Correlation between dopamine D2 receptors in the ventral striatum and central processing of alcohol cues and craving

American Journal of Psychiatry

Volumn 161, Issue 10, 2004, Pages 1783-1789

  Heinz, Andreas ^b   Siessmeier, Thomas ^b   Wrase, Jana ^b   Hermann, Derik ^b   Klein, Sabine ^b   Grüsser Sinopoli, Sabine M ^b   Flor, Herta ^b   Braus, Dieter F ^b   Buchholz, Hans Georg ^b   Gründer, Gerhard ^b   Schreckenberger, Mathias ^b   Smolka, Michael N ^b   Rösch, Frank ^b   Mann, Karl ^a   Bartenstein, Peter ^b  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOL; DOPAMINE 2 RECEPTOR; RADIOLIGAND;

ADULT; ALCOHOL CONSUMPTION; ALCOHOLISM; ARTICLE; ASSOCIATION; ATTENTION; BEHAVIOR CONTROL; CINGULATE GYRUS; CLINICAL ARTICLE; CONTROLLED STUDY; CORPUS STRIATUM; CORRELATION ANALYSIS; DETOXIFICATION; DISEASE SEVERITY; DOPAMINE RELEASE; DOPAMINERGIC ACTIVITY; DOWN REGULATION; HUMAN; HUMAN TISSUE; MALE; NERVE CELL NETWORK; NUCLEAR MAGNETIC RESONANCE IMAGING; NUCLEUS ACCUMBENS; POSITRON EMISSION TOMOGRAPHY; PREFRONTAL CORTEX; PRIORITY JOURNAL; RECEPTOR SENSITIVITY; RECURRENCE RISK; RELAPSE; REWARD; SIGNAL DETECTION; STIMULUS; VISUAL STIMULATION;

EID: 4744337844     PISSN: 0002953X     EISSN: None     Source Type: Journal    
DOI: 10.1176/ajp.161.10.1783     Document Type: Article

References (42)

