Slowed release of thrombin-cleaved factor VIII from von Willebrand factor by a monoclonal and a human antibody is a novel mechanism for factor VIII inhibition

Journal of Biological Chemistry

Volumn 271, Issue 44, 1996, Pages 27424-27431

  Saenko, Evgueni L ^a   Shima, Midori ^b   Gilbert, Gary E ^c,d   Scandella, Dorothea ^a,d  

^a HOLLAND LABORATORY   (United States)

^b NARA MEDICAL UNIVERSITY   (Japan)

^c BRIGHAM AND WOMEN S HOSPITAL   (United States)

^d AMERICAN RED CROSS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD CLOTTING FACTOR 8; EPITOPE; MONOCLONAL ANTIBODY; THROMBIN; VON WILLEBRAND FACTOR;

ARTICLE; BINDING AFFINITY; BINDING SITE; CONTROLLED STUDY; MATHEMATICAL MODEL; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; RADIOIMMUNOASSAY;

ANTIBODIES, MONOCLONAL; ANTIBODY AFFINITY; ENZYME ACTIVATION; FACTOR VIII; HEMOPHILIA A; HUMANS; IMMUNOGLOBULIN G; KINETICS; MACROMOLECULAR SUBSTANCES; MODELS, THEORETICAL; THROMBIN; VON WILLEBRAND FACTOR;

EID: 0029861521     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.271.44.27424     Document Type: Article

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