Iron tissue storage and hemoglobin levels of deficient rats repleted with iron bound to the caseinophosphopeptide 1-25 of β-casein

Journal of Agricultural and Food Chemistry

Volumn 47, Issue 7, 1999, Pages 2786-2790

  Aît Oukhatar, Nabil ^a   Bouhallab, Said ^b   Arhan, Pierre ^a   Maubois, Jean Louis ^b   Drosdowsky, Michel ^a   Bouglé, Dominique ^a,c  

^a CAEN UNIVERSITY HOSPITAL   (France)

^b CEMAGREF   (France)

^c CHU Clemenceau   (France)

Author keywords

Bioavailability; Casein phosphopeptide; Hemoglobin; Iron; Milk proteins; Rat; Tissue storage

Indexed keywords

BETA CASEIN; CASEIN; CASEINOPHOSPHOPEPTIDE 1-25; HEMOGLOBIN; IRON; IRON BINDING PROTEIN; LIGAND; MILK PROTEIN; PEPTIDE FRAGMENT; PHOSPHOPEPTIDE;

AMINO ACID SEQUENCE; ANIMAL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIOAVAILABILITY; CHEMISTRY; CONTROLLED STUDY; DIGESTIVE FUNCTION; DOSE RESPONSE; IRON ABSORPTION; IRON BINDING CAPACITY; IRON BLOOD LEVEL; IRON STORAGE; LIVER; MALE; METABOLISM; MOLECULAR GENETICS; NONHUMAN; PROTEIN BINDING; RAT; RAT STRAIN; SPLEEN;

AMINO ACID SEQUENCE; ANIMALS; CASEINS; HEMOGLOBINS; IRON; LIVER; MALE; MOLECULAR SEQUENCE DATA; PEPTIDE FRAGMENTS; PROTEIN BINDING; RATS; RATS, SPRAGUE-DAWLEY; SPLEEN;

EID: 17744407094     PISSN: 00218561     EISSN: None     Source Type: Journal    
DOI: 10.1021/jf981018k     Document Type: Article

References (39)

