Psychopathological and behavioral correlates of dopaminergic sensitivity in alcohol-dependent patients

Archives of General Psychiatry

Volumn 53, Issue 12, 1996, Pages 1123-1128

  Heinz, Andreas ^a,b   Dufeu, Peter ^a   Kuhn, Silke ^a   Dettling, Michael ^a   Gräf, Klaus ^a   Kürten, Irene ^a   Rommelspacher, Hans ^a   Schmidt, Lutz G ^a  

^a FREIE UNIVERSITÄT BERLIN   (Germany)

^b NATIONAL INSTITUTE OF MENTAL HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOL; APOMORPHINE; CLOMETHIAZOLE; DOPAMINE RECEPTOR; GROWTH HORMONE;

ADULT; ALCOHOLISM; ANXIETY; ARTICLE; CONTROLLED STUDY; DEPRESSION; DETOXIFICATION; DOPAMINERGIC TRANSMISSION; FEMALE; GROWTH HORMONE RELEASE; HUMAN; MAJOR CLINICAL STUDY; MALE; RATING SCALE; RELAPSE; SUBCUTANEOUS DRUG ADMINISTRATION; TREATMENT OUTCOME; WITHDRAWAL SYNDROME;

EID: 0029730627     PISSN: 0003990X     EISSN: None     Source Type: Journal    
DOI: 10.1001/archpsyc.1996.01830120061011     Document Type: Article

References (32)

