Identification of a fibrin-independent platelet contractile mechanism regulating primary hemostasis and thrombus growth

Blood

Volumn 112, Issue 1, 2008, Pages 90-99

  Ono, Akiko ^a   Westein, Erik ^a   Hsiao, Sarah ^a   Nesbitt, Warwick S ^a   Hamilton, Justin R ^a   Schoenwaelder, Simone M ^a   Jackson, Shaun P ^a  

^a MONASH UNIVERSITY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

BLEBBISTATIN; FIBRIN; RHO KINASE; THROMBIN; 1 (5 ISOQUINOLINESULFONYL) 2 METHYLPIPERAZINE; 2 METHYL 1 ((4 METHYL 5 ISOQUINOLINYL)SULFONYL)HOMOPIPERAZINE; 2-METHYL-1-((4-METHYL-5-ISOQUINOLINYL)SULFONYL)HOMOPIPERAZINE; DRUG DERIVATIVE; FUSED HETEROCYCLIC RINGS; MOLECULAR MOTOR; MYOSIN IIA; PROTEASE ACTIVATED RECEPTOR 4, MOUSE; PROTEASE-ACTIVATED RECEPTOR 4, MOUSE; PROTEIN KINASE INHIBITOR; PROTEINASE ACTIVATED RECEPTOR;

ANIMAL CELL; ARTICLE; BLEEDING; CONTROLLED STUDY; ENZYME INHIBITION; EXPERIMENTAL MODEL; HEMOSTASIS; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; REGULATORY MECHANISM; THROMBOCYTE ADHESION; THROMBOCYTE AGGREGATION; THROMBOCYTE AGGREGATION INHIBITION; THROMBOCYTE CONTRACTION; THROMBOCYTE FUNCTION; THROMBOGENESIS; ANIMAL; BLOOD; BLOOD CLOT RETRACTION; C57BL MOUSE; DRUG ANTAGONISM; GENETICS; IN VITRO STUDY; MOUSE MUTANT; PHYSIOLOGY; THROMBOCYTE; THROMBOCYTE ADHESIVENESS; THROMBOSIS;

1-(5-ISOQUINOLINESULFONYL)-2-METHYLPIPERAZINE; ANIMALS; BLOOD PLATELETS; CLOT RETRACTION; FIBRIN; HEMOSTASIS; HETEROCYCLIC COMPOUNDS WITH 4 OR MORE RINGS; HUMANS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MOLECULAR MOTOR PROTEINS; NONMUSCLE MYOSIN TYPE IIA; PLATELET ADHESIVENESS; PROTEIN KINASE INHIBITORS; RECEPTORS, PROTEINASE-ACTIVATED; RHO-ASSOCIATED KINASES; THROMBOSIS;

EID: 47249124947     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2007-12-127001     Document Type: Article

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