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Volumn 239, Issue 1-2, 2005, Pages 37-44

Allopregnanolone and pregnanolone are produced by the human corpus luteum

Author keywords

5 Reductase; Allopregnanolone; Cell culture; Human corpus luteum

Indexed keywords

3ALPHA HYDROXY 5ALPHA PREGNAN 20 ONE; 3ALPHA HYDROXYSTEROID DEHYDROGENASE; CHORIONIC GONADOTROPIN; ELTANOLONE; MESSENGER RNA; PROGESTERONE; STEROID 5ALPHA REDUCTASE; STEROID 5BETA REDUCTASE;

EID: 20544438243     PISSN: 03037207     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mce.2005.04.007     Document Type: Article
Times cited : (50)

References (37)
  • 1
    • 0020161392 scopus 로고
    • The conversion of progesterone into 5 alpha-pregnane-3,20-dione, 3 beta-hydroxy-5 alpha-pregnan-20-one, and its fatty acid esters by preparations of bovine corpora lutea
    • D.H. Albert, V.V. Prasad, and S. Lieberman The conversion of progesterone into 5 alpha-pregnane-3,20-dione, 3 beta-hydroxy-5 alpha-pregnan-20-one, and its fatty acid esters by preparations of bovine corpora lutea Endocrinology 111 1982 17 23
    • (1982) Endocrinology , vol.111 , pp. 17-23
    • Albert, D.H.1    Prasad, V.V.2    Lieberman, S.3
  • 4
    • 0025737587 scopus 로고
    • Neurosteroids: A new function in the brain
    • E.E. Baulieu Neurosteroids: a new function in the brain Biol. Cell 71 1991 3 10
    • (1991) Biol. Cell , vol.71 , pp. 3-10
    • Baulieu, E.E.1
  • 5
    • 0030991226 scopus 로고    scopus 로고
    • Expression cloning and characterization of oxidative 17beta- and 3alpha-hydroxysteroid dehydrogenases from rat and human prostate
    • M.G. Biswas, and D.W. Russell Expression cloning and characterization of oxidative 17beta- and 3alpha-hydroxysteroid dehydrogenases from rat and human prostate J. Biol. Chem. 272 1997 15959 15966
    • (1997) J. Biol. Chem. , vol.272 , pp. 15959-15966
    • Biswas, M.G.1    Russell, D.W.2
  • 7
    • 0032586969 scopus 로고    scopus 로고
    • Assignment of steroid 5beta-reductase (SRD5B1) and its pseudogene (SRD5BP1) to human chromosome bands 7q32 → q33 and 1q23 → q25, respectively, by in situ hybridization
    • A. Charbonneau, and V. Luu-The Assignment of steroid 5beta-reductase (SRD5B1) and its pseudogene (SRD5BP1) to human chromosome bands 7q32 → q33 and 1q23 → q25, respectively, by in situ hybridization Cytogenet. Cell. Genet. 84 1999 105 106
    • (1999) Cytogenet. Cell. Genet. , vol.84 , pp. 105-106
    • Charbonneau, A.1    Luu-The, V.2
  • 8
    • 0023681634 scopus 로고
    • Steroid modulation of the chloride ionophore in rat brain: Structure-activity requirements, regional dependance and mechanism of action
    • K.W. Gee, M.B. Bolger, R.E. Brinton, H. Coirini, and B.S. McEwen Steroid modulation of the chloride ionophore in rat brain: structure-activity requirements, regional dependance and mechanism of action J. Pharmacol. Exp. Ther. 246 1988 803 812
    • (1988) J. Pharmacol. Exp. Ther. , vol.246 , pp. 803-812
    • Gee, K.W.1    Bolger, M.B.2    Brinton, R.E.3    Coirini, H.4    McEwen, B.S.5
  • 10
    • 0345451657 scopus 로고    scopus 로고
    • Steroid metabolism in granulosa and theca interna cells from preovulatory follicles of domestic hen (Gallus domesticus)
