Action of progesterone and progesterone metabolites in menstrual-cycle- related disorders

Headache

Volumn 48, Issue SUPPL. 2, 2008, Pages

  Sundström Poromaa, Inger ^a  

^a UPPSALA UNIVERSITY   (Sweden)

Author keywords

aminobutyric acid receptor; Allopregnanolone; Premenstrual dysphoric disorder

Indexed keywords

3ALPHA HYDROXY 5ALPHA PREGNAN 20 ONE; 4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID A RECEPTOR; ALCOHOL; BARBITURIC ACID DERIVATIVE; BENZODIAZEPINE DERIVATIVE; CITALOPRAM; ELTANOLONE; LORAZEPAM; LUTEINIZING HORMONE; NEUROSTEROID; PROGESTERONE; SEROTONIN UPTAKE INHIBITOR;

ANOVULATION; ANTICONVULSANT ACTIVITY; ANXIETY; ARTICLE; COGNITION; DRUG TOLERANCE; FEMALE; HUMAN; IRRITABILITY; LUTEAL PHASE; METABOLITE; MOOD; NERVE CELL EXCITABILITY; NEUROMODULATION; NONHUMAN; PREMENSTRUAL DYSPHORIC DISORDER; PREMENSTRUAL SYNDROME; PRIORITY JOURNAL; PROGESTERONE BLOOD LEVEL; SACCADIC EYE MOVEMENT; SEDATION; STRESS; TRANQUILIZING ACTIVITY; WITHDRAWAL SYNDROME;

EID: 47249166165     PISSN: 00178748     EISSN: 15264610     Source Type: Journal    
DOI: 10.1111/j.1526-4610.2008.01201.x     Document Type: Article

References (45)

