메뉴 건너뛰기




Volumn 142, Issue 3, 2008, Pages 457-465

Thiols in the αIIbβ3 integrin are necessary for platelet aggregation

Author keywords

IIb 3; Integrin; PCMBS; Platelets; Sulfhydryls; Thiols

Indexed keywords

5,5' DITHIOBIS(2 NITROBENZOIC ACID); ADENOSINE DIPHOSPHATE; ALPHA 2B BETA 3 INTEGRIN; APYRASE; BIOCYTIN; INTEGRIN; MANGANESE; PURINERGIC P2Y12 RECEPTOR; PURINERGIC RECEPTOR BLOCKING AGENT; THIOL; 3 (N MALEIMIDOPROPIONYL)BIOCYTIN; 3-(N-MALEIMIDOPROPIONYL)BIOCYTIN; CHLOROMERCURIBENZENESULFONIC ACID; DRUG DERIVATIVE; FIBRINOGEN RECEPTOR; LYSINE; MALEIMIDE DERIVATIVE; THIOL DERIVATIVE;

EID: 46949107560     PISSN: 00071048     EISSN: 13652141     Source Type: Journal    
DOI: 10.1111/j.1365-2141.2008.07200.x     Document Type: Article
Times cited : (16)

References (44)
  • 1
    • 0015836648 scopus 로고
    • Sulfhydryl and disulfide groups of platelet membranes. II. Determination of disulfide groups
    • Ando, Y. Steiner, M. (1973) Sulfhydryl and disulfide groups of platelet membranes. II. Determination of disulfide groups. Biochimica et Biophysica Acta, 311, 38 44.
    • (1973) Biochimica et Biophysica Acta , vol.311 , pp. 38-44
    • Ando, Y.1    Steiner, M.2
  • 2
    • 0016911328 scopus 로고
    • Distribution of free sulfhydryl and disulfide groups among platelet membrane proteins
    • Ando, Y. Steiner, M. (1976) Distribution of free sulfhydryl and disulfide groups among platelet membrane proteins. Biochimica et Biophysica Acta, 419, 51 62.
    • (1976) Biochimica et Biophysica Acta , vol.419 , pp. 51-62
    • Ando, Y.1    Steiner, M.2
  • 3
    • 0015115846 scopus 로고
    • Ultrastructural localization of contractile protein (thrombosthenin) in human platelets using an unlabeled antibody-peroxidase staining technique
    • Booyse, F.M., Sternberger, L.A., Zschocke, D. Rafelson, Jr, M.E. (1971) Ultrastructural localization of contractile protein (thrombosthenin) in human platelets using an unlabeled antibody-peroxidase staining technique. Journal of Histochemistry and Cytochemistry, 19, 540 550.
    • (1971) Journal of Histochemistry and Cytochemistry , vol.19 , pp. 540-550
    • Booyse, F.M.1    Sternberger, L.A.2    Zschocke, D.3    Rafelson Jr., M.E.4
  • 6
    • 0029025521 scopus 로고
    • Characterization of protein disulphide isomerase released from activated platelets
    • Chen, K., Detwiler, T.C. Essex, D.W. (1995) Characterization of protein disulphide isomerase released from activated platelets. British Journal of Haematology, 90, 425 431.
    • (1995) British Journal of Haematology , vol.90 , pp. 425-431
    • Chen, K.1    Detwiler, T.C.2    Essex, D.W.3
  • 7
    • 0141561935 scopus 로고    scopus 로고
    • AlphaIIbbeta3-mediated outside-in signaling induced by the agonist peptide LSARLAF utilizes ADP and thromboxane A2 receptors to cause alpha-granule secretion by platelets
    • Cho, M.J., Liu, J., Pestina, T.I., Steward, S.A., Jackson, C.W. Gartner, T.K. (2003) AlphaIIbbeta3-mediated outside-in signaling induced by the agonist peptide LSARLAF utilizes ADP and thromboxane A2 receptors to cause alpha-granule secretion by platelets. Journal of Thrombosis and Haemostasis, 1, 363 373.
