxia, and the UBC9/ubiquitin proteasome degradation pathway J. Biol. Chem. 276 2001 15306-15315
4. Karsenty G. Wagner E.F. Reaching a genetic and molecular understanding of skeletal development Dev. Cell 2 2002 389-406
5. MacLean H.E. Kim J.I. Glimcher M.J. Wang J. Kronenberg H.M. Glimcher L.H. Absence of transcription factor c-maf causes abnormal terminal differentiation of hypertrophic chondrocytes during endochondral bone development Dev. Biol. 262 2003 51-63
6. Miyazaki K. Kawamoto T. Tanimoto K. Nishiyama M. Honda H. Kato Y. Identification of functional hypoxia response elements in the promoter region of the DEC1 and DEC2 genes J. Biol. Chem. 277 2002 47014-47021
7. Pfander D. Kobayashi T. Knight M.C. Zelzer E. Chan D. Olsen B.R. Giaccia A.J. Johnson R.S. Haase V.H. Schipani E. Deletion of Vhlh in chondrocytes reduces cell proliferation and increases matrix deposition during growth plate development Development 2004 131, 2497-2508
8. Schipani E. Ryan H.E. Didrickson S. Kobayashi T. Knight M. Johnson R.S. Hypoxia in cartilage: HIF-1α is essential for chondrocyte growth arrest and survival Genes Dev. 15 2001 2865-2876
9. Shen M. Kawamoto T. Yan W. Nakamasu K. Tamagami M. Koyano Y. Noshiro M. Kato Y. Molecular characterization of the novel basic helix-loop-helix protein DEC1 expressed in differentiated human embryo chondrocytes Biochem. Biophys. Res. Commun. 236 1997 294-298
10. Shen M. Yoshida E. Yan W. Kawamoto T. Suardita K. Koyano Y. Fujimoto K. Noshiro M. Kato Y. Basic helix-loop-helix protein DEC1 promotes chondrocyte differentiation at the early and terminal stages J. Biol. Chem. 277 2002 50112-50120
11. Sun H. Taneja R. Stra13 expression is associated with growth arrest and represses transcription through histone deacetylase (HDAC)-dependent and HDAC-independent mechanisms Proc. Natl Acad. Sci. USA 97 2000 4058-4063
12. Sun H. Lu B. Li R.Q. Flavell R.A. Taneja R. Defective T cell activation and autoimmune disorder in Stra13-deficient mice Nat. Immunol. 2 2001 1040-1047
13. Vortkamp A. Lee K. Lanske B. Segre G.V. Kronenberg H.M. Tabin C.J. Regulation of rate of cartilage differentiation by Indian hedgehog and PTH-related protein Science 273 1996 613-622
14. Zelzer E. Mamluk R. Ferrara N. Johnson R.S. Schipani E. Olsen B.R. VEGFA is necessary for chondrocyte survival during bone development Development 2004 131, 2161-2171