1. Baumy, J. J.; Brulé, G. Effect of pH and ionic strength on the binding of bivalent cations to β-casein. Lait 1988, 68, 409-418.
2. Beard, J. L.; Dawson, H.; Pinero, D. J. Iron metabolism: a comprehensive review. Nutr. Rev. 1996, 54, 295-317.
3. Berrocal, R.; Chanton, S.; Juillerat, M. A.; Pavillard, B.; Scherz, J. C.; Jost, R. Tryptic phosphopeptides from whole casein. II. Physicochemical properties related to the solubilization of calcium. J. Dairy Res. 1989, 56, 335-341.
4. Bouhallab, S.; Léonil, J.; Maubois, J. L. Complexation du fer par le phosphopeptide (1-25) de la caséine β: action de l'alcalase et de la phosphatase acide. Lait 1991, 71, 435-443.
5. Brulé, G.; Fauquant, J. Interaction des protéines du lait et des oligo-éléments. Lait 1982, 62, 323-331.
6. Brulé, G.; Fauquant, J.; Maubois, J. L. Preparation of native phosphocaseinate by combining membrane ultrafiltration and ultracentrifugation. J. Dairy Sci. 1979, 62, 869-875.
7. Chabance, B.;Marteau, P.; Rambaud, P. C.; Migliore-Samour, D.; Boynard, M.; Perrotin, P.; Guillet, R.; Jollès, P.; Fiat, A. M. Casein peptide release and passage to the blood in humans during digestion of milk or yogurt. Biochimie 1998, 80, 155-165.
8. Cook, J. D.; Monsen, E. R. Food Fe absorption in human subjects. III. Comparison of the effect of animal proteins on non-heme Fe absorption. Am. J. Clin. Nutr. 1976, 29, 859-867.
9. Demott, B. J.; Dincer, B. Binding added iron to various milk proteins. J. Dairy Sci. 1976, 59, 1557-1559.
10. Dhur, A.; Galan, P.; Hercberg, S. Effects of different degrees of iron deficiency on cytochrome P450 complex and pentose phosphate pathway dehydrogenases in the rat. J. Nutr. 1989, 119, 40-47.
11. Emery, T. Iron oxidation by casein. Biochem. Biophys. Res. Commun. 1992, 182, 1047-1052.
12. Galdi, M.; Valencia, M. E. Stability of iron (III) chelates of nutritional interest. J. Food Sci. 1988, 53, 1844-1847.
13. Hegenauer, J.; Saltman, P.; Ludwig, D.; Ripley, L.; Ley, A. Iron-supplemented cow milk. Identification and spectral properties of iron bound to casein micelles. J. Agric. Food Chem. 1979, 27, 1294-1301.
14. Hurrell, R. F.; Lynch, S. R.; Trinidad, T. P.; Dassenko, S. A.; Cook, J. D. Iron absorption in humans: bovine serum albumin compared with beef muscle and egg white. Am. J. Clin. Nutr. 1988, 47, 102-107.
15. Hurrell, R. F.; Lynch, S. R.; Trinidad, P.; Dassenko, S. A.; Cook, J. D. Fe absorption in humans as influenced by bovine milk proteins. Am. J. Clin. Nutr. 1989, 49, 546-552.
16. Hurrell, R. F.; Juillerat, M. A.; Reddy, M. B.; Lynch, S. R.; Dassenko, S. A.; Cook, J. D. Soy protein, phytate, and Fe absorption in humans. Am. J. Clin. Nutr. 1992, 56, 573-578.
17. Juillerat, M. A.; Baechler, R.; Berrocal, R.; Chanton, S.; Scherz, J. C.; Jost, R. Tryptic phosphopeptides from whole casein. Preparation and analysis by fast protein liquid chromatography. J. Dairy Res. 1989, 56, 603-611.
18. Kane, A. P.; Miller, M. S. In vitro estimation of the effets of selected proteins on iron bioavailability. Am. J. Clin. Nutr. 1984, 39, 393-401.
19. Kasai, T.; Iwasaki, R.; Tanaka, M.; Kiriyama, S. Caseinphosphopeptides (CPP) in feces and contents in digestive tract of rats fed casein and CPP fractions. Biosci., Biotechnol., Biochem. 1995, 59, 26-30.
20. Kim, M.; Lee, D. T.; Lee, Y. S. Iron absorption and intestinal solubility in rats are influenced by dietary proteins. Nutr. Res. 1995, 15, 1705-1716.
21. Mahoney, A. W.; Hendricks, D. G. Potential of the rat as a model for predicting iron bioavailability for humans. Nutr. Res. 1984, 4, 913-922.
22. Manson, W.; Annan, W. D. The structure of phosphopeptide derived from β casein. Arch. Biochem. Biophys. 1971, 145, 16-26.
23. Martinez-Torres, C.; Romano, E.; Layrisse, M. Effect of cysteine on Fe absorption in man. Am. J. Clin. Nutr. 1981, 34, 322-327.
24. Maubois, J. L.; Léonil, J. Peptides du lait à activité biologique. Lait 1989, 69, 245-269.
25. Meisel, H.; Frister, H. Chemical characterization of bioactive peptides from in vivo digests of casein. J. Dairy Res. 1989, 56, 343-349.
26. Miller, D. D.; Berner, L. A. Is solubility in vitro a reliable predictor of iron bioavailability? Biol. Trace Elem. Res. 1989, 19, 11-24.
27. Morris, E. R. An overview of current information on bioavailability of dietary iron to humans. Fed. Proc. 1983, 42, 1716-1720.
28. Naito, H.; Kawakami, A.; Imamura, T. In vivo formation of phospho-peptides with calcium binding properties in the small intestinal tract of the rat fed casein. Agric. Biol. Chem. 1972, 36, 409-415.
29. National Research Council, Sucommittee on Laboratory Animal Nutrition; Committee on Animal Nutrition-Board on Agriculture. Nutrient requirements of the Laboratory Rat. In Nutrient requirements of Laboratory Animals, 4th ed.; National Academy Press: Washington, DC, 1995.
30. Pantzar, N.; Weström, B. R.; Luts, A.; Lundin, S. Regional small-intestinal permeability in vitro to different-sized dextrans and proteins in the rat. Scand. J. Gastroenterol. 1993, 28, 205-211.
31. Pérès, J. M.; Bouhallab, S.; Bureau, F.; Maubois, J. L.; Arhan, P.; Bouglé, D. Absorption digestive du fer lié au caséino-phosphopeptide (1-25) de la β caséine. Lait 1997, 77, 433-440.
32. Pérès, J. M.; Bouhallab, S.; Bureau, F.; Maubois, J. L.; Arhan, P.; Bouglé, D. Mechanisms of absorption of caseinophosphopeptide bound iron. J. Nutr. Biochem. 1999, 10, 215-222.
33. Reddy, M. B.; Cook, J. D. Assessment of dietary determinants of nonheme-iron absorption in humans and rats. Am. J. Clin. Nutr. 1991, 54, 723-728.
34. Sandström, B.; Arvidsson, B.; Cederblad, A.; Björn-Rasmussen, E. Zinc absorption from composite meals I. The significance of wheat extraction rate, zinc, calcium, and protein content in meals based on bread. Am. J. Clin. Nutr. 1980, 33, 739-745.
35. Sato, R.; Shindo, M.; Gunshin, H.; Noguchi, T.; Naito, H. Characterization of phosphopeptide derived from bovine β-casein: an inhibitor to intra-intestinal precipitation of calcium phosphate. Biochim. Biophys. Acta 1991, 1077, 413-415.
36. Siimes, M. A.; Refino, C.; Dallman, P. R. Manifestation of iron deficiency at various levels of dietary intake. Am. J. Clin. Nutr. 1980, 33, 570-574.
37. Thompson, D. B.; Erdman, J. W. The effect of soy protein isolate in the diet on retention by the rat of Fe from radio-labeled test meals. J. Nutr. 1984, 114, 307-311.
38. Wapnir, R. A. Chapter 6: Nutritional factors, proteins and the absorption of iron and cobalt. In Protein Nutrition and Mineral Absorption; Wapnir, R. A., Ed.; CRC Press: Boca Raton, FL, 1990; pp 99-129.
39. West, D. W. Structure and function of phosphorylated residues of casein. J. Dairy Res. 1986, 53, 333-352.