An orbitofrontostriatopallidal pathway for morality: Evidence from postlesion antisocial and obsessive-compulsive disorder

Cognitive Neuropsychiatry

Volumn 13, Issue 4, 2008, Pages 296-337

  Braun, Claude M J ^a   Léveillé, Cathy ^a   Guimond, Anik ^a  

^a UNIVERSITÉ DU QUÉBEC À MONTRÉAL   (Canada)

Author keywords

Antisocial; Compulsive; Globus pallidus; Hypermoralism; Hypomoralism; Moralism; Morality; Obsessive; Orbitofrontal

Indexed keywords

ALPHA ADRENERGIC RECEPTOR STIMULATING AGENT; DOPAMINE; METHYLPHENIDATE; NEUROTRANSMITTER; SEROTONIN; SEROTONIN UPTAKE INHIBITOR;

ADOLESCENT; ADULT; AGED; ANTISOCIAL BEHAVIOR; ARTICLE; BRAIN DAMAGE; BRAIN FUNCTION; BRAIN MAPPING; BRAIN REGION; CHILD; CORPUS STRIATUM; EMPIRICAL RESEARCH; FEMALE; FRONTAL CORTEX; GLOBUS PALLIDUS; HUMAN; MAJOR CLINICAL STUDY; MALE; MORALITY; MULTIVARIATE ANALYSIS; NERVOUS SYSTEM; NEUROBIOLOGY; OBSESSIVE COMPULSIVE DISORDER; ORBITAL CORTEX; ORBITOFRONTOSTRIATOPALLIDAL PATHWAY; PRIORITY JOURNAL; PUTAMEN;

ADOLESCENT; ADULT; AGE OF ONSET; AGED; ANTISOCIAL PERSONALITY DISORDER; BRAIN MAPPING; CHILD; CHILD, PRESCHOOL; CORPUS STRIATUM; DOMINANCE, CEREBRAL; DOPAMINE; FEMALE; FRONTAL LOBE; GLOBUS PALLIDUS; HUMANS; INFANT; MALE; MIDDLE AGED; MORALS; NEURAL PATHWAYS; OBSESSIVE-COMPULSIVE DISORDER; SEROTONIN;

EID: 47249151803     PISSN: 13546805     EISSN: 14640619     Source Type: Journal    
DOI: 10.1080/13546800802088580     Document Type: Article

References (202)

1. Abramowitz, J. S. (2001). Treatment of scrupulous obsessions and compulsions using exposure and response prevention: A case report. Cognitive and Behavioral Practice, 8, 79-85.
2. Abramowitz, J. S., Whiteside, S., Lynam, D., & Kalsy, S. (2003). Is thought-action fusion specific to obsessive-compulsive disorder? A mediating role of negative affect. Behavioral Research and Therapy, 41, 1069-1079.
3. Ackerly, S. S., & Benton, A. L. (1948). Report of a case of bilateral frontal lobe defect. Research Publications: Associations for Research in Nervous and Mental Diseases, 27, 479-504.
4. Adams, K. H., Hansen, E. S., Pinborg, L. H., Hasselbalch, S. G., Svarer, C., Holm, S., et al. (2005). Patients with obsessive-compulsive disorder have increased 5-HT2A receptor binding in the caudate nuclei. International Journal of Neuropsychopharmacology, 8, 391-401.
5. Aksaray, G., Yelken, B., Kaptanoglu, C., Oflu, S., & Ozaltin, M. (2001). Sexuality in women with obsessive compulsive disorder. Journal of Sex and Marital Therapy, 27, 273-277.
6. Alexander, G. E., DeLong, M. R., & Strick, P. L. (1986). Parallel organization of functionally segregated circuits linking basal ganglia and cortex. Annual Review of Neuroscience, 9, 357-381.
7. Allen, J. J., & Tune, G. S. (1975). Lynfield obsessional/compulsive questionnaire. Scottish Medical Journal, 20, 21-31.
8. American Psychiatric Association. (1994). Diagnostic and statistical manual of mental disorders (4th ed.). Washington, DC: Author.
9. Ames, D., Cummings, J. L., Wirshing, W. C., Quinn, B., & Mahler, M. (1994). Repetitive and compulsive behavior in frontal lobe degenerations. Journal of Neuropsychiatry and Clinical Neurosciences, 6, 100-113.
10. Amir, N., Freshman, M., Ramsey, B., Neary, E., & Brigidi, B. (2001). Thought-action fusion in individuals with OCD symptoms. Behavior Research and Therapy, 39, 765-776.
11. Anderson, S. W., Bechara, A., Damasio, H., Tranel, D., & Damasio, R. (1999). Impairment of social and moral behavior related to early damage in human prefrontal cortex. Nature Neuroscience, 2, 1032-1037.
12. Arnett, P. A. (1997). Autonomic responsivity in psychopaths: A critical review and theoretical proposal. Clinical Psychology Review, 17, 903-936.
13. Aromäki, A., Lindman, R. E., & Eriksson, C. J. P. (1999). Testosterone, aggressiveness, and antisocial personality. Aggressive Behavior, 25, 113-123.
14. Baier, C. J., & Wright, B. R. E. (2001). If you love me, keep my commandments: A meta-analysis of the effect of religion on crime. Journal of Research in Crime and Delinquency, 38, 3-21.
15. Baxter, L. R., Jr. (2003). Basal ganglia systems in ritualistic social displays: Reptiles and humans; function and illness. Physiology and Behavior, 79, 451-460.
16. Berle, D., & Starcevic, V. (2005). Thought-action fusion: Review of the literature and future directions. Clinical Psychology Review, 25, 263-284.
17. Bhattacharyya, S., Reddy, Y. C., & Khanna, S. (2005). Depressive and anxiety disorder comorbidity in obsessive compulsive disorder. Psychopathology, 38, 315-319.
18. Biglan, A., Metzler, C. W., Wirt, R., Ary, D., Noell, J., Ochs, L., et al. (1990). Social and behavioral factors associated with high-risk sexual behavior among adolescents. Journal of Behavioral Medicine, 13, 245-261.