1. Speroff L, Fritz MA. Clinical Gynecologic Endocrinology and Infertility, 7th edn. Philadelphia, PA : Lippincott Williams & Wilkins 2005, 91 120.
2. Ottander U, Poromaa IS, Bjurulf E, Skytt A, Bäckström T, Olofsson JI. Allopregnanolone and pregnanolone are produced by the human corpus luteum. Mol Cell Endocrinol. 2005 239 : 37 44.
3. Stoffel-Wagner B. Neurosteroid biosynthesis in the human brain and its clinical implications. Ann N Y Acad Sci. 2003 1007 : 64 78.
4. Norberg L, Wahlstrom G, Bäckström T. The anaesthetic potency of 3 alpha-hydroxy-5 alpha-pregnan-20-one and 3 alpha-hydroxy-5 beta-pregnan-20-one determined with an intravenous EEG-threshold method in male rats. Pharmacol Toxicol. 1987 61 : 42 47.
5. Johansson IM, Birzniece V, Lindblad C, Olsson T, Bäckström T. Allopregnanolone inhibits learning in the Morris water maze. Brain Res. 2002 934 : 125 131.
6. Sveinsdottir H, Bäckström T. Menstrual cycle symptom variation in a community sample of women using and not using oral contraceptives. Acta Obstet Gynecol Scand. 2000 79 : 757 764.
7. Timby E, Balgard M, Nyberg S, et al. Pharmacokinetic and behavioral effects of allopregnanolone in healthy women. Psychopharmacology (Berl). 2006 186 : 414 424.
8. Luisi S, Petraglia F, Benedetto C, et al. Serum allopregnanolone levels in pregnant women: Changes during pregnancy, at delivery, and in hypertensive patients. J Clin Endocrinol Metab. 2000 85 : 2429 2433.
9. Purdy RH, Morrow AL, Moore PH Jr., Paul SM. Stress-induced elevations of gamma-aminobutyric acid type A receptor-active steroids in the rat brain. Proc Natl Acad Sci USA. 1991 88 : 4553 4557.
10. Concas A, Mostallino MC, Perra C, et al. Functional correlation between allopregnanolone and [35S]-TBPS binding in the brain of rats exposed to isoniazid, pentylenetetrazol or stress. Br J Pharmacol. 1996 118 : 839 846.
11. Campbell EM, Peterkin D, O'Grady K, Sanson-Fisher R. Premenstrual symptoms in general practice patients. Prevalence and treatment. J Reprod Med. 1997 42 : 637 646.
12. Woods NF, Most A, Dery GK. Prevalence of perimenstrual symptoms. Am J Public Health. 1982 72 : 1257 1264.
13. Ramcharan S, Love EJ, Fick GH, Goldfien A. The epidemiology of premenstrual symptoms in a population-based sample of 2650 urban women: Attributable risk and risk factors. J Clin Epidemiol. 1992 45 : 377 392.
14. Cohen LS, Soares CN, Otto MW, Sweeney BH, Liberman RF, Harlow BL. Prevalence and predictors of premenstrual dysphoric disorder (PMDD) in older premenopausal women. The Harvard Study of Moods and Cycles. J Affect Disord. 2002 70 : 125 132.
15. Gehlert S, Hartlage S. A design for studying the DSM-IV research criteria of premenstrual dysphoric disorder. J Psychosom Obstet Gynaecol. 1997 18 : 36 44.
16. Johnson SR, McChesney C, Bean JA. Epidemiology of premenstrual symptoms in a nonclinical sample. I. Prevalence, natural history and help-seeking behavior. J Reprod Med. 1988 33 : 340 346.
17. Rivera-Tovar AD, Frank E. Late luteal phase dysphoric disorder in young women. Am J Psychiatry. 1990 147 : 1634 1636.
18. Wittchen HU, Becker E, Lieb R, Krause P. Prevalence, incidence and stability of premenstrual dysphoric disorder in the community. Psychol Med. 2002 32 : 119 132.
19. Chawla A, Swindle R, Long S, Kennedy S, Sternfeld B. Premenstrual dysphoric disorder: Is there an economic burden of illness? Med Care. 2002 40 : 1101 1112.
20. Bäckström T, Andreen L, Birzniece V, et al. The role of hormones and hormonal treatments in premenstrual syndrome. CNS Drugs. 2003 17 : 325 342.
21. Hammarbäck S, Ekholm UB, Bäckström T. Spontaneous anovulation causing disappearance of cyclical symptoms in women with the premenstrual syndrome. Acta Endocrinol (Copenh). 1991 125 : 132 137.
22. Sundström I, Nyberg S, Bixo M, Hammarbäck S, Bäckström T. Treatment of premenstrual syndrome with gonadotropin-releasing hormone agonist in a low dose regimen. Acta Obstet Gynecol Scand. 1999 78 : 891 899.
23. Andréen L, Sundström-Poromaa I, Bixo M, Nyberg S, Bäckström T. Allopregnanolone concentration and mood - a bimodal association in postmenopausal women treated with oral progesterone. Psychopharmacology (Berl). 2006 187 : 209 221.
