Association between endothelial progenitor cell depletion in blood and mild-to-moderate renal insufficiency in stable angina

Nephrology Dialysis Transplantation

Volumn 23, Issue 7, 2008, Pages 2265-2273

  Surdacki, Andrzej ^a   Marewicz, Ewa ^a   Wieteska, Ewa ^a   Szastak, Grzegorz ^a   Rakowski, Tomasz ^a   Wieczorek Surdacka, Ewa ^a   Dudek, Dariusz ^a   Pryjma, Juliusz ^a   Dubiel, Jacek S ^a  

^a JAGIELLONIAN UNIVERSITY   (Poland)

Author keywords

Coronary artery disease; Endothelial progenitor cells; Renal insufficiency

Indexed keywords

CD34 ANTIGEN; ERYTHROPOIETIN; HOMOCYSTEINE; VASCULAR CELL ADHESION MOLECULE 1; VASCULOTROPIN RECEPTOR 2;

ADULT; AGED; ANEMIA; ANGIOCARDIOGRAPHY; ARTICLE; CARDIOVASCULAR RISK; CONTROLLED STUDY; CORONARY ARTERY DISEASE; CORRELATION ANALYSIS; DEPLETION; DISEASE ASSOCIATION; DISEASE SEVERITY; ENDOTHELIAL DYSFUNCTION; ENDOTHELIAL PROGENITOR CELL; ENDOTHELIUM INJURY; FLOW CYTOMETRY; GLOMERULUS FILTRATION RATE; HEMOGLOBIN BLOOD LEVEL; HUMAN; KIDNEY FAILURE; LEUKOCYTE COUNT; MAJOR CLINICAL STUDY; MALE; OUTCOME ASSESSMENT; PREDICTION; PRIORITY JOURNAL; PROGNOSIS; PROTEIN BLOOD LEVEL; STABLE ANGINA PECTORIS; STEM CELL; TISSUE REPAIR;

AGED; ANGINA PECTORIS; ANTIGENS, CD34; CELL COUNT; CORONARY ARTERY DISEASE; ENDOTHELIUM, VASCULAR; GLOMERULAR FILTRATION RATE; HUMANS; MALE; MESENCHYMAL STEM CELLS; MIDDLE AGED; MULTIVARIATE ANALYSIS; RENAL INSUFFICIENCY; RISK FACTORS; VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-2;

EID: 46849119202     PISSN: 09310509     EISSN: 14602385     Source Type: Journal    
DOI: 10.1093/ndt/gfm943     Document Type: Article

References (73)