    • Y. Gomez, P.N. Velazquez, M.A. Juarez-Oropeza, and E. Pedernera Steroid metabolism in granulosa and theca interna cells from preovulatory follicles of domestic hen (Gallus domesticus) Anim. Reprod. Sci. 52 1998 81 91
    • (1998) Anim. Reprod. Sci. , vol.52 , pp. 81-91
    • Gomez, Y.1    Velazquez, P.N.2    Juarez-Oropeza, M.A.3    Pedernera, E.4
  • 11
    • 0023774640 scopus 로고
    • Induced anovulation as treatment of premenstrual tension syndrome. a double-blind cross-over study with GnRH-agonist versus placebo
    • S. Hammarback, and T. Backstrom Induced anovulation as treatment of premenstrual tension syndrome. A double-blind cross-over study with GnRH-agonist versus placebo Acta. Obstet. Gynecol. Scand. 67 1988 159 166
    • (1988) Acta. Obstet. Gynecol. Scand. , vol.67 , pp. 159-166
    • Hammarback, S.1    Backstrom, T.2
  • 12
    • 0030255859 scopus 로고    scopus 로고
    • 5α-reductase 1 and 2 expression and activity in human ovarian follicles, stroma and corpus luteum as compared to neonatal foreskin
    • R.V. Haning, U. Tantravahi, Q. Zhao, R.J. Hackett, and J.A. Canick 5α-reductase 1 and 2 expression and activity in human ovarian follicles, stroma and corpus luteum as compared to neonatal foreskin J. Steroid. Biochem. Mol. Biol. 59 1996 199 204
    • (1996) J. Steroid. Biochem. Mol. Biol. , vol.59 , pp. 199-204
    • Haning, R.V.1    Tantravahi, U.2    Zhao, Q.3    Hackett, R.J.4    Canick, J.A.5
  • 13
    • 0027944742 scopus 로고
    • Progestin content and biosynthetic potential of the corpus luteum of the African elephant (Loxodonta africana)
    • J.K. Hodges, R.J. van Aarde, M. Heistermann, and H.O. Hoppen Progestin content and biosynthetic potential of the corpus luteum of the African elephant (Loxodonta africana) Reprod. Fertil. 102 1994 163 168
    • (1994) Reprod. Fertil. , vol.102 , pp. 163-168
    • Hodges, J.K.1    Van Aarde, R.J.2    Heistermann, M.3    Hoppen, H.O.4
  • 14
    • 0031045044 scopus 로고    scopus 로고
    • Concentrations of progesterone and the 5a-reduced progestins, 5a-pregnane-3,20-dione and 3a-hydroxy-5a-pregnan-20-one, in luteal tissue and circulating blood and their relationship to luteal function in the African elephant (Loxodonta africana)
    • J.K. Hodges, M. Heistermann, A. Beard, and R.J. van Aarde Concentrations of progesterone and the 5a-reduced progestins, 5a-pregnane-3,20-dione and 3a-hydroxy-5a-pregnan-20-one, in luteal tissue and circulating blood and their relationship to luteal function in the African elephant (Loxodonta africana) Biol. Reprod. 56 1997 640 646
    • (1997) Biol. Reprod. , vol.56 , pp. 640-646
    • Hodges, J.K.1    Heistermann, M.2    Beard, A.3    Van Aarde, R.J.4
  • 15
    • 0026326528 scopus 로고
    • Characterization and chromosomal mapping of a human steroid 5 alpha-reductase gene and pseudogene and mapping of the mouse homologue
    • E.P. Jenkins, C.L. Hsieh, A. Milatovich, K. Normington, D.M. Berman, U. Francke, and D.W. Russel Characterization and chromosomal mapping of a human steroid 5 alpha-reductase gene and pseudogene and mapping of the mouse homologue Genomics 11 1991 1102 1112
    • (1991) Genomics , vol.11 , pp. 1102-1112