1. Mereu G, Fadda F, Gessa GL. Ethanol stimulates the firing rate of nigral dopaminergic neurons in unanesthetized rats. Brain Res. 1984;292:63-69.
2. Imperato A, Di Chiara G. Preferential stimulation of dopamine release in the nucleus accumbens of freely moving rats by ethanol. J Pharmacol Exp Ther. 1986;239:219-228.
3. Wise RA. The neurobiology of craving: implications for the understanding and treatment of addiction. J Abnorm Psychol. 1988;97:118-132.
4. Tabakoff B, Kiianmaa K. Does tolerance develop to the activating, as well as the depressant, effects of ethanol? Pharmacol Biochem Behav 1982;17:1073-1076.
5. Wise RA, Bozarth MA. A psychomotor stimulant theory of addiction. Psychol Rev. 1987;94:469-492.
6. Cloninger CR. A systematic method for clinical description and classification of personality variants: a proposal. Arch Gen Psychiatry. 1987;44:573-588.
7. Cloninger CR. Neurogenetic adaptive mechanisms in alcoholism. Science. 1987; 236:410-416.
8. Schuckit MA, Parker DC, Rossman LR. Ethanol-related prolactin responses and risk for aicoholism. Biol Psychiatry. 1983;18:1153-1159.
9. Balldin J, Alling C, Gottfries CG, Lindtstedt G, Langström G. Changes in dopamine receptor sensitivity in humans after heavy ethanol intake. Psychopharmacology. 1985;86:142-146.
10. Balldin JI, Berggren UC, Lindstedt G. Neuroendocrine evidence for reduced dopamine receptor sensitivity in alcoholism. Alcohol Clin Exp Res. 1992;16: 71-74.
11. Balldin J, Berggren U, Lindstedt G, Sundkler A Further neuroendocrine evidence for reduced D2 dopamine receptor function in alcoholism. Drug Alcohol Depend. 1993;32:159-162.
12. Heinz A, Dettling M, Kuhn S, Gräf KJ, Kürten I, Rommelspacher H, Schmidt LG. Blunted growth hormone response is associated with early relapse in alcohol-dependent patients. Alcohol Exp Clin Res. 1995;19:62-65.
13. Rossetti ZL, Melis F, Carboni S, Diana M, Gessa GL. Alcohol withdrawal in rats is associated with a marked decrease in extraneuronal dopamine. Alcohol Clin Exp Res. 1992;16:529-532.
14. Heinz A, Schmidt LG, Reischies FM. Anhedonia in schizophrenic, depressed, or alcohol-dependent patients: neurobiological correlates. Pharmacopsychiatry. 1994;27(suppl):7-10.
15. Aneshensel CS, Huba GJ. Depression, alcohol use, and smoking over one year: a four-wave longitudinal causal model. J Abnorm Psychol. 1983;92: 134-150.
16. Rounsaville BJ, Dolinsky ZS, Babor TF, Meyer RE. Psychopathology as a predictor of treatment outcome in alcoholics. Arch Gen Psychiatry. 1987;44:505-513.
17. O'Sullivan K, Rynne C, Miller J, O'Sullivan S, Fitzpatrick V, Hux M, Cooney J, Clare A. A follow-up study on alcoholics with and without co-existing affective disorder. Br J Psychiatry. 1988;152:813-819.
18. Glenn SW, Parsons OA. Prediction of resumption of drinking in posttreatment alcoholics Int J Addict. 1991;26:237-254.
19. World Health Organization. International Classification of Diseases, 10th Revision Göttingen, Germany: Huber: 1991.
20. Robins LN, Wing J, Wittchen HU, Helzer JE, Babor TF, Burke J, Farmer A, Jablenski A, Pickens R, Regier DA. The Composite International Diagnostic Interview: an epidemiological instrument suitable for use in conjunction with different diagnostic systems and in different cultures Arch Gen Psychiatry. 1988;45:1069-1077.
21. Overall JE, Gorharn DR. The Brief Psychiatric Rating Scale. Psychol Rep 1962; 10:799-812.
22. Rommelspacher H, Raeder C, Kaulen P, Brüning G. Adaptive changes of dopamine-D2 receptors in rat brain following ethanol withdrawal: a quantitative autoradiographic investigation. Alcohol. 1992;9:355-362.
23. Stibler H, Borg S, Joustra M. Micro anion exchange chromatography of carbohydrate-deficient transferrin in serum in relation to alcohol consumption. Alcohol Clin Exp Res. 1986;10:535-544.
24. Sullivan JT, Sykora K, Schneiderman J, Narkanjo CA, Sellers EM. Assessment of alcohol withdrawal: the revised Clinical Institute Withdrawal Assessment for Alcohol Scale (CIWA-Ar). Br J Addict. 1989;84:1353-1357.
25. Majumdar SK. The influence of chlormethiazole on the neuroendocrine system in chronic alcoholics. Acta Psychiatr Scand Suppl. 1986;329:69-72.
26. Zung WWK. A rating instrument for anxiety disorders. Psychosomatics. 1971; 12:371-379.
27. Zung WWK. A Self-rating Depression Scale. Arch Gen Psychiatry. 1965;12: 63-70.
28. George DT, Lindquist T, Rawlings RR, Eckhardt MJ, Moss H, Mathis C, Martin PR, Linnoila M. Pharmacologic maintenance of abstinence in patients with alcoholism: no efficacy of 5-hydroxytryptophan or levodopa. Clin Pharmacol Ther 1992;52:553-560.
29. Dettling M, Heinz A, Dufeu P, Rommelspacher H, Graf KJ, Schmidt LG. Dopaminergic responsivity in alcoholism: trait-, state- or residual marker? Am J Psychiatry 1995;152:1317-1321.
30. Hartka E, Johnstone B, Leino EV, Motoyoshi M, Temple MT, Fillmore KM. The collaborative alcohol-related longitudinal project: a meta-analysis of depressive symptomatology and alcohol consumption over time. Br J Addict. 1991; 86:1283-1298.
31. Powell J. Dawe S, Richards D, Gossop M, Marks I, Strang J, Gray J. Can opiate addicts tell us about their relapse risk? Subjective predictors of clinical prognosis. Addict Behav. 1993;18:473-490.
32. Svrakic DM, Przybeck TR, Cloninger CR. Mood states and personality traits. J Affective Disord. 1992;24:217-226.