1. Sarnak MJ, Levey AS, Schoolwerth AC et al. Kidney disease as a risk factor for development of cardiovascular disease: a statement from the American Heart Association Councils on Kidney in Cardiovascular Disease, High Blood Pressure Research, Clinical Cardiology, and Epidemiology and Prevention. Circulation 2003; 108: 2154-2169
2. Weiner DE, Tabatabai S, Tighiouart H et al. Cardiovascular outcomes and all-cause mortality: exploring the interaction between CKD and cardiovascular disease. Am J Kidney Dis 2006; 48: 392-401
3. Go AS, Chertow GM, Fan D et al. Chronic kidney disease and the risks of death, cardiovascular events, and hospitalization. N Engl J Med 2004; 351: 1296-1305
4. Anavekar NS, McMurray JJ, Velazquez EJ et al. Relation between renal dysfunction and cardiovascular outcomes after myocardial infarction. N Engl J Med 2004; 351: 1285-1295
5. Clayton TC, Lubsen J, Pocock SJ et al. Risk score for predicting death, myocardial infarction, and stroke in patients with stable angina, based on a large randomised trial cohort of patients. BMJ 2005; 331: 869-873
6. Stevens LA, Coresh J, Greene T et al. Assessing kidney function - measured and estimated glomerular filtration rate. N Engl J Med 2006; 354: 2473-2483
7. Asahara T, Masuda H, Takahashi T et al. Bone marrow origin of endothelial progenitor cells responsible for postnatal vasculogenesis in physiological and pathological neovascularization. Circ Res 1999; 85: 221-228
8. Vasa M, Fichtlscherer S, Aicher A et al. Number and migratory activity of circulating endothelial progenitor cells inversely correlate with risk factors for coronary artery disease. Circ Res 2001; 89: e1-e7
9. Hill JM, Zalos G, Halcox JP et al. Circulating endothelial progenitor cells, vascular function, and cardiovascular risk. N Engl J Med 2003; 348: 593-600
10. Schmidt-Lucke C, Rössig L, Fichtlscherer S et al. Reduced number of circulating endothelial progenitor cells predicts future cardiovascular events: proof of concept for the clinical importance of endogenous vascular repair. Circulation 2005; 111: 2981-2987
11. Werner N, Kosiol S, Schiegl T et al. Circulating endothelial progenitor cells and cardiovascular outcomes. N Engl J Med 2005; 353: 999-1007
12. Minami E, Laflamme MA, Saffitz JE et al. Extracardiac progenitor cells repopulate most major cell types in the transplanted human heart. Circulation 2005;112:2951-2958
13. Werner N, Junk S, Laufs U et al. Intravenous transfusion of endothelial progenitor cells reduces neointima formation after vascular injury. Circ Res 2003; 93: e17-e24
14. Aicher A, Heeschen C, Mildner-Rihm C et al. Essential role of endothelial nitric oxide synthase for mobilization of stem and progenitor cells. Nat Med 2003; 9: 1370-1376
15. de Groot K, Bahlmann FH, Bahlmann E et al. Kidney graft function determines endothelial progenitor cell number in renal transplant recipients. Transplantation 2005; 79: 941-945
16. Soler MJ, Martinez-Estrada OM, Marco-Feliu D et al. Circulating endothelial progenitor cells after kidney transplantation. Am J Transplant 2005; 5: 2154-2159
17. Steiner S, Winkelmayer WC, Kleinert J et al. Endothelial progenitor cells in kidney transplant recipients. Transplantation 2006; 81: 599-606
18. de Groot K, Bahlmann FH, Sowa J et al. Uremia causes endothelial progenitor cell deficiency. Kidney Int 2004; 66: 641-646
19. Eizawa T, Murakami Y, Matsui K et al. Circulating endothelial progenitor cells are reduced in hemodialysis patients. Curr Med Res Opin 2003; 19: 627-633
20. Choi JH, Kim KL, Huh W et al. Decreased number and impaired angiogenic function of endothelial progenitor cells in patients with chronic renal failure. Arterioscler Thromb Vasc Biol 2004; 24: 1246-1252
21. Westerweel PE, Hoefer IE, Blankestijn PJ et al. End-stage renal disease causes an imbalance between endothelial and smooth muscle progenitor cells. Am J Physiol 2007; 292: F1132-F1140
22. Herbrig K, Pistrosch F, Oelschlaegel U et al. Increased total number but impaired migratory activity and adhesion of endothelial progenitor cells in patients on long-term hemodialysis. Am J Kidney Dis 2004; 44: 840-849
23. Herbrig K, Gebler K, Oelschlaegel U et al. Kidney transplantation substantially improves endothelial progenitor cell dysfunction in patients with end-stage renal disease. Am J Transplant 2006; 6: 2922-2928
24. Thum T, Tsikas D, Stein S et al. Suppression of endothelial progenitor cells in human coronary artery disease by the endogenous nitric oxide synthase inhibitor asymmetric dimethylarginine. J Am Coll Cardiol 2005; 46: 1693-1701
25. Kunz GA, Liang G, Cuculi F et al. Circulating endothelial progenitor cells predict coronary artery disease severity. Am Heart J 2006; 152: 190-195