    • Jenkins, E.P.1    Hsieh, C.L.2    Milatovich, A.3    Normington, K.4    Berman, D.M.5    Francke, U.6    Russel, D.W.7
  • 16
    • 0027979898 scopus 로고
    • Cloning and expression of cDNA of human delta 4-3-oxosteroid 5β-reductase and substrate specificity of the expressed enzyme
    • H. Kondo, M.H. Kai, Y. Setoguchi, G. Eggertsen, P. Sjöblom, T. Setoguchi, K.I. Okuda, and I. Björkhem Cloning and expression of cDNA of human delta 4-3-oxosteroid 5β-reductase and substrate specificity of the expressed enzyme Eur. J. Biochem. 219 1994 357 363
    • (1994) Eur. J. Biochem. , vol.219 , pp. 357-363
    • Kondo, H.1    Kai, M.H.2    Setoguchi, Y.3    Eggertsen, G.4    Sjöblom, P.5    Setoguchi, T.6    Okuda, K.I.7    Björkhem, I.8
  • 17
    • 0029895224 scopus 로고    scopus 로고
    • Allopregnanolone (THP) mediates anesthetic effects of progesterone in rat brain
    • A. Korneyev, and E. Costa Allopregnanolone (THP) mediates anesthetic effects of progesterone in rat brain Horm. Behav. 30 1996 37 43
    • (1996) Horm. Behav. , vol.30 , pp. 37-43
    • Korneyev, A.1    Costa, E.2
  • 19
    • 0031963930 scopus 로고    scopus 로고
    • Interaction between 3α-hydroxy-5β-pregnan-20-one and carbachol in the control of neuronal excitability in hippocampal slices of female rats in defined phases of the oestrus
    • S. Landgren, M.D. Wang, T. Bäckström, and S. Johansson Interaction between 3α-hydroxy-5β-pregnan-20-one and carbachol in the control of neuronal excitability in hippocampal slices of female rats in defined phases of the oestrus Acta Physiol. Scand. 162 1998 77 88
    • (1998) Acta Physiol. Scand. , vol.162 , pp. 77-88
    • Landgren, S.1    Wang, M.D.2    Bäckström, T.3    Johansson, S.4
  • 20
    • 0017105941 scopus 로고
    • Identification of two 5α-reduced pregnanes as major metabolites of progesterone in immature rat ovaries (1000 g supernatant) in vitro
    • N. Lerner, and B. Eckstein Identification of two 5α-reduced pregnanes as major metabolites of progesterone in immature rat ovaries (1000 g supernatant) in vitro Endocrinology 98 1976 179 188
    • (1976) Endocrinology , vol.98 , pp. 179-188
    • Lerner, N.1    Eckstein, B.2
  • 21
    • 0022483382 scopus 로고
    • Steroid hormone metabolites are barbiturate-like modulators of the GABA receptor
    • M.D. Majewska, N.L. Harrison, R.D. Schwartz, J.L. Barker, and S.M. Paul Steroid hormone metabolites are barbiturate-like modulators of the GABA receptor Science 232 1986 1004 1007
    • (1986) Science , vol.232 , pp. 1004-1007
    • Majewska, M.D.1    Harrison, N.L.2    Schwartz, R.D.3    Barker, J.L.4    Paul, S.M.5
  • 22
    • 0026032108 scopus 로고
    • Non-genomic and genomic effects of steroids on neural activity
    • B.S. McEwen Non-genomic and genomic effects of steroids on neural activity Trends Pharmacol. Sci. 12 1991 141 147
    • (1991) Trends Pharmacol. Sci. , vol.12 , pp. 141-147
    • McEwen, B.S.1
  • 23
    • 0032952615 scopus 로고    scopus 로고
    • Functional evidence for divergent receptor activation mechanisms of luteotropic and luteolytic events in the human corpus luteum