19. Bilgic, B., Baral-Kulaksizoglu, I., Hanagasi, H., Saylan, M., Aykutlu, E., Gurvit, H., & Emre, M. (2004). Obsessive-compulsive disorder secondary to bilateral frontal damage due to a closed head injury. Cognitive and Behavioral Neurology, 17, 118-120.
20. Blair, R. J. R. (1997). Moral reasoning and the child with psychopathic tendencies. Personality and Individual Differences, 22, 731-739.
21. Blair, R. J. R., & Cipolotti, L. (2000). Impaired social response reversal: A case of 'acquired sociopathy'. Brain, 123, 1122-1141.
22. Blair, R. J. R., Monson, J., & Frederickson, N. (2001). Moral reasoning and conduct problems in children with emotional and behavioural difficulties. Personality and Individual Differences, 31, 799-811.
23. Blustein, J., & Seeman, M. V. (1972). Brain tumors presenting as functional psychiatric disturbances. Canadian Psychiatric Association Journal, 17, 59-63.
24. Borg, J. S., Hynes, C., van Horn, J., Grafton, S., & Sinnott-Armstrong, W. (2006). Consequences, action, and intention as factors in moral judgments: An FMRI investigation. Journal of Cognitive Neuroscience, 18, 803-817.
25. Braun, C. M. J., Montour-Proulx, I., Daigneault, S., Rouleau, I., Kuehn, I., Piskopos, M., et al. (2002). Intellectual outcome of unilateral focal cortical brain damage as a function of age, gender and etiology. Behavioral Neurology, 12, 1-12.
26. Buck, R. (1999). The biological affects: A typology. Psychological Review, 106, 301-336.
27. Burns, J. M., & Swerdlow, R. H. (2003). Right orbitofrontal tumor with pedophilia symptom and constructional apraxia sign. Archives of Neurology, 60, 437-440.
28. Campbell, M. A., Porter, S., & Santor, D. (2004). Psychopathic traits in adolescent offenders: An evaluation of criminal history, clinical, and psychosocial correlates. Behavioral Science and Law, 22, 23-47.
29. Carmin, C. N., Wiegartz, P. S., Yunus, U., & Gillock, K. L. (2002). Treatment of late-onset OCD following basal ganglia infarct. Depression and Anxiety, 15, 87-90.
30. Catapano, F., Monteleone, P., Fuschino, A., Maj, M., & Kemali, D. (1992). Melatonin and cortisol secretion in patients with primary obsessive-compulsive disorder. Psychiatry Research, 44, 217-225.
31. Chacko, R. C., Corbin, M. A., & Harper, R. G. (2000). Acquired obsessive-compulsive disorder associated with basal ganglia lesions. Journal of Neuropsychiatry and Clinical Neuroscience, 12, 269-272.
32. Cheng, D., Hong, C. J., Liao, D. L., & Tsai, S. J. (2006). Association study of androgen receptor CAG repeat polymorphism and male violent criminal activity. Psychoneuroendocrinology, 31, 548-552.
33. Cleckley, H. (1976). The mask of sanity. St Louis, MO: Mosby. (Original work published 1941)
34. Coles, M. E., Frost, R. O., Heimberg, R. G., & Rhe aume, J. (2003). "Not just right experiences": Perfectionism, obsessive-compulsive features and general psychopathology. Behaviour Research and Therapy, 41, 681-700.
35. Coles, M. E., Mennin, D. S., & Heimberg, R. G. (2001). Distinguishing obsessive features and worries: The role of thought-action fusion. Behavior Research and Therapy, 39, 947-959.
36. Comunian, A. L., & Gielen, U. P. (1995). Moral reasoning and prosocial action in Italian culture. Journal of Social Psychology, 135, 699-706.
37. Cooke, D. J., & Michie, C. (2001). Refining the construct of psychopathy: Towards a hierarchical model. Psychological Assessment, 13, 171-188.
38. Cosgrove, G. R., & Rauch, S. L. (1995). Psychosurgery. Neurosurgical Clinics of North America, 6, 167-176.
39. Croisile, B., Tourniaire, D., Confavreux, Trillet, M., & Aimard, G. (1989). Bilateral damage to the head of the caudate nuclei. Annals of Neurology, 25, 313-314.
40. Daniele, A., Bartolomeo, P., Cassetta, E., Bentivoglio, A. R., Gainotti, G., & Albanese, A. (1997). Obsessive-compulsive behaviour and cognitive impairment in a Parkinsonian patient after left putaminal lesion. Journal of Neurology, Neurosurgery and Psychiatry, 62, 288-302.
41. Darke, S., Hall, W., & Swift, W. (1994). Prevalence, symptoms and correlates of antisocial personality disorder among methadone maintenance clients. Drug and Alcohol Dependence, 34, 253-257.
42. De Almeida, R. M., Ferrari, P. F., Parmigiani, S., & Miczek, K. A. (2005). Escalated aggressive behavior: Dopamine, serotonin and GABA. European Journal of Pharmacology, 526, 51-64.
43. DeGue, S., & DiLillo, D. (2004). Understanding perpetrators of nonphysical sexual coercion: Characteristics of those who cross the line. Violence and Victims, 19, 673-688.
44. Demirkol, A., Erdem, H., Inan, L., Yigit, A., & Guney, M. (1999). Bilateral globus pallidus lesions in a patient with Tourette syndrome and related disorders. Biological Psychiatry, 46, 863-867.
45. Denys, D., van der Wee, N., Janssen, J., de Geus, F., & Westenberg, H. G. (2004a). Low level of dopaminergic D2 receptor binding in obsessive-compulsive disorder. Biological Psychiatry, 55, 1041-1045.
46. Denys, D., van Nieuwerburgh, F., Deforce, D., & Westenberg, H. (2006). Association between the dopamine D2 receptor TaqI A2 allele and low activity COMT allele with obsessive-compulsive disorder in males. European Neuropsychopharmacology, 16, 446-450.
47. Denys, D., Zohar, J., & Westenberg, H. G. M. (2004b). The role of dopamine in obssessive-compulsive disorder: Preclinical and clinical evidence. Journal of Clinical Psychiatry, 65(Suppl. 14), 11-17.
