Kidney transplantation substantially improves endothelial progenitor cell dysfunction in patients with end-stage renal disease

American Journal of Transplantation

Volumn 6, Issue 12, 2006, Pages 2922-2928

  Herbrig, K ^a   Gebler, K ^a   Oelschlaegel, U ^a   Pistrosch, F ^a   Foerster, S ^a   Wagner, A ^a   Gross, P ^a   Passauer, J ^a  

^a DRESDEN UNIVERSITY OF TECHNOLOGY   (Germany)

Author keywords

End stage renal disease; Endothelial progenitor cells; Kidney transplantation

Indexed keywords

COLLAGEN TYPE 4; FIBRONECTIN;

ADULT; ARTICLE; CELL ADHESION; CELL FUNCTION; CELL MIGRATION; CLINICAL ARTICLE; CONTROLLED STUDY; DIALYSIS; ENDOTHELIUM CELL; FEMALE; FLOW CYTOMETRY; HUMAN; KIDNEY FAILURE; KIDNEY TRANSPLANTATION; MALE; MORBIDITY; PRIORITY JOURNAL; STEM CELL;

ADULT; CELL MOVEMENT; CHEMOKINES, CXC; ENDOTHELIUM, VASCULAR; FEMALE; FLOW CYTOMETRY; HUMANS; KIDNEY FAILURE, CHRONIC; KIDNEY TRANSPLANTATION; MALE; MIDDLE AGED; REFERENCE VALUES; STEM CELLS; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 33751181185     PISSN: 16006135     EISSN: 16006143     Source Type: Journal    
DOI: 10.1111/j.1600-6143.2006.01555.x     Document Type: Article

References (40)