    • (2003) Journal of Thrombosis and Haemostasis , vol.1 , pp. 363-373
    • Cho, M.J.1    Liu, J.2    Pestina, T.I.3    Steward, S.A.4    Jackson, C.W.5    Gartner, T.K.6
  • 8
    • 0034741711 scopus 로고    scopus 로고
    • Distinct domains of alphaIIbbeta3 support different aspects of outside-in signal transduction and platelet activation induced by LSARLAF, an alphaIIbbeta3 interacting peptide
    • Derrick, J.M., Shattil, S.J., Poncz, M., Gruppo, R.A. Gartner, T.K. (2001) Distinct domains of alphaIIbbeta3 support different aspects of outside-in signal transduction and platelet activation induced by LSARLAF, an alphaIIbbeta3 interacting peptide. Thrombosis and Haemostasis, 86, 894 901.
    • (2001) Thrombosis and Haemostasis , vol.86 , pp. 894-901
    • Derrick, J.M.1    Shattil, S.J.2    Poncz, M.3    Gruppo, R.A.4    Gartner, T.K.5
  • 9
    • 0037588974 scopus 로고    scopus 로고
    • Inactivation of the human P2Y12 receptor by thiol reagents requires interaction with both extracellular cysteine residues, Cys17 and Cys270
    • Ding, Z., Kim, S., Dorsam, R.T., Jin, J. Kunapuli, S.P. (2003) Inactivation of the human P2Y12 receptor by thiol reagents requires interaction with both extracellular cysteine residues, Cys17 and Cys270. Blood, 101, 3908 3914.
    • (2003) Blood , vol.101 , pp. 3908-3914
    • Ding, Z.1    Kim, S.2    Dorsam, R.T.3    Jin, J.4    Kunapuli, S.P.5
  • 10
    • 85047693299 scopus 로고    scopus 로고
    • Central role of the P2Y12 receptor in platelet activation
    • Dorsam, R.T. Kunapuli, S.P. (2004) Central role of the P2Y12 receptor in platelet activation. Journal of Clinical Investigation, 113, 340 345.
    • (2004) Journal of Clinical Investigation , vol.113 , pp. 340-345
    • Dorsam, R.T.1    Kunapuli, S.P.2
  • 11
    • 34247104103 scopus 로고    scopus 로고
    • Signaling and regulation of the platelet glycoprotein Ib-IX-V complex
    • Du, X 2007) Signaling and regulation of the platelet glycoprotein Ib-IX-V complex. Current Opinion in Hematology, 14, 262 269.
    • (2007) Current Opinion in Hematology , vol.14 , pp. 262-269
    • Du, X.1
  • 12
    • 0032985071 scopus 로고    scopus 로고
    • Protein disulphide isomerase mediates platelet aggregation and secretion
    • Essex, D.W. Li, M. (1999) Protein disulphide isomerase mediates platelet aggregation and secretion. British Journal of Haematology, 104, 448 454.
    • (1999) British Journal of Haematology , vol.104 , pp. 448-454
    • Essex, D.W.1    Li, M.2
  • 13
    • 0037435609 scopus 로고    scopus 로고
    • Redox control of platelet aggregation
    • Essex, D.W. Li, M. (2003) Redox control of platelet aggregation. Biochemistry, 42, 129 136.
    • (2003) Biochemistry , vol.42 , pp. 129-136
    • Essex, D.W.1    Li, M.2
  • 14
    • 33749440450 scopus 로고    scopus 로고
    • Redox modification of platelet glycoproteins
    • Essex, D.W. Li, M. (2006) Redox modification of platelet glycoproteins. Current Drug Targets, 7, 1233 1241.
    • (2006) Current Drug Targets , vol.7 , pp. 1233-1241
    • Essex, D.W.1    Li, M.2
  • 15
    • 0035918587 scopus 로고    scopus 로고
    • Protein disulfide isomerase and sulfhydryl-dependent pathways in platelet activation
    • Essex, D.W., Li, M., Miller, A. Feinman, R.D. (2001) Protein disulfide isomerase and sulfhydryl-dependent pathways in platelet activation. Biochemistry, 40, 6070 6075.
    • (2001) Biochemistry , vol.40 , pp. 6070-6075
    • Essex, D.W.1    Li, M.2    Miller, A.3    Feinman, R.D.4
  • 16
    • 4444282377 scopus 로고    scopus 로고
    • Platelet surface glutathione reductase-like activity
    • Essex, D.W., Li, M., Feinman, R.D. Miller, A. (2004) Platelet surface glutathione reductase-like activity. Blood, 104, 1383 1385.