48. Destee, A., Gray, F., Parent, M., Neuville, V., Muller, J. P., Verier, A., & Warot, P. (1990). Comportement compulsif d'allure obsessionnelle et paralysie supranucle aire progressive [Obsessive-compulsive behavior and progressive supranuclear palsy]. Revue Neurologique, 146, 12-18.
49. Dimitrov, M., Phipps, M., Zahn, T. P., & Grafman, J. (1999). A thoroughly modern Gage. Neurocase, 5, 345-354.
50. Eblen, F., & Graybiel, A. M. (1995). Highly restricted origin of prefrontal cortical inputs to striosomes in the macaque monkey. Journal of Neuroscience, 15, 5999-6013.
51. Eisenberg, N., Guthrie, I. K., Cumberland, A., Murphy, B. C., Shepard, S. A., Zhou, Q., & Carlo, G. (2002). Prosocial development in early adulthood: A longitudinal study. Journal of Personality and Social Psychology, 82, 993-1006.
52. Emmelkamp, P. M. G., & Aardema, A. (1999). Metacognition, specific obsessive-compulsive beliefs and obsessive-compulsive behaviour. Clinical Psychology and Psychotherapy, 6, 139-145.
53. Enoch, M. A., Greenberg, B. D., Murphy, D. L., & Goldman, D. (2001). Sexually dimorphic relationship of a 5-HT2A promoter polymorphism with obsessive-compulsive disorder. Biological Psychiatry, 49, 385-388.
54. Eslinger, P. J., & Damasio, A. R. (1985). Severe disturbance of higher cognition after bilateral frontal lobe ablation: Patient EVR. Neurology, 35, 1731-1741.
55. Eslinger, P. J., Grattan, L. M., Damasio, H., & Damasio, A. R. (1992). Developmental consequences of childhood frontal lobe damage. Archives of Neurology, 49, 764-769.
56. Evans, D. W., Lewis, M. D., & Iobst, E. (2004). The role of the orbitofrontal cortex in normally developing compulsive-like behaviors and obsessive-compulsive disorder. Brain and Cognition, 55, 220-234.
57. Fallon, B. A., Liebowitz, M. R., Hollander, E., Schneier, F. R., Campeas, R. B., Fairbanks, J., et al. (1990). The pharmacotherapy of moral or religious scrupulosity. Journal of Clinical Psychiatry, 51, 517-521.
58. Ferry, A. T., Lu, X. C., & Price, J. L. (2000). Effects of excitotoxic lesions in the ventral striatopallidal - thalamocortical pathway on odor reversal learning: Inability to extinguish an incorrect response. Experimental Brain Research, 131, 320-335.
59. Fineberg, N. A., & Gale, T. M. (2005). Evidence-based pharmacotherapy of obsessive-compulsive disorder. International Journal of Neuropsychopharmacology, 8, 107-129.
60. Foa, E. B., Sacks, M. B., Tolin, D. F., Prezworski, A., & Amir, N. (2002). Inflated perception of responsibility for harm in OCD patients with and without checking compulsions: A replication and extension. Journal of Anxiety Disorders, 16, 443-453.
61. Fossati, A., Barratt, E. S., Carretta, I., Leonardi, B., Grazioli, F., & Maffei, C. (2004). Predicting borderline and antisocial personality disorder features in nonclinical subjects using measures of impulsivity and aggressiveness. Psychiatry Research, 125, 161-170.
62. Friedlander, L., & Desrocher, M. (2006). Neuroimaging studies of obsessive-compulsive disorder in adults and children. Clinical Psychology Review, 26, 32-49.
63. Frost, R. O., & Steketee, G. (1997). Perfectionism in obsessive-compulsive disorder patients. Behavior Research and Therapy, 35, 291-296.
64. Fullana, M. A., Mataix-Cols, D., Caseras, X., Alonso, P., Manuel Menchon, J., Vallejo, J., & Torrubia, R. (2004). High sensitivity to punishment and low impulsivity in obsessivecompulsive patients with hoarding symptoms. Psychiatry Research, 129, 21-27.
65. Gamazo-Garran, P., Soutullo, C. A., & Ortuno, F. (2002). Obsessive-compulsive disorder secondary to brain dysgerminoma in an adolescent boy: A positron emission tomography case report. Journal of Child and Adolescent Psychopharmacology, 12, 259-263.
66. Gehris, T. L., Kathol, R. G., Black, D. W., & Noyes, R. (1990). Urinary free cortisol levels in obsessive-compulsive disorder. Psychiatry Research, 32, 151-158.
67. Geller, D. A. (2006). Obsessive-compulsive and spectrum disorders in children and adolescents. Psychiatric Clinics of North America, 29, 353-370.
68. Gerra, G., Zaimovic, A., Moi, G., Bussandri, M., Bubici, C., Mossini, M., et al. (2004). Aggressive responding in abstinent heroin addicts: Neuroendocrine and personality correlates. Progress in Neuropsychopharmacology and Biological Psychiatry, 28, 129-139.
69. Ghassemzadeh, H., Bolhari, J., Birashk, B., & Salavati, M. (2005). Responsibility attitude in a sample of Iranian obsessive-compulsive patients. International Journal of Social Psychiatry, 51, 13-22.
70. Giedd, J. N., Rapoport, J. L., Leonard, H. L., Richter, D., & Swedo, S. E. (1996). Case study: Acute basal ganglia enlargement and obsessive-compulsive symptoms in an adolescent boy. Journal of the American Academy of Child and Adolescent Psychiatry, 35, 913-915.
71. Golden, C. J. (1984). Clinical implications of neuropsychological assessment of children. In R. W. Bell, J. Elias, R. L. Greene, & J. H. Harvey (Eds.), Developmental psychobiology and clinical neuropsychology (pp. 109-133). Lubbock, TX: Texas Tech Press.
72. Goodman, W. K., Price, L. H., Rasmussen, S. A., Mazure, C., Fleischmann, R. L., Hill, C. L., Heninger, G. R., & Charney, D. S. (1989a). The Yale-Brown Obsessive Compulsive Scale. I. Development, use, and reliability. Archives of General Psychiatry, 46, 1006-1011.