    • U. Ottander, C. Leung, and J.I. Olofsson Functional evidence for divergent receptor activation mechanisms of luteotropic and luteolytic events in the human corpus luteum Mol. Hum. Reprod. 5 1999 391 395
    • (1999) Mol. Hum. Reprod. , vol.5 , pp. 391-395
    • Ottander, U.1    Leung, C.2    Olofsson, J.I.3
  • 24
    • 0033998156 scopus 로고    scopus 로고
    • A putative stimulatory role of progesterone acting via progesterone receptors in the steroidogenic cells of the human corpus luteum
    • U. Ottander, K. Hosokawa, K. Liu, A. Bergh, T. Ny, and J.I. Olofsson A putative stimulatory role of progesterone acting via progesterone receptors in the steroidogenic cells of the human corpus luteum Biol. Reprod. 62 2000 655 663
    • (2000) Biol. Reprod. , vol.62 , pp. 655-663
    • Ottander, U.1    Hosokawa, K.2    Liu, K.3    Bergh, A.4    Ny, T.5    Olofsson, J.I.6
  • 25
    • 0025882098 scopus 로고
    • Stress-induced elevations of gamma-aminobutyric acid type a receptor-active steroids in the rat brain
    • R. Purdy, A. Morrow, P. Moore, and S. Paul Stress-induced elevations of gamma-aminobutyric acid type A receptor-active steroids in the rat brain Proc. Natl. Acad. Sci. U.S.A. 88 1991 4553 4557
    • (1991) Proc. Natl. Acad. Sci. U.S.A. , vol.88 , pp. 4553-4557
    • Purdy, R.1    Morrow, A.2    Moore, P.3    Paul, S.4
  • 26
  • 28
    • 0032922384 scopus 로고    scopus 로고
    • Neuropsychopharmacological properties of neuroactive steroids
    • R. Rupprecht, and F. Holsboer Neuropsychopharmacological properties of neuroactive steroids Steroids 64 1999 83 91
    • (1999) Steroids , vol.64 , pp. 83-91
    • Rupprecht, R.1    Holsboer, F.2
  • 29
    • 0028037297 scopus 로고
    • Circulating levels of anxiolytic steroids in the luteal phase in women with premenstrual syndrome and in control subjects
    • P. Schmidt, R. Purdy, P. Moore Jr., S. Paul, and D. Rubinow Circulating levels of anxiolytic steroids in the luteal phase in women with premenstrual syndrome and in control subjects J. Clin. Endocrinol. Metab. 79 1994 1256 1260
    • (1994) J. Clin. Endocrinol. Metab. , vol.79 , pp. 1256-1260
    • Schmidt, P.1    Purdy, R.2    Moore Jr., P.3    Paul, S.4    Rubinow, D.5
  • 30
    • 0034872874 scopus 로고    scopus 로고
    • Neuroactive steroid plasma levels in patients with generalized anxiety disorder
    • T. Semeniuk, J.S. Ghandri, and J-M. LeMelledo Neuroactive steroid plasma levels in patients with generalized anxiety disorder J. Neuropsychiatr. Clin. 13 2001 396 398
    • (2001) J. Neuropsychiatr. Clin. , vol.13 , pp. 396-398
    • Semeniuk, T.1    Ghandri, J.S.2    Lemelledo, J.-M.3
  • 31
    • 0035206892 scopus 로고    scopus 로고
    • Neurosteroid metabolism in the human brain
    • B. Stoffel-Wagner Neurosteroid metabolism in the human brain Eur. J. Endocrinol. 145 2001 669 679
    • (2001) Eur. J. Endocrinol. , vol.145 , pp. 669-679
    • Stoffel-Wagner, B.1
  • 32
    • 17044444204 scopus 로고    scopus 로고
    • Concentrations of 3[alpha]-reduced neuroactive steroids and their precursors in plasma of patients with major depression and after clinical recovery
    • A. Strohle, E. Romeo, B. Hermann, A. Pasini, G. Spalletta, F. di Michele, F. Holsboer, and R. Rupprecht Concentrations of 3[alpha]-reduced neuroactive steroids and their precursors in plasma of patients with major depression and after clinical recovery Biol. Psychiatr. 45 1999 274 277