    • (2004) Blood , vol.104 , pp. 1383-1385
    • Essex, D.W.1    Li, M.2    Feinman, R.D.3    Miller, A.4
  • 17
    • 0029062848 scopus 로고
    • Use of p-nitrophenyl disulfide to measure reductive capacity of intact cells
    • Gitler, C. Londner, M. (1995) Use of p-nitrophenyl disulfide to measure reductive capacity of intact cells. Methods in Enzymology, 251, 279 286.
    • (1995) Methods in Enzymology , vol.251 , pp. 279-286
    • Gitler, C.1    Londner, M.2
  • 18
    • 0015293166 scopus 로고
    • Further evidence for a deficient storage pool of adenine nucleotides in platelets from some patients with thrombocytopathia - "storage pool disease"
    • Holmsen, H. Weiss, H.J. (1972) Further evidence for a deficient storage pool of adenine nucleotides in platelets from some patients with thrombocytopathia - "storage pool disease". Blood, 39, 197 209.
    • (1972) Blood , vol.39 , pp. 197-209
    • Holmsen, H.1    Weiss, H.J.2
  • 19
    • 0036729271 scopus 로고    scopus 로고
    • Distinct roles of GPVI and integrin alpha(2)beta(1) in platelet shape change and aggregation induced by different collagens
    • Jarvis, G.E., Atkinson, B.T., Snell, D.C. Watson, S.P. (2002) Distinct roles of GPVI and integrin alpha(2)beta(1) in platelet shape change and aggregation induced by different collagens. British Journal of Pharmacology, 137, 107 117.
    • (2002) British Journal of Pharmacology , vol.137 , pp. 107-117
    • Jarvis, G.E.1    Atkinson, B.T.2    Snell, D.C.3    Watson, S.P.4
  • 20
    • 0023066977 scopus 로고
    • Spectrophotometric assay of thiols
    • Jocelyn, P.C. (1987) Spectrophotometric assay of thiols. Methods in Enzymology, 143, 44 67.
    • (1987) Methods in Enzymology , vol.143 , pp. 44-67
    • Jocelyn, P.C.1
  • 21
    • 0022371891 scopus 로고
    • Thiol-specific probes indicate that the beta-chain of platelet glycoprotein Ib is a transmembrane protein with a reactive endofacial sulfhydryl group
    • Kalomiris, E.L. Coller, B.S. (1985) Thiol-specific probes indicate that the beta-chain of platelet glycoprotein Ib is a transmembrane protein with a reactive endofacial sulfhydryl group. Biochemistry, 24, 5430 5436.
    • (1985) Biochemistry , vol.24 , pp. 5430-5436
    • Kalomiris, E.L.1    Coller, B.S.2
  • 23
    • 0037092952 scopus 로고    scopus 로고
    • Protease-activated receptors 1 and 4 do not stimulate G(i) signaling pathways in the absence of secreted ADP and cause human platelet aggregation independently of G(i) signaling
    • Kim, S., Foster, C., Lecchi, A., Quinton, T.M., Prosser, D.M., Jin, J., Cattaneo, M. Kunapuli, S.P. (2002) Protease-activated receptors 1 and 4 do not stimulate G(i) signaling pathways in the absence of secreted ADP and cause human platelet aggregation independently of G(i) signaling. Blood, 99, 3629 3636.
    • (2002) Blood , vol.99 , pp. 3629-3636
    • Kim, S.1    Foster, C.2    Lecchi, A.3    Quinton, T.M.4    Prosser, D.M.5    Jin, J.6    Cattaneo, M.7    Kunapuli, S.P.8
  • 24
    • 0036786353 scopus 로고    scopus 로고
    • Sustained integrin ligation involves extracellular free sulfhydryls and enzymatically catalyzed disulfide exchange
    • Lahav, J., Jurk, K., Hess, O., Barnes, M.J., Farndale, R.W., Luboshitz, J. Kehrel, B.E. (2002) Sustained integrin ligation involves extracellular free sulfhydryls and enzymatically catalyzed disulfide exchange. Blood, 100, 2472 2478.