73. Goodman, W. K., Price, L. H., Rasmussen, S. A., Mazure, C., Delgado, P., Heninger, G. R., & Charney, D. S. (1989b). The Yale-Brown Obsessive Compulsive Scale. II. Validity. Archives of General Psychiatry, 46, 1012-1016.
74. Graybiel, A. M., & Kubota, Y. (2003). Understanding corticobasal networks as part of a habit formation system. In M. A. Bédard, Y. Agid, S. Chouinard, S. Fahn, A. D. Korczyn, & P. Lespérance (Eds.), Mental and behavioral dysfunction in movement disorders (pp. 51-59). Totowa, NJ: Humana Press.
75. Gretton, H. M., Hare, R. D., & Catchpole, R. E. (2004). Psychopathy and offending from adolescence to adulthood: A 10-year follow-up. Journal of Consulting and Clinical Psychology, 72, 636-645.
76. Gwilliam, P., Wells, A., & Cartwright-Hatton, S. (2004). Does meta-cognition or responsibility predict obsessive-compulsive symptoms: A test of the metacognitive model. Clinical Psychology and Psychotherapy, 11, 137-144.
77. Haber, S. N. (2003). Integrating cognition and motivation into the basal ganglia pathways of action. In M. A. Bédard, Y. Agid, S. Chouinard, S. Fahn, A. D. Korczyn, & P. Lespérance (Eds.), Mental and behavioral dysfunction in movement disorders (pp. 35-51). Totowa, NJ: Humana Press.
78. Haber, S. N., Kunishio, K., Mizobuchi, M., & Lynd-Balta, E. (1995). The orbital and medial prefrontal circuit through the primate basal ganglia. Journal of Neuroscience, 15, 4851-4867.
79. Hare, R. D. (1991). Manual for the Hare Psychopathy Checklist-Revised. Toronto, Canada: Multihealth Systems.
80. Harlow, J. M. (1868). Recovery from the passage of an iron bar through the head. Publications of the Massachussetts Medical Society, 2, 327-347.
81. Harry, B. (1992). Criminals' explanations of their criminal behavior, Part II: A possible role for psychopathy. Journal of Forensic Science, 37, 1334-1340.
82. Hemmings, S. M., Kinnear, C. J., Lochner, C., Niehaus, D. J., Knowles, J. A., Moolman-Smook, J. C., et al. (2004). Early- versus late-onset obsessive-compulsive disorder: Investigating genetic and clinical correlates. Psychiatry Research, 128, 175-182.
83. Hendler, T., Goshen, E., Tadmor, R., Lustig, M., Zwas, S. T., & Zohar, J. (1999). Evidence for striatal modulation in the presence of fixed cortical injury in obsessive-compulsive disorder (OCD). European Neuropsychopharmacology, 9, 371-376.
84. Hibbard, M. R., Bogdany, J., Uysal, S., Kepler, K., Silver, J. M., Gordon, W. A., & Haddad, L. (2000). Axis II psychopathology in individuals with traumatic brain injury. Brain Injury, 14, 45-61.
85. Hinshaw, S. P., Heller, T., & McHale, J. P. (1992). Covert antisocial behavior in boys with attention-deficit hyperactivity disorder: External validation and effects of methylphenidate. Journal of Consulting and Clinical Psychology, 60, 274-281.
86. Hirose, S. (2001). Effective treatment of aggression and impulsivity in antisocial personality disorder with risperidone. Psychiatry and Clinical Neurosciences, 55, 161-162.
87. Holi, M., Auvinen-Lintunen, L., Lindberg, N., Tani, P., & Virkkkunen, M. (2006). Inverse correlation between severity of psychopathic traits and serum cortisol levels in young adult violent male offenders. Psychopathology, 39, 102-104.
88. Howard, M. O., Kivlahan, D., & Walker, R. D. (1997). Cloninger's tridimensional theory of personality and psychopathology: Applications to substance use disorders. Journal of Studies on Alcoholism, 58, 48-66.
89. Hugo, F., van Heerden, B., Zungu-Dirwayi, N., & Stein, D. J. (1999). Functional brain imaging in obsessive-compulsive disorder secondary to neurological lesions. Depression and Anxiety, 10, 129-136.
90. Insel, T. R., Mueller, E. A., Alterman, I., Linnoila, M., & Murphy, D. L. (1985). Obsessive-compulsive disorder and serotonin: Is there a connection? Biological Psychiatry, 20, 1174-1188.
91. Johansson, P., Andershed, H., Kerr, M., & Levander, S. (2002). On the operationalization of psychopathy: Further support for a three-faceted personality oriented model. Acta Psychiatrica Scandinavica, 412(Suppl.), 81-85.
92. Johansson, P., Kerr, M., & Andershed, H. (2005). Linking adult psychopathy with childhood hyperactivity-impulsivity-attention problems and conduct problems through retrospective self-reports. Journal of Personality Disorders, 19, 94-101.
93. Jones, M. K., & Menzies, R. G. (1998). Danger ideation reduction therapy (DIRT) for obsessive-compulsive washers: A controlled trial. Behavioral Research and Therapy, 36, 959-970.
94. Jurado, M. A., & Junque, C. (2000). Criminal behavior after orbitofrontal lesion [in Spanish]. Actas Espanolas de Psiquiatria, 28, 337-341.
95. Kim, K. W., & Lee, D. Y. (2002). Obsessive-compulsive disorder associated with a left orbitofrontal infarct. Journal of Neuropsychiatry and Clinical Neurosciences, 14, 88-89.
96. Klein, R. G., Abikoff, H., Klass, E., Ganeles, D., Seese, L. M., & Pollack, S. (1997). Clinical efficacy of methylphenidate in conduct disorder with and without attention deficit hyperactivity disorder. Archives of General Psychiatry, 54, 1073-1080.
97. Koenig, L. B., McGue, M., Krueger, R. F., & Bouchard, J. J. (2007). Religiousness, antisocial behavior and altruism: Genetic and environmental mediation. Journal of Personality, 75, 265-290.