1. Foley RN, Parfrey PS, Sarnak MJ. Epidemiology of cardiovascular disease in chronic renal disease. J Am Soc Nephrol 1998; 9: 16-23.
2. Kari JA, Donald AE, Vallance DT et al. Physiology and biochemistry of endothelial function in children with chronic renal failure. Kidney Int 1997; 52: 468-472.
3. Passauer J, Bussemaker E, Range U, Plug M, Gross P. Evidence in vivo showing increase of baseline nitric oxide generation and impairment of endothelium-dependent vasodilation in normotensive patients on chronic hemodialysis. J Am Soc Nephrol 2000; 11: 1726-1734.
4. Asahara T, Masuda H, Takahashi T et al. Isolation of putative progenitor endothelial cells for angiogenesis. Science 1997; 275: 964-967.
5. Kalka C, Masusa H, Takahashi T et al. Transplantation of ex vivo expanded endothelial progenitor cells for therapeutic neovascularization. Proc Natl Acad Sci U S A 2000; 97: 3422-3427.
6. Assmus B, Schachinger V, Teupe C et al. Transplantation of progenitor cells and regeneration enhancement in acute myocardial infarction (TOPCARE-AMI). Circulation 2002; 10: 3009-3017.
7. Urbich C, Heeschen C, Aicher A et al. Relevance of monocytic features for neovacularization capacity of circulating endothelial progenitor cells. Circulation 2003; 108: 2511-2516.
8. Hill JM, Zalos G, Halox JP et al. Circulating endothelial progenitor cells, vascular function, and cardiovascular risk. N Engl J Med 2003; 348: 593-600.
9. Vasa M, Fichtlscherer S, Aicher A et al. Number and migratory activity of circulating endothelial progenitor cells inversely correlate with risk factors for coronary artery disease. Circ Res 2001; 89: E1-E7.
10. Werner N, Kosiol S, Schiegl T et al. Circulating endothelial progenitor cells and cardiovascular outcomes. N Engl J Med 2005; 353: 999-1007.
11. Herbrig K, Pistrosch F, Oelschlaegel U et al. Increased total number but impaired migratory activity and adhesion of endothelial progenitor cells in patients on long-term hemodialysis. Am J Kidney Dis 2004; 44: 840-849.
12. Choi JH, Kim KL, Huh W et al. Decreased number and impaired angiogenic function of endothelial progenitor cells in patients with chronic renal failure. Arterioscler Thromb Vasc Biol 2004; 24: 1246-1252.
13. Wolfe RA, Ashby VB, Milford EL et al. Comparison of mortality in all patients on dialysis, patients on dialysis awaiting transplantation, and recipients of a first cadaveric transplant. N Engl J Med 1999; 341: 1725-1730.
14. Passauer J, Bussemaker E, Lassig G, Gross P. Kidney transplantation improves endothelium-dependent vasodilation in patients with end stage renal disease. Transplantation 2003; 15: 1907-1910.
15. Covic A, Goldsmith DJ, Gusbeth-Tatomir P, Buhaescu I, Covic M. Successful renal transplantation decreases aortic stiffness and increases vascular reactivity in dialysis patients. Transplantation 2003; 76: 1573-1577.
16. Sarnak MJ, Levey AS, Schoolwerth AC et al. Kidney disease as a risk factor for development of cardiovascular disease: A statement from the American Heart Association Councils on kidney in cardiovascular disease, high blood pressure research, clinical cardiology, and epidemiology and prevention. Circulation 2003; 108: 2154-2169.
17. Steiner S, Winkelmayer WC, Kleinert J et al. Endothelial progenitor cells in kidney transplant recipients. Transplantation 2006; 27: 599-606.
18. Groot K, Bahlmann FH, Bahlmann E et al. Kidney graft function determines endothelial progenitor number in renal transplant recipients. Transplantation 2005; 79: 941-945.
19. Soler MJ, Martinez-Estrada OM, Puig-Mari JM et al. Circulating endothelial progenitor cells after kidney transplantation. Am J Transplant 2005; 9: 2154-2159.
20. Voermans C, Kooi ML, Rodenhuis S et al. In vitro migratory capacity of CD34+ cells is related to hematopoietic recovery after autologous stem cell transplantation. Blood 2001; 97: 799-804.
21. Herbrig K, Pistrosch F, Foerster S et al. Endothelial progenitor cells in chronic renal insufficiency. Kidney Blood Press Res 2006; 29: 24-31.
22. Herbrig K, Haensel S, Oelschlaegel U et al. Endothelial dysfunction in patients with rheumatoid arthritis is associated with a reduced number and impaired function of endothelial progenitor cells. Ann Rheum Dis 2006; 65: 157-163.
23. Aicher A, Zeiher AM, Dimmeler S. Mobilizing endothelial progenitor cells. Hypertension 2005; 45: 321-325.
24. Urbich C, Dimmeler S: Endothelial progenitor cells: Characterization and role in vascular biology. Circ Res 2004; 95: 343-353.
25. de Groot K, Bahlmann FH, Sowa J et al. Uremia causes endothelial progenitor cell deficiency. Kidney Int 2004; 66: 641-646.
26. Tepper OM, Galiano RD, Capla JM et al. Human endothelial progenitor cells from type II diabetics exhibit impaired proliferation, adhesion, and incorporation into vascular structures. Circulation 2002; 106: 2781-2786.
27. Chen J, Zhang F, Tao Q et al. Number and activity of endothelial progenitor cells from peripheral blood in patients with hypercholesterolemia. Clin Sci (Lond) 2004; 107: 273-280.
28. Cerini C, Dou L, Anfosso F et al. P-cresol, a uremic retention solute, alters the endothelial barrier function in vitro. Thromb Haemost 2004; 92: 140-150.
29. Dou L, Bertrand E, Cerini C et al. The uremic solutes p-cresol and indoxyl sulfate inhibit endothelial proliferation and wound repair. Kidney Int 2004; 65: 442-451.
30. Ceradini DJ, Kulkarni AR, Callaghan MJ et al. Progenitor cell trafficking is regulated by hypoxic gradients through HIF-1 induction of SDF-1. Nat Med 2004; 10: 858-864.
31. van Buul JD, Voermans C, van Geldern J et al. Leukocyte-endothelium interaction promotes SDF-1 dependent polarization of CXCR4. J Biol Chem 2003; 278: 30302-30310.
32. Walter DH, Haendeler J, Reinhold J et al. Impaired CXCR4 signaling contributes to the reduced neovascularization capacity of endothelial progenitor cells from patients with coronary artery disease. Circ Res 2005; 97: 1142-1151.
33. Rafiee P, Heidemann J, Ogawa H et al. Cyclosporin A differentially inhibits multiple steps in VEGF induced angiogenesis in human microvascular endothelial cells through altered intracellular signalling. Cell Commun Signal 2004; 2: 3.
34. Hernandez GL, Volpert OV, Iniguez MA et al. Selective inhibition of vascular endothelial growth factor-mediated angiogenesis by cyclosporine A: Roles of the nuclear factor of activated T cells and cyclooxygenase 2. J Exp Med 2001; 193: 607-620.
35. Bahlmann FH, de Groot K, Spandau JM et al. Erythropoietin regulates endothelial progenitor cells. Blood 2004; 103: 921-926.
36. Bahlmann FH, de Groot K, Duckert T et al. Endothelial progenitor cell proliferation and differentiation is regulated by erythropoietin. Kidney Int 2003; 64: 1648-1652.
37. Eizawa T, Murakami Y, Matsui M et al. Circulating endothelial progenitor cells are reduced in hemodialysis patients. Curr Med Res Opin 2003; 19: 627-633.
38. Chan CT, Li Sh, Verma S. Nocturnal hemodialysis is associated with restoration of impaired endothelial progenitor cell biology in end-stage renal disease. Am J Physiol Renal Physiol 2005; 289: F679-F684.
39. Steiner S, Schaller G, Puttinger H et al. History of cardiovascular disease is associated with endothelial progenitor cells in peritoneal dialysis patients. Am J Kidney Dis 2005; 46: 520-528.
40. Kocak H, Ceken K, Avuz A et al. Effect of renal transplantation on endothelial function in haemodialysis patients. Nephrol Dial Transplant 2006; 21: 203-207.