    • (2002) Blood , vol.100 , pp. 2472-2478
    • Lahav, J.1    Jurk, K.2    Hess, O.3    Barnes, M.J.4    Farndale, R.W.5    Luboshitz, J.6    Kehrel, B.E.7
  • 25
    • 0141567629 scopus 로고    scopus 로고
    • Enzymatically catalyzed disulfide exchange is required for platelet adhesion to collagen via integrin alpha2beta1
    • Lahav, J., Wijnen, E.M., Hess, O., Hamaia, S.W., Griffiths, D., Makris, M., Knight, C.G., Essex, D.W. Farndale, R.W. (2003) Enzymatically catalyzed disulfide exchange is required for platelet adhesion to collagen via integrin alpha2beta1. Blood, 102, 2085 2092.
    • (2003) Blood , vol.102 , pp. 2085-2092
    • Lahav, J.1    Wijnen, E.M.2    Hess, O.3    Hamaia, S.W.4    Griffiths, D.5    Makris, M.6    Knight, C.G.7    Essex, D.W.8    Farndale, R.W.9
  • 26
    • 0019887749 scopus 로고
    • Isolation, purification, and partial characterization of platelet membrane glycoproteins IIb and IIIa
    • Leung, L.L., Kinoshita, T. Nachman, R.L. (1981) Isolation, purification, and partial characterization of platelet membrane glycoproteins IIb and IIIa. Journal of Biological Chemistry, 256, 1994 1997.
    • (1981) Journal of Biological Chemistry , vol.256 , pp. 1994-1997
    • Leung, L.L.1    Kinoshita, T.2    Nachman, R.L.3
  • 27
    • 10244224019 scopus 로고    scopus 로고
    • Functional and structural correlations of individual alphaIIbbeta3 molecules
    • Litvinov, R.I., Nagaswami, C., Vilaire, G., Shuman, H., Bennett, J.S. Weisel, J.W. (2004) Functional and structural correlations of individual alphaIIbbeta3 molecules. Blood, 104, 3979 3985.
    • (2004) Blood , vol.104 , pp. 3979-3985
    • Litvinov, R.I.1    Nagaswami, C.2    Vilaire, G.3    Shuman, H.4    Bennett, J.S.5    Weisel, J.W.6
  • 28
    • 1642305349 scopus 로고    scopus 로고
    • Locking the beta3 integrin I-like domain into high and low affinity conformations with disulfides
    • Luo, B.H., Takagi, J. Springer, T.A. (2004) Locking the beta3 integrin I-like domain into high and low affinity conformations with disulfides. Journal of Biological Chemistry, 279, 10215 10221.
    • (2004) Journal of Biological Chemistry , vol.279 , pp. 10215-10221
    • Luo, B.H.1    Takagi, J.2    Springer, T.A.3
  • 30
    • 0141707881 scopus 로고    scopus 로고
    • Thrombin formation
    • Mann, K.G. (2003) Thrombin formation. Chest, 124, 4S 10S.
    • (2003) Chest , vol.124
    • Mann, K.G.1
  • 31
    • 0030470605 scopus 로고    scopus 로고
    • ADP receptors on platelets
    • Mills, D.C. (1996) ADP receptors on platelets. Thrombosis and Haemostasis, 76, 835 856.
    • (1996) Thrombosis and Haemostasis , vol.76 , pp. 835-856
    • Mills, D.C.1
  • 32
    • 0028069348 scopus 로고
    • Superfibronectin is a functionally distinct form of fibronectin
    • Morla, A., Zhang, Z. Ruoslahti, E. (1994) Superfibronectin is a functionally distinct form of fibronectin. Nature, 367, 193 196.
    • (1994) Nature , vol.367 , pp. 193-196
    • Morla, A.1    Zhang, Z.2    Ruoslahti, E.3
  • 33
    • 0015523377 scopus 로고
    • Studies on the proteins of human platelet membranes
    • Nachman, R.L. Ferris, B. (1972) Studies on the proteins of human platelet membranes. Journal of Biological Chemistry, 247, 4468 4475.
    • (1972) Journal of Biological Chemistry , vol.247 , pp. 4468-4475
    • Nachman, R.L.1    Ferris, B.2
  • 34
    • 0000179078 scopus 로고    scopus 로고
    • Platelet membranes and receptors
    • In: ed. by. J. Loscalzo. A.I. Schafer. pp. Williams & Wilkins, Baltimore.