26. Güven H, Shepherd RM, Bach RG et al. The number of endothelial progenitor cell colonies in the blood is increased in patients with angiographically significant coronary artery disease. J Am Coll Cardiol 2006; 48: 1579-1587
27. Zebrack JS, Anderson JL, Beddhu S et al. for the Intermountain Heart Collaborative Study Group. Do associations with C-reactive protein and extent of coronary artery disease account for the increased cardiovascular risk of renal insufficiency? J Am Coll Cardiol 2003; 42: 57-63
28. Henry RNA, Kostense PJ, Bos GT et al. Mild renal insufficiency is associated with increased cardiovascular mortality: the Hoorn Study. Kidney Int 2002; 62: 1402-1407
29. George J, Shmilovich H, Deutsch V et al. Comparative analysis of methods for assessment of circulating endothelial progenitor cells. Tissue Eng 2006; 12: 331-335
30. Shintani S, Murohara T, Ikeda H et al. Mobilization of endothelial progenitor cells in patients with acute myocardial infarction. Circulation 2001; 103: 2776-2779
31. George J, Goldstein E, Abashidze S et al. Circulating endothelial progenitor cells in patients with unstable angina: association with systemic inflammation. Eur Heart J 2004; 25: 1003-1008
32. + stem cells, and mononuclear cells expressing early cardiac, muscle, and endothelial markers into peripheral blood in patients with acute myocardial infarction. Circulation 2004; 110: 3213-3220
33. Massa M, Rosti V, Ferrario M et al. Increased circulating hematopoietic and endothelial progenitor cells in the early phase of acute myocardial infarction. Blood 2005; 105: 199-206
34. + endothelial progenitor cells are determinants of subclinical atherosclerosis in a middle-aged general population. Stroke 2006; 37: 2277-2282
35. Gibbons RJ, Abrams J, Chetterjee K et al. ACC/AHA 2002 guideline update for the management of patients with chronic stable angina: a report of the American College of Cardiology/ American Heart Association Task Force on Practice Guidelines. Committee to Update the 1999 Practice Guidelines for the Management of Patients with Chronic Stable Angina, 2002. Available at www.acc.org/guidelines/clinical/stable/stable.pdf (accessed 20 August 2007)
36. Vasa M, Fichtlscherer S, Adler K et al. Increase in circulating endothelial progenitor cells by statin therapy in patients with stable coronary artery disease. Circulation 2001; 103: 2885-2890
37. Min TQ, Zhu CJ, Xiang WX et al. Improvement in endothelial progenitor cells from peripheral blood by ramipril therapy in patients with stable coronary artery disease. Cardiovasc Drugs Ther 2004; 18: 203-209
38. + and endothelial progenitor cells in patients with various degrees of congestive heart failure. Circulation 2004; 110: 1209-1212
39. Sullivan DR, Marwick TH, Freedman SB. A new method of scoring coronary angiograms to reflect extent of coronary atherosclerosis and improve correlation with major risk factors. Am Heart J 1990; 119: 1262-1267
40. Zhu J, Wang X, Chen J et al. Reduced number and activity of circulating endothelial progenitor cells from patients with hyperhomocysteinemia. Arch Med Res 2006; 37: 484-489
41. Gould KL, Lipscomb K. Effects of coronary stenoses on coronary flow reserve and resistance. Am J Cardiol 1974; 34: 48-55
42. Adams V, Lenk K, Linke A et al. Increase of circulating endothelial progenitor cells in patients with coronary artery disease after exercise-induced ischemia. Arterioscler Thromb Vasc Biol 2004; 24: 684-690
43. Stam F, van Guldener C, Becker A et al. Endothelial dysfunction contributes to renal function-associated cardiovascular mortality in a population with mild renal insufficiency: the Hoorn study. J Am Soc Nephrol 2006; 17: 537-545
44. Yamamoto H, Uemura S, Tomoda Y et al. Transcardiac gradient of soluble adhesion molecules predicts progression of coronary artery disease. Int J Cardiol 2002; 84: 249-257
45. Astor BC, Coresh J, Heiss G et al. Kidney function and anemia as risk factors for coronary heart disease and mortality: the Atherosclerosis Risk in Communities (ARIC) Study. Am Heart J 2006; 151: 492-500
46. Vallance P, Leiper J. Cardiovascular biology of the asymmetric dimethylarginine: dimethylarginine dimethylaminohydrolase pathway. Arterioscler Thromb Vasc Biol 2004; 24: 1023-1030
47. Schnabel R, Blankenberg S, Lubos E et al. Asymmetric dimethylarginine and the risk of cardiovascular events and death in patients with coronary artery disease: results from the AtheroGene Study. Circ Res 2005; 97: e53-e59
48. Nanayakkara PW, Teerlink T, Stehouwer CD et al. Plasma asymmetric dimethylarginine (ADMA) concentration is independently associated with carotid intima-media thickness and plasma soluble vascular cell adhesion molecule-1 (sVCAM-1) concentration in patients with mild-to-moderate renal failure. Kidney Int 2005; 68: 2230-2236
