Mechanism of trifluralin-induced thyroid tumors in rats

Toxicology Letters

Volumn 180, Issue 1, 2008, Pages 38-45

  Saghir, Shakil A ^a   Charles, Grantley D ^a   Bartels, Michael J ^a   Kan, Lynn H L ^a   Dryzga, Mark D ^a   Brzak, Kathy A ^a   Clark, Amy J ^a  

^a DOW CHEMICAL COMPANY   (United States)

Author keywords

Dinitroanilines; Thyroid stimulating hormone (TSH); Thyroid tumor in rats; Thyroxine (T4); Trifluralin; Triiodothyronine (T3)

Indexed keywords

GLUCURONOSYLTRANSFERASE 1A1; GLUCURONOSYLTRANSFERASE 1A6; LIOTHYRONINE; PHENOBARBITAL; THYROTROPIN; THYROXINE 5 DEIODINASE; TRIFLURALIN;

ARTICLE; BILE FLOW; BODY WEIGHT; CELL PROLIFERATION; CONTROLLED STUDY; ENZYME ACTIVITY; GENE EXPRESSION; GOITER; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HORMONE BLOOD LEVEL; HORMONE RELEASE; HORMONE SYNTHESIS; MALE; NONHUMAN; ORGAN WEIGHT; PRIORITY JOURNAL; RAT; TANDEM MASS SPECTROMETRY; THYROID TUMOR;

ADENOCARCINOMA, FOLLICULAR; ADMINISTRATION, ORAL; ANIMAL FEED; ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GLUCURONOSYLTRANSFERASE; HERBICIDES; LIVER; MALE; MICROSOMES, LIVER; ORGAN SIZE; RATS; RATS, INBRED F344; RNA, MESSENGER; THYROID GLAND; THYROID NEOPLASMS; THYROTROPIN; THYROXINE; TRIFLURALIN; TRIIODOTHYRONINE;

RATTUS;

EID: 47049112381     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxlet.2008.05.019     Document Type: Article

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