Caseinophosphopeptide-bound iron: Protective effect against gut peroxidation

Annals of Nutrition and Metabolism

Volumn 52, Issue 3, 2008, Pages 177-180

  Kibangou, Ida ^a   Bouhallab, Saïd ^b   Bureau, François ^a   Allouche, Stéphane ^a   Thouvenin, Guy ^a   Bouglé, Dominique ^a  

^a CAEN UNIVERSITY HOSPITAL   (France)

^b UMR1253   (France)

Author keywords

Casein; Caco 2 cells; Caseinophosphopeptides; Iron; Peroxidation

Indexed keywords

BETA CASEIN; CASEINOPHOSPHOPEPTIDE; FERRIC PYROPHOSPHATE; FERROUS SULFATE; IRON; MALONALDEHYDE; MILK PROTEIN; PHOSPHOPEPTIDE;

ARTICLE; CELL PROTECTION; CELL STRAIN CACO 2; CONTROLLED STUDY; FOOD PROCESSING; HUMAN; HUMAN CELL; IRON ABSORPTION; IRON DEFICIENCY; LIPID PEROXIDATION; MILK; PEROXIDATION; PRIORITY JOURNAL;

ABSORPTION; ANEMIA, IRON-DEFICIENCY; ANIMALS; BIOLOGICAL TRANSPORT; CACO-2 CELLS; CASEINS; FOOD, FORTIFIED; HUMANS; IRON; LIPID PEROXIDATION; MALONDIALDEHYDE; MILK; PEPTIDE FRAGMENTS; PROTEIN BINDING;

EID: 47249099075     PISSN: 02506807     EISSN: None     Source Type: Journal    
DOI: 10.1159/000136384     Document Type: Article

References (13)

1. Castillo-Duran C, Cassoria F: Trace minerals in human growth and development. J Pediatr Endocrinol Metab 1999;12:589-601.
2. Babbs CF: Free radicals and the etiology of colon cancer. Free Rad Biol Med 1990;8:191-200.
3. Rival SG, Fornaroli S, Boeriu CG, Wichers HJ: Caseins and casein hydrolysates: lipoxygenase inhibitory properties. J Agric Food Chem 2001;49:287-294.
4. Kansci G, Genot C, Meynier F, Gaucheron F, Chobert JC: β-Caseinophosphopeptide (f1-25) confers on β-casein tryptic hydrolysate an antioxidant activity during iron/ascorbate-induced oxidation of liposomes. Lait 2004;84:449-462.
5. Aït-Oukhatar N, Bouhallab S, Arhan P, Maubois JL, Drosdowsky M, Bouglé D: Iron tissue storage and hemoglobin levels of deficient rats repleted with iron bound to the casein phosphopeptide 1-25 of β casein. J Agric Food Chem 1999;47:2786-2790.
6. Aït-Oukhatar N, Pérès JM, Bouhallab S, Neuville D, Bureau F, Bouvard G, Arhan P, Bouglé D: Bioavailability of caseinophosphopeptide bound iron. J Lab Clin Med 2002;140:290-294.
7. Nunez MT, Tapia V, Toyokuni S, Okada S: Iron oxidative damage in colon carcinoma (Caco-2) cells. Free Rad Res 2001;34:57-68.
8. Richard MJ, Portal B, Meo J, Coudray C, Hadjian A, Favier A: A malondialdehyde kit evaluated for determining plasma and lipoprotein fractions that react with thiobarbituric acid. Clin Chem 1992;38:704-709.
9. Yeung AC, Glahn RP, Miller DD: Dephosphorylation of sodium caseinate, enzymatically hydrolyzed casein and casein phosphopeptides by intestinal alkaline phosphatase: implications for iron availability. J Nutr Biochem 2001;12:292-299.
10. Nelson RL: Iron and colorectal cancer risk: human studies. Nutr Rev 2001;59:140-148.
11. Aït-Oukhatar N, Bouhallab S, Bureau F, Arhan P, Maubois JL, Bouglé D: In vitro digestion of caseinophosphopeptide-iron complex. J Dairy Res 2000;67:125-129.
12. Au AP, Reddy MB: Caco-2 cells can be used to assess human iron bioavailability from a semipurified meal. J Nutr 2000;130:1329-1334.
13. Draper HH, Polensek L, Hadley M, McGirr MG: Urinary malondialdehyde as an indicator of lipid peroxidation in the diet and in the tissues. Lipids 1984;19:836-843.