1. Robbins TW, Everitt BJ: Neurobehavioral mechanisms of reward and motivation. Curr Opin Neurobiol 1996; 6:228-236
2. Koob GF, Le Moal M: Drug abuse: hedonic homeostatic dysregulation. Science 1997; 278:52-58
3. Wise RA: Actions of drugs of abuse on the brain reward systems. Pharmacol Biochem Behav 1980; 13:213-223
4. Robinson TE, Berridge KC: The neural basis of drug craving: an incentive-sensitization theory of addiction. Brain Res Rev 1993; 18:247-291
5. Schultz W, Dayan P, Montague PR: A neural substrate of prediction and reward. Science 1997; 275:1593-1599
6. Fiorillo CD, Tobler PN, Schultz W: Discrete coding of reward probability and uncertainty by dopamine neurons. Science 2003; 299:1898-1902
7. Alexander GE, DeLong MR, Strick PL: Parallel organization of functionally segregated circuits linking basal ganglia and cortex. Ann Rev Neurosci 1986; 9:357-381
8. Haber SN, Fudge JL, McFarland NR: Striatonigrostriatal pathways in primates form an ascending spiral from the shell to the dorsolateral striatum. J Neurosci 2000; 20:2369-2382
9. Breiter HC, Gollub RL, Weisskoff RM, Kennedy DN, Makris N, Berke JD, Goodman JM, Kantor HL, Gastfried DR, Riorden JP, Mathew RT, Rosen BR, Hyman SE: Acute effects of cocaine on human brain activity and emotion. Neuron 1997; 19:591-611
10. Tzschentke TM: Measuring reward with the conditioned place preference paradigm: a comprehensive review of drug effects, recent progress and new issues. Prog Neurobiol 1998; 56:613-672
11. Ito R, Dalley JW, Robbins TW, Everitt BJ: Dopamine release in the dorsal striatum during cocaine seeking behavior under the control of a drug-associated cue. J Neurosci 2002; 22:6247-6253
12. Volkow ND, Wang GJ, Fowler JS, Logan J, Hitzmann R, Ding YS, Pappas N, Shea C, Piscani K: Decreases in dopamine receptors but not in dopamine transporters in alcoholics. Alcohol Clin Exp Res 1996; 20:1594-1598
13. Dettling M, Heinz A, Dufeu P, Rommelspacher H, Gräf K-J, Schmidt LG: Dopaminergic responsivity in alcoholism: trait, state, or residual marker? Am J Psychiatry 1995; 152:1317-1321
14. Heinz A, Dufeu P, Kuhn S, Dettling M, Graf K, Kurten I, Rommelspacher H, Schmidt LG: Psychopathological and behavioral correlates of dopaminergic sensitivity in alcohol-dependent patients. Arch Gen Psychiatry 1996; 53:1123-1128
15. George DT, Rawlings R, Eckhardt MJ, Phillips MJ, Shoaf S, Linnoila M: Buspirone treatment of alcoholism: age of onset, and cerebrospinal fluid 5-hydroxyindoleacetic acid and homovanillic acid concentrations, but not medication treatment, predict return to drinking. Alcohol Clin Exp Res 1999; 23:272-278
16. First MB, Spitzer RL, Gibbon M, Williams JB: Structured Clinical Interview for DSM-IV-TR Axis I Disorders, Research Version, Patient Edition With Psychotic Screen (SCID-I/P W/ PSY SCREEN). New York, New York State Psychiatric Institute, Biometrics Research, 2001
17. First MB, Gibbon M, Spitzer RL, Williams JB, Benjamin L: Structured Clinical Interview for DSM-IV Personality Disorders (SCID-II): Interview and Questionnaire. Washington, DC, American Psychiatric Press, 1997
18. Singleton EG, Henningfield JE, Tiffany ST: Alcohol Craving Questionnaire (ACQ-NOW): Background and Administration Manual. Baltimore, National Institute on Drug Abuse, Addiction Research Center, 1994
19. Gründer G, Siessmeier T, Piel M, Vernaleken I, Buchholz HG, Zhou Y, Hiemke C, Wong D, Roesch F, Bartenstein P: Quantification of D2-like dopamine receptors in the human brain with [18F]desmethoxyfallypride. J Nucl Med 2003; 44:109-116
20. Gunn RN, Lammertsma AA, Hume SP, Cunningham, VJ: Parametric imaging of ligand-receptor binding in PET using a simplified reference region model. Neuroimage 1997; 6:279-287
21. Talairach J, Tournoux P: Co-Planar Stereotaxic Atlas of the Human Brain: Three-Dimensional Proportional System. New York, Thieme Medical, 1988
22. Friston KJ, Holmes AP, Worsley K, Poline JB, Frith CD, Frackowiak RSJ: Statistical parametric maps in functional brain imaging: a general linear approach. Hum Brain Mapp 1995; 2:189-210
23. Grüsser SM, Heinz A, Flor H: Standardized stimuli to assess drug craving and drug memory in addicts. J Neural Transm 2000; 107:715-720
24. Wrase J, Grüsser SM, Klein S, Diener C, Hermann D, Flor H, Mann K, Braus DF, Heinz A: Development of alcohol-associated cues and cue-induced brain activation in alcoholics. Eur Psychiatry 2002; 17:287-291
25. Center for the Study of Emotion and Attention. (CSEA:NIMH): The International Affective Picture System (photographic slides). Gainesville, University of Florida, Center for Research in Psychophysiology, 1999
26. Taylor SF, Phan KL, Decker LR, Liberzon I: Subjective rating of emotionally salient stimuli modulates neural activity. Neuroimage 2003; 18:650-659
27. Bradley MM, Lang PJ: Measuring emotion: the Self-Assessment Manikin and the Semantic Differential. J Behav Ther Exp Psychiatry 1994; 25:49-59
28. Maas LC, Lukas SE, Kaufman MJ, Weiss RD, Daniels SL, Rogers VW, Kukes TJ, Renshaw PF: Functional magnetic resonance imaging of human brain activation during cue-induced cocaine craving. Am J Psychiatry 1998; 155:124-126
29. Childress AR, Mozley PD, McElgin W, Fitzgerald J, Reivich M, O'Brien CP: Limbic activation during cue-induced cocaine craving. Am J Psychiatry 1999; 156:11-18
30. Garavan H, Pankiewicz J, Bloom A, Cho J-K, Sperry L, Ross TJ, Salmeron BJ, Risinger R, Kelley D, Stein EA: Cue-induced cocaine craving: neuroanatomical specificity for drug users and drug stimuli. Am J Psychiatry 2000; 157:1789-1798
31. Kilts CD, Schweitzer JB, Quinn CK, Gross RE, Faber TL, Muhammad F, Ely TD, Hoffman JM, Drexler KP: Neural activity related to drug craving in cocaine addiction. Arch Gen Psychiatry 2001; 58:334-341
32. Wexler BE, Gottschalk CH, Fulbright RK, Prohovnik I, Lacadie CM, Rounsaville BJ, Gore JC: Functional magnetic resonance imaging of cocaine craving. Am J Psychiatry 2001; 158:86-95
33. George MS, Anton RF, Bloomer C, Teneback C, Drobes DJ, Lorberbaum JP, Nahas Z, Vincent DJ: Activation of prefrontal cortex and anterior thalamus in alcoholic subjects on exposure to alcohol-specific cues. Arch Gen Psychiatry 2001; 58:345-352
34. Braus DF, Wrase J, Grüsser SM, Hermann D, Ruf M, Flor H, Mann K, Heinz A: Alcohol-associated stimuli activate the ventral striatum in abstinent alcoholics. J Neural Transm 2001; 108:887-894
35. Haber SN, McFarland NR: The concept of the ventral striatum in nonhuman primates. Ann NY Acad Sci 1999; 877:33-48
36. Mawlawi O, Martinez D, Slifstein M, Broft A, Chatterjee R, Hwang DR, Huang Y, Simpson N, Ngo K, van Heertum R, Laruelle M: Imaging human mesolimbic dopamine transmission with positron emission tomography, I: accuracy and precision of D(2) receptor parameter measurements in ventral striatum. J Cereb Blood Flow Metab 2001; 21:1034-1057
37. Stockwell T, Hodgson R, Edwards G, Taylor C, Rankin H: The development of a questionnaire to measure severity of alcohol dependence. Br J Addict 1979; 74:79-87
38. Skinner HA, Sheu WJ: Reliability of alcohol use indices: the Lifetime Drinking History and the MAST. J Stud Alcohol 1982; 43:1157-1170
39. O'Reilly RC, Noelle DC, Braver TS, Cohen JD: Prefrontal cortex and dynamic categorization tasks: representational organization and neuromodulatory control. Cereb Cortex 2002; 12:246-257
40. Contreras-Vidal JL, Schultz W: A predictive reinforcement model of dopamine neurons for learning approach behavior. J Comput Neurosci 1999; 6:191-214
41. Fuster JM: The Prefrontal Cortex: Anatomy, Physiology, and Neuropsychology of the Frontal Lobe. Philadelphia, Lippincott-Raven, 1997
42. Volkow ND, Fowler JS: Addiction, a disease of compulsion and drive: involvement of the orbitofrontal cortex. Cereb Cortex 2000; 10:318-325