    • Peerschke, E.I.B. Lopez, J.A. (1998) Platelet membranes and receptors. In: Thrombosis and Hemorrhage (ed. by J. Loscalzo A.I. Schafer pp. 229 260. Williams & Wilkins, Baltimore.
    • (1998) Thrombosis and Hemorrhage , pp. 229-260
    • Peerschke, E.I.B.1    Lopez, J.A.2
  • 35
    • 0032544984 scopus 로고    scopus 로고
    • Platelet membrane actin may be partially embedded in lipid bilayer and disulfide linked
    • Qingqi, Z. Stracher, A. (1998) Platelet membrane actin may be partially embedded in lipid bilayer and disulfide linked. Biochemical and Biophysical Research Communications, 252, 407 411.
    • (1998) Biochemical and Biophysical Research Communications , vol.252 , pp. 407-411
    • Qingqi, Z.1    Stracher, A.2
  • 36
    • 0023552804 scopus 로고
    • ADP-induced platelet shape change and mobilization of cytoplasmic ionized calcium are mediated by distinct binding sites on platelets: 5′-p-fluorosulfonylbenzoyladenosine is a weak platelet agonist
    • Rao, A.K. Kowalska, M.A. (1987) ADP-induced platelet shape change and mobilization of cytoplasmic ionized calcium are mediated by distinct binding sites on platelets: 5′-p-fluorosulfonylbenzoyladenosine is a weak platelet agonist. Blood, 70, 751 756.
    • (1987) Blood , vol.70 , pp. 751-756
    • Rao, A.K.1    Kowalska, M.A.2
  • 37
    • 0018759764 scopus 로고
    • Identification of four major classes of sulfhydryl groups in human blood platelets. Ferricyanide titration of spin-labeled platelets
    • Robey, F.A., Jamieson, G.A. Hunt, J.B. (1979) Identification of four major classes of sulfhydryl groups in human blood platelets. Ferricyanide titration of spin-labeled platelets. Journal of Biological Chemistry, 254, 1010 1012.
    • (1979) Journal of Biological Chemistry , vol.254 , pp. 1010-1012
    • Robey, F.A.1    Jamieson, G.A.2    Hunt, J.B.3
  • 40
    • 0025109879 scopus 로고
    • Free thiols of platelet thrombospondin. Evidence for disulfide isomerization
    • Speziale, M.V. Detwiler, T.C. (1990) Free thiols of platelet thrombospondin. Evidence for disulfide isomerization. Journal of Biological Chemistry, 265, 17859 17867.
    • (1990) Journal of Biological Chemistry , vol.265 , pp. 17859-17867
    • Speziale, M.V.1    Detwiler, T.C.2
  • 42
    • 0346463126 scopus 로고    scopus 로고
    • Redox modulation of integrin [correction of integin] alpha IIb beta 3 involves a novel allosteric regulation of its thiol isomerase activity
    • Walsh, G.M., Sheehan, D., Kinsella, A., Moran, N. O'Neill, S. (2004) Redox modulation of integrin [correction of integin] alpha IIb beta 3 involves a novel allosteric regulation of its thiol isomerase activity. Biochemistry, 43, 473 480.
    • (2004) Biochemistry , vol.43 , pp. 473-480
    • Walsh, G.M.1    Sheehan, D.2    Kinsella, A.3    Moran, N.4    O'Neill, S.5
  • 43
    • 8544259562 scopus 로고    scopus 로고
    • Structural basis for allostery in integrins and binding to fibrinogen-mimetic therapeutics
    • Xiao, T., Takagi, J., Coller, B.S., Wang, J.H. Springer, T.A. (2004) Structural basis for allostery in integrins and binding to fibrinogen-mimetic therapeutics. Nature, 432, 59 67.
    • (2004) Nature , vol.432 , pp. 59-67
    • Xiao, T.1    Takagi, J.2    Coller, B.S.3    Wang, J.H.4    Springer, T.A.5
  • 44
    • 0034704162 scopus 로고    scopus 로고
    • A redox site involved in integrin activation
    • Yan, B. Smith, J.W. (2000) A redox site involved in integrin activation. Journal of Biological Chemistry, 275, 39964 39972.
    • (2000) Journal of Biological Chemistry , vol.275 , pp. 39964-39972
    • Yan, B.1    Smith, J.W.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.