24. Schmidt PJ, Purdy RH, Moore PH Jr., Paul SM, Rubinow DR. Circulating levels of anxiolytic steroids in the luteal phase in women with premenstrual syndrome and in control subjects. J Clin Endocrinol Metab. 1994 79 : 1256 1260.
25. Sundström I, Andersson A, Nyberg S, Ashbrook D, Purdy RH, Bäckström T. Patients with premenstrual syndrome have a different sensitivity to a neuroactive steroid during the menstrual cycle compared to control subjects. Neuroendocrinology. 1998 67 : 126 138.
26. Sundström I, Bäckström T. Patients with premenstrual syndrome have decreased saccadic eye velocity compared to control subjects. Biol Psychiatry. 1998 44 : 755 764.
27. Wang M, Seippel L, Purdy RH, Bäckström T. Relationship between symptom severity and steroid variation in women with premenstrual syndrome: Study on serum pregnenolone, pregnenolone sulfate, 5 alpha-pregnane-3,20-dione and 3 alpha-hydroxy-5 alpha-pregnan-20-one. J Clin Endocrinol Metab. 1996 81 : 1076 1082.
28. Monteleone P, Luisi S, Tonetti A, et al. Allopregnanolone concentrations and premenstrual syndrome. Eur J Endocrinol. 2000 142 : 269 273.
29. Rapkin AJ, Morgan M, Goldman L, Brann DW, Simone D, Mahesh VB. Progesterone metabolite allopregnanolone in women with premenstrual syndrome. Obstet Gynecol. 1997 90 : 709 714.
30. Bicikova M, Putz Z, Hill M, et al. Serum levels of neurosteroid allopregnanolone in patients with premenstrual syndrome and patients after thyroidectomy. Endocr Regul. 1998 32 : 87 92.
31. Girdler SS, Straneva PA, Light KC, Pedersen CA, Morrow AL. Allopregnanolone levels and reactivity to mental stress in premenstrual dysphoric disorder. Biol Psychiatry. 2001 49 : 788 797.
32. A receptors, and escalated aggressive behavior. Horm Behav. 2003 44 : 242 257.
33. Beauchamp MH, Ormerod BK, Jhamandas K, Boegman RJ, Beninger RJ. Neurosteroids and reward: Allopregnanolone produces a conditioned place aversion in rats. Pharmacol Biochem Behav. 2000 67 : 29 35.
34. Bushman BJ. Effects of alcohol on human aggression. Validity of proposed explanations. Recent Dev Alcohol. 1997 13 : 227 243.
35. Kurthen M, Linke DB, Reuter BM, Hufnagel A, Elger CE. Severe negative emotional reactions in intracarotid sodium amytal procedures: Further evidence for hemispheric asymmetries? Cortex. 1991 27 : 333 337.
36. Lee GP, Loring DW, Meador KJ, Flanigin HF, Brooks BS. Severe behavioral complications following intracarotid sodium amobarbital injection: Implications for hemispheric asymmetry of emotion. Neurology. 1988 38 : 1233 1236.
37. Masia SL, Perrine K, Westbrook L, Alper K, Devinsky O. Emotional outbursts and post-traumatic stress disorder during intracarotid amobarbital procedure. Neurology. 2000 54 : 1691 1693.
38. Yoshimura H, Ogawa N. Acute and chronic effects of psychotropic drugs on maternal aggression in mice. Psychopharmacology (Berl). 1989 97 : 339 342.
39. Fish EW, Faccidomo S, DeBold JF, Miczek KA. Alcohol, allopregnanolone and aggression in mice. Psychopharmacology (Berl). 2001 153 : 473 483.
40. Gulinello M, Gong QH, Li X, Smith SS. Short-term exposure to a neuroactive steroid increases alpha4 GABA(A) receptor subunit levels in association with increased anxiety in the female rat. Brain Res. 2001 910 : 55 66.
41. Smith SS, Gong QH, Li X, et al. Withdrawal from 3alpha-OH-5alpha-pregnan- 20-one using a pseudopregnancy model alters the kinetics of hippocampal GABAA-gated current and increases the GABAA receptor alpha4 subunit in association with increased anxiety. J Neurosci. 1998 18 : 5275 5284.
42. Sundström I, Ashbrook D, Bäckström T. Reduced benzodiazepine sensitivity in patients with premenstrual syndrome: A pilot study. Psychoneuroendocrinology. 1997 22 : 25 38.
43. Nyberg S, Wahlstrom G, Bäckström T, Sundström Poromaa I. Altered sensitivity to alcohol in the late luteal phase among patients with premenstrual dysphoric disorder. Psychoneuroendocrinology. 2004 29 : 767 777.
44. Sundström I, Bäckström T. Citalopram increases pregnanolone sensitivity in patients with premenstrual syndrome: An open trial. Psychoneuroendocrinology. 1998 23 : 73 88.
45. Uzunov DP, Cooper TB, Costa E, Guidotti A. Fluoxetine-elicited changes in brain neurosteroid content measured by negative ion mass fragmentography. Proc Natl Acad Sci USA. 1996 93 : 12599 12604.