    • (1999) Biol. Psychiatr. , vol.45 , pp. 274-277
    • Strohle, A.1    Romeo, E.2    Hermann, B.3    Pasini, A.4    Spalletta, G.5    Di Michele, F.6    Holsboer, F.7    Rupprecht, R.8
  • 33
    • 0031962178 scopus 로고    scopus 로고
    • Patients with premenstrual syndrome have a different sensitivity to a neuroactive steroid during the menstrual cycle compared to control subjects
    • I. Sundström, A. Andersson, S. Nyberg, D. Ashbrook, R. Purdy, and T. Bäckström Patients with premenstrual syndrome have a different sensitivity to a neuroactive steroid during the menstrual cycle compared to control subjects Neuroendocrinology 67 1998 126 138
    • (1998) Neuroendocrinology , vol.67 , pp. 126-138
    • Sundström, I.1    Andersson, A.2    Nyberg, S.3    Ashbrook, D.4    Purdy, R.5    Bäckström, T.6
  • 34
    • 0028808886 scopus 로고
    • Cyclic change in 3α-hydroxysteroid dehydrogenase in rat ovary during the estrous cycle
    • M. Takahashi, N. Iwata, S. Hara, T. Mukai, M. Takayama, and T. Endo Cyclic change in 3α-hydroxysteroid dehydrogenase in rat ovary during the estrous cycle Biol. Reprod. 53 1995 1265 1270
    • (1995) Biol. Reprod. , vol.53 , pp. 1265-1270
    • Takahashi, M.1    Iwata, N.2    Hara, S.3    Mukai, T.4    Takayama, M.5    Endo, T.6
  • 35
    • 0034544581 scopus 로고    scopus 로고
    • Quantification of neurosteroids in rat plasma and brain following swim stress and allopregnanolone administration using negative chemical ionization gas chromatography/mass spectrometry
    • M. Vallee, J.D. Rivera, G.F. Koob, R.H. Purdy, and R.L. Fitzgerald Quantification of neurosteroids in rat plasma and brain following swim stress and allopregnanolone administration using negative chemical ionization gas chromatography/mass spectrometry Anal. Biochem. 287 2000 153 166
    • (2000) Anal. Biochem. , vol.287 , pp. 153-166
    • Vallee, M.1    Rivera, J.D.2    Koob, G.F.3    Purdy, R.H.4    Fitzgerald, R.L.5
  • 36
    • 0029961691 scopus 로고    scopus 로고
    • Relationship between symptom severity and steroid variation in women with premenstrual syndrome: Study on serum pregnenolone, pregnenolone sulfate, 5α-pregnane-3,20-dione and 3α-hydroxy-5α- pregnan-20-one
    • M. Wang, L. Seippel, R.H. Purdy, and T. Bäckström Relationship between symptom severity and steroid variation in women with premenstrual syndrome: study on serum pregnenolone, pregnenolone sulfate, 5α-pregnane-3,20-dione and 3α-hydroxy-5α- pregnan-20-one J. Clin. Endocrinol. Metab. 81 1996 1076 1082
    • (1996) J. Clin. Endocrinol. Metab. , vol.81 , pp. 1076-1082
    • Wang, M.1    Seippel, L.2    Purdy, R.H.3    Bäckström, T.4
  • 37
    • 0025987983 scopus 로고
    • Anxiolytic activity of the progesterone metabolite 3α-OH, 5α-pregnan-3α-ol-one
    • S. Wieland, C. Lan, S. Mirasedeghi, and K. Gee Anxiolytic activity of the progesterone metabolite 3α-OH, 5α-pregnan-3α-ol-one Brain Res. 565 1991 263 268
    • (1991) Brain Res. , vol.565 , pp. 263-268
    • Wieland, S.1    Lan, C.2    Mirasedeghi, S.3    Gee, K.4


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