49. Marescau B, Nagels G, Possemiers I et al. Guanidino compounds in serum and urine of nondialyzed patients with chronic renal insufficiency. Metabolism 1997; 46: 1024-1031
50. Bode-Böger SM, Scalera F, Kielstein JT et al. Symmetrical dimethylarginine: a new combined parameter for renal function and extent of coronary artery disease. J Am Soc Nephrol 2006; 17: 1128-1134
51. Fehr T, Ammann P, Garzoni D et al. Interpretation of erythropoietin levels in patients with various degrees of renal insufficiency and anemia. Kidney Int 2004; 66: 1206-1211
52. Bahlmann FH, de Groot K, Haller H et al. Erythropoietin: is it more than correcting anaemia? Nephrol Dial Transplant 2004; 19: 20-22
53. Heeschen C, Aicher A, Lehmann R et al. Erythropoietin is a potent physiologic stimulus for endothelial progenitor cell mobilization. Blood 2003; 102: 1340-1346
54. Ferrario M, Massa M, Rosti V et al. Early haemoglobin-independent increase of plasma erythropoietin levels in patients with acute myocardial infarction. Eur Heart J 2007; 28: 1805-1813
55. Radtke HW, Claussner A, Erbes PM et al. Serum erythropoietin concentration in chronic renal failure: relationship to degree of anemia and excretory renal function. Blood 1979; 54: 877-884
56. Prunier F, Pfister O, Hadri L et al. Delayed erythropoietin therapy reduces post-MI cardiac remodeling only at a dose that mobilizes endothelial progenitor cells. Am J Physiol Heart Circ Physiol 2007; 292: H522-H529
57. +, renal anemia, and adverse outcomes. Am Heart J 2006; 152: e21
58. Ikarashi K, Li B, Suwa M et al. Bone marrow cells contribute to regeneration of damaged glomerular endothelial cells. Kidney Int 2005; 67: 1925-1933
59. Uchimura H, Marumo T, Takase O et al. Intrarenal injection of bone marrow-derived angiogenic cells reduces endothelial injury and mesangial cell activation in experimental glomerulonephritis. J Am Soc Nephrol 2005; 16: 997-1004
60. Bai HW, Shi BY, Qian YY et al. Does endothelial chimerism correlate with renal allograft rejection? Transplant Proc 2006; 38: 3430-3433
61. Wassmann S, Werner N, Czech T et al. Improvement of endothelial function by systemic transfusion of vascular progenitor cells. Circ Res 2006; 99: e74-e83
62. Boos CJ, Lip GY, Blann AD. Circulating endothelial cells in cardiovascular disease. J Am Coll Cardiol 2006; 48: 1538-1547
63. Lambiase PD, Edwards RJ, Anthopoulos P et al. Circulating humoral factors and endothelial progenitor cells in patients with differing coronary collateral support. Circulation 2004; 109: 2986-2992
64. Sezer M, Ozcan M, Okcular I et al. A potential evidence to explain the reason behind the devastating prognosis of coronary artery disease in uraemic patients: renal insufficiency is associated with poor coronary collateral vessel development. Int J Cardiol 2007; 115: 366-372
65. Erbs S, Linke A, Schächinger V et al. Restoration of microvascular function in the infarct-related artery by intracoronary transplantation of bone marrow progenitor cells in patients with acute myocardial infarction: the Doppler Substudy of the Reinfusion of Enriched Progenitor Cells and Infarct Remodeling in Acute Myocardial Infarction (REPAIR-AMI) trial. Circulation 2007; 116: 366-374
66. Schächinger V, Erbs S, Elsässer A et al. Intracoronary bone marrow-derived progenitor cells in acute myocardial infarction. N Engl J Med 2006; 355: 1210-1221
67. Urao N, Okigaki M, Yamada H et al. Erythropoietin-mobilized endothelial progenitors enhance reendothelialization via AKt-endothelial nitric oxide synthase activation and prevent neointimal hyperplasia. Circ Res 2006; 98: 1405-1413
68. Westenbrink BD, Lipsic E, van der Meer P et al. Erythropoietin improves cardiac function through endothelial progenitor cell and vascular endothelial growth factor mediated neovascularization. Eur Heart J 2007; 28: 2018-2027
69. Heiss C, Keymel S, Niesler U et al. Impaired progenitor cell activity in age-related endothelial dysfunction. J Am Coll Cardiol 2005; 45: 1441-1448
70. Khan SS, Solomon MA, McCoy JP Jr. Detection of circulating endothelial cells and endothelial progenitor cells by flow cytometry. Cytometry B Clin Cytom 2005; 64: 1-8
71. Lin Y, Weisdorf DJ, Solovey A et al. Origins of circulating endothelial cells and endothelial outgrowth from blood. J Clin Invest 2000; 105: 71-77
72. Ingram DA, Mead LE, Tanaka H et al. Identification of a novel hierarchy of endothelial progenitor cells using human peripheral and umbilical cord blood. Blood 2004; 104: 2752-2760
73. Rehman J, Li J, Orschell CM et al. Peripheral blood "endothelial progenitor cells" are derived frommonocyte/macrophages and secrete angiogenic growth factors. Circulation 2003; 107: 1164-1169