98. Krikorian, R., Zimmerman, M. E., & Fleck, D. E. (2004). Inhibitory control in obsessivecompulsive disorder. Brain and Cognition, 54, 257-259.
99. Kuikka, J. T., Tiihonen, J., Bergstrom, K. A., Karhu, J., Rasanen, P., & Eronen, M. (1998). Abnormal structure of human striatal dopamine re-uptake sites in habitually violent offenders: A fractal analysis. Neuroscience Letters, 253, 195-197.
100. Kwon, J. S., Kim, J. J., Lee, D. W., Lee, J. S., Lee, D. S., Kim, M. S., et al. (2003). Neural correlates of clinical symptoms and cognitive dysfunctions in obsessive-compulsive disorder. Psychiatry Research: Neuroimaging, 122, 37-47.
101. Ladisich, W., & Feil, W. B. (1988). Empathy in psychiatric patients. British Journal of Medical Psychology, 61, 155-162.
102. Laplane, D., Boulliat, J., Baron, J. C., Pillon, B., & Baulac, M. (1988). Comportement compulsif d'allure obsessionnelle par lésion bilatérale des noyaux lenticulaires: Un nouveau cas [Obsessive- compulsive-like behaviour with bilateral lesions of the lentiform nuclei: Another case]. Encéphale, 14, 27-32.
103. Laplane, D., Levasseur, M., Pillon, B., Dubois, B., Baulac, M., Mazoyer, B., et al. (1989). Obsessive-compulsive and other behavioural changes with bilateral basal ganglia lesions: A neuropsychological, magnetic resonance imaging and positron tomography study. Brain, 112, 699-725.
104. Lappalainen, J., Long, J. C., Eggert, M., Ozaki, N., Robin, R. W., Brown, G. L., et al. (1998). Linkage of antisocial alcoholism to the serotonin 5-HT1B receptor gene in 2 populations. Archives of General Psychiatry, 55, 989-994.
105. Leckman, J. F., Goodman, W. K., Anderson, G. M., Riddle, M. A., Chappell, P. B., McSwiggan-Hardin, M. T., et al. (1995). Cerebrospinal fluid biogenic amines in obsessive compulsive disorder, Tourette's syndrome, and healthy controls. Neuropsychopharmacology, 12, 73-86.
106. Lee, M., & Prentice, N. M. (1988). Interrelations of empathy, cognition, and moral reasoning with dimensions of juvenile delinquency. Journal of Abnormal Child Psychology, 16, 127-139.
107. Lei, W., Jiao, Y., Del Mar, N., & Reiner, A. (2004). Evidence for differential cortical input to direct pathway versus indirect pathway striatal projection neurons in rats. Journal of Neuroscience, 24, 8289-8299.
108. Levy, R., & Dubois, B. (2006). Apathy and the functional anatomy of the prefrontal cortex-basal ganglia circuits. Cerebral Cortex, 16, 916-928.
109. Lewis, C. L. (1998). Cleanliness is next to godliness: Religiosity and obsessiveness. Journal of Religion and Health, 37, 49-61.
110. Lidberg, L., Levander, S., Schalling, D., & Lidberg, Y. (1978). Urinary catecholamines, stress, and psychopathy: A study of arrested men awaiting trial. Psychosomatic Medicine, 40, 116-125.
111. Litvan, I., & Kulisevsky, J. (2003). Agitation and apathy in hyper and hypokinetic movement disorders. In M. A. Bédard, Y. Agid, S. Chouinard, S. Fahn, A. D. Korczyn, & P. Lespérance (Eds.), Mental and behavioral dysfunction in movement disorders (pp. 351-369). Totowa, NJ: Humana Press.
112. Loney, B. R., Butler, M. A., Lima, E.., Counts, C., & Eckel, L. A. (2006). The relation between salivary cortisol, callous-unemotional traits, and conduct problems in an adolescent non-referred sample. Journal of Child Psychology and Psychiatry, 47, 30-36.
113. Luo, Q., Nakic, M., Wheatley, T., Richell, R., Martin, A., & Blair, R. J. (2006). The neural basis of implicit moral attitude: An IAT study using event-related fMRI. Neuroimage, 30, 1449-1457.
114. Mahendran, R. (2000). Obsessive compulsive disorder following left middle cerebral artery infarct. Singapore Medical Journal, 41, 498-499.
115. Maier, T. (2004). On phenomenology and classification of hoarding: A review. Acta Psychiatrica Scandinavica, 110, 323-337.
116. Malloy, P., Bihrle, A., Duffy, J., & Cimino, C. (1993). The orbitomedial frontal syndrome. Archives of Clinical Neuropsychology, 8, 185-201.
117. Mantere, T., Tupala, E., Hal, H., Sarkioja, T., Rasanen, P., Bergstrom, K., et al. (2002). Serotonin transporter distribution and density in the cerebral cortex of alcoholic and nonalcoholic comparison subjects: A whole-hemisphere autoradiography study. American Journal of Psychiatry, 159, 599-606.
118. Markovitz, P. J. (2004). Recent trends in the pharmacotherapy of personality disorders. Journal of Personality Disorders, 18, 90-101.
119. Marlowe, W. B. (1992). The impact of a right prefrontal lesion on the developing brain. Brain and Cognition, 20, 205-213.
120. Masi, G., Milone, A., Canepa, G., Millepiedi, S., Mucci, M., & Muaratori, F. (2006). Olanzapine treatment in adolescents with severe conduct disorder. European Psychiatry, 21, 51-57.
121. Mateer, C. A., & Williams, D. (1991). Effects of frontal lobe injury in childhood. Developmental Neuropsychology, 7, 359-376.
122. Matsunaga, H., Kiriike, N., Matsui, T., Iwasaki, Y., Koshimune, K., Ohya, K., & Stein, D. J. (2001). A comparative study of clinical features between pure checkers and pure washers categorized using a lifetime symptom rating method. Psychiatry Research, 105, 221-229.
123. Max, J. E., Smith, W. L., Jr., Lindgren, S. D., Robin, D. A., Mattheis, P., Stierwalt, J., & Morrisey, M. (1995). Case study: Obsessive-compulsive disorder after severe traumatic brain injury in an adolescent. Journal of the American Academy of Child and Adolescent Psychiatry, 34, 45-49.
124. McDougle, C. J., Epperson, C. N., Price, L. H., & Gelernter, J. (1998). Evidence for linkage disequilibrium between serotonin transporter protein gene (SLC6A4) and obsessive compulsive disorder. Molecular Psychiatry, 3, 270-273.
125. McHaffie, J. G., Stanford, T. R., Stein, B. E., Coizet, V., & Redgrave, P. (2005). Subcortical loops through the basal ganglia. Trends in Neurosciences, 28, 401-407.
126. Meyers, C. A., Berman, S. A., Sheibel, R. S., & Hayman, A. (1992). Case report: Acquired antisocial personality disorder associated with unilateral left orbital frontal lobe damage. Journal of Psychiatry and Neuroscience, 17, 121-125.
127. Middleton, F. A. (2003). Fundamental and clinical evidence for basal ganglia influences on cognition. In M. A. Bédard, Y. Agid, S. Chouinard, S. Fahn, A. D. Korczyn, & P. Lespérance (Eds.), Mental and behavioral dysfunction in movement disorders (pp. 13-35). Totowa, NJ: Humana Press.
128. Mitchell, D. G., Avny, S. B., & Blair, R. J. (2006). Divergent patterns of aggressive and neurocognitive characteristics in acquired versus developmental psychopathy. Neurocase, 12, 164-178.
129. Moll, J., de Oliveira-Souza, R., Moll, F. T., Ignacio, F. A., Bramati, I. E., Caparelli-Daquer, E. M., & Eslinger, P. J. (2005). The moral affiliations of disgust: A functional MRI study. Cognitive and Behavioral Neurology, 18, 68-78.
130. Monteleone, P., Catapano, F., Tortorella, A., Di Martino, S., & Maj, M. (1995). Plasma melatonin and cortisol circadian patterns in patients with obsessive-compulsive disorder before and after fluoxetine treatment. Psychoneuroendocrinology, 20, 763-770.
131. Muller, J. L., Schuierer, G., Marienhagen, J., Putzhammer, A., & Klein, H. E. (2003). Acquired psychopathy and the neurobiology of emotion and violence [in German]. Psychiatrische Praxis, 30, S221-S225.
132. Murad, A. (1999). Orbitofrontal syndrome in psychiatry. Encephale, 25, 634-637.
133. Nambu, A. (2004). A new dynamic model of the cortico-basal ganglia loop. Progress in Brain Research, 143, 461-466.
134. Nicholls, T. L., & Petrila, J. (2005). Gender and psychopathy: An overview of important issues and introduction to the special issue. Behavioral Sciences and the Law, 23, 729-741.
135. Nicolini, H., Cruz, C., Paez, F., & Camarena, B. (1998). Dopamine D2 and D4 receptor genes distinguish the clinical presence of tics in obsessive-compulsive disorder. Gaceta Medica de Mexico, 134, 521-527.
136. Nordin, C., & Sjodin, I. (2006). CSF monoamine patterns in pathological gamblers and healthy controls. Journal of Psychiatric Research, 40, 454-459.
137. Oades, R. D., Ropcke, B., & Eggers, C. (1994). Monoamine activity reflected in urine of young patients with obsessive compulsive disorder, psychosis with and without reality distortion and healthy subjects: An explorative analysis. Journal of Neural Transmission: General, 96, 143-159.
138. Oades, R. D., & Schepker, R. (1994). Serum gonadal steroid hormones in young schizophrenic patients. Psychoneuroendocrinology, 19, 373-385.
139. Oades, R. D., Zimmermann, B., & Eggers, C. (1996). Conditioned blocking in patients with paranoid, non-paranoid psychosis or obsessive compulsive disorder: Associations with symptoms, personality and monoamine metabolism. Journal of Psychiatric Research, 30, 369-390.
140. Ogai, M., Iyo, M., Mori, N., & Takei, N. (2005). A right orbitofrontal region and OCD symptoms: A case report. Acta Psychiatrica Scandinavica, 111, 74-77.
141. O'Leary, M. M., Loney, B. R., & Eckel, L. A. (2007). Gender differences in the association between psychopathic personality traits and cortisol response to induced stress. Psychoneuroendocrinology, 32, 183-191.
142. Opris, I., & Bruce, C. J. (2005). Neural circuitry of judgment and decision mechanisms. Brain Research: Brain Research Reviews, 48, 509-526.
143. Pardini, D. A., Lochman, J. E., & Frick, P. J. (2003). Callous/unemotional traits and social-cognitive processes in adjudicated youths. Journal of the American Academy of Child and Adolescent Psychiatry, 42, 364-371.
144. Parsian, A., & Cloninger, C. R. (2001). Serotonergic pathway genes and subtypes of alcoholism: Association studies. Psychiatric Genetics, 11, 89-94.
145. Penney, S. R., & Moretti, M. M. (2007). The relation of psychopathy to concurrent aggression and antisocial behavior in high-risk adolescent girls and boys. Behavioral Sciences and the Law, 25, 21-41.
146. Pinto, A., Mancebo, M. C., Eisen, J. L., Pagano, M. E., & Rasmussen, S. A. (2006). The Brown Longitudinal Obsessive Compulsive Study: Clinical features and symptoms of the sample at intake. Journal of Clinical Psychiatry, 67, 703-711
147. Price, B. H., Daffner, K. R., Stowe, R. M., & Mesulam, M. M. (1990). The comportemental learning disabilities of early frontal lobe damage. Brain, 113, 1383-1393.
148. Pridmore, S., Chambers, A., & McArthur, M. (2005). Neuroimaging in psychopathy. Australian and New Zealand Journal of Psychiatry, 39, 856-865.
149. Radomsky, A. S., & Rachman, S. (2004). Symmetry, ordering and arranging compulsive behaviour. Behavioral Research and Therapy, 42, 893-913.
150. Richfield, E. K., Twyman, R., & Berent, S. (1987). Neurological syndrome following bilateral damage to the head of the caudate nuclei. Annals of Neurology, 22, 768-771.
151. Rodrigo-Escalona, P., Adair, J. C., Roberts, B. B., & Graeber, D. A. (1997). Obsessive-compulsive disorder following bilateral globus pallidus infarction. Biological Psychiatry, 42, 410-412.
152. Rogers, R., Johansen, J., Chang, J. J., & Salekin, R. T. (1997). Predictors of adolescent psychopathy: Oppositional and conduct-disordered symptoms. Journal of the American Academy of Psychiatry and Law, 25, 261-271.
153. Rolls, E. T. (2004). The functions of the orbitofrontal cortex. Brain and Cognition, 55, 11-29.
154. Rosenberg, D. R., & Hanna, G. L. (2000). Genetic and imaging strategies in obsessive-compulsive disorder: Potential implications for treatment development. Biological Psychiatry, 48, 1210-1222.
155. Roth, R. M., Baribeau, J., Milovan, D. L., & O'Connor, K. (2004). Speed and accuracy on tests of executive function in obsessive-compulsive disorder. Brain and Cognition, 54, 263-265.
156. Rowe, R., Maughan, B., & Eley, T. C. (2006). Links between antisocial behavior and depressed mood: The role of life events and attributional style. Journal of Abnormal Child Psychology, 34, 293-302.
157. Rowe, R., Maughan, B., Worthman, C. M., Costello, E. J., & Angold, A. (2003). Testosterone, antisocial behavior, and social dominance in boys: Pubertal development and biosocial interaction. Biological Psychiatry, 55, 546-552.
158. Rutter, M., Kim-Cohen, J., & Maughan, B. (2006). Continuities and discontinuities in psychopathology between childhood and adult life. Journal of Child Psychology and Psychiatry and Allied Disciplines, 47, 276-279.
159. Salekin, R. T., Neumann, C. S., Leistico, A. M., & Zalot, A. A. (2004). Psychopathy in youth and intelligence: An investigation of Cleckley's hypothesis. Journal of Clinical Child and Adolescent Psychology, 33, 731-742.
160. Salekin, R. T., Ziegler, T. A., Larrea, M. A., Anthony, V. L., & Bennett, A. D. (2003). Predicting dangerousness with two Millon Adolescent Clinical Inventory psychopathy scales: The importance of egocentric and callous traits. Journal of Personality Assessment, 80, 154-163.
161. Sander, T., Harms, H., Dufeu, P., Kuhn, S., Hoehe, M., Lesch, K. P., et al. (1998). Serotonin transporter gene variants in alcohol-dependent subjects with dissocial personality disorder. Biological Psychiatry, 43, 908-912.
162. Saxena, S., Bota, R. G., & Brody, A. L. (2001). Brain-behavior relationships in obsessive-compulsive disorder. Seminars in Clinical Neuropsychiatry, 6, 82-101.
163. Saxena, S., Brody, A. L., Maidment, K. M., Smith, E. C., Zohrabi, N., Katz, E., et al. (2004). Cerebral glucose metabolism in obsessive-compulsive hoarding. American Journal of Psychiatry, 161, 1038-1048.
164. Schludermann, E. H., Schludermann, S. M., & Huynh, C. L. (2007). Religiosity, prosocial values and adjustment among students in catholic schools in Canada. Journal of Beliefs and Values, 21, 99-115.
165. Schmidt, L. G., Sander, T., Kuhn, S., Smolka, M., Rommelspacher, H., Samochowiec, J., & Lesch, K. P. (2000). Different allele distribution of a regulatory MAOA gene promoter polymorphism in antisocial and anxious-depressive alcoholics. Journal of Neural Transmission, 107, 681-689.
166. Schwartz, J. M. (1996). Brain lock: Free yourself from obsessive-compulsive behavior. New York: Harper/Collins Publisher.
167. Seibyl, J. P., Krystal, J. H., Goodman, W. K., & Price, L. H. (1989). Obsessive-compulsive symptoms in a patient with a right frontal lobe lesion: Response to lithium augmentation of tranylcypromine. Neuropsychiatry, Neuropsychology, and Behavioral Neurology, 1, 295-299.
168. Shavelson, R. C. (1996). Statistical reasoning for the behavioral sciences. Boston: Allyn & Bacon.
169. Sher, K. J., & Trull, T. J. (1994). Personality and disinhibitory psychopathology: Alcoholism and antisocial personality disorder. Journal of Abnormal Psychology, 103, 92-102.
170. Shoval, G., Zalsman, G., Sher, L., Apter, A., & Weizman, A. (2006). Clinical characteristics of inpatient adolescents with severe obsessive-compulsive disorder. Depression and Anxiety, 23, 62-70.
171. Simpson, H. B., Lombardo, I., Slifstein, M., Huang, H. Y., Hwang, D. R., Abi-Dargham, A., et al. (2003). Serotonin transporters in obsessive-compulsive disorder: A positron emission tomography study with [(11)C]McN 5652. Biological Psychiatry, 54, 1414-1421.
172. Simpson, S., & Baldwin, B. (1995). Neuropsychiatry and SPECT of an acute obsessive-compulsive syndrome patient. British Journal of Psychiatry, 166, 390-392.
173. Singer, T., Kiebel, S. J., Winston, J. S., Dolan, R. J., & Frith, C. D. (2004). Brain responses to the acquired moral status of faces. Neuron, 41, 653-662.
174. Soderstrom, H. (2003). Psychopathy as a disorder of empathy. European Child and Adolescent Psychiatry, 12, 249-252.
175. Soderstrom, H., Blennow, K., Manhem, A., & Forsman, A. (2001). CSF studies in violent offenders. I. 5-HIAA as a negative and HVA as a positive predictor of psychopathy. Journal of Neural Transmission, 108, 869-878.
176. Soderstrom, H., Hultin, L., Tulberg, M., Wikkelso, C., & Ekholm, S. (2002). Reduced frontotemporal perfusion in psychopathic personality. Psychiatry Research, 114, 81-94.
177. Stafford, E., & Cornell, D. G. (2003). Psychopathy scores predict adolescent inpatient aggression. Assessment, 10, 102-112.
178. Stalenheima, E. G., Eriksson, E., von Knorring, L., & Wide, L. (1998). Testosterone as a biological marker in psychopathy and alcoholism. Psychiatry Research, 77, 79-88.
179. Storvik, M., Tiihonen, J., Haukijarvi, T., & Tupala, E. (2006). Lower serotonin transporter binding in caudate in alcoholics. Synapse, 59, 144-151.
180. Swoboda, K. J., & Jenike, M. A. (1995). Frontal abnormalities in a patient with obsessivecompulsive disorder: The role of structural lesions in obsessive-compulsive behavior. Neurology, 45, 2130-2134.
181. Tabachnick, B. G., & Fidell, L. S. (2001). Using multivariate statistics. Needham Heights, MA: Allyn & Bacon.
182. Tallis, F., Pratt, P., & Jamani, N. (1999). Obsessive compulsive disorder, checking, and non-verbal memory: A neuropsychological investigation. Behavioral Research and Therapy, 37, 161-166.
183. Termine, C., Uggetti, C., Veggiotti, P., Balottin, U., Rossi, G., Egitto, M. G., & Lanzi, G. (2005). Long-term follow-up of an adolescent who had bilateral striatal necrosis secondary to mycoplasma pneumoniae infection. Brain Development, 27, 62-65.
184. Thapar, A., van den Bree, M., Fowler, T., Langley, K., & Whittinger, N. (2006). Predictors of antisocial behaviour in children with attention deficit hyperactivity disorder. European Child and Adolescent Psychiatry, 15, 118-125.
185. Thobois, S., Jouanneau, E., Bouvard, M., & Sindou, M. (2004). Obsessive-compulsive disorder after unilateral caudate nucleus bleeding. Acta Neurochirurgica (Wien), 146, 1027-1031.
186. Tiihonen, J., Vilkman, H., Rasanen, P., Ryynanen, O.-P., Hakko, H., Bergman, J., et al. (1998). Striatal presynaptic dopamine function in type 1 alcoholics measured with positron emission tomography. Molecular Psychiatry, 4, 156-161.
187. Tonkonogy, J., & Barreira, P. (1989). Obsessive-compulsive disorder and caudate frontal lesion. Neuropsychiatry, Neuropsychology and Behavioral Neurology, 2, 203-209.
188. Trummer, M., Eustacchio, S., Unger, F., Tillich, M., & Flaschka, G. (2002). Right hemispheric frontal lesions as a cause for anorexia nervosa report of three cases. Acta Neurochirurgica (Wien), 144, 797-801.
189. Tupala, E., Hall, H., Mantere, T., Rasanen, P., Sarkioja, T., & Tiihonen, J. (2003). Dopamine receptors and transporters in the brain reward circuits of type 1 and 2 alcoholics measured with human whole hemisphere autoradiography. Neuroimage, 19, 145-155.
190. Tupala, E., Halonen, P., & Tiihonen, J. (2006). Visualization of the cortical dopamine transporter in type 1 and 2 alcoholics with human whole hemisphere autoradiography. European Neuropsychopharmacology, 16, 552-560.
191. Ursu, S., Stenger, V. A., Shear, M. K., Jones, M. R., & Carter, C. S. (2003). Overactive action monitoring in obsessive-compulsive disorder: Evidence from functional magnetic resonance imaging. Psychological Science, 14, 347-353.
192. Van Goozen, S. H., van den Ban, E., Matthys, W., Cohen-Kettenis, P. T., Thijssen, J. H., & van Engeland, H. (2000). Increased adrenal androgen functioning in children with oppositional defiant disorder: A comparison with psychiatric and normal controls. Journal of the American Academy of Child and Adolescent Psychiatry, 39, 1446-1451.
193. Van Grootheest, D. S., Cath, D. C., Beekman, A. T., & Boomsma, D. I. (2005). Twin studies on obsessive-compulsive disorder: A review. Twin Research and Human Genetics, 8, 450-458.
194. Vanyukov, M. M., Moss, H. B., Kaplan, B. B., Kirillova, G. P., & Tarter, R. E. (2000). Antisociality, substance dependence, and the DRD5 gene: A preliminary study. American Journal of Medical Genetics, 96, 654-658.
195. Viding, E., Blair, R. J., Moffitt, T. E., & Plomin, R. (2005). Evidence for substantial genetic risk for psychopathy in 7-year-olds. Journal of Child Psychology and Psychiatry, 46, 592-597.
196. Vulink, N. C., Denys, D., Bus, L., & Westenberg, H. G. (2006). Sexual pleasure in women with obsessive-compulsive disorder? Journal of Affective Disorders, 91, 19-25.
197. Walitza, S., Wewetzer, C., Warnke, A., Gerlach, M., Geller, F., Gerber, G., et al. (2002). 5-HT2A promoter polymorphism -1438G/A in children and adolescents with obsessive-compulsive disorders. Molecular Psychiatry, 7, 1054-1057.
198. Walker, C., Thomas, J., & Allen, T. S. (2003). Treating impulsivity, irritability, and aggression of antisocial personality disorder with quetiapine. International Journal of Offender Therapy and Comparative Criminology, 47, 556-567.
199. Weilburg, J. B., Mesulam, M., Weintraub, J., Buonanno, F., Jenike, M., & Stakes, J. W. (1989). Focal striatal abnormalities in a patient with obsessive-compulsive disorder. Archives of Neurology, 46, 233-235.
200. Williams, D., & Mateer, C. A. (1992). Developmental impact of frontal lobe injury in middle childhood. Brain and Cognition, 20, 196-204.
201. Woodman, D. D., Hinton, J. W., & O'Neill, M. T. (1977). Abnormality of catecholamines balance relating to social deviance. Perceptual and Motor Skills, 45, 593-594.
202. Yates, C. M., Simpson, J., & Maloney, A. F. J. (1980). Neurochemical observations in a case of Pick's disease. Journal of the Neurological Sciences